Browse the latest research

19,370 results found
    1. Neuroscience

    Specific Sensitivity to Rare and Extreme Events: Quasi-Complete Black Swan Avoidance vs Partial Jackpot Seeking in Rat Decision-Making

    Mickaël Degoulet, Louis-Matis Willem ... Patrick A Pintus
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Evolutionary Biology

    Super compensatory substitutions restore protein function and confer mutational robustness

    Wenhong Jiang, Hengchuang Yin ... Lucas B Carey
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    SPEx: Compartment-Resolved Proteomics via Expansion Microscopy–Guided Microdissection

    Curdin A Franziscus, Alexia Ferrand ... Anne Spang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    NAD boosting mediated by CD38 inhibition drives reversal of a pathological vicious cycle of intracrine activity and inflammation in eyelid meibomian gland dysfunction

    Yuki Hamada, Takehide Sakamoto ... Masao Doi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    ATP8B1–TMEM30B Flippase Activity Maintains Stereocilia Lipid Asymmetry Required for Hearing

    Henry N De Hoyos, Sihan Li ... Jung-Bum Shin
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology

    Chromatin priming and Hunchback recruitment integrate spatial and temporal cues in Drosophila neuroblasts

    Ayanthi Bhattacharya, Hemalatha Rao, Sonia Q Sen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    Human giant GTPase GVIN1 forms an antimicrobial coatomer around the intracellular bacterial pathogen Burkholderia thailandensis

    Weilun Guo, Shruti S Apte ... Jörn Coers
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Microbiology and Infectious Disease

    Virus-specific impacts on honey bee flight performance are mediated by the octopamine pathway

    Naomi G Kaku, Michelle L Flenniken
    Differential virus-specific impacts on honey bee flight performance involve octopamine signaling, and chemical stressors affecting this pathway may impact colony health.
    1. Neuroscience

    Dual-feature selectivity enables bidirectional coding in visual cortical neurons

    Nikos Karantzas, Katrin Franke ... Andreas Savas Tolias
    Many visual cortical neurons are excited by one feature and suppressed by another, encoding stimuli bidirectionally around an elevated baseline in macaques and mice.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The nuclear membrane protein Samp1 links peripheral genome organization to the myogenic transcriptional program

    Urška Kašnik, Irene Mei ... Einar Hallberg
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
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