Editors for Biochemistry and Chemical Biology

We aim to review studies that provide new insights into the structure, function, and regulation of biological molecules including proteins, nucleic acids, lipids, carbohydrates, and natural products. In addition, we are interested in studies that illuminate complex biological processes using chemical tools and approaches. Read the latest research in this subject area.

Senior editors

  1. Anna Akhmanova

    Utrecht University, Netherlands

    Anna Akhmanova is a Professor of Cell Biology at the Department of Biology, Faculty of Science, Utrecht University, the Netherlands. She studied biochemistry and molecular biology at the Moscow State University and obtained her PhD at the University of Nijmegen, the Netherlands. Akhmanova studies cytoskeletal organization and trafficking processes, which contribute to cell polarization, differentiation, vertebrate development and human disease. The main focus of the work in her group is the microtubule cytoskeleton. Research in the group relies on combining high-resolution live cell imaging and quantitative analysis of cytoskeletal dynamics with in vitro reconstitution experiments. Her work has resulted in identification and characterization of a broad variety of factors which control microtubule organization and dynamics and motor attachment to membrane organelles. Anna Akhmanova is an elected member of the European Molecular Biology Organization and the Royal Netherlands Academy of Arts and Sciences.

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Research focus
    cytoskeleton
    cytoskeletal dynamics
    microtubules
    microtubule-binding proteins
    motor proteins
    membrane transport
    cell migration
    Experimental organism
    human cells
    mouse
    Competing interests statement
    Anna Akhmanova receives funding from the European Research Council, Human Frontier Science Program, and the Netherlands Organization for Scientific Research. She is a member of the Scientific Advisory Board of the Netherlands Institute for Neuroscience. She served on the editorial boards of BMC Cell Biology and Journal of Biological Chemistry. She is a currently on the editorial boards of PLOS Biology, Journal of Cell Science, Traffic, and BioArchitecture.
  2. Richard Aldrich

    Richard Aldrich

    The University of Texas at Austin, United States

    Rick Aldrich is the Karl Folkers Chair II in Interdisciplinary Biomedical Research and Professor of Neuroscience at The University of Texas at Austin. He joined the faculty in 2006 and served as chair until 2011. Previously he was on the faculty of Neurobiology (1985-1990) and of Molecular and Cellular Physiology (1990-2006) at Stanford University where he served as department chair from 2001–2004. He was an investigator with the Howard Hughes Medical Institute from 1990 to 2006. His work is on molecular mechanisms of ion channels and calcium signaling proteins, with an emphasis on understanding gated conformational changes and allosteric mechanisms. Work in the laboratory is multidisciplinary including electrophysiology, biochemistry, spectroscopy, informatics and computation. He is a member of the National Academy of Science and the American Academy of Arts and Sciences, and is a Fellow of the American Association for the Advancement of Science and of the Biophysical Society. He is past president of the Biophysical Society and the Society of General Physiologists, and has received the Kenneth Cole Award for Membrane Physiology from the Biophysical Society and Alden Spencer Award for Neuroscience Research from Columbia University.

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Biochemistry and Chemical Biology
    Research focus
    ion channels
    calcium binding proteins
    membrane transport
    allostery and cooperativity
    cellular neurophysiology
    biochemical neuroscience
    Competing interests statement
    Richard Aldrich is employed by The University of Texas at Austin. He receives research funding from the National Institutes of Health. He is a member of the National Academy of Science and the American Academy of Arts and Sciences, and is a Fellow of the American Association for the Advancement of Science and of the Biophysical Society. He serves actively on the editorial boards of Proceedings of the National Academy of Sciences and The Journal of General Physiology.
  3. Amy H Andreotti

    Iowa State University, United States

    Amy Andreotti is the Roy J Carver Chair in Biochemistry and a University Professor at Iowa State University. She joined the faculty of the Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology in 1997 after earning her PhD in Chemistry at Princeton University and completing a postdoctoral training period in the Chemistry Department at Harvard University where she was a Science Scholar at the Bunting Institute of Radcliffe College. Her work explores the mechanisms of kinase regulation during cell signaling with an emphasis on the immune specific TEC family of non-receptor tyrosine kinases. A particular focus of the lab is Bruton’s tyrosine kinase (BTK) and its interactions with small molecule therapeutics. Her lab uses a variety of biochemical, enzymatic and structural biology methods including solution NMR spectroscopy.

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    NMR spectroscopy
    kinase regulation
    cell signalling
    Tec family kinases
    Experimental organism
    human
    Competing interests statement
    Amy Andreotti's research is currently funded by the National Institutes of Health. She also serves on the National Advisory Committee for the Biomedical Scholars program of the Pew Charitable Trusts.
  4. Nancy Carrasco

