Scientists at Penn State University have discovered how a vital step in the human DNA replication process – the loading of molecular structures known as sliding clamps onto DNA molecules – is performed.
The researchers say their work, the results of which were published in Tuesday’s edition of the journal eLife, will help uncover some of the mystery surrounding this crucial part of the chemical replication process. This step had not previously been closely analyzed in human DNA replication, which is the basis for biological inheritance in all types of living organisms.
