Editors for Biochemistry and Chemical Biology
Senior editors
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Amy H Andreotti
Iowa State University, United States
Amy Andreotti is the Roy J Carver Chair in Biochemistry and a University Professor at Iowa State University. She joined the faculty of the Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology in 1997 after earning her PhD in Chemistry at Princeton University and completing a postdoctoral training period in the Chemistry Department at Harvard University where she was a Science Scholar at the Bunting Institute of Radcliffe College. Her work explores the mechanisms of kinase regulation during cell signaling with an emphasis on the immune specific TEC family of non-receptor tyrosine kinases. A particular focus of the lab is Bruton’s tyrosine kinase (BTK) and its interactions with small molecule therapeutics. Her lab uses a variety of biochemical, enzymatic and structural biology methods including solution NMR spectroscopy.
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- NMR spectroscopy
- kinase regulation
- cell signalling
- Tec family kinases
- Experimental organism
- human
- Competing interests statement
- Amy Andreotti's research is currently funded by the National Institutes of Health. She also serves on the National Advisory Committee for the Biomedical Scholars program of the Pew Charitable Trusts.
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Nancy Carrasco
Vanderbilt University School of Medicine, United States
Nancy Carrasco is the Joe C. Davis Professor and Chair of the Department of Molecular Physiology and Biophysics at the Vanderbilt University School of Medicine. She obtained her MD and Master’s in Biochemistry from the National Autonomous University of Mexico in her native Mexico City. Dr Carrasco did her postdoctoral work at the Roche Institute of Molecular Biology in New Jersey, for which she received a Fogarty International Fellowship. She then joined the Department of Molecular Pharmacology at the Albert Einstein College of Medicine, and later the Department of Cellular and Molecular Physiology at the Yale School of Medicine. Dr Carrasco has a longstanding interest in transport across biological membranes and in the role of membrane proteins in physiology and pathophysiology. Her cloning of the sodium/iodide symporter (NIS) has had numerous ramifications for many other fields, including structure/function of transport proteins, molecular endocrinology, gene transfer studies, cancer, and public health (she has served on the EPA’s Science Advisory Board). She has received numerous awards, including the Pew Award; the Arnold and Mabel Beckman Foundation Award; the Maria Sibylla Merian Award (Germany); the Merck Prize from the European Thyroid Association (Poland); the Rose Pitt-Rivers Lectureship at the British Endocrine Society Meeting (Scotland); the Noun Shavit Award (Israel); the Marshall S. Horwitz Faculty Prize for Research Excellence; and the Light of Life Award. She has served as president of the Society of Latin American Biophysicists. Dr Carrasco was elected to the National Academy of Sciences in 2015 and to the National Academy of Medicine in 2020.
- Expertise
- Medicine
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular endocrinology
- biochemistry of membrane proteins
- biophysics of membrane proteins
- mechanistic information of NIS
- regulation of NIS
- sodium/iodide symporter
- cross-talk between hormones
- metabolism
- Experimental organism
- mouse
- human
- Competing interests statement
- Dr Carrasco’s research has been funded by NIH. She is on the NICHD Board of Scientific Counselors.
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Qiang Cui
Boston University, United States
Qiang Cui is a professor of Chemistry at Boston University and also affiliated with the Departments of Physics and Biomedical Engineering. He received a B.S. in Chemical Physics from the University of Science and Technology of China in 1993, and a Ph.D. in Theoretical Chemistry in 1997 from Emory University under the tutelage of Professor Keiji Morokuma. He conducted postodctoral research with Professor Martin Karplus at Harvard University and, in 2001, moved to the University of Wisconsin, Madison, as a faculty member in the Chemistry department. After spending almost 17 wonderful years in Madison, he moved back to Boston in 2018. His current research interests include quantum chemistry and statistical mechanics and their applications to various chemical, biological, and materials problems.
Expertise: Computational biophysics, especially molecular dynamics, hybrid quantum mechanical/molecular mechanics simulations, free energy simulations applied to enzymes, biomolecular machines and lipid membranes.