    Vanderbilt University School of Medicine, United States

    Nancy Carrasco is the Joe C. Davis Professor and Chair of the Department of Molecular Physiology and Biophysics at the Vanderbilt University School of Medicine. She obtained her MD and Master’s in Biochemistry from the National Autonomous University of Mexico in her native Mexico City. Dr Carrasco did her postdoctoral work at the Roche Institute of Molecular Biology in New Jersey, for which she received a Fogarty International Fellowship. She then joined the Department of Molecular Pharmacology at the Albert Einstein College of Medicine, and later the Department of Cellular and Molecular Physiology at the Yale School of Medicine. Dr Carrasco has a longstanding interest in transport across biological membranes and in the role of membrane proteins in physiology and pathophysiology. Her cloning of the sodium/iodide symporter (NIS) has had numerous ramifications for many other fields, including structure/function of transport proteins, molecular endocrinology, gene transfer studies, cancer, and public health (she has served on the EPA’s Science Advisory Board). She has received numerous awards, including the Pew Award; the Arnold and Mabel Beckman Foundation Award; the Maria Sibylla Merian Award (Germany); the Merck Prize from the European Thyroid Association (Poland); the Rose Pitt-Rivers Lectureship at the British Endocrine Society Meeting (Scotland); the Noun Shavit Award (Israel); the Marshall S. Horwitz Faculty Prize for Research Excellence; and the Light of Life Award. She has served as president of the Society of Latin American Biophysicists. Dr Carrasco was elected to the National Academy of Sciences in 2015 and to the National Academy of Medicine in 2020.

    Expertise
    Medicine
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    molecular endocrinology
    biochemistry of membrane proteins
    biophysics of membrane proteins
    mechanistic information of NIS
    regulation of NIS
    sodium/iodide symporter
    cross-talk between hormones
    metabolism
    Experimental organism
    mouse
    human
    Competing interests statement
    Dr Carrasco’s research has been funded by NIH. She is on the NICHD Board of Scientific Counselors.
  5. Qiang Cui

    Boston University, United States

    Qiang Cui is a professor of Chemistry at Boston University and also affiliated with the Departments of Physics and Biomedical Engineering. He received a B.S. in Chemical Physics from the University of Science and Technology of China in 1993, and a Ph.D. in Theoretical Chemistry in 1997 from Emory University under the tutelage of Professor Keiji Morokuma. He conducted postodctoral research with Professor Martin Karplus at Harvard University and, in 2001, moved to the University of Wisconsin, Madison, as a faculty member in the Chemistry department. After spending almost 17 wonderful years in Madison, he moved back to Boston in 2018. His current research interests include quantum chemistry and statistical mechanics and their applications to various chemical, biological, and materials problems.

    Expertise: Computational biophysics, especially molecular dynamics, hybrid quantum mechanical/molecular mechanics simulations, free energy simulations applied to enzymes, biomolecular machines and lipid membranes.

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    molecular dynamics
    hybrid quantum
    classical simulations
    enzyme catalysis
    allostery
    protein dynamics
    membrane remodeling
    Competing interests statement
    Qiang Cui currently serves as an associate editor for the Journal of Chemical Theory and Computation (American Chemical Society).
  6. Volker Dötsch

    Goethe University, Germany

    Volker Dötsch is Professor of Biophysical Chemistry at Goethe University and a member of the Magnetic Resonance Center Frankfurt. He studied chemistry at the University of Göttingen and obtained a PhD from the ETH in Zürich. As a postdoctoral fellow he used NMR to determine the structure of protein-DNA complexes at the Harvard Medical School. In 1998 he moved as assistant professor to the University of California San Francisco (UCSF). In 2003 he was appointed professor at the Institute of Biophysical Chemistry of Goethe University in Frankfurt. His research interests focus on the structural and functional characterization of members of the p53 protein family, in particular p63 and its involvement in genetic quality control in germ cells. In addition, his laboratory uses a combination of NMR spectroscopy and cell-free protein expression to investigate the structure and function of membrane proteins and studies molecular interactions regulating autophagy. His lab uses a wide variety of biophysical methods including NMR spectroscopy and combines these studies with investigations in cell culture experiments and mouse models. Volker Dötsch is an elected EMBO member.

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    p53 protein family
    cell-free expression and membrane protein structure and function
    autophagy
    Competing interests statement
    Volker Dötsch has received funding from the Deutsche Forschungsgemeinschaft, the National Institutes of Health and the Deutsche Krebshilfe. He is on the Scientific Advisory Board of the Frankfurt Institute of Advanced Studies and a member of the editorial boards of Journal of Biological Chemistry and Cell Death & Disease.
  7. David James

    University of Sydney, Australia

    Professor James currently holds the Leonard P Ullmann Chair in Molecular Systems Biology and he is the Domain Leader for Biology at the Charles Perkins Centre, University of Sydney. Professor James has made major contributions to our understanding of insulin action. In the late 1980s he published a series of journal articles in Nature describing the identification and characterization of the insulin responsive glucose transporter GLUT4. Professor James then focused his efforts on unveiling the cellular and molecular control of insulin-stimulated glucose transport. He has also made contributions in the area of SNARE proteins, signal transduction and more recently in systems biology.

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    diabetes
    signal transduction
    systems biology
    Experimental organism
    mouse
    human
    rat
    Competing interests statement
    David James has been funded by bodies like National Health and Medical Research Council (NHMRC), Wellcome Trust, Australian Research Council (ARC), NIH, Pfizer, Eli Lilly and Novo, had continuous NHMRC research fellowships since 1998 and is now Senior Principal Research Fellow.

