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19,251 results found
    1. Stem Cells and Regenerative Medicine

    Synergistic inhibition of Notch signaling and forced cell cycle re-entry drive Müller glia reprogramming in uninjured mouse retina

    Baoshan Liao, Chengshang Lyu ... Wenjun Xiong
    Stimulating cell cycle entry and suppressing Notch signaling drive mammalian Müller glia to proliferate and generate diverse, long-surviving neuron-like cells, offering insights into overcoming retinal regeneration barriers.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Screening the MMV Pathogen Box reveals the mitochondrial bc1-complex as a drug target in mature Toxoplasma gondii bradyzoites

    Deborah Maus, Elyzana Putrianti ... Martin Blume
    Inhibiting the mitochondrial bc1-complex disrupts energy production in mature Toxoplasma gondii bradyzoites, suggesting a metabolic vulnerability in the parasite's chronic, drug-resistant stage.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Convincing
    1. Cell Biology
    2. Neuroscience

    TRPML1 positions lysosomes and regulates actin-membrane linkers in astrocyte processes

    Maeve L Spivey, Madison L Fuller ... Sandra Maday
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    E-Selectin Orchestrates IL-1β–Dependent Neuroinflammation via NLRP3 in Vincristine-Induced Neuropathy

    Hana Starobova, Ammar Alshammari ... Irina Vetter
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Two Glu/Asp Residues Cooperatively Mediate an Early Step of ATP Hydrolysis in GHKL ATPases MutL and GyrB

    Kenji Fukui, Ayaka Shibuya ... Takato Yano
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Virus specific impacts on honey bee flight performance are mediated by the octopamine pathway

    Naomi G Kaku, Michelle L Flenniken
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Symmetric brain-liver circuits mediate lateralized regulation of hepatic glucose output in mice

    Zhonglong Wang, Xiangfei Gong ... Hao Xie
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    • Solid
    1. Neuroscience

    Asymmetric neural entrainment at resonance frequencies underlies unilateral spatial neglect

    Yuka O Okazaki, Noriaki Hattori ... Keiichi Kitajo
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    A cortical–hippocampal communication undergoes rebalancing after new learning

    Arron F Hall, Dong V Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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