Editors for Biochemistry and Chemical Biology

We aim to publish studies that provide new mechanistic insights into the structure, function, and regulation of biological molecules including proteins, nucleic acids, lipids, carbohydrates, and natural products. In addition, we are interested in studies that illuminate complex biological processes using chemical tools and approaches. Read the latest research in this subject area.

Senior editors

  1. Anna Akhmanova

    Anna Akhmanova

    Utrecht University, Netherlands

    Anna Akhmanova is a Professor of Cell Biology at the Department of Biology, Faculty of Science, Utrecht University, the Netherlands. She studied biochemistry and molecular biology at the Moscow State University and obtained her PhD at the University of Nijmegen, the Netherlands. Akhmanova studies cytoskeletal organization and trafficking processes, which contribute to cell polarization, differentiation, vertebrate development and human disease. The main focus of the work in her group is the microtubule cytoskeleton. Research in the group relies on combining high-resolution live cell imaging and quantitative analysis of cytoskeletal dynamics with in vitro reconstitution experiments. Her work has resulted in identification and characterization of a broad variety of factors which control microtubule organization and dynamics and motor attachment to membrane organelles. Anna Akhmanova is an elected member of the European Molecular Biology Organization and the Royal Netherlands Academy of Arts and Sciences.

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Research focus
    cytoskeleton
    cytoskeletal dynamics
    microtubules
    microtubule-binding proteins
    motor proteins
    membrane transport
    cell migration
    Experimental organism
    human cells
    mouse
    Competing interests statement
    Anna Akhmanova receives funding from the European Research Council, Human Frontier Science Program, and the Netherlands Organization for Scientific Research. She is a member of the Scientific Advisory Board of the Netherlands Institute for Neuroscience. She served on the editorial boards of BMC Cell Biology and Journal of Biological Chemistry. She is a currently on the editorial boards of PLOS Biology, Journal of Cell Science, Traffic, and BioArchitecture.
  2. Richard Aldrich

    Richard Aldrich

    The University of Texas at Austin, United States

    Rick Aldrich is the Karl Folkers Chair II in Interdisciplinary Biomedical Research and Professor of Neuroscience at The University of Texas at Austin. He joined the faculty in 2006 and served as chair until 2011. Previously he was on the faculty of Neurobiology (1985-1990) and of Molecular and Cellular Physiology (1990-2006) at Stanford University where he served as department chair from 2001–2004. He was an investigator with the Howard Hughes Medical Institute from 1990 to 2006. His work is on molecular mechanisms of ion channels and calcium signaling proteins, with an emphasis on understanding gated conformational changes and allosteric mechanisms. Work in the laboratory is multidisciplinary including electrophysiology, biochemistry, spectroscopy, informatics and computation. He is a member of the National Academy of Science and the American Academy of Arts and Sciences, and is a Fellow of the American Association for the Advancement of Science and of the Biophysical Society. He is past president of the Biophysical Society and the Society of General Physiologists, and has received the Kenneth Cole Award for Membrane Physiology from the Biophysical Society and Alden Spencer Award for Neuroscience Research from Columbia University.

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Biochemistry and Chemical Biology
    Research focus
    ion channels
    calcium binding proteins
    membrane transport
    allostery and cooperativity
    cellular neurophysiology
    biochemical neuroscience
    Competing interests statement
    Richard Aldrich is employed by The University of Texas at Austin. He receives research funding from the National Institutes of Health. He is a member of the National Academy of Science and the American Academy of Arts and Sciences, and is a Fellow of the American Association for the Advancement of Science and of the Biophysical Society. He serves actively on the editorial boards of Proceedings of the National Academy of Sciences and The Journal of General Physiology.
  3. Philip Cole

    Harvard Medical School, United States

    Phil Cole is Professor of Medicine and Biological Chemistry and Molecular Pharmacology at Harvard Medical School and is a Senior Investigator in the Division of Genetics at Brigham and Women's Hospital. He graduated from Yale University with a B.S. in Chemistry and then spent a year as a Churchill Scholar at the University of Cambridge prior to obtaining M.D. and Ph.D. degrees from Johns Hopkins School of Medicine where he pursued research in bioorganic chemistry. Cole then entered post-doctoral and clinical training at Harvard Medical School and Brigham and Women's Hospital. He subsequently held faculty positions at Rockefeller University and then Johns Hopkins where he was Chair of Pharmacology prior to returning to Harvard in 2017. His research interests are related to the chemical biology of cell signaling and epigenetics. His group has developed and applied methods for protein semisynthesis and small molecule probes for kinases, acyltransferases, deacetylases, and demethylases. His honors include election to the ASCI, fellow of the AAAS, and receipt of an NIH MERIT award.