    James has served on editorial boards of journals such as The Journal of Biological Chemistry and The American Journal of Physiology for more than 10 years and is currently on five boards with major roles at Cell Metabolism (only Australian) and The Journal of Clinical Investigation. James reviews ~30 manuscripts per year for journals like Nature, Nature Cell Biology, Nature Medicine, Science, PNAS, The Journal Clinical Invest, Molecular Endocrinology, Endocrinology, Molecular Biology of the Cell, Journal of Cell Biology, Traffic, FASEB J, Genes & Development and grants for Diabetes Australia, National Heart, Wellcome Trust, ARC, NHMRC and International Foundations.
  8. Benoît Kornmann

    University of Oxford, United Kingdom

    Benoit Kornmann is Associate Professor at the Department of Biochemistry, University of Oxford, and fellow of St Hugh’s College. Benoit Kornmann studies membrane contact sites, how intracellular organization impinges on organelle function and how lipid molecules are distributed among the many membranes of a eukaryotic cell. Benoit Kornmann is an expert in yeast genetics, membrane biology, organelle dynamics and signalling. He holds a PhD of the University of Geneva, and previously held the positions of Assistant Professor at the ETH Zurich, Professor of the Swiss National Science Foundation, and fellow of the Swiss National Science Foundation.

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Genetics and Genomics
    Research focus
    membrane contact sites
    mitochondria
    membrane dynamics
    membrane trafficking
    phospholipids
    Experimental organism
    S. cerevisiae
    Competing interests statement
    Benoit Kornmann is funded by the Wellcome trust and Syngenta Crop Protection. He is a board member of Review Commons and Contact, a faculty member of Faculty Opinions, and an advisory board member of F1000 Research.
  9. Merritt Maduke

    Stanford University School of Medicine, United States

    Merritt Maduke is an Associate Professor of Molecular & Cellular Physiology and co-director of the Neurosciences Interdisciplinary Graduate Program at Stanford University School of Medicine. She received her PhD in Chemistry from the University of California, San Diego and did postdoctoral training at Brandeis University with Professor Chris Miller. Her research at Stanford is centered on the biophysics of ion channels and transporters, with the overarching goal of understanding molecular mechanisms within the context of physiological functions. She also applies her mechanistic approach in the field of ultrasound neuromodulation. She was awarded the Society of General Physiologist’s Cranefield Award for her research on ion channels (2008) and served as the Society’s President from 2018-2019.

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Biochemistry and Chemical Biology
    Research focus
    ion channel and transporter molecular mechanisms
    ion channel and transporter physiology
    ion channel and transporter pharmacology
    ultrasound neuromodulation
    Experimental organism
    E. coli
    mouse
    rat
    Competing interests statement
    Merritt Maduke is employed by Stanford University and receives research funding from the National Institutes of Health and Stanford Innovative Medicine Accelerator. She has served on the BPNS and BBM study sections at the NIH and as ad hoc member of additional panels. She serves on the editorial boards of the Biophysical Journal and The Journal of General Physiology and is a founding curator for Biophysics Colab.
  10. Vivek Malhotra

    The Barcelona Institute of Science and Technology, Spain

    Vivek Malhotra was a professor in the biology division at UC San Diego from 2007 and is now the ICREA Professor and Chair of the Cell and Developmental Biology at Center for Genomic Regulation (CRG) in Barcelona. His research focuses on a central station of the secretory pathway, the Golgi complex. Specifically, his work has resulted in the identification of the machinery required for the sorting and packaging of secretory cargoes. His recent work has uncovered a novel secretory routing that bypasses the conventional pathway of protein secretion. He has identified new genes required for the export of bulky collagens and the regulated secretion of mucins. He received his BSc from Stirling University and was a Pirie–Reid scholar at Oxford, a Damon Runyon Walter Winchell and an American Cancer Society postdoctoral fellow at Stanford, and Basil O’Conner scholar, established Investigator of the American Heart Association, and Senior Investigator of Sandler’s Foundation for Asthma at UC San Diego. He received the MERCK award from the American Society of Biochemistry and Molecular Biology, is a fellow of the American association of the arts and science, and is an elected EMBO member.

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    Golgi membranes
    protein secretion
    collagen
    mucins
    unconventional protein secretion
    Competing interests statement
    Vivek Malhotra receives funding from ERC/European Research Council, Ministerio de Economía y Competitividad, AGAUR and the Plan Nacional (Spain) He is a Scientific Advisory Board member of TIGEM (Naples, Italy), CNR (Naples, Italy), CBMSO (Madrid, Spain) and Department of Biotechnology (India). He has served on the editorial board of Cell and was an associate editor of Molecular Biology of the Cell. He is currently on the editorial boards of Journal of Cell Biology and Current Opinion in Cell Biology.
  11. Suzanne R Pfeffer

    Stanford University School of Medicine, United States

    Suzanne Pfeffer is the Emma Pfeiffer Merner Professor of Medical Sciences and Professor of Biochemistry at Stanford University School of Medicine. She is an expert in the field of membrane trafficking in the secretory and endocytic pathways, and her research currently focuses on the molecular basis of LRRK2-mediated, familial Parkinson's Disease and Niemann Pick Type C disease, with emphasis on Rab GTPase regulation and cholesterol export from lysosomes. She is a past President of the American Society for Cell Biology and the American Society of Biochemistry and Molecular Biology and a Fellow of the American Society for Cell Biology, the American Association for the Advancement of Science and the American Academy of Arts and Sciences.