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular dynamics
- hybrid quantum
- classical simulations
- enzyme catalysis
- allostery
- protein dynamics
- membrane remodeling
- Competing interests statement
- Qiang Cui currently serves as an associate editor for the Journal of Chemical Theory and Computation (American Chemical Society).
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Volker Dötsch
Goethe University, Germany
Volker Dötsch is Professor of Biophysical Chemistry at Goethe University and a member of the Magnetic Resonance Center Frankfurt. He studied chemistry at the University of Göttingen and obtained a PhD from the ETH in Zürich. As a postdoctoral fellow he used NMR to determine the structure of protein-DNA complexes at the Harvard Medical School. In 1998 he moved as assistant professor to the University of California San Francisco (UCSF). In 2003 he was appointed professor at the Institute of Biophysical Chemistry of Goethe University in Frankfurt. His research interests focus on the structural and functional characterization of members of the p53 protein family, in particular p63 and its involvement in genetic quality control in germ cells. In addition, his laboratory uses a combination of NMR spectroscopy and cell-free protein expression to investigate the structure and function of membrane proteins and studies molecular interactions regulating autophagy. His lab uses a wide variety of biophysical methods including NMR spectroscopy and combines these studies with investigations in cell culture experiments and mouse models. Volker Dötsch is an elected EMBO member.
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- p53 protein family
- cell-free expression and membrane protein structure and function
- autophagy
- Competing interests statement
- Volker Dötsch has received funding from the Deutsche Forschungsgemeinschaft, the National Institutes of Health and the Deutsche Krebshilfe. He is on the Scientific Advisory Board of the Frankfurt Institute of Advanced Studies and a member of the editorial boards of Journal of Biological Chemistry and Cell Death & Disease.
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David James
University of Sydney, Australia
Professor James currently holds the Leonard P Ullmann Chair in Molecular Systems Biology and he is the Domain Leader for Biology at the Charles Perkins Centre, University of Sydney. Professor James has made major contributions to our understanding of insulin action. In the late 1980s he published a series of journal articles in Nature describing the identification and characterization of the insulin responsive glucose transporter GLUT4. Professor James then focused his efforts on unveiling the cellular and molecular control of insulin-stimulated glucose transport. He has also made contributions in the area of SNARE proteins, signal transduction and more recently in systems biology.
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- diabetes
- signal transduction
- systems biology
- Experimental organism
- mouse
- human
- rat
- Competing interests statement
- David James has been funded by bodies like National Health and Medical Research Council (NHMRC), Wellcome Trust, Australian Research Council (ARC), NIH, Pfizer, Eli Lilly and Novo, had continuous NHMRC research fellowships since 1998 and is now Senior Principal Research Fellow.
James has served on editorial boards of journals such as The Journal of Biological Chemistry and The American Journal of Physiology for more than 10 years and is currently on five boards with major roles at Cell Metabolism (only Australian) and The Journal of Clinical Investigation. James reviews ~30 manuscripts per year for journals like Nature, Nature Cell Biology, Nature Medicine, Science, PNAS, The Journal Clinical Invest, Molecular Endocrinology, Endocrinology, Molecular Biology of the Cell, Journal of Cell Biology, Traffic, FASEB J, Genes & Development and grants for Diabetes Australia, National Heart, Wellcome Trust, ARC, NHMRC and International Foundations.
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Benoît Kornmann
University of Oxford, United Kingdom
Benoit Kornmann is Associate Professor at the Department of Biochemistry, University of Oxford, and fellow of St Hugh’s College. Benoit Kornmann studies membrane contact sites, how intracellular organization impinges on organelle function and how lipid molecules are distributed among the many membranes of a eukaryotic cell. Benoit Kornmann is an expert in yeast genetics, membrane biology, organelle dynamics and signalling. He holds a PhD of the University of Geneva, and previously held the positions of Assistant Professor at the ETH Zurich, Professor of the Swiss National Science Foundation, and fellow of the Swiss National Science Foundation.