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    protein modification
    enzyme mechanisms
    cell signalling
    epigenetics
    Competing interests statement
    Philip Cole is on the Scientific Advisory Boards of Memorial Sloan-Kettering Cancer Center, the Maryland Institute of Bioscience and Biotechnology Research, and the Searle Scholars Program. He is a cofounder of Acylin Therapeutics Inc and a science advisor for the Abbvie, Epizyme, and Forma companies and has been a consultant for MPM Capital. Cole has received research funding from the NIH, the FAMRI foundation, and the V Foundation. He is a member of the editorial boards of the following journals: J Biol Chem, Biomed Central Biology, ChemBioChem, and Bioorganic Chemistry.
  4. Volker Dötsch

    Goethe University, Germany

    Volker Dötsch is Professor of Biophysical Chemistry at Goethe University and a member of the Magnetic Resonance Center Frankfurt. He studied chemistry at the University of Göttingen and obtained a PhD from the ETH in Zürich. As a postdoctoral fellow he used NMR to determine the structure of protein-DNA complexes at the Harvard Medical School. In 1998 he moved as assistant professor to the University of California San Francisco (UCSF). In 2003 he was appointed professor at the Institute of Biophysical Chemistry of Goethe University in Frankfurt. His research interests focus on the structural and functional characterization of members of the p53 protein family, in particular p63 and its involvement in genetic quality control in germ cells. In addition, his laboratory uses a combination of NMR spectroscopy and cell-free protein expression to investigate the structure and function of membrane proteins and studies molecular interactions regulating autophagy. His lab uses a wide variety of biophysical methods including NMR spectroscopy and combines these studies with investigations in cell culture experiments and mouse models. Volker Dötsch is an elected EMBO member.

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    p53 protein family
    cell-free expression and membrane protein structure and function
    autophagy
    Competing interests statement
    Volker Dötsch has received funding from the Deutsche Forschungsgemeinschaft, the National Institutes of Health and the Deutsche Krebshilfe. He is on the Scientific Advisory Board of the Frankfurt Institute of Advanced Studies and a member of the editorial boards of Journal of Biological Chemistry and Cell Death & Disease.
  5. José Faraldo-Gómez

    Senior Editor

    José Faraldo-Gómez studied Physics at the Universidad Autónoma in Madrid, Spain, and went on to pursue a PhD degree in the Laboratory of Molecular Biophysics at the University of Oxford, graduating in 2002. He then moved to the United States, and acquired postdoctoral training first at the Weill Medical College of Cornell University in New York City, and subsequently at the University of Chicago. His pre- and post-doctoral work was focused on membrane proteins and in later years also on signaling enzymes, studied through computer simulations and other theoretical methods. In late 2007, Dr Faraldo-Gómez established the Theoretical Molecular Biophysics Laboratory at the Max Planck Institute of Biophysics in Frankfurt, Germany. In 2013, Dr Faraldo-Gómez relocated his laboratory to the National Institutes of Health, in Bethesda, MD, USA, where he joined the National Heart, Lung and Blood Institute as a Tenure-Track Investigator. He became a tenured Senior Investigator in 2016. Dr Faraldo-Gómez served as a handling editor at the Biophysical Journal from 2011 to 2017, and as an Associate Editor in the Journal of General Physiology from 2016 to 2019. At eLife, he first served as a Reviewing Editor, from 2017 to 2019, and is now a Senior Editor.

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    computational biophysics
    molecular computation
    membrane proteins
    Competing interests statement
    José Faraldo-Gómez has no competing interests to disclose. Dr Faraldo-Gómez is a Senior Investigator at the National Heart, Lung and Blood Institute of the US National Institutes of Health.
  6. Vivek Malhotra

    The Barcelona Institute of Science and Technology, Spain

    Vivek Malhotra was a professor in the biology division at UC San Diego from 2007 and is now the ICREA Professor and Chair of the Cell and Developmental Biology at Center for Genomic Regulation (CRG) in Barcelona. His research focuses on a central station of the secretory pathway, the Golgi complex. Specifically, his work has resulted in the identification of the machinery required for the sorting and packaging of secretory cargoes. His recent work has uncovered a novel secretory routing that bypasses the conventional pathway of protein secretion. He has identified new genes required for the export of bulky collagens and the regulated secretion of mucins. He received his BSc from Stirling University and was a Pirie–Reid scholar at Oxford, a Damon Runyon Walter Winchell and an American Cancer Society postdoctoral fellow at Stanford, and Basil O’Conner scholar, established Investigator of the American Heart Association, and Senior Investigator of Sandler’s Foundation for Asthma at UC San Diego. He received the MERCK award from the American Society of Biochemistry and Molecular Biology, is a fellow of the American association of the arts and science, and is an elected EMBO member.