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Neuroscience
    Research focus
    membrane trafficking
    endosomes
    lysosomes
    Golgi complex
    neurodegeneration
    Parkinson's disease
    endocytosis
    secretory pathway
    Rab GTPase
    primary cilia
    Experimental organism
    human
    mouse
    Competing interests statement
    Suzanne Pfeffer's research is currently funded by the National Institutes of Health, the Michael J. Fox Foundation and the Ara Parseghian Medical Research Foundation. She serves on the Scientific Advisory Board of the Ara Parseghian Medical Research Foundation, the Swiss National Science Foundation funded NCCR program in Chemical Biology at the EPFL and University of Geneva, and she is a chartered member of the NIH NCSD review panel. Suzanne Pfeffer also serves as Co-Section Head for Membranes and Sorting, Faculty of 1000.
  12. David Ron

    Cambridge University, United Kingdom

    David Ron is a Professor at Cambridge University. He directs a lab at the Cambridge Institute for Medical Research (CIMR) studying protein-folding homeostasis in the endoplasmic reticulum (ER). The lab uses biochemical, biophysical and cell-based tools to research both the molecular mechanisms that recognize the burden of unfolded proteins and thus initiate signalling in the ER unfolded protein response (UPR) and the downstream effector pathways by which cells adapt to unfolded protein stress in their ER. These effector mechanisms engage post-translational regulation of ER chaperone function, regulated translation of mRNA and transcriptional control of gene expression and thus interface with other cellular stress pathways.

    To eLife, David Ron brings scientific expertise in the study of the unfolded protein response, chaperone function and stress-induced regulation of mRNA translation and editorial experience from having served as an eLife Reviewing Editor since 2012.

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    chaperones
    unfolded protein response
    oxidative protein folding
    protein synthesis
    Experimental organism
    C. elegans
    E. coli
    human
    mouse
    S. cerevisiae
    Competing interests statement
    David Ron holds a Wellcome Trust Principal Research Fellowship and is on the editorial advisory boards of J. Cell Science, PLOS Biology and EMBO J.
  13. Dominique Soldati-Favre

    University of Geneva, Switzerland

    Dr Dominique Soldati-Favre studied biochemistry and earned her PhD degree in molecular biology from the University of Zürich (Switzerland). She is full Professor at the department of Microbiology and Molecular Medicine at the Faculty of Medicine of the University of Geneva. Her laboratory is studying obligate intracellular parasitism using Toxoplasma gondii. The main line of research focuses on the cell biology underlying parasite active invasion into mammalian cells. Her group is also aiming at defining the metabolic needs and capabilities of the parasites as well as how they subvert host cellular functions notably to access nutrients.

    Expertise
    Microbiology and Infectious Disease
    Biochemistry and Chemical Biology
    Cell Biology
    Genetics and Genomics
    Research focus
    parasitology
    organelle biogenesis
    protein trafficking
    metabolism
    host pathogen interaction
    signalling
    Experimental organism
    T. gondii
    apicomplexans
    kinetoplastids
    Competing interests statement
    Dominique Soldati-Favre’s research is currently funded by the Swiss National Science Foundation. She serves as Section Editor at PLOS Pathogens, and Editor at mBio.
  14. Kenton J Swartz

    National Institute of Neurological Disorders and Stroke, NIH, United States

    Kenton Swartz has been a Senior Investigator in the National Institute of Neurological Disorders and Stroke within the National Institutes of Health in Bethesda, Maryland since 2003. He obtained a BS in Chemistry and Biology from Eastern Mennonite College in 1986 and a PhD in Neurobiology from Harvard Medical School in 1993, where he worked with Bruce Bean studying the regulation of voltage-gated calcium channels by G-proteins and protein kinases. He obtained postdoctoral training with Roderick MacKinnon at Harvard Medical School, where he began isolating and studying toxins that interact with voltage-activated potassium channels. His laboratory uses biochemical, molecular biological, biophysical and structural techniques to understand how ion channel proteins sense critical biological stimuli, including membrane voltage, temperature, and both chemical and mechanical signals. He received an NIH Directors Award for Scientific Achievement in 2008, an NIH Office of the Director Honor Award on behalf of the Diversity Task Force in 2011 and the Kenneth S. Cole Award from the Biophysical Society in 2017. He has also served as the president of the Society of General Physiologists.

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Biochemistry and Chemical Biology
    Research focus
    ion channel structure
    ion channel mechanisms
    ion channel physiology
    ion channel pharmacology
    Experimental organism
    mouse
    Competing interests statement
    Kenton Swartz is employed by the Intramural Research Program of the National Institute of Neurological Disorders and Stroke, National Institutes of Health. In addition to serving as a Senior Editor at eLife, he has served as a Reviewing Editor for eLife and as an Associate Editor at the Journal of General Physiology. He also teaches yoga at LifeTime Athletic.

