Catalytic inhibition of tankyrase induces tankyrase accumulation and rigidifies the β-catenin destruction complex, limiting its ability to suppress WNT signaling.
Tobias Kaufmann, Pål Marius Bjørnstad ... Timothy Hughes
Previously overlooked information in standard head MRI scans combined with a novel deep learning method enables large-scale investigation of human bone marrow biology across existing imaging cohorts.
Spyglass transforms neuroscience datasets into a foundation for discovery, enabling researchers to verify findings, test new ideas, share results, and build knowledge that extends beyond any single experiment or laboratory.