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Genetics and Genomics
- Research focus
- membrane contact sites
- mitochondria
- membrane dynamics
- membrane trafficking
- phospholipids
- Experimental organism
- S. cerevisiae
- Competing interests statement
- Benoit Kornmann is funded by the Wellcome trust and Syngenta Crop Protection. He is a board member of Review Commons and Contact, a faculty member of Faculty Opinions, and an advisory board member of F1000 Research.
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Merritt Maduke
Stanford University School of Medicine, United States
Merritt Maduke is an Associate Professor of Molecular & Cellular Physiology and co-director of the Neurosciences Interdisciplinary Graduate Program at Stanford University School of Medicine. She received her PhD in Chemistry from the University of California, San Diego and did postdoctoral training at Brandeis University with Professor Chris Miller. Her research at Stanford is centered on the biophysics of ion channels and transporters, with the overarching goal of understanding molecular mechanisms within the context of physiological functions. She also applies her mechanistic approach in the field of ultrasound neuromodulation. She was awarded the Society of General Physiologist’s Cranefield Award for her research on ion channels (2008) and served as the Society’s President from 2018-2019.
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Biochemistry and Chemical Biology
- Research focus
- ion channel and transporter molecular mechanisms
- ion channel and transporter physiology
- ion channel and transporter pharmacology
- ultrasound neuromodulation
- Experimental organism
- E. coli
- mouse
- rat
- Competing interests statement
- Merritt Maduke is employed by Stanford University and receives research funding from the National Institutes of Health and Stanford Innovative Medicine Accelerator. She has served on the BPNS and BBM study sections at the NIH and as ad hoc member of additional panels. She serves on the editorial boards of the Biophysical Journal and The Journal of General Physiology and is a founding curator for Biophysics Colab.
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David Ron
Cambridge University, United Kingdom
David Ron is a Professor at Cambridge University. He directs a lab at the Cambridge Institute for Medical Research (CIMR) studying protein-folding homeostasis in the endoplasmic reticulum (ER). The lab uses biochemical, biophysical and cell-based tools to research both the molecular mechanisms that recognize the burden of unfolded proteins and thus initiate signalling in the ER unfolded protein response (UPR) and the downstream effector pathways by which cells adapt to unfolded protein stress in their ER. These effector mechanisms engage post-translational regulation of ER chaperone function, regulated translation of mRNA and transcriptional control of gene expression and thus interface with other cellular stress pathways.
To eLife, David Ron brings scientific expertise in the study of the unfolded protein response, chaperone function and stress-induced regulation of mRNA translation and editorial experience from having served as an eLife Reviewing Editor since 2012.
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- chaperones
- unfolded protein response
- oxidative protein folding
- protein synthesis
- Experimental organism
- C. elegans
- E. coli
- human
- mouse
- S. cerevisiae
- Competing interests statement
- David Ron holds a Wellcome Trust Principal Research Fellowship and is on the editorial advisory boards of J. Cell Science, PLOS Biology and EMBO J.
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Dominique Soldati-Favre
University of Geneva, Switzerland
Dr Dominique Soldati-Favre studied biochemistry and earned her PhD degree in molecular biology from the University of Zürich (Switzerland). She is full Professor at the department of Microbiology and Molecular Medicine at the Faculty of Medicine of the University of Geneva. Her laboratory is studying obligate intracellular parasitism using Toxoplasma gondii. The main line of research focuses on the cell biology underlying parasite active invasion into mammalian cells. Her group is also aiming at defining the metabolic needs and capabilities of the parasites as well as how they subvert host cellular functions notably to access nutrients.
- Expertise
- Microbiology and Infectious Disease
- Biochemistry and Chemical Biology
- Cell Biology
- Genetics and Genomics
- Research focus
- parasitology
- organelle biogenesis
- protein trafficking
- metabolism
- host pathogen interaction
- signalling
- Experimental organism
- T. gondii
- apicomplexans
- kinetoplastids
- Competing interests statement
- Dominique Soldati-Favre’s research is currently funded by the Swiss National Science Foundation. She serves as Section Editor at PLOS Pathogens, and Editor at mBio.
