Scientists Determine How Hepatitis B&D Enter Liver Cells (BioScholar)

Inside eLife
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Liver diseases related to the human hepatitis B virus (HBV) kill about 1 million people every year, and more than 350 million people around the world are infected with the virus. Some 15 million of these people are also infected with the hepatitis D virus (HDV), which is a satellite virus of HBV, and this places them at an even higher risk of liver diseases, including cancer. The viruses are known to enter liver cells by binding to receptors on their surface before being engulfed.

In an eLife study, published today, scientists have filled a major gap in our understanding of hepatitis B and D: they've identified the receptor that allows hepatitis B and hepatitis D viruses to enter human liver cells.

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