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How do you combine the benefits of rapid, open-access publishing with the virtues of rigorous peer review and editorial oversight? eLife is showing how, under the leadership of a Nobel laureate, Randy Schekman, and a team of distinguished senior editors, including Eve Marder, Head of our Division of Science. Eve’s colleagues in Biology are also helping to make eLife a success. Leslie Griffith, Sacha Nelson, and Bruce Goode have served as peer reviewers, and a dozen Brandeis faculty have contributed articles. eLife is a powerful demonstration of the new possibilities for scholarly publishing — and of the continuing strength of the life sciences at Brandeis.