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Kenton J Swartz
National Institute of Neurological Disorders and Stroke, NIH, United States
Kenton Swartz has been a Senior Investigator in the National Institute of Neurological Disorders and Stroke within the National Institutes of Health in Bethesda, Maryland since 2003. He obtained a BS in Chemistry and Biology from Eastern Mennonite College in 1986 and a PhD in Neurobiology from Harvard Medical School in 1993, where he worked with Bruce Bean studying the regulation of voltage-gated calcium channels by G-proteins and protein kinases. He obtained postdoctoral training with Roderick MacKinnon at Harvard Medical School, where he began isolating and studying toxins that interact with voltage-activated potassium channels. His laboratory uses biochemical, molecular biological, biophysical and structural techniques to understand how ion channel proteins sense critical biological stimuli, including membrane voltage, temperature, and both chemical and mechanical signals. He received an NIH Directors Award for Scientific Achievement in 2008, an NIH Office of the Director Honor Award on behalf of the Diversity Task Force in 2011 and the Kenneth S. Cole Award from the Biophysical Society in 2017. He has also served as the president of the Society of General Physiologists.
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Biochemistry and Chemical Biology
- Research focus
- ion channel structure
- ion channel mechanisms
- ion channel physiology
- ion channel pharmacology
- Experimental organism
- mouse
- Competing interests statement
- Kenton Swartz is employed by the Intramural Research Program of the National Institute of Neurological Disorders and Stroke, National Institutes of Health. In addition to serving as a Senior Editor at eLife, he has served as a Reviewing Editor for eLife and as an Associate Editor at the Journal of General Physiology. He also teaches yoga at LifeTime Athletic.
Reviewing editors
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Fernán Agüero
Universidad Nacional de San Martín, Argentina
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Computational and Systems Biology
- Evolutionary Biology
- Genetics and Genomics
- Immunology and Inflammation
- Microbiology and Infectious Disease
- Research focus
- genomics
- drug discovery
- diagnostics
- infectious diseases
- microbial eukaryotes
- bioinformatics
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Caetano Antunes
University of Kansas, United States
- Expertise
- Biochemistry and Chemical Biology
- Genetics and Genomics
- Microbiology and Infectious Disease
- Research focus
- microbiome
- host-microbe interactions
- metabolomics
- gene regulation
- microbial signaling
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Demet Araç
University of Chicago, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- G protein-coupled receptors (GPCR)
- synapse formation
- cell adhesion
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Hossein Ardehali
Northwestern University, United States
- Expertise
- Medicine
- Biochemistry and Chemical Biology
- Research focus
- mitochondria
- iron
- glucose metabolism
- mRNA-binding proteins
- hexokinases
- metabolism
- cardiac biology
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Muthuswamy Balasubramanyam
ICMR Emeritus Scientist, Madras Diabetes Research Foundation, India
- Expertise
- Medicine
- Biochemistry and Chemical Biology
- Cancer Biology
- Cell Biology
- Developmental Biology
- Epidemiology and Global Health
- Genetics and Genomics
- Immunology and Inflammation
- Neuroscience
- Stem Cells and Regenerative Medicine
- Research focus
- disease biology
- diabetes
- aging
- omnics
- calcium signaling
- endocrine disruptors
- probiotics
- molecular medicine
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Anton M Bennett
Yale University, United States
- Expertise
- Cell Biology
- Biochemistry and Chemical Biology
- Cancer Biology
- Research focus
- cell signalling
- metabolism
- protein tyrosine phosphorylation
- protein tyrosine kinases
- protein tyrosine phosphatases
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Amie K Boal
Pennsylvania State University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- bioinorganic chemistry
- enzymes
- microbial chemistry
- x-ray crystallography
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Michael R Botchan
University of California, Berkeley, United States
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Research focus
- DNA replication
- DNA repair
- Experimental organism
- D. melanogaster
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Paula Casati
Center of Photosynthetic And Biochemical Studies (CEFOBI), Argentina
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Plant Biology
- Research focus
- genome stability
- abiotic stress in plants
- chromatin remodelling
- cell cycle regulation