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    Golgi membranes
    protein secretion
    collagen
    mucins
    unconventional protein secretion
    Competing interests statement
    Vivek Malhotra receives funding from ERC/European Research Council, Ministerio de Economía y Competitividad, AGAUR and the Plan Nacional (Spain) He is a Scientific Advisory Board member of TIGEM (Naples, Italy), CNR (Naples, Italy), CBMSO (Madrid, Spain) and Department of Biotechnology (India). He has served on the editorial board of Cell and was an associate editor of Molecular Biology of the Cell. He is currently on the editorial boards of Journal of Cell Biology and Current Opinion in Cell Biology.
  7. Michael Marletta

    University of California, Berkeley, United States

    Michael Marletta holds the CH and Annie Li Chair in the Molecular Biology of Disease and is Professor of Chemistry and of Molecular and Cell Biology at the University of California, Berkeley. Previous to his appointment at UC Berkeley, he was a former President and CEO of The Scripps Research Institute. He has also been on the faculty of the University of Michigan, where he was an HHMI Investigator, and MIT. Marletta obtained an A.B. in chemistry and biology from the State University of New York at Fredonia, a PhD from UCSF under George Kenyon and, after a postdoctoral appointment at MIT under Chris Walsh, began his independent career at MIT. His work has spanned protein chemistry and enzymology. He has made many contributions to our understanding of nitric oxide signaling and more generally in molecular mechanisms of gas sensing in eukaryotes and prokaryotes. More recent studies have involved novel enzymes involved with cellulose degradation. Marletta is a member of the National Academy of Sciences, the National Academy of Medicine, the American Academy of Arts and Sciences and the American Philosophical Society.

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    chemical biology
    nitric oxide signaling
    gas sensing
    structural basis of enzyme activity
    enzymology
    protein structure
    protein function
    metals in biology
    cell signaling
    Experimental organism
    E. coli
    human
    Competing interests statement
    Michael Marletta has received funding from the NIH, NSF, HHMI, and the Burroughs-Wellcome Fund. He is a member of the Biomedical Sciences Advisory Board at Vanderbilt University. He is a member of the Foundation Board at SUNY Fredonia. He is a co-founder of Omniox, Inc. He is a member of the Intelligence Community Studies Board of the National Academies.
  8. Suzanne R Pfeffer

    Stanford University School of Medicine, United States

    Suzanne Pfeffer is the Emma Pfeiffer Merner Professor of Medical Sciences and Professor of Biochemistry at Stanford University School of Medicine. She is an expert in the field of membrane trafficking in the secretory and endocytic pathways, and her research currently focuses on the molecular basis of LRRK2-mediated, familial Parkinson's Disease and Niemann Pick Type C disease, with emphasis on Rab GTPase regulation and cholesterol export from lysosomes. She is a past President of the American Society for Cell Biology and the American Society of Biochemistry and Molecular Biology and a Fellow of the American Society for Cell Biology, the American Association for the Advancement of Science and the American Academy of Arts and Sciences.

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Neuroscience
    Research focus
    membrane trafficking
    endosomes
    lysosomes
    Golgi complex
    neurodegeneration
    Parkinson's disease
    endocytosis
    secretory pathway
    Rab GTPase
    primary cilia
    Experimental organism
    human
    mouse
    Competing interests statement
    Suzanne Pfeffer's research is currently funded by the National Institutes of Health, the Michael J. Fox Foundation and the Ara Parseghian Medical Research Foundation. She serves on the Scientific Advisory Board of the Ara Parseghian Medical Research Foundation, the Swiss National Science Foundation funded NCCR program in Chemical Biology at the EPFL and University of Geneva, and she is a chartered member of the NIH NCSD review panel. Suzanne Pfeffer also serves as Co-Section Head for Membranes and Sorting, Faculty of 1000.
  9. David Ron

    Cambridge University, United Kingdom

    David Ron is a Professor at Cambridge University. He directs a lab at the Cambridge Institute for Medical Research (CIMR) studying protein-folding homeostasis in the endoplasmic reticulum (ER). The lab uses biochemical, biophysical and cell-based tools to research both the molecular mechanisms that recognize the burden of unfolded proteins and thus initiate signalling in the ER unfolded protein response (UPR) and the downstream effector pathways by which cells adapt to unfolded protein stress in their ER. These effector mechanisms engage post-translational regulation of ER chaperone function, regulated translation of mRNA and transcriptional control of gene expression and thus interface with other cellular stress pathways.

    To eLife, David Ron brings scientific expertise in the study of the unfolded protein response, chaperone function and stress-induced regulation of mRNA translation and editorial experience from having served as an eLife Reviewing Editor since 2012.

