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18,806 results found
    1. Developmental Biology

    Cdhr1a and pcdh15b may link photoreceptor outer segments with calyceal processes revealing a potential mechanism for cone-rod dystrophy

    Meet K Patel, Warlen Pereira Piedade, Jakub K Famulski
    Zebrafish cone photoreceptor outer segment integrity may be regulated by the interactions between the outer segments and calyceal processes mediated by retinal cadherins cdhr1a and pcdh15b.
    1. Microbiology and Infectious Disease

    Membrane Binding Controls the ATPase Cycle and Localization of MinD in Bacillus subtilis

    Helge Feddersen, Charlotte Dyckmanns, Marc Bramkamp
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Beyond the Focus of Expansion: Retinal curl as a functional signal for heading estimation

    Kontessa I Zorpala, Joan López-Moliner
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Neuroscience

    Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability

    Simone Carneiro-Nascimento, Chao Wei ... Dan Levy
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cancer Biology

    Acquired resistance to sotorasib in KRASG12C mutant NSCLC is vulnerable to PI3K-mTOR pathway inhibition mediated by 4E-BP1, a regulator of cap-dependent translation

    Ismail M Meraz, Shuhong Wu ... Jack A Roth
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Prolonged oscillating preoptic area kisspeptin neuron activity underlies the preovulatory luteinizing hormone surge in mice

    Ziyue Zhou, Cheng-Yu Huang, Allan E Herbison
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Immunology and Inflammation

    Heat shock factor regulation of antimicrobial peptides expression suggests a conserved defense mechanism induced by febrile temperature in arthropods

    Bang Xiao, Shihan Chen ... Chaozheng Li
    Febrile temperatures enhance antiviral immunity through heat shock factor-dependent antimicrobial peptides across arthropods.
    1. Ecology

    Geomagnetic and visual cues guide seasonal migratory orientation in the nocturnal fall armyworm, the world’s most invasive insect

    Yi-Bo Ma, Guijun Wan ... Gao Hu
    Behavioral evidence demonstrates that geomagnetic and visual cues are integrated to guide nocturnal migratory insects.
    1. Microbiology and Infectious Disease

    Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa

    Jiadai Huang, Yue Sun ... Xin Deng
    Systematic ChIP-seq profiling of 172 transcription factors in Pseudomonas aeruginosa reveals a hierarchical regulatory architecture governing virulence and establishes a searchable database to guide antimicrobial drug discovery.
    1. Microbiology and Infectious Disease

    Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite development

    Pascale Pescher, Thibaut Douché ... Gerald F Späth
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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