Editors for Cancer Biology

We aim to publish conceptually important advances in all areas of cancer biology, including the discovery of new mechanisms responsible for cancer initiation, progression and therapy response. We are also interested in clinical trials or other clinical observations that reveal new and important biological insights. Read the latest research in this subject area.

Senior editors

  1. Utpal Banerjee

    University of California, Los Angeles, United States

    Utpal Banerjee is the Irving and Jean Stone Professor and Chair of the Department of Molecular, Cell and Developmental Biology at the University of California, Los Angeles, with a joint appointment in the Department of Biological Chemistry at the David Geffen School of Medicine. He also serves as Co-Director of the Broad Stem Cell Research Center and as Director of the UCLA Interdepartmental Minor in Biomedical Research. He is a member of UCLA’s Jonsson Comprehensive Cancer Center and is affiliated with the Brain Research Institute and the Neuroscience Graduate Program.

    Banerjee’s laboratory has worked on several oncogenic and metabolic signals that are important in development and disease. The lab studies the effects of systemic signals on the maintenance of blood progenitors in Drosophila, and the role of metabolic pathways in the control of proliferation and differentiation in the preimplantation mouse embryo.

    Expertise
    Developmental Biology
    Stem Cells and Regenerative Medicine
    Cancer Biology
    Research focus
    haematopoiesis
    cancer biology
    Experimental organism
    D. melanogaster
    mouse
  2. Eduardo Franco

    McGill University, Canada

    Eduardo Franco is Professor and Chairman, Department of Oncology, and Director, Division of Cancer Epidemiology, McGill University, Montreal. He holds BSc (1975) and Licentiate (1976) degrees in biology from Universidade de Campinas, Brazil, and master's (MPH) and doctoral (DrPH) degrees in public health microbiology from the University of North Carolina at Chapel Hill (1981-84). He was a Guest Researcher at the US Centers for Disease Control in Atlanta (1980-81 and 1983-84), and a post-doctoral fellow in cancer epidemiology during 1984 at the International Agency for Research on Cancer in Lyon, France, at the US National Cancer Institute (NCI) in Bethesda, and at Louisiana State University, in New Orleans. Since 1985, he has conducted epidemiologic research on the causes of cancer and on the means to prevent it or to improve patient survival. He is mostly known for his contributions to our understanding of human papillomavirus infection as the cause of cervical cancer and using this knowledge to prevent this cancer via vaccination and improved screening strategies. He received the Canadian Cancer Research Alliance’s Distinguished Service to Cancer Research Award, Lifetime Achievement Awards from the American Society for Colposcopy and Cervical Pathology and from the International Papillomavirus Society, the Women in US Government’s Leadership Award, the Canadian Cancer Society’s Warwick Prize, the Geoffrey Howe Outstanding Contribution Award from the Canadian Society for Epidemiology and Biostatistics, the University of British Columbia’s Chew Wei Memorial Prize in Cancer Research, and the McLaughlin-Gallie Award from the Royal College of Physicians of Canada. He has mentored 115 graduate students and post-doctoral fellows, and 30 undergraduate trainees. He is Officer of the Order of Canada and Fellow of the Royal Society of Canada and of the Canadian Academy of Health Sciences. Heholds an honorary doctorate from Universidade Fernando Pessoa, Porto, Portugal.

    Expertise
    Cancer Biology
    Epidemiology and Global Health
    Human Biology and Medicine
    Research focus
    molecular epidemiology and prevention of cervical cancer and human papillomavirus-associated diseases
    cancers of the upper aero-digestive tract
    prostate, endometrium, and childhood tumours
    efficacy of cancer screening strategies
    the impact of measurement error in epidemiology
    societal and clinical influences on cancer patient survival
    Competing interests statement
    Entire research program funded by the Medical Research Council of Canada (until 1999), Canadian Institutes of Health Research (CIHR) (1999-present), National Institutes of Health, Canadian Cancer Society, and Cancer Research Society. He has received salary awards from the Fonds de Recherche Quebec Santé and CIHR. He holds a James McGill Professorship and the Minda de Gunzburg Endowed Chair at McGill University. He serves as Editor-in-Chief for Preventive Medicine and Preventive Medicine Reports and serves on the editorial boards of Cancer Epidemiology, Biomarkers & Prevention, International Journal of Cancer, Papillomavirus Research, and Salud Publica de Mexico. He has served as occasional consultant to companies involved with HPV vaccination (Merck and GSK) and HPV diagnostics (Roche, Abbott, Qiagen, and BD).
  3. Maureen Murphy

    The Wistar Institute, United States

    Maureen E. Murphy, Ph.D., is a Professor and Program Leader in the Molecular and Cellular Oncogenesis Program of The Wistar Institute. Dr. Murphy joined Wistar in 2011 and became a Program Leader in early 2012. She is also an adjunct professor at Drexel University College of Medicine and The Perelman School of Medicine at the University of Pennsylvania. Previously, Dr. Murphy was a professor at the Fox Chase Cancer Center. Since 1999, she has received continuous support from the National Cancer Institute (NCI) for her research on the p53 tumor suppressor protein and the HSP70 molecular chaperone.

