Browse the latest research

19,091 results found
    1. Developmental Biology

    MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanism

    Yibing Bao, Zhenzi Zuo ... Chao Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Zapit: Open Source Laser-Scanning Photostimulation For Neuroscience

    Michael Lohse, Oliver M Gauld ... Robert AA Campbell
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Microbiology and Infectious Disease

    Three metabolic pathways replenishing the one-carbon pool collectively support growth and virulence of Listeria monocytogenes

    Sandra Freier, Sarah Frentzel ... Sven Halbedel
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Identification of key Y4R residues enables the discovery of selective non-peptide small-molecule agonists

    Tim Pelczyk, Corinna Schüß ... Annette G Beck-Sickinger
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A tool to pulse-label yeast Nuclear Pore Complexes in imaging and biochemical experiments

    Annemiek C Veldsink, Jonas S Fischer ... Liesbeth M Veenhoff
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Plant Biology
    2. Ecology

    Asymmetric introgression and thermal advantage jointly drive climate-mediated lineage turnover in a mixed-ploidy reed

    Lele Liu, Wenyi Sheng ... Weihua Guo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Enteropathogenic Escherichia coli-mediated fast and coordinated Ca²+ responses regulate NF-κB activation

    Fangrui Guo, Roberto Ornelas Guevara ... Guy Tran Van Nhieu
    Through low levels of extracellular ATP, EPEC induces small, rapid and coordinated Ca2+ responses in epithelial cells, a yet unreported pattern, that down-regulate inflammation at the onset of infection.
    1. Neuroscience

    PKMζ-PKCι/λ double-knockout demonstrates atypical PKC is crucial for the persistence of hippocampal LTP and spatial memory

    Panayiotis Tsokas, Changchi Hsieh ... Todd Charlton Sacktor
    Double-knockout of PKMζ and the other atypical PKC, PKCι/λ, reveals that, without PKMζ for maintenance, PKCι/λ becomes persistently active to sustain hippocampal late-LTP and long-term memory.
    1. Neuroscience

    Two time scales of adaptation in human learning rates

    Jonas Simoens, Senne Braem ... Tom Verguts
    Humans adapt learning rates on both a fast and a slow time scale, and the central orbitofrontal cortex may represent the slow time scale.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct prokaryotic gut microbiome and proviral-immune axes of pathophysiology in Sickle Cell Disease

    Zachary N Flamholz, Jennifer De Los Santos ... Libusha Kelly
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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