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    chaperones
    unfolded protein response
    oxidative protein folding
    protein synthesis
    Experimental organism
    C. elegans
    E. coli
    human
    mouse
    S. cerevisiae
    Competing interests statement
    David Ron holds a Wellcome Trust Principal Research Fellowship and is on the editorial advisory boards of J. Cell Science, PLOS Biology and EMBO J.
  10. Dominique Soldati-Favre

    University of Geneva, Switzerland

    Dr Dominique Soldati-Favre studied biochemistry and earned her PhD degree in molecular biology from the University of Zürich (Switzerland) in 1990. She then conducted postdoctoral research in the Department of Microbiology and Immunology of the Stanford University School of Medicine. In 1995 she was appointed assistant professor at the Center for Molecular Biology at the University of Heidelberg (Germany). In 2001 she moved to Imperial College London (United Kingdom) and became Reader. Since 2004, she is professor at the Faculty of Medicine of the University of Geneva.

    Her laboratory is studying obligate intracellular parasitism using Toxoplasma gondii and is also increasingly engaged in malaria research. The main line of research focuses on the cell biology underlying how these pernicious pathogens glide into mammalian cells. Her group is also aiming at defining the metabolic needs and capabilities of the parasites as well as how they subvert host cellular functions in particular to access nutrients.

    Expertise
    Microbiology and Infectious Disease
    Biochemistry and Chemical Biology
    Cell Biology
    Genetics and Genomics
    Research focus
    parasitology
    organelle biogenesis
    protein trafficking
    metabolism
    host pathogen interaction
    signalling
    Experimental organism
    T. gondii
    apicomplexans
    kinetoplastids
    Competing interests statement
    Dominique Soldati-Favre currently receives funding from the European Research Council and from the Swiss National Science Foundation. She is editor for Parasitology at Molecular Microbiology and she is on the editorial boards of PLOS Pathogens, Traffic and mBio.
  11. Kenton J Swartz

    National Institute of Neurological Disorders and Stroke, NIH, United States

    Kenton Swartz has been a Senior Investigator in the National Institute of Neurological Disorders and Stroke within the National Institutes of Health in Bethesda, Maryland since 2003. He obtained a BS in Chemistry and Biology from Eastern Mennonite College in 1986 and a PhD in Neurobiology from Harvard Medical School in 1993, where he worked with Bruce Bean studying the regulation of voltage-gated calcium channels by G-proteins and protein kinases. He obtained postdoctoral training with Roderick MacKinnon at Harvard Medical School, where he began isolating and studying toxins that interact with voltage-activated potassium channels. His laboratory uses biochemical, molecular biological, biophysical and structural techniques to understand how ion channel proteins sense critical biological stimuli, including membrane voltage, temperature, and both chemical and mechanical signals. He received an NIH Directors Award for Scientific Achievement in 2008, an NIH Office of the Director Honor Award on behalf of the Diversity Task Force in 2011 and the Kenneth S. Cole Award from the Biophysical Society in 2017. He has also served as the president of the Society of General Physiologists.

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Biochemistry and Chemical Biology
    Research focus
    ion channel structure
    ion channel mechanisms
    ion channel physiology
    ion channel pharmacology
    Experimental organism
    mouse
    Competing interests statement
    Kenton Swartz is employed by the Intramural Research Program of the National Institute of Neurological Disorders and Stroke, National Institutes of Health. In addition to serving as a Senior Editor at eLife, he has served as a Reviewing Editor for eLife and as an Associate Editor at the Journal of General Physiology. He also teaches yoga at LifeTime Athletic.
  12. Cynthia Wolberger

    Johns Hopkins University School of Medicine, United States

    Cynthia Wolberger is a Professor of Biophysics and Biophysical Chemistry at the Johns Hopkins University School of Medicine, whose faculty she joined in 1991. She received her AB in Physics from Cornell University and her PhD in Biophysics from Harvard University, where she did thesis work on the structural basis of protein-DNA interactions under the guidance of Steve Harrison and Mark Ptashne. After a postdoctoral fellowship at the University of California, San Francisco with Bob Stroud, she worked on the crystal structures of homeodomain-DNA complexes in the laboratory of Carl Pabo at Johns Hopkins. Her earlier worked focused on the structural basis for combinatorial regulation of gene expression and the molecular mechanisms of the sirtuin family of protein deacetylases. Her current research centers on the mechanisms by which ubiquitin plays a signaling role in transcription and the DNA damage response. Wolberger was a recipient of the David and Lucile Packard Fellowship for Science and Engineering, a March of Dimes–Basil O’Conor Starter Scholar Award, and an American Cancer Society Junior Faculty Award, and was a Howard Hughes Medical Institute Investigator from 1994–2014. She received the Protein Society’s Dorothy Crowfoot Hodgkin Award and is a Fellow of the American Association for the Advancement of Science. Dr. Wolberger is a member of the National Academy of Sciences and the American Academy of Arts and Sciences.