    A noted expert in the role of the p53 gene in cancer, Dr. Murphy’s laboratory focuses on how p53 functions to suppress tumor development. Through her lab’s work, Dr. Murphy is investigating the genetics of cancer health disparities. In efforts to improve precision medicine, her group is performing drug screens on tumor cells containing this variant, with the goal of finding drugs that will kill these cells preferentially. For her work on p53, Dr. Murphy is the recipient of the 2016 Gateway for Cancer Research Leadership in Cancer Advocacy Award. Murphy’s group also studies the stress-induced protein HSP70. With the knowledge that HSP70 is overexpressed in late stage cancers, Dr. Murphy’s group has pioneered the use of inhibitors of HSP70 for cancer therapy, particularly metastatic melanoma. For this effort, in 2014 her group won a Discovery Fast Track award from GlaxoSmithKline for the development of HSP70 inhibitors for cancer therapy.

    In addition to her research, Dr. Murphy also plays pivotal administrative roles as Wistar’s Associate Vice President for Faculty Affairs, the Principal Investigator of its Training Grant in Basic Cancer Research, the head of the Junior Faulty Mentoring program, and the Director of its Postdoctoral Training Program. A member of the NCI’s Cancer and Molecular Pathology (CAMP) federal grant review committee, Dr. Murphy has also reviewed grants for the New Jersey Commission for Cancer Research, the Department of Defense, and Alex’s Lemonade Stand Foundation for Pediatric Cancer Research.

    Dr. Murphy earned a Bachelor of Science degree in biochemistry at Rutgers University, followed by a doctorate in molecular biology at the University of Pennsylvania School of Medicine. In 1994, she began postdoctoral research at Princeton University in the laboratory of Arnold J. Levine, Ph.D., a co-discoverer of p53 and a pioneer in the field of tumor suppressor genes and cancer biology.

    Expertise
    Cancer Biology
    Research focus
    p53
    ferroptosis
    mitochondria
    colon cancer
    HSP70
    polymorphism
    Competing interests statement
    Maureen Murphy is a member of the American Association for Cancer Research (AACR). In addition to eLife, she holds editorial positions at Cancer Biology and Therapy (Senior Editor), Cancer Research (Senior Editor), Molecular Cancer Research and Carcinogenesis Integrative Research. She is a member of the NIH NCI Cancer and Molecular Pathology federal grant review committee, and receives federal funding from the National Institutes of Health (NIH).
  4. Päivi Ojala

    University of Helsinki, Finland
    Imperial College London, United Kingdom

    Päivi Ojala is the Professor of Cancer Cell Biology at University of Helsinki and Chair of Viral Tumorigenesis at Imperial College London. She has made significant contributions to the Kaposi’s Sarcoma herpesvirus (KSHV) field and has more recently focused also on the role of lymphatic endothelial microenvironment on cancer cell metastasis. She has expertise in organotypic 3D co-culture models, cell-based high-content screens, protein kinase signalling and viral technologies. Her work has led to demonstration of restoration of p53 function by small molecule inhibitors as a therapeutic modality for KSHV-induced lymphomas, identification of host Pim kinases, nucleophosmin, and the p53-p21 axis as novel regulators of viral replication, and shown that KSHV infection reprograms lymphatic endothelial cells (LECs) to a new, more invasive cell type. They have also demonstrated that LEC interaction with melanoma cells leads to increased distant organ metastasis in vivo, which is dependent on MMP14, Notch3 and b1-integrin- Dr. Ojala holds a doctoral degree in Molecular Genetics from the University of Helsinki, and has received postdoctoral training at the Yale School of Medicine, CT, USA.

