Browse the latest research

19,034 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules

    Mariam Ahmed Fouad, Christopher S Parry ... John Karanicolas
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Cell Biology
    2. Genetics and Genomics

    Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain

    Rubina Dad, Yujuan Wang ... Hui-Yuan Wu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Noise in Competing Representations Determines the Direction of Memory Biases

    Andrey Chetverikov, Sabrina Hansmann-Roth
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Ecology

    Coordinated beak–tongue mechanics enable dexterous seed manipulation in songbirds

    Maja Mielke, Falk Mielke ... Sam Van Wassenbergh
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Heritability of movie-evoked brain activity and connectivity

    David C Gruskin, Daniel J Vieira ... Gaurav H Patel
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Physics of Living Systems

    Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

    Daniel Haertter, Lara Hauke ... Christoph F Schmidt
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Rehabilitation drives functional reorganization of intact corticospinal-supraspinal projections following partial spinal cord injury

    James Bonanno, Sheel Trivedi ... William BJ Cafferty
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Neuroscience

    SqueakPose Studio, an end-to-end platform for pose estimation and real-time edge-AI deployment

    David L Haggerty, Caleb Browning Darden, David Lovinger
    Integrated pose estimation, video acquisition, and edge deployment tools make real-time behavioral analysis more accessible to neuroscience laboratories.
    1. Cell Biology
    2. Genetics and Genomics

    Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

    Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann
    Genetic experiments integrated with ChIP-sequencing and CRISPR interference reveal that overexpression of Foxc1 transcriptionally activates the expression of Arhgap36 and dysregulates multiple facets of Hedgehog pathway activity.
    1. Cell Biology
    2. Computational and Systems Biology

    Lipid packing contributes to the confinement of caveolae to the plasma membrane

    Elin Larsson, Aleksei Kabedev ... Richard Lundmark
    Membrane insertion of Dyngo-4a results in a dynamin-independent inhibition of caveola dynamics, revealing that outer leaflet lipid packing in the plasma membrane contributes to the confinement of caveolae.
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