- flavonoid metabolism
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Agnieszka Chacinska
University of Warsaw, Poland
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- biogenesis
- organelles
- mitochondria
- protein transport
- proteasome
- protein degradation
- protein synthesis
- Experimental organism
- S. cerevisiae
- mammalian cells
- nematode
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Laura Dassama
Stanford University, United States
- Expertise
- Biochemistry and Chemical Biology
- Microbiology and Infectious Disease
- Research focus
- bacterial multidrug resistance
- chemoenzymatic syntheses
- beta-hemoglobinopathies
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Irwin Davidson
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Chromosomes and Gene Expression
- Research focus
- transcription
- chromatin
- genomics
- cancer
- Experimental organism
- human
- mouse
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Roger J Davis
University of Massachusetts Medical School, United States
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Cell Biology
- Research focus
- diabetes
- NAFLD
- NASH
- metabolism
- insulin resistance
- cancer
- signal transduction
- Experimental organism
- mouse
- human
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Gina M DeNicola
Moffitt Cancer Center, United States
- Expertise
- Cancer Biology
- Biochemistry and Chemical Biology
- Research focus
- tumor metabolism
- redox biology
- ROS
- sulfur metabolism
- NRF2/KEAP1
- mouse models of cancer
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Martin S Denzel
Altos Labs, Cambridge Institute of Science, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Genetics and Genomics
- Research focus
- aging
- metabolism
- protein homeostasis
- cell culture
- Experimental organism
- C. elegans
- mouse
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David Drew
University of Stockholm, Sweden
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- membrane transporters
- x-ray crystallography
- cryo-EM
- membrane protein biotechnology
- bioenergetics
- solute carrier (SLC) transport
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Stephen C Ekker
Mayo Clinic, United States
- Expertise
- Developmental Biology
- Biochemistry and Chemical Biology
- Research focus
- gene editing
- morpholinos
- transposons
- mitochondria
- health engineering
- Experimental organism
- zebrafish
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Aaron Frank
Arrakis Therapeutics, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- molecular modeling
- biophysics
- structural biology
- computation
- RNA biochemistry
- RNA structural biology
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Adam Frost
University of California, San Francisco, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- cryo-EM
- electron cryo-microscopy
- membranes
- membrane remodeling
- proteostasis
- stress responses
- translation
- mitochondria
- nuclear envelope
- intracellular trafficking
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Mari Gantner
The Lowy Medical Research Institute, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Medicine
- Research focus
- retinal disease
- retinal metabolism
- patient metabolomics
- amino acid metabolism
- sphingolipid biology
- Retinal pigment epithelium (RPE) biology
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Ilias Georgakopoulos-Soares
Pennsylvania State University, United States
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- gene regulation
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Karine A Gibbs
Harvard University, United States
- Expertise
- Microbiology and Infectious Disease
- Biochemistry and Chemical Biology
- Research focus
- Proteus mirabilis
- sociomicrobiology
- bacterial genetics
- kin discrimination
- self/non-self recognition
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Gustavo H Goldman
Universidade de Sao Paulo, Brazil
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Chromosomes and Gene Expression
- Genetics and Genomics
- Microbiology and Infectious Disease
- Research focus
- filamentous fungi
- Aspergillus
- secondary metabolites
- gene expression
- molecular biology
- infectious diseases
- drug tolerance
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Ruben Gonzalez
Columbia University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- translation
- translational control
- ribosomes
- RNA
- tRNA
- single-molecule biophysics
- single-molecule fluorescence resonance energy transfer
- cryo-EM
- biochemistry
- live cell imaging
- Experimental organism
- B. subtilis
- E. coli
- human
- S. cerevisiae
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Martin Graña
Institut Pasteur de Montevideo, Uruguay
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Evolutionary Biology
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- protein 3D structure