Reviewing editors

  1. Fernán Agüero

    Universidad Nacional de San Martín, Argentina

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Computational and Systems Biology
    Evolutionary Biology
    Genetics and Genomics
    Immunology and Inflammation
    Microbiology and Infectious Disease
    Research focus
    genomics
    drug discovery
    diagnostics
    infectious diseases
    microbial eukaryotes
    bioinformatics
  2. Caetano Antunes

    University of Kansas, United States

    Expertise
    Biochemistry and Chemical Biology
    Genetics and Genomics
    Microbiology and Infectious Disease
    Research focus
    microbiome
    host-microbe interactions
    metabolomics
    gene regulation
    microbial signaling
  3. Demet Araç

    University of Chicago, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    G protein-coupled receptors (GPCR)
    synapse formation
    cell adhesion
  4. Hossein Ardehali

    Northwestern University, United States

    Expertise
    Medicine
    Biochemistry and Chemical Biology
    Research focus
    mitochondria
    iron
    glucose metabolism
    mRNA-binding proteins
    hexokinases
    metabolism
    cardiac biology
  5. Muthuswamy Balasubramanyam

    ICMR Emeritus Scientist, Madras Diabetes Research Foundation, India

    Expertise
    Medicine
    Biochemistry and Chemical Biology
    Cancer Biology
    Cell Biology
    Developmental Biology
    Epidemiology and Global Health
    Genetics and Genomics
    Immunology and Inflammation
    Neuroscience
    Stem Cells and Regenerative Medicine
    Research focus
    disease biology
    diabetes
    aging
    omnics
    calcium signaling
    endocrine disruptors
    probiotics
    molecular medicine
  6. Anton M Bennett

    Yale University, United States

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Cancer Biology
    Research focus
    cell signalling
    metabolism
    protein tyrosine phosphorylation
    protein tyrosine kinases
    protein tyrosine phosphatases
  7. Douglas L Black

    University of California, Los Angeles, United States

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Research focus
    RNA splicing
    alternative splicing
    RNA binding proteins
    post-transcriptional gene regulation
    neuronal gene expression
    neuronal development
    polypyrimidine tract binding proteins
    Rbfox proteins
    Experimental organism
    mammalian cells
    mouse
    ES cell models
  8. Amie K Boal

    Pennsylvania State University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    bioinorganic chemistry
    enzymes
    microbial chemistry
    x-ray crystallography
  9. Michael R Botchan

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Research focus
    DNA replication
    DNA repair
    Experimental organism
    D. melanogaster
  10. Paula Casati

    Center of Photosynthetic And Biochemical Studies (CEFOBI), Argentina

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Plant Biology
    Research focus
    genome stability
    abiotic stress in plants
    chromatin remodelling
    cell cycle regulation
    flavonoid metabolism
  11. Agnieszka Chacinska

    University of Warsaw, Poland

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    biogenesis
    organelles
    mitochondria
    protein transport
    proteasome
    protein degradation
    protein synthesis
    Experimental organism
    S. cerevisiae
    mammalian cells
    nematode
  12. Pimchai Chaiyen

    Vidyasirimedhi Institute of Science and Technology (VISTEC), Thailand

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    Enzyme
    flavin
    mechanism
    biocatalysis
    metabolic engineering
    bioluminescence
    Experimental organism
    E. coli
    Pseudomonas
  13. Lydia Contreras

    The University of Texas at Austin, United States

    Expertise
    Biochemistry and Chemical Biology
    Microbiology and Infectious Disease
    Research focus
    bacteria
    regulatory RNAs
    sRNAs
    bacterial regulation
    epitranscriptomics
    RNA modifications
  14. Laura Dassama

    Stanford University, United States

    Expertise
    Biochemistry and Chemical Biology
    Microbiology and Infectious Disease
    Research focus
    bacterial multidrug resistance
    chemoenzymatic syntheses
    beta-hemoglobinopathies
  15. Irwin Davidson

    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Chromosomes and Gene Expression
    Research focus
    transcription
    chromatin
    genomics
    cancer
    Experimental organism
    human
    mouse
  16. Roger J Davis

    University of Massachusetts Medical School, United States

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Cell Biology
    Research focus
    diabetes
    NAFLD
    NASH
    metabolism
    insulin resistance
    cancer
    signal transduction
    Experimental organism
    mouse
    human
  17. Gina M DeNicola

    Moffitt Cancer Center, United States

    Expertise
    Cancer Biology
    Biochemistry and Chemical Biology
    Research focus
    tumor metabolism
    redox biology
    ROS
    sulfur metabolism
    NRF2/KEAP1
    mouse models of cancer
  18. Martin S Denzel

    Altos Labs, Cambridge Institute of Science, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Genetics and Genomics
    Research focus
    aging
    metabolism
    protein homeostasis
    cell culture
    Experimental organism
    C. elegans
    mouse
  19. Ivan Dikic

    Goethe University Frankfurt, Germany

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Cancer Biology
    Microbiology and Infectious Disease
    Research focus
    ubiquitination
    autophagy
    ER remodelling
    infection
    virus
    bacteria
    cancer
    Experimental organism
    mouse
    C. elegans
    S. cerevisiae
  20. David Drew