    Expertise
    Structural Biology and Molecular Biophysics
    Chromosomes and Gene Expression
    Biochemistry and Chemical Biology
    Research focus
    ubiquitin
    chromatin
    transcription
    post-translational modifications
    histone-modifying enzymes
    Competing interests statement
    Cynthia Wolberger receives funding from the National Institutes of Health , the US–Israel Binational Science Foundation, and the Emerson Collective. She serves on the scientific advisory boards of Thermo Fisher Scientific and the Max Planck Institute for Biochemistry in Martinsried, Germany. She is a member of the Editorial Advisory Board of Protein Science, the Editorial Boards of Structure and Current Opinion in Structural Biology, and is a Faculty of 1000 section head in Transcription and Translation.

Reviewing editors

  1. Jonathan Abraham

    Harvard Medical School, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Microbiology and Infectious Disease
    Medicine
    Research focus
    emerging viruses
    antibody neutralisation
    viral entry
    viral replication
    x-ray crystallography
    cryo-EM
  2. Hossein Ardehali

    Northwestern University, United States

    Expertise
    Medicine
    Biochemistry and Chemical Biology
    Research focus
    mitochondria
    iron
    glucose metabolism
    mRNA-binding proteins
    hexokinases
    metabolism
    cardiac biology
  3. Nir Ben-Tal

    Tel Aviv University, Israel

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Evolutionary Biology
    Structural Biology and Molecular Biophysics
    Research focus
    computational structural biology
    structural biology
    structural bioinformatics
    protein universe
    primordial peptides
    membrane proteins
    transporters
    drug discovery
  4. James Berger

    Johns Hopkins University School of Medicine, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    x-ray crystallography
    electron microscopy
    biochemistry
    biophysics
    DNA replication
    ATPase mechanism
    DNA topology
    topoisomerases
    helicases
    Experimental organism
    B. subtilis
    D. melanogaster
    E. coli
    human
    S. cerevisiae
  5. Douglas L Black

    University of California, Los Angeles, United States

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Research focus
    RNA splicing
    alternative splicing
    RNA binding proteins
    post-transcriptional gene regulation
    neuronal gene expression
    neuronal development
    polypyrimidine tract binding proteins
    Rbfox proteins
    Experimental organism
    mammalian cells
    mouse
    ES cell models
  6. Amie K Boal

    Pennsylvania State University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    bioinorganic chemistry
    enzymes
    microbial chemistry
    x-ray crystallography
  7. Michael R Botchan

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Research focus
    DNA replication
    DNA repair
    Experimental organism
    D. melanogaster
  8. Agnieszka Chacinska

    University of Warsaw, Poland

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    biogenesis
    organelles
    mitochondria
    protein transport
    proteasome
    protein degradation
    protein synthesis
    Experimental organism
    S. cerevisiae
    mammalian cells
    nematode
  9. Pimchai Chaiyen

    Vidyasirimedhi Institute of Science and Technology (VISTEC), Thailand

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    Enzyme
    flavin
    mechanism
    biocatalysis
    metabolic engineering
    bioluminescence
    Experimental organism
    E. coli
    Pseudomonas
  10. Lydia Contreras

    The University of Texas at Austin, United States

    Expertise
    Biochemistry and Chemical Biology
    Microbiology and Infectious Disease
    Research focus
    bacteria
    regulatory RNAs
    sRNAs
    bacterial regulation
    epitranscriptomics
    RNA modifications
  11. Ben Cravatt

    Scripps Research Institute, United States

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    chemical biology
    proteomics
    neurochemistry
    pharmacology
    Experimental organism
    human
    mouse
  12. Qiang Cui

    Boston University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    molecular dynamics
    hybrid quantum
    classical simulations
    enzyme catalysis
    allostery
    protein dynamics
    membrane remodeling
  13. Laura Dassama

    Stanford University, United States

    Expertise
    Biochemistry and Chemical Biology
    Microbiology and Infectious Disease
    Research focus
    bacterial multidrug resistance
    chemoenzymatic syntheses
    beta-hemoglobinopathies
  14. Irwin Davidson

    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Chromosomes and Gene Expression
    Research focus
    transcription
    chromatin
    genomics
    cancer
    Experimental organism
    human
    mouse
  15. Roger J Davis

    University of Massachusetts Medical School, United States

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Cell Biology
    Research focus
    diabetes
    NAFLD
    NASH
    metabolism
    insulin resistance
    cancer
    signal transduction
    Experimental organism
    mouse
    human
  16. Ivan Dikic

    Goethe University Frankfurt, Germany

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    ubiquitination
    autophagy
    bacterial effectors
    Legionella
    ER-phagy
  17. David Drew

    University of Stockholm, Sweden

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    membrane transporters
    x-ray crystallography
    cryo-EM
    membrane protein biotechnology
    bioenergetics
    solute carrier (SLC) transport
  18. Stephen C Ekker

    Mayo Clinic, United States

    Expertise
    Developmental Biology
    Biochemistry and Chemical Biology
    Research focus
    gene editing
    morpholinos
    transposons
    mitochondria
    health engineering
    Experimental organism
    zebrafish
  19. Aaron Frank