- structural bioinformatics
- structure/function relationships
- evolution
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Rebekah L. Gundry
University of Nebraska Medical Center, United States
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Stem Cells and Regenerative Medicine
- Research focus
- mass spectrometry
- cell surface glycoproteins
- proteomics
- glycomics
- heart failure
- stem cell derived cardiomyocytes
- biomarkers
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Iqbal Hamza
University of Maryland, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Genetics and Genomics
- Research focus
- metals
- anemia
- iron
- heme
- Experimental organism
- mouse
- C. elegans
- parasites
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Franz-Ulrich Hartl
Max Planck Institute of Biochemistry, Germany
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protein folding
- molecular chaperones
- neurodegenerative disorders
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Heedeok Hong
Michigan State University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- membrane proteins
- membrane protein folding
- membrane protein stability
- rhomboid proteases
- ATP-dependent proteolysis
- AAA+
- GlpG
- FtsH
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Pankaj Kapahi
Buck Institute for Research on Aging, United States
- Expertise
- Biochemistry and Chemical Biology
- Developmental Biology
- Research focus
- aging
- age-related diseases
- nutrient signaling
- metabolism
- inflammation
- Experimental organism
- C. elegans
- D. melanogaster
- E. coli
- mouse
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Mary B Kennedy
California Institute of Technology, United States
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Neuroscience
- Research focus
- synaptic plasticity
- synaptic regulation
- biochemical signal transduction networks
- systems biology
- Experimental organism
- mouse
- rat
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David M Kramer
Michigan State University, United States
- Expertise
- Biochemistry and Chemical Biology
- Plant Biology
- Physics of Living Systems
- Computational and Systems Biology
- Research focus
- photosynthesis
- bioenergetics
- electron and proton transfer
- computation
- phenotyping
- phenomics
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Yamuna Krishnan
University of Chicago, United States
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- nucleic acid-based molecular devices
- DNA machines
- chemical biology
- synthetic biology
- bioengineering
- Experimental organism
- C. elegans
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Karsten Kruse
University of Geneva, Switzerland
- Expertise
- Biochemistry and Chemical Biology
- Physics of Living Systems
- Research focus
- cell migration
- cell signalling
- theoretical biology
- molecular evolution
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Tapas K Kundu
Jawaharlal Nehru Centre for Advanced Scientific Research, India
- Expertise
- Cancer Biology
- Chromosomes and Gene Expression
- Biochemistry and Chemical Biology
- Research focus
- epigenetics
- chromatin organization
- nonhistone chromatin proteins
- epigenetic regulation of diseases
- eukaryotic transcription regulation
- small molecule modulators of epigenetic enzymes
- Experimental organism
- human
- mouse
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Tatiana G Kutateladze
University of Colorado School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- epigenetics
- chromatin
- protein structure
- NMR spectroscopy
- molecular mechanisms
- Experimental organism
- human
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Ashish Lal
National Institutes of Health, United States
- Expertise
- Cancer Biology
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Genetics and Genomics
- Research focus
- RNA biology
- lncRNAs
- microRNAs
- gene regulation
- cancer biology
- p53
- Experimental organism
- human
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Joanne Lemieux
University of Alberta, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protease
- intramembrane protease
- crystallography
- membrane proteins
- structural biology
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Hongliang Li
Wuhan University School of Medicine, China
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Epidemiology and Global Health
- Immunology and Inflammation
- Medicine
- Research focus
- cardiometabolic disease
- metabolic disease
- vascular injury
- animal models
- liver
- innate immunity
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Sebastian Lourido
Whitehead Institute for Biomedical Research, United States
- Expertise
- Microbiology and Infectious Disease
- Cell Biology
- Genetics and Genomics
- Biochemistry and Chemical Biology
- Research focus
- calcium signaling
- host-pathogen interactions
- genetic screening
- protein kinases