    University of Stockholm, Sweden

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    membrane transporters
    x-ray crystallography
    cryo-EM
    membrane protein biotechnology
    bioenergetics
    solute carrier (SLC) transport
  21. Stephen C Ekker

    Mayo Clinic, United States

    Expertise
    Developmental Biology
    Biochemistry and Chemical Biology
    Research focus
    gene editing
    morpholinos
    transposons
    mitochondria
    health engineering
    Experimental organism
    zebrafish
  22. Aaron Frank

    University of Michigan, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    molecular modeling
    biophysics
    structural biology
    computation
    RNA biochemistry
    RNA structural biology
  23. Adam Frost

    University of California, San Francisco, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    cryo-EM
    electron cryo-microscopy
    membranes
    membrane remodeling
    proteostasis
    stress responses
    translation
    mitochondria
    nuclear envelope
    intracellular trafficking
  24. Karine A Gibbs

    Harvard University, United States

    Expertise
    Microbiology and Infectious Disease
    Biochemistry and Chemical Biology
    Research focus
    Proteus mirabilis
    sociomicrobiology
    bacterial genetics
    kin discrimination
    self/non-self recognition
  25. Gustavo H Goldman

    Universidade de Sao Paulo, Brazil

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Microbiology and Infectious Disease
    Research focus
    filamentous fungi
    Aspergillus
    secondary metabolites
    gene expression
    molecular biology
    infectious diseases
    drug tolerance
  26. Ruben Gonzalez

    Columbia University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    translation
    translational control
    ribosomes
    RNA
    tRNA
    single-molecule biophysics
    single-molecule fluorescence resonance energy transfer
    cryo-EM
    biochemistry
    live cell imaging
    Experimental organism
    B. subtilis
    E. coli
    human
    S. cerevisiae
  27. Martin Graña

    Institut Pasteur de Montevideo, Uruguay

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Evolutionary Biology
    Physics of Living Systems
    Structural Biology and Molecular Biophysics
    Research focus
    protein 3D structure
    structural bioinformatics
    structure/function relationships
    evolution
  28. Rebekah L. Gundry

    University of Nebraska Medical Center, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Stem Cells and Regenerative Medicine
    Research focus
    mass spectrometry
    cell surface glycoproteins
    proteomics
    glycomics
    heart failure
    stem cell derived cardiomyocytes
    biomarkers
  29. Iqbal Hamza

    University of Maryland, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Genetics and Genomics
    Research focus
    metals
    anemia
    iron
    heme
    Experimental organism
    mouse
    C. elegans
    parasites
  30. Franz-Ulrich Hartl

    Max Planck Institute of Biochemistry, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    protein folding
    molecular chaperones
    neurodegenerative disorders
  31. Heedeok Hong

    Michigan State University, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    membrane proteins
    membrane protein folding
    membrane protein stability
    rhomboid proteases
    ATP-dependent proteolysis
    AAA+
    GlpG
    FtsH
  32. Pankaj Kapahi

    Buck Institute for Research on Aging, United States

    Expertise
    Biochemistry and Chemical Biology
    Developmental Biology
    Research focus
    aging
    age-related diseases
    nutrient signaling
    metabolism
    inflammation
    Experimental organism
    C. elegans
    D. melanogaster
    E. coli
    mouse
  33. Mary B Kennedy

    California Institute of Technology, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Neuroscience
    Research focus
    synaptic plasticity
    synaptic regulation
    biochemical signal transduction networks
    systems biology
    Experimental organism
    mouse
    rat
  34. Daniel J Kliebenstein

    University of California, Davis, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Ecology
    Genetics and Genomics
    Plant Biology
    Research focus
    genetics
    genomics
    transcriptomics
    metabolomics
    pathogen
    plant metabolism
    fitness
    Experimental organism
    A. thaliana
    B. cinerea
    eudicots
  35. David M Kramer

    Michigan State University, United States

    Expertise
    Biochemistry and Chemical Biology
    Plant Biology
    Physics of Living Systems
    Computational and Systems Biology
    Research focus
    photosynthesis
    bioenergetics
    electron and proton transfer
    computation
    phenotyping
    phenomics
  36. Yamuna Krishnan

    University of Chicago, United States

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    nucleic acid-based molecular devices
    DNA machines
    chemical biology
    synthetic biology
    bioengineering
    Experimental organism
    C. elegans
  37. Karsten Kruse

    University of Geneva, Switzerland

    Expertise
    Biochemistry and Chemical Biology
    Physics of Living Systems
    Research focus
    cell migration
    cell signalling
    theoretical biology
    molecular evolution
  38. Tatiana G Kutateladze

    University of Colorado School of Medicine, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    epigenetics
    chromatin
    protein structure
    NMR spectroscopy
    molecular mechanisms
    Experimental organism
    human
  39. Ashish Lal

    National Institutes of Health, United States

    Expertise
    Cancer Biology
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    RNA biology
    lncRNAs
    microRNAs
    gene regulation
    cancer biology
    p53
    Experimental organism
    human
  40. Joanne Lemieux

    University of Alberta, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    protease
    intramembrane protease
    crystallography
    membrane proteins
    structural biology
  41. Hongliang Li