    University of Michigan, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    molecular modeling
    biophysics
    structural biology
    computation
    RNA biochemistry
    RNA structural biology
  20. Adam Frost

    University of California, San Francisco, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    cryo-EM
    electron cryo-microscopy
    membranes
    membrane remodeling
    proteostasis
    stress responses
    translation
    mitochondria
    nuclear envelope
    intracellular trafficking
  21. Karine A Gibbs

    Harvard University, United States

    Expertise
    Microbiology and Infectious Disease
    Biochemistry and Chemical Biology
    Research focus
    Proteus mirabilis
    sociomicrobiology
    bacterial genetics
    kin discrimination
    self/non-self recognition
  22. Ruben Gonzalez

    Columbia University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    translation
    translational control
    ribosomes
    RNA
    tRNA
    single-molecule biophysics
    single-molecule fluorescence resonance energy transfer
    cryo-EM
    biochemistry
    live cell imaging
    Experimental organism
    B. subtilis
    E. coli
    human
    S. cerevisiae
  23. Rebekah L. Gundry

    University of Nebraska Medical Center, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Stem Cells and Regenerative Medicine
    Research focus
    mass spectrometry
    cell surface glycoproteins
    proteomics
    glycomics
    heart failure
    stem cell derived cardiomyocytes
    biomarkers
  24. Iqbal Hamza

    University of Maryland, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Genetics and Genomics
    Research focus
    metals
    anemia
    iron
    heme
    Experimental organism
    mouse
    C. elegans
    parasites
  25. Franz-Ulrich Hartl

    Max Planck Institute of Biochemistry, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    protein folding
    molecular chaperones
    neurodegenerative disorders
  26. Heedeok Hong

    Michigan State University, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    membrane proteins
    membrane protein folding
    membrane protein stability
    rhomboid proteases
    ATP-dependent proteolysis
    AAA+
    GlpG
    FtsH
  27. Pankaj Kapahi

    Buck Institute for Research on Aging, United States

    Expertise
    Biochemistry and Chemical Biology
    Developmental Biology
    Research focus
    aging
    age-related diseases
    nutrient signaling
    metabolism
    inflammation
    Experimental organism
    C. elegans
    D. melanogaster
    E. coli
    mouse
  28. Mary B Kennedy

    California Institute of Technology, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Neuroscience
    Research focus
    synaptic plasticity
    synaptic regulation
    biochemical signal transduction networks
    systems biology
    Experimental organism
    mouse
    rat
  29. Daniel J Kliebenstein

    University of California, Davis, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Ecology
    Genetics and Genomics
    Plant Biology
    Research focus
    genetics
    genomics
    transcriptomics
    metabolomics
    pathogen
    plant metabolism
    fitness
    Experimental organism
    A. thaliana
    B. cinerea
    eudicots
  30. Benoît Kornmann

    University of Oxford, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Genetics and Genomics
    Research focus
    membrane contact sites
    mitochondria
    membrane dynamics
    membrane trafficking
    phospholipids
    Experimental organism
    S. cerevisiae
  31. David M Kramer

    Michigan State University, United States

    Expertise
    Biochemistry and Chemical Biology
    Plant Biology
    Physics of Living Systems
    Computational and Systems Biology
    Research focus
    photosynthesis
    bioenergetics
    electron and proton transfer
    computation
    phenotyping
    phenomics
  32. Yamuna Krishnan

    University of Chicago, United States

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    nucleic acid-based molecular devices
    DNA machines
    chemical biology
    synthetic biology
    bioengineering
    Experimental organism
    C. elegans
  33. Andrew C Kruse

    Harvard Medical School, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    signal transduction
    G protein-coupled receptors (GPCR)
    membrane proteins
    x-ray crystallography
    molecular pharmacology
    yeast surface display
  34. Karsten Kruse

    University of Geneva, Switzerland

    Expertise
    Biochemistry and Chemical Biology
    Physics of Living Systems
    Research focus
    cell migration
    cell signalling
    theoretical biology
    molecular evolution
  35. Tatiana G Kutateladze

    University of Colorado School of Medicine, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    epigenetics
    chromatin
    protein structure
    NMR spectroscopy
    molecular mechanisms
    Experimental organism
    human
  36. Ashish Lal

    National Institutes of Health, United States

    Expertise
    Cancer Biology
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    RNA biology
    lncRNAs
    microRNAs
    gene regulation
    cancer biology
    p53
    Experimental organism
    human
  37. Joanne Lemieux

    University of Alberta, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    protease
    intramembrane protease
    crystallography
    membrane proteins
    structural biology
  38. Hening Lin

    Cornell University, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    sirtuin
    PARP
    diphthamide
    post-translational modifications
    proteomics
  39. Sebastian Lourido

