The brain computes rapidly and reliably using brief electrical impulses and likely exploits internal memory in nerve cells to achieve this more efficiently than existing computing hardware and neural networks.
Isabelle G Henshall, Jill Chmielewski ... Danny W Wilson
Pathogens can use surface proteins to limit immune responses, and the finding that merozoite surface protein 2 has this property could help in Plasmodium falciparum malaria vaccine development.
Kely Catarine Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli
TNF-driven metabolic reprogramming enhances glucose utilization in monocytes through inducible nitric oxide synthase (iNOS) and hypoxia-inducible factor 1α (HIF-1α), promoting parasite control and host resistance during Plasmodium infection.
Tamar Basiashvili, Joshua Hutchings ... Elizabeth Villa
Type I and type II inhibitors differentially affect LRRK2 filament formation around microtubules, revealing an important consideration for Parkinson’s disease drug development.
Flexible evidence accumulation in dynamic environments relies on multiple mechanisms, including context-dependent modulations of sensory adaptation and pupil-linked arousal.