    Wuhan University School of Medicine, China

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Epidemiology and Global Health
    Immunology and Inflammation
    Medicine
    Research focus
    cardiometabolic disease
    metabolic disease
    vascular injury
    animal models
    liver
    innate immunity
  42. Sebastian Lourido

    Whitehead Institute for Biomedical Research, United States

    Expertise
    Microbiology and Infectious Disease
    Cell Biology
    Genetics and Genomics
    Biochemistry and Chemical Biology
    Research focus
    calcium signaling
    host-pathogen interactions
    genetic screening
    protein kinases
    genomics
    quantitative proteomics
    Apicomplexan parasites
    Experimental organism
    T. gondii
    P. falciparum
  43. Kristen W Lynch

    University of Pennsylvania, United States

    Expertise
    Chromosomes and Gene Expression
    Biochemistry and Chemical Biology
    Genetics and Genomics
    Research focus
    RNA
    post-transcriptional gene regulation
    RNA silencing
    RNA binding proteins
  44. Koyeli Mapa

    Shiv Nadar University, India

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    proteostasis
    chaperones
    stress response
    unfolded protein response
    heat shock proteins
    mitochondria
    protein folding
    Experimental organism
    yeast
    human cells
    E. coli
  45. Andreas Martin

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    AAA+ ATPases
    protein degradation
    proteostasis
    ATPase mechanism
    protein folding
  46. Malcolm J McConville

    University of Melbourne, Australia

    Expertise
    Microbiology and Infectious Disease
    Biochemistry and Chemical Biology
    Research focus
    protozoan parasites
    metabolomics
    metabolism
    Leishmaniasis
    trypanosomatids
    glycobiology
    Experimental organism
    T. gondii
  47. Marcelo A Mori

    State University of Campinas, Brazil

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Immunology and Inflammation
    Research focus
    aging
    metabolism
    obesity
    adipose tissue
    microRNAs
    endocrinology
    integrative physiology
  48. Hitoshi Nakatogawa

    Tokyo Institute of Technology, Japan

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Research focus
    molecular mechanisms of autophagy
    protein/organelle degradation
    membrane dynamics
    Experimental organism
    S. cerevisiae
  49. Geeta Narlikar

    University of California, San Francisco, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    chromatin
    heterochromatin spread
    chromatin remodeling machines
    phase-separation
  50. Hannes Neuweiler

    University of Würzburg, Germany

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    protein folding
    protein dynamics
    protein engineering
    fluorescence spectroscopy
    fluorescence probes
    kinetics
    single-molecule fluorescence spectroscopy
  51. Timothy Nilsen

    Case Western Reserve University, United States

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Research focus
    mRNA processing
    mechanism of miRNA function
    RNA protein interactions
    mRNP composition and function
    RNA biology
    Experimental organism
    D. melanogaster
  52. Kassandra Ori-McKenney

    University of California , United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Neuroscience
    Research focus
    microtubules
    microtubule-associated proteins
    microtubule motors
    tau neurofibrillary tangles
    neurodegeneration
    Experimental organism
    D. melanogaster
    mammalian cell culture
  53. Akhilesh Pandey

    Mayo Clinic, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Research focus
    proteomics
    quantitative proteomics
  54. Rohit V Pappu

    Washington University in St Louis, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Physics of Living Systems
    Research focus
    biophysics
    intrinsically disordered proteins
    intracellular phase transition phenomena
    organization of proteins and nucleic acids
  55. Jon Pines

    Institute of Cancer Research, University College London, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    cyclins and anaphase promoting complex/cycosome (APC/C)
    cell cycle
    mitosis
    spindle assembly checkpoint
    Experimental organism
    human
  56. Stephan Pless

    University of Copenhagen, Denmark

    Expertise
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    ion channels
    pharmacology
    electrophysiology
    biophysics
    chemical biology
    non-canonical amino acids
    protein engineering
    neurobiology
  57. Owen Pornillos

    University of Virginia, United States

    Expertise
    Microbiology and Infectious Disease
    Structural Biology and Molecular Biophysics
    Biochemistry and Chemical Biology
    Research focus
    higher-order assembly
    cell-free reconstitution
    retrovirus structure
    tripartite motif proteins
  58. Arun Radhakrishnan

    University of Texas Southwestern Medical Center, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    lipid sensors
    cholesterol
    sphingomyelin
    cholesterol transport
    SREBP
    Scap
    cholesterol homeostasis
    endoplasmic reticulum
    Experimental organism
    E. coli
    human
    mouse
  59. Marina V Rodnina

    Max Planck Institute for Biophysical Chemistry, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    translation
    ribosomes
    tRNA
    translation fidelity
    cotranslational protein folding
    recoding
    translation factors
    translation regulation
  60. Alejandro San Martín

    Centro de Estudios Científicos, Chile

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Cell Biology
    Research focus
    imaging
    metabolism
    FRET
    single-fluorophore
    single-cell
    cell physiology
    optogenetics
  61. Rajan Sankaranarayanan

    CSIR – Centre for Cellular and Molecular Biology, India

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    crystal structure
    mechanism
    translation of genetic code
    proofreading
    editing
    tRNA synthetase
    Experimental organism
    E. coli
  62. Shimon Schuldiner

