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19,270 results found
    1. Structural Biology and Molecular Biophysics

    Two Glu/Asp residues cooperatively mediate an early step of ATP hydrolysis in GHKL ATPases MutL and GyrB

    Kenji Fukui, Ayaka Shibuya ... Takato Yano
    A cooperative catalytic mechanism provides a revised framework for understanding ATP hydrolysis in a broad subset of GHKL ATPases.
    1. Neuroscience

    Retinal curl as a functional signal for heading estimation beyond the focus of expansion

    Kontessa I Zorpala, Joan López-Moliner
    The rotational retinal flow generated by natural gaze stabilization is not merely visual noise to be subtracted but actively shapes human heading perception.
    1. Epidemiology and Global Health

    Responsible Research Assessment of Faculty: maximizing quality, transparency, and trustworthiness of scientific research in Research-Performing Organizations

    David Moher, Kelly D Cobey ... David Mellor
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology

    Glycolipid MPIase is essential for the TAT (Twin-Arginine Translocation) pathway

    Hanako Nishikawa, Nachi Yamamoto ... Ken-ichi Nishiyama
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

    Kuei Ching Hsiung, Hannah Chapman ... David Gems
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Large scale prospective evaluation of co-folding across hundreds of Mac1-ligand complexes and three virtual screens

    Jongbin Kim, Galen J Correy ... James S Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring

    Vincent Hisler, Lana Rees ... Anna Jaźwińska
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Convincing
    1. Neuroscience

    Multiplexed CRISPRi Reveals a Transcriptional Switch Between KLF Activators and Repressors in the Maturing Neocortex

    Ryan W Kirk, Liwei Sun ... Sacha Nelson
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Decreased Astrocytic CCL5 by MiR-324-5p Ameliorates Ischemic Stroke Injury via the CCR5/ERK/CREB Pathway

    Jingxiu Li, Keyuan Gao ... Chenxi Sun
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Real-time closed-loop feedback system for mouse mesoscale cortical signal and movement control

    Pankaj Kumar Gupta, Timothy H Murphy
    The open-source closed-loop system enables mice to learn modulation of cortical activity or movement by providing a platform for testing brain-behavior relationships in motor learning and neurorehabilitation research.
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