- genomics
- quantitative proteomics
- Apicomplexan parasites
- Experimental organism
- T. gondii
- P. falciparum
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Kristen W Lynch
University of Pennsylvania, United States
- Expertise
- Chromosomes and Gene Expression
- Biochemistry and Chemical Biology
- Genetics and Genomics
- Research focus
- RNA
- post-transcriptional gene regulation
- RNA silencing
- RNA binding proteins
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Koyeli Mapa
Shiv Nadar University, India
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- proteostasis
- chaperones
- stress response
- unfolded protein response
- heat shock proteins
- mitochondria
- protein folding
- Experimental organism
- yeast
- human cells
- E. coli
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Malcolm J McConville
University of Melbourne, Australia
- Expertise
- Microbiology and Infectious Disease
- Biochemistry and Chemical Biology
- Research focus
- protozoan parasites
- metabolomics
- metabolism
- Leishmaniasis
- trypanosomatids
- glycobiology
- Experimental organism
- T. gondii
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Marcelo A Mori
State University of Campinas, Brazil
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Chromosomes and Gene Expression
- Genetics and Genomics
- Immunology and Inflammation
- Research focus
- aging
- metabolism
- obesity
- adipose tissue
- microRNAs
- endocrinology
- integrative physiology
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Hitoshi Nakatogawa
Tokyo Institute of Technology, Japan
- Expertise
- Cell Biology
- Biochemistry and Chemical Biology
- Research focus
- molecular mechanisms of autophagy
- protein/organelle degradation
- membrane dynamics
- Experimental organism
- S. cerevisiae
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P Darrell Neufer
East Carolina University, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Medicine
- Research focus
- metabolic disease
- mitochondrial bioenergetics
- cellular bioenergetics
- mitochondrial biogenesis and exercise
- Experimental organism
- human
- flies
- rat
- mouse
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Hannes Neuweiler
University of Würzburg, Germany
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- protein folding
- protein dynamics
- protein engineering
- fluorescence spectroscopy
- fluorescence probes
- kinetics
- single-molecule fluorescence spectroscopy
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Kassandra Ori-McKenney
University of California , United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Neuroscience
- Research focus
- microtubules
- microtubule-associated proteins
- microtubule motors
- tau neurofibrillary tangles
- neurodegeneration
- Experimental organism
- D. melanogaster
- mammalian cell culture
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Akhilesh Pandey
Mayo Clinic, United States
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Research focus
- proteomics
- quantitative proteomics
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Benjamin L Parker
University of Melbourne, Australia
- Expertise
- Cell Biology
- Computational and Systems Biology
- Biochemistry and Chemical Biology
- Research focus
- proteomics
- signal transduction
- metabolism
- skeletal muscle
- exercise
- insulin resistance
- phosphorylation
- protein post-translational modifications
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Jon Pines
Institute of Cancer Research, University College London, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- cyclins and anaphase promoting complex/cycosome (APC/C)
- cell cycle
- mitosis
- spindle assembly checkpoint
- Experimental organism
- human
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Stephan Pless
University of Copenhagen, Denmark
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- ion channels
- pharmacology
- electrophysiology
- biophysics
- chemical biology
- non-canonical amino acids
- protein engineering
- neurobiology
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Owen Pornillos
University of Virginia, United States
- Expertise
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- higher-order assembly
- cell-free reconstitution
- retrovirus structure
- tripartite motif proteins
-
Arun Radhakrishnan
University of Texas Southwestern Medical Center, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- lipid sensors
- cholesterol
- sphingomyelin
- cholesterol transport
- SREBP
- Scap
- cholesterol homeostasis
- endoplasmic reticulum
- Experimental organism
- E. coli
- human
- mouse
-
Alejandro San Martín
Centro de Estudios Científicos, Chile
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Cell Biology
- Research focus
- imaging
- metabolism
- FRET
- single-fluorophore
- single-cell
- cell physiology
- optogenetics
-
Rajan Sankaranarayanan
CSIR – Centre for Cellular and Molecular Biology, India
