Biochemistry and Chemical Biology

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Genetically engineered mesenchymal stem cells as a nitric oxide reservoir for acute kidney injury therapy

   Haoyan Huang, Meng Qian ... Zongjin Li

   Engineered mesenchymal stem cells (MSCs) could produce mutant β-galactosidase and trigger nitric oxide (NO) release when the NO prodrug is systemically administered, which can achieve NO release in a precise spatiotemporal manner and augment the therapeutic efficiency of MSCs.
2. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP

   Maria Körner, Susanne R Meyer ... Alexander Buchberger

   The previously uncharacterized, evolutionarily conserved FAM104 proteins VCF1/2 stimulate the nuclear import of p97/VCP, with their absence causing reduced nuclear p97/VCP levels, slow growth, and hypersensitivity to pharmacological inhibition of p97/VCP.
3. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   A lipid transfer protein knockout library reveals ORP9-ORP11 dimer mediating PS/PI(4)P exchange at the ER-trans Golgi contact site to promote sphingomyelin synthesis

   Birol Cabukusta, Shalom Borst Pauwels ... Jacques Neefjes
4. 1. Biochemistry and Chemical Biology

   Conformation Selection by ATP-competitive Inhibitors and Allosteric Communication in ERK2

   Jake W. Anderson, David Vaisar ... Natalie G. Ahn
5. 1. Biochemistry and Chemical Biology
   2. Epidemiology and Global Health

   Status and physiological significance of circulating adiponectin in the very old and centenarians: an observational study

   Takashi Sasaki, Yoshinori Nishimoto ... Yasumichi Arai
6. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Vibrio cholerae's ToxRS bile sensing system

   Nina Gubensäk, Theo Sagmeister ... Tea Pavkov-Keller
7. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions

   Jixing Lyu, Tianqi Zhang ... Arthur Laganowsky
8. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Pushed to the edge: hundreds of Myosin 10s pack into filopodia and could cause traffic jams on actin

   Julia Shangguan, Ronald S. Rock
9. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growth

   Francesca G Tomasi, Satoshi Kimura ... Matthew K Waldor

   Surveying Mycobacterium tuberculosis tRNA modification leads to identification of a modification promoting Mtb pathogenesis.
10. 1. Biochemistry and Chemical Biology

    Structural rather than catalytic role for mitochondrial respiratory chain supercomplexes

    Michele Brischigliaro, Alfredo Cabrera-Orefice ... Erika Fernández-Vizarra