Biochemistry and Chemical Biology

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds

   Cristina Manatschal et al.
2. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling

   Pim J Huis in 't Veld et al.
3. 1. Biochemistry and Chemical Biology
   2. Genetics and Genomics

   Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy

   Camilla Nehammer et al.
4. 1. Biochemistry and Chemical Biology

   Exchange of water for sterol underlies sterol egress from a StARkin domain

   George Khelashvili et al.
5. 1. Biochemistry and Chemical Biology
   2. Neuroscience

   Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock

   Andrea Brenna et al.

   Cyclin-dependent kinase 5 regulates the circadian clock involving phosphorylation of the PER2 protein.
6. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA

   James Lee et al.

   Outer membrane β-barrel proteins in Gram-negative bacteria are assembled within the lumen of the BamA β-barrel.
7. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Modulating FOXO3 transcriptional activity by small, DBD-binding molecules

   Judith Hagenbuchner et al.
8. 1. Biochemistry and Chemical Biology

   Specific lid-base contacts in the 26S proteasome control the conformational switching required for substrate degradation

   Eric R Greene et al.
9. 1. Biochemistry and Chemical Biology

   Deamidation disrupts native and transient contacts to weaken the interaction between UBC13 and RING-finger E3 ligases

   Priyesh Mohanty et al.

   Post-translational modifications regulate transient protein-protein interactions to disrupt Ubiquitin enzyme/ligase complexes, a strategy used by Shigella to inactivate the host immune response.
10. 1. Biochemistry and Chemical Biology

    Non-enzymatic primer extension with strand displacement

    Lijun Zhou et al.

    Relying on RNA fragments derived from degradation or partial template copying, non-enzymatic primer extension with strand displacement offers a novel and prebiotically plausible approach to RNA self-replication.