Biochemistry and Chemical Biology

Latest articles

1. 1. Biochemistry and Chemical Biology

   Structural rather than catalytic role for mitochondrial respiratory chain supercomplexes

   Michele Brischigliaro, Alfredo Cabrera-Orefice ... Erika Fernández-Vizarra
2. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Autophagosome membrane expansion is mediated by the N-terminus and cis-membrane association of human ATG8s

   Wenxin Zhang, Taki Nishimura ... Sharon A Tooze
3. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   The structural basis of the multi-step allosteric activation of Aurora B kinase

   Dario Segura-Peña, Oda Hovet ... Nikolina Sekulic

   An entropy switch controls the Aurora B autoactivation process through two distinct kinetic steps of phosphorylation.
4. 1. Biochemistry and Chemical Biology

   High-throughput Automated Muropeptide Analysis (HAMA) Reveals Peptidoglycan Composition of Gut Microbial Cell Walls

   Ya-Chen Hsu, Pin-Rui Su ... Cheng-Chih Hsu
5. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Calcium and bicarbonate signaling pathways have pivotal, resonating roles in matching ATP production to demand

   Maura Greiser, Mariusz Karbowski ... Liron Boyman
6. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Drug Discovery: Decoding the mechanisms of allostery

   Saif Khan, Cornelius Gati

   A complex interplay between structure, conformational dynamics and pharmacology defines distant regulation of G protein-coupled receptors.
7. 1. Biochemistry and Chemical Biology

   Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution

   Loïc Duffet, Elyse T Williams ... Tommaso Patriarchi

   A genetically encoded sensor and a photocaged peptide together enable precise investigation of human glucagon-like peptide-1 receptor activation with high spatiotemporal resolution.
8. 1. Biochemistry and Chemical Biology
   2. Immunology and Inflammation

   The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

   Minato Hirano, Gaddiel Galarza-Muñoz ... Mariano A Garcia-Blanco

   RNA processing regulates gene expression of the key transcription factor FOXP3 in T regulatory cells impacting immune tolerance and susceptibility to autoimmune disease.
9. 1. Biochemistry and Chemical Biology

   Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2

   Kehan Chen, Lie Wang ... Gang Wu
10. 1. Biochemistry and Chemical Biology

    Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

    F Lolicato, JP Steringer ... W Nickel