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On January 10, James Manley, Carol Prives (both Columbia University, USA) and Kevin Struhl (Harvard Medical School, USA) discussed their latest research on gene regulation at an event hosted by eLife at the Francis Crick Institute in London, UK.
During the event, Manley highlighted his work on dysregulated mRNA splicing and the role of this process in human disease; Prives discussed the regulation of the p53 network in cancer cells; and Struhl presented his findings on the structural differences between closely related 3’ mRNA isoforms, and their links to Pab1 protein binding and mRNA stability. Their talks were well received and followed by a Q&A session, facilitated by eLife Associate Features Editor Stuart King.
You can watch the full recording of the event below.