Browse the latest research

19,101 results found
    1. Immunology and Inflammation

    ImPaqT, a Golden Gate-based immunological toolkit for zebrafish transgenesis

    Saskia Hurst, Christiane Dimmler, Mark R Cronan
    ImPaqT is an immune toolkit that enables modular and expandable cloning of zebrafish transgenes using Golden Gate-based cloning techniques.
    1. Developmental Biology
    2. Computational and Systems Biology

    Single-cell spatial mapping reveals reproducible cell type organization and spatially-dependent gene expression in gastruloids

    Catherine G Triandafillou, Pranav Sompalle ... Arjun Raj
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Exceptional
    1. Neuroscience

    Multi-area activity in mouse motor cortex associated with one- and two-handed oromanual dexterity

    John M Barrett, Joshua I Glaser ... Gordon MG Shepherd
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Cancer Biology

    Adaptive plasticity of aspartate metabolism in succinate dehydrogenase-deficient cancer cells

    David Sokolov, Eric Zheng ... Lucas B Sullivan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Developmental Synchrony of Retinal Waves, Apoptosis, and Angiogenesis in Postnatal Retina

    Michael A Savage, Cori Bertram ... Evelyne Sernagor
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Multidimensional in vitro assay for antimalarial combination testing and pharmacodynamic modeling – the MULT-i2 assay

    Angela Hellingman, Christin Gumpp ... Matthias Rottmann
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Excitatory cholecystokinin neurons in the CA3 area regulate the navigation learning and neuroplasticity

    Fengwen Huang, Abdul Baset, Stephen Temitayo Bello
    Cholecystokinin release from CA3 inputs to CA1 links local excitatory circuitry to hippocampal plasticity and spatial memory.
    1. Medicine

    Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

    Lu Xiao, Lu Li ... Jia Xiao
    MgIG directly targets HSD11B1 to alleviate alcohol-associated liver disease by suppressing the HSD11B1–SREBP2–IDI1 pathway, thereby reducing hepatic steatosis, inflammation, and apoptosis.

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