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- crystal structure
- mechanism
- translation of genetic code
- proofreading
- editing
- tRNA synthetase
- Experimental organism
- E. coli
-
Shimon Schuldiner
The Hebrew University of Jerusalem, Israel
- Expertise
- Biochemistry and Chemical Biology
- Microbiology and Infectious Disease
- Research focus
- ion-coupled transporters
- neurotransporters
- multidrug transporters
- vesicular transporters
- antibiotic resistance
- bioenergetics
- microbial physiology
- membrane proteins
-
Marcus M Seldin
University of California, Irvine, United States
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Genetics and Genomics
- Research focus
- systems genetics
- endocrine physiology
- metabolism
- cell-cell communication
-
James R Sellers
National Heart, Lung and Blood Institute, National Institutes of Health, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Developmental Biology
- Research focus
- myosin
-
Akira Shinohara
Osaka University, Japan
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Cell Biology
- Research focus
- recombination
- DSB repair
- meiosis
- chromosome
- DNA damage response
- Experimental organism
- S. cerevisiae
- human
- mouse
-
Gustavo Monteiro Silva
Duke University, United States
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- ubiquitin
- oxidative stress
- translation
- proteomics
- Experimental organism
- human
- mouse
- S. cerevisiae
-
Jungsan Sohn
Johns Hopkins University School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Immunology and Inflammation
- Microbiology and Infectious Disease
- Research focus
- innate immunity
- inflammasomes
- X-ray crystallography
- cryo-EM
- biochemistry
- enzyme kinetics
-
Jonathan S Stamler
Case Western Reserve University, United States
- Expertise
- Medicine
- Biochemistry and Chemical Biology
- Research focus
- S-nitrosylation
- nitric oxide
- redox
- redox-signaling
- cysteine
- thiols
-
Randy B Stockbridge
University of Michigan, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- transporters
- microbial membrane proteins
- crystallography
- electrophysiology
- Experimental organism
- E. coli
-
N. Ravi Sundaresan
Indian Institute of Science, India
- Expertise
- Cell Biology
- Medicine
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Stem Cells and Regenerative Medicine
- Research focus
- reversable acetylation
- ADP-ribosylation
- cellular senescence and aging
- sirtuins
- cardiac and skeletal muscle diseases
- fibrosis
- Experimental organism
- human
- mouse
- rat
-
Thomas Surrey
The Francis Crick Institute, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- cytoskeleton
- spindle assembly
- cell division
- motor proteins
- microtubules
- self-organization
- active networks
- Experimental organism
- human
-
Alan Talevi
National University of La Plata, Argentina
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Research focus
- bioinformatics
- drug discovery
- cheminformatics
- pharmacy
-
Ivan Topisirovic
Jewish General Hospital, Canada
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Cell Biology
- Research focus
- mRNA translation
- signaling
- metabolic regulation
- protein quality control
- Experimental organism
- mouse
- human
-
Mohamed Trebak
University of Pittsburgh School of Medicine, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Cell Biology
- Biochemistry and Chemical Biology
- Research focus
- calcium channels
- receptor signalling
- ion channel regulation
- vascular remodeling
- smooth muscle
-
Julie P I Welburn
University of Edinburgh, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- mitosis
- cytoskeleton
- motors
- phosphorylation
- kinase
- microtubule
- cilia
- kinetochore
- Experimental organism
- human
- in vitro
-
R Luke Wiseman
Scripps Research, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- proteostasis
- stress-responsive signaling
- unfolded protein response
- protein secretion
- mitochondria regulation
- small molecule development
-
Jie Xiao
Johns Hopkins University, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Chromosomes and Gene Expression
- Microbiology and Infectious Disease
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- single molecule biophysics
- microbiology
- cell division
- cell wall
- gene expression
- Experimental organism
- E. coli
-
Keqiang Ye
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, China
- Expertise
- Medicine
- Cancer Biology
- Biochemistry and Chemical Biology
- Neuroscience
- Research focus
- neuroscience
- molecular cytobiology
- cancer biology
- neurodegenerative disease
- Experimental organism
- mouse
-
Qing Zhang
University of Texas Southwestern Medical Center, United States
- Expertise
- Cancer Biology
- Biochemistry and Chemical Biology
- Research focus
- CRISPR
- cancer metabolism
- hypoxia
- kidney cancer
- breast cancer
- epigenetics
- post-translational modifications
- synthetic lethality