    Whitehead Institute for Biomedical Research, United States

    Expertise
    Microbiology and Infectious Disease
    Cell Biology
    Genetics and Genomics
    Biochemistry and Chemical Biology
    Research focus
    calcium signaling
    host-pathogen interactions
    genetic screening
    protein kinases
    genomics
    quantitative proteomics
    Apicomplexan parasites
    Experimental organism
    T. gondii
    P. falciparum
  40. Andrei Lupas

    Max Planck Institute for Developmental Biology, Germany

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Structural Biology and Molecular Biophysics
    Evolutionary Biology
    Research focus
    bacterial surface proteins
    bioinformatics
    coiled coils
    protein design
    protein evolution
    protein structure
    transmembrane signal tranduction
  41. Koyeli Mapa

    Shiv Nadar University, India

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    proteostasis
    chaperones
    stress response
    unfolded protein response
    heat shock proteins
    mitochondria
    protein folding
    Experimental organism
    yeast
    human cells
    E. coli
  42. Andreas Martin

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    AAA+ ATPases
    protein degradation
    proteostasis
    ATPase mechanism
    protein folding
  43. Malcolm J McConville

    University of Melbourne, Australia

    Expertise
    Microbiology and Infectious Disease
    Biochemistry and Chemical Biology
    Research focus
    protozoan parasites
    metabolomics
    metabolism
    Leishmaniasis
    trypanosomatids
    glycobiology
    Experimental organism
    T. gondii
  44. Hitoshi Nakatogawa

    Tokyo Institute of Technology, Japan

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Research focus
    molecular mechanisms of autophagy
    protein/organelle degradation
    membrane dynamics
    Experimental organism
    S. cerevisiae
  45. Geeta Narlikar

    University of California, San Francisco, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    chromatin
    heterochromatin spread
    chromatin remodeling machines
    phase-separation
  46. Hannes Neuweiler

    University of Würzburg, Germany

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    protein folding
    protein dynamics
    protein engineering
    fluorescence spectroscopy
    fluorescence probes
    kinetics
    single-molecule fluorescence spectroscopy
  47. Timothy Nilsen

    Case Western Reserve University, United States

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Research focus
    mRNA processing
    mechanism of miRNA function
    RNA protein interactions
    mRNP composition and function
    RNA biology
    Experimental organism
    D. melanogaster
  48. Kassandra Ori-McKenney

    University of California , United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Neuroscience
    Research focus
    microtubules
    microtubule-associated proteins
    microtubule motors
    tau neurofibrillary tangles
    neurodegeneration
    Experimental organism
    D. melanogaster
    mammalian cell culture
  49. Kim Orth

    University of Texas Southwestern Medical Center, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Microbiology and Infectious Disease
    Research focus
    Vibrio
    T3SS
    virulence pathogenesis
    host-pathogen
    AMPylation
    Fic-domain
    Experimental organism
    Vibrio spp
  50. Rohit V Pappu

    Washington University in St Louis, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    biophysics
    intrinsically disordered proteins
    intracellular phase transition phenomena
    organization of proteins and nucleic acids
  51. Maddy Parsons

    King's College London, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Cell Biology
    Physics of Living Systems
    Research focus
    adhesion
    migration
    cytoskeleton
    receptor signalling
    extracellular matrix
    fibrosis
    cancer
    Experimental organism
    mouse
  52. Federico Pelisch

    University of Dundee, United Kingdom

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Research focus
    meiosis
    SUMO
    phosphorylation
    ubiquitin
    oocytes
    chromosome segregation
    Experimental organism
    C. elegans
  53. Jon Pines

    Institute of Cancer Research, University College London, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    cyclins and anaphase promoting complex/cycosome (APC/C)
    cell cycle
    mitosis
    spindle assembly checkpoint
    Experimental organism
    human
  54. Stephan Pless

    University of Copenhagen, Denmark

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    ion channels
    pharmacology
    electrophysiology
    biophysics
    chemical biology
    non-canonical amino acids
    protein engineering
    neurobiology
  55. Arun Radhakrishnan

    University of Texas Southwestern Medical Center, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    lipid sensors
    cholesterol
    sphingomyelin
    cholesterol transport
    SREBP
    Scap
    cholesterol homeostasis
    endoplasmic reticulum
    Experimental organism
    E. coli
    human
    mouse
  56. Michael Rape

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Developmental Biology
    Research focus
    ubiquitin
    quality control
    protein aggregation
    mitochondria
    proteasome
    Experimental organism
    human
    mouse
  57. Frank Raushel

    Texas A&M University, United States

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    bioorganic chemistry
    enzyme catalysis
    chemical biology
    enzyme engineering
  58. Janice L Robertson

    Washington University in St. Louis, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Computational and Systems Biology
    Physics of Living Systems
    Biochemistry and Chemical Biology
    Research focus
    membrane protein folding
    computational modeling
    oligomerization
    membrane transport
    driving forces
    lipids
  59. Rajan Sankaranarayanan