    Expertise
    Cancer Biology
    Microbiology and Infectious Disease
    Research focus
    human tumor viruses
    virus-host interactions
    tumor microenvironment
    metastasis
    Competing interests statement
    Päivi Ojala receives funding from the Academy of Finland, Sigrid Juselius Foundation, Cancer Foundation Finland and University of Helsinki.
  5. Jeffrey Settleman

    Pfizer, United States

    Jeff Settleman is Senior Vice President and Group Head of Oncology Research and Development at Pfizer. Before joining Pfizer, Dr. Settleman was Head of Oncology Research at Calico Life Sciences, an aging-focused biotechnology company in South San Francisco. His research is focused on cancer cell biology and therapeutics. He is particularly interested in mechanisms of drug resistance and the phenotypic heterogeneity within cell populations that drives tumor evolution. He received a Ph.D. degree in Genetics from Yale University in 1989, conducting thesis research under the mentorship of Dr. Dan Dimaio, and from 1989-1992 was a postdoctoral fellow at the Whitehead Institute for Biomedical Research at M.I.T. in Dr. Robert Weinberg’s laboratory. He joined the Harvard School of Medicine faculty in 1992, and was named the Laurel Schwartz Professor of Oncology at Harvard Medical School in 2008. He was also the Director of the Center for Molecular Therapeutics, the Scientific Director of the Massachusetts General Hospital Cancer Center, and the Leader of the Cancer Cell Biology program within the Dana Farber/Harvard Cancer Center. In 2010, Dr. Settleman transitioned from academia to industry, joining Genentech as the Senior Director of Discovery Oncology, where he oversaw efforts to identify and validate targets for oncology drug discovery and to discover predictive biomarkers for new cancer therapies.

    Expertise
    Cancer Biology
    Research focus
    cancer cell biology
    signal transduction
    tumor heterogeneity
    signaling
    epigenetics
  6. Richard M White

    Memorial Sloan Kettering Cancer Center, United States

    Richard White, M.D., Ph.D, is a physician-scientist at the Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College. He is interested in basic mechanisms underlying metastasis, using the zebrafish as a model system. His work has established numerous techniques for cancer modeling and high-resolution imaging in the fish. Using these tools, the lab is focused on the cross-talk between tumor cells and the microenvironment, and how this interplay influences metastatic success. His work has revealed novel interactions between melanoma cells and adipocytes in the microenvironment, and how neural crest programs play roles in melanoma progression. He has been awarded the NIH Director’s New Innovator Award, the Pershing Square Foundation Award, and the Mark Foundation ASPIRE award.

    Expertise
    Cancer Biology
    Developmental Biology
    Research focus
    metastasis
    melanocyte development
    neural crest
    melanoma
    adipocytes
    microenvironment
    melanocytes
    Experimental organism
    zebrafish
    Competing interests statement
    Richard White receives funding from the National Institutes of Health, the Pershing Square Sohn Foundation, the Mark Foundation, the Melanoma Research Alliance, the American Cancer Society and the Harry J. Lloyd Foundation. He receives consulting fees from N-of-One, Inc.

Reviewing editors

  1. Frederic A Bard

    Institute of Molecular and Cell Biology, Singapore, Singapore

    Expertise
    Cell Biology
    Cancer Biology
    Research focus
    golgi
    protein glycosylation
    signaling
    cancer
    matrix degradation
    cell migration
    Experimental organism
    human
    mouse
  2. Xuetao Cao

    Zhejiang University School of Medicine, China

    Expertise
    Cancer Biology
    Immunology and Inflammation
    Research focus
    immunology of APCs
    TLR signalling and immune regulation
    cancer immunotherapy and gene therapy
  3. Irwin Davidson

    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Chromosomes and Gene Expression
    Research focus
    transcription
    chromatin
    genomics
    cancer
    Experimental organism
    human
    mouse
  4. Ralph J DeBerardinis

    University of Texas Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    metabolism
    cancer
    genetics
    medicine
    pediatrics
    genomics
    mitochondria
    Experimental organism
    human
    mouse
  5. Martin Eilers

    University of Würzburg, Germany

    Expertise
    Cancer Biology
    Research focus
    Myc proteins
    Myc function
    Targeting N-MYC/AURORA for tumor therapy
    Myc and Ubiquitin
    Experimental organism
    human
  6. Joaquin Espinosa

    University of Colorado Anschutz Medical Campus, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    cancer biology
    apoptosis
    p53
    tumor suppressors
    trisomy 21
    Down syndrome
    gene expression
    chromatin
  7. Lydia W S Finley

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cell Biology
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Research focus
    cell metabolism
    cancer
    stem cells
    epigenetics
    cell fate
  8. Margaret Frame

    University of Edinburgh, United Kingdom

    Expertise
    Cancer Biology
    Research focus
    cancer
    cell adhesion networks
    nodal tyrosine kinases
  9. Christine