Browse the latest research

18,522 results found
    1. Neuroscience

    Mouse sensorimotor cortex reflects complex kinematic details during reaching and grasping

    Harrison A Grier, Sohrab Salimian, Matthew T Kaufman
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics

    Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner

    Liana Senaldi, Nora Hassan ... Matthew Smith-Raska
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Physics of Living Systems

    Division Asymmetry Drives Cell Size Variability in Budding Yeast

    Félix Proulx-Giraldeau, Xin Gao ... Paul Francois
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Physics of Living Systems

    Interplay Between Pulmonary Membrane Properties and Lung Disease: A Study of Seven Bottlenose Dolphins

    Marilyn Porras-Gómez, Bengu Sueda Sengul ... Cecília Leal
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Synaptic Theory of Chunking in Working Memory

    Weishun Zhong, Mikhail Katkov, Misha Tsodyks
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Short activation domains control chromatin association of transcription factors

    Vinson B Fan, Abrar A Abidi ... Max V Staller
    Single-molecule tracking of transcription factors in living cells revealed how mutations that make short activation domains stronger increased the fraction of transcription factor molecules bound to chromatin and led to longer residence times on chromatin.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Affinity-guided labeling reveals P2X7 nanoscale membrane redistribution during BV2 microglial activation

    Benoit Arnould, Adeline Martz ... Thomas Grutter
    An affinity-guided chemical strategy enabling highly specific biotinylation of P2X7 receptors reveals, by super-resolution microscopy, how the nanoscale organization of endogenous P2X7 in BV2 microglial cells dynamically changes upon activation.
    1. Biochemistry and Chemical Biology

    The interplay between biomolecular assembly and phase separation

    Giacomo Bartolucci, Ivar S Haugerud ... Christoph A Weber
    Biomolecular assembly typically promotes phase separation while the presence of coexisting phases alters assembly kinetics.
    1. Neuroscience

    Two classes of amine/glutamate multi-transmitter neurons innervate Drosophila internal male reproductive organs

    Marta Chaverra, John Paul Toney ... R Steven Stowers
    Drosophila internal male reproductive organs exhibit parallel innervation by two types of multi-transmitter neurons, a subset of which are essential for fertility, and organ-specific spatially discrete neurotransmitter receptor expression.
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference reveal that the apterous Early enhancer is required for developmental boundary positioning

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling

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