    CSIR – Centre for Cellular and Molecular Biology, India

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    crystal structure
    mechanism
    translation of genetic code
    proofreading
    editing
    tRNA synthetase
    Experimental organism
    E. coli
  60. Tricia Serio

    The University of Massachusetts, Amherst, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    protein folding/misfolding
    prions
    chaperones
    protein homeostasis
    protein quality control
    amyloid
    Experimental organism
    S. cerevisiae
  61. Nima Sharifi

    Cleveland Clinic, United States

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Medicine
    Research focus
    steroid biochemistry
    steroid metabolism
    prostate cancer
    nuclear receptors
    hormone therapy resistance
    androgens
    oncology
    Experimental organism
    mouse
  62. Akira Shinohara

    Osaka University, Japan

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Cell Biology
    Research focus
    recombination
    DSB repair
    meiosis
    chromosome
    DNA damage response
    Experimental organism
    S. cerevisiae
    human
    mouse
  63. Gustavo Monteiro Silva

    Duke University, United States

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    ubiquitin
    oxidative stress
    translation
    proteomics
    Experimental organism
    human
    mouse
    S. cerevisiae
  64. Maria Spies

    University of Iowa, United States

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Chromosomes and Gene Expression
    Structural Biology and Molecular Biophysics
    Research focus
    single-molecule biophysics
    DNA repair
    DNA replication
    DNA recombination
    genome stability
    protein dynamics
    protein-nucleic acids interactions
    drug discovery
    Experimental organism
    human
    yeast
    bacteria
  65. Jonathan P Staley

    University of Chicago, United States

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    splicing
    spliceosome
    intron
    exon
    splice site
    co-transcriptional
    Experimental organism
    budding yeast
    mammalian cell culture
  66. Randy B Stockbridge

    University of Michigan, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    ion channels
    transporters
    microbial membrane proteins
    crystallography
    electrophysiology
    Experimental organism
    E. coli
  67. Thomas Surrey

    The Francis Crick Institute, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    cytoskeleton
    spindle assembly
    cell division
    motor proteins
    microtubules
    self-organization
    active networks
    Experimental organism
    human
  68. Ivan Topisirovic

    Jewish General Hospital, Canada

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Cell Biology
    Research focus
    mRNA translation
    signaling
    metabolic regulation
    protein quality control
    Experimental organism
    mouse
    human
  69. Eric J Wagner

    University of Texas Medical Branch at Galveston, United States

    Expertise
    Chromosomes and Gene Expression
    Biochemistry and Chemical Biology
    Cancer Biology
    Genetics and Genomics
    Research focus
    RNA biology
    transcription
    RNA processing
    gene expression
  70. Oliver Weichenrieder

    Max Planck Institute for Developmental Biology, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Genetics and Genomics
    Research focus
    retrotransposition
    regulatory mRNA
    x-ray crystallography
    structural biology
  71. William I Weis

    Stanford University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    cell adhesion
    wnt signaling
    X-ray crystallography
    structural biology
    Experimental organism
    C. elegans
    Dictyostelium
    human
    mouse
  72. Julie P I Welburn

    University of Edinburgh, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    mitosis
    cytoskeleton
    motors
    phosphorylation
    kinase
    microtubule
    cilia
    kinetochore
    Experimental organism
    human
    in vitro
  73. Raymund Wellinger

    Université de Sherbrooke, Canada

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    chromosome biology
    DNA replication
    telomeres
    telomerase
    yeast cell biology
    Experimental organism
    yeast
    mouse
  74. Jie Xiao

    Johns Hopkins University, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Chromosomes and Gene Expression
    Microbiology and Infectious Disease
    Physics of Living Systems
    Structural Biology and Molecular Biophysics
    Research focus
    single molecule biophysics
    microbiology
    cell division
    cell wall
    gene expression
    Experimental organism
    E. coli
  75. Gary Yellen

    Harvard Medical School, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Physics of Living Systems
    Research focus
    neuronal metabolism
    control of energy metabolism
    fluorescent biosensors
    metabolic control of excitability
    Experimental organism
    mouse
  76. Ahmet Yildiz

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Physics of Living Systems
    Research focus
    dynein
    kinesin
    myosin
    intraflagellar transport
    Experimental organism
    human
    yeast
    Chlamydomonas
  77. Giulia Zanetti

    Birkbeck, University of London, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    membrane trafficking
    coat proteins
    COPII
    membrane remodeling
    structural biology
    cryo-EM
    cryo-ET
    subtomogram averaging
    Experimental organism
    S. cerevisiae
  78. Mingjie Zhang

    Hong Kong University of Science and Technology, Hong Kong SAR China

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    postsynaptic density
    synaptic signaling
    scaffold proteins
    liquid-liquid phase separation
    biological condensates