Browse the latest research

18,436 results found
    1. Genetics and Genomics
    2. Cancer Biology

    Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

    Olivia G Waltner, April A Apfelbaum ... Scott N Furlan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Epidemiology and Global Health

    Atovaquone/Proguanil Use and Zoster Vaccination Are Associated with Reduced Alzheimer’s Disease Risk in Two Cohorts: Implications for a Latent Toxoplasma gondii Mechanism

    Ariel Israel, Abraham Weizman ... Eugene Merzon
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Serratia marcescens Outer Membrane Vesicles rapidly paralyze Drosophila melanogaster through triggering apoptosis in the nervous system

    Bechara Sina Rahme, Roberto E Bruna ... Dominique Ferrandon
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology

    Junctional and Actomyosin Dynamics Drive Endothelial Cell Rearrangements during Vascular Tube Formation

    Heinz-Georg Belting, Ludovico Maggi ... Markus Affolter
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Coordinated spinal locomotor network dynamics emerge from cell-type-specific connectivity patterns

    F David Wandler, Benjamin K Lemberger ... James M Murray
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Biophysical basis for brain folding and misfolding patterns in ferrets and humans

    Gary PT Choi, Chunzi Liu ... L Mahadevan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology
    2. Evolutionary Biology

    Punctuated mutagenesis promotes multi-step evolutionary adaptation in human cancers

    Christopher Graser, Wenbo Wu ... Franziska Michor
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

    Sofia Lövestam, Jane L Wagstaff ... Sjors HW Scheres
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Convincing
    1. Neuroscience

    Neural correlates and reinstatement of recent and remote memory in children and young adults

    Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing
    Children show less robust memory retention overnight and after 2 weeks, with memories transforming more rapidly from detailed to gist-like neural representations, revealing less stable consolidation mechanisms than in adults.
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