    The Hebrew University of Jerusalem, Israel

    Expertise
    Biochemistry and Chemical Biology
    Microbiology and Infectious Disease
    Research focus
    ion-coupled transporters
    neurotransporters
    multidrug transporters
    vesicular transporters
    antibiotic resistance
    bioenergetics
    microbial physiology
    membrane proteins
  63. James R Sellers

    National Heart, Lung and Blood Institute, National Institutes of Health, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Developmental Biology
    Research focus
    myosin
  64. Nima Sharifi

    Cleveland Clinic, United States

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Medicine
    Research focus
    steroid biochemistry
    steroid metabolism
    prostate cancer
    nuclear receptors
    hormone therapy resistance
    androgens
    oncology
    Experimental organism
    mouse
  65. Akira Shinohara

    Osaka University, Japan

    Expertise
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Cell Biology
    Research focus
    recombination
    DSB repair
    meiosis
    chromosome
    DNA damage response
    Experimental organism
    S. cerevisiae
    human
    mouse
  66. Gustavo Monteiro Silva

    Duke University, United States

    Expertise
    Biochemistry and Chemical Biology
    Research focus
    ubiquitin
    oxidative stress
    translation
    proteomics
    Experimental organism
    human
    mouse
    S. cerevisiae
  67. Jungsan Sohn

    Johns Hopkins University School of Medicine, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Immunology and Inflammation
    Microbiology and Infectious Disease
    Research focus
    innate immunity
    inflammasomes
    X-ray crystallography
    cryo-EM
    biochemistry
    enzyme kinetics
  68. Jonathan S Stamler

    Case Western Reserve University, United States

    Expertise
    Medicine
    Biochemistry and Chemical Biology
    Research focus
    S-nitrosylation
    nitric oxide
    redox
    redox-signaling
    cysteine
    thiols
  69. Randy B Stockbridge

    University of Michigan, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    ion channels
    transporters
    microbial membrane proteins
    crystallography
    electrophysiology
    Experimental organism
    E. coli
  70. Thomas Surrey

    The Francis Crick Institute, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    cytoskeleton
    spindle assembly
    cell division
    motor proteins
    microtubules
    self-organization
    active networks
    Experimental organism
    human
  71. Alan Talevi

    National University of La Plata, Argentina

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Microbiology and Infectious Disease
    Structural Biology and Molecular Biophysics
    Research focus
    bioinformatics
    drug discovery
    cheminformatics
    pharmacy
  72. Ivan Topisirovic

    Jewish General Hospital, Canada

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Cell Biology
    Research focus
    mRNA translation
    signaling
    metabolic regulation
    protein quality control
    Experimental organism
    mouse
    human
  73. Mohamed Trebak

    University of Pittsburgh School of Medicine, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Cell Biology
    Biochemistry and Chemical Biology
    Research focus
    calcium channels
    receptor signalling
    ion channel regulation
    vascular remodeling
    smooth muscle
  74. Eric J Wagner

    University of Texas Medical Branch at Galveston, United States

    Expertise
    Chromosomes and Gene Expression
    Biochemistry and Chemical Biology
    Cancer Biology
    Genetics and Genomics
    Research focus
    RNA biology
    transcription
    RNA processing
    gene expression
  75. Julie P I Welburn

    University of Edinburgh, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    mitosis
    cytoskeleton
    motors
    phosphorylation
    kinase
    microtubule
    cilia
    kinetochore
    Experimental organism
    human
    in vitro
  76. Raymund Wellinger

    Université de Sherbrooke, Canada

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    chromosome biology
    DNA replication
    telomeres
    telomerase
    yeast cell biology
    Experimental organism
    yeast
    mouse
  77. R Luke Wiseman

    Scripps Research, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Research focus
    proteostasis
    stress-responsive signaling
    unfolded protein response
    protein secretion
    mitochondria regulation
    small molecule development
  78. Jie Xiao

    Johns Hopkins University, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Chromosomes and Gene Expression
    Microbiology and Infectious Disease
    Physics of Living Systems
    Structural Biology and Molecular Biophysics
    Research focus
    single molecule biophysics
    microbiology
    cell division
    cell wall
    gene expression
    Experimental organism
    E. coli
  79. Keqiang Ye

    Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, China

    Expertise
    Medicine
    Cancer Biology
    Biochemistry and Chemical Biology
    Neuroscience
    Research focus
    neuroscience
    molecular cytobiology
    cancer biology
    neurodegenerative disease
    Experimental organism
    mouse
  80. Ahmet Yildiz

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Physics of Living Systems
    Research focus
    dynein
    kinesin
    myosin
    intraflagellar transport
    Experimental organism
    human
    yeast
    Chlamydomonas
  81. Giulia Zanetti

    Birkbeck, University of London, United Kingdom

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    membrane trafficking
    coat proteins
    COPII
    membrane remodeling
    structural biology
    cryo-EM
    cryo-ET
    subtomogram averaging
    Experimental organism
    S. cerevisiae
  82. Qing Zhang

    University of Texas Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Biochemistry and Chemical Biology
    Research focus
    CRISPR
    cancer metabolism
    hypoxia
    kidney cancer
    breast cancer
    epigenetics
    post-translational modifications
    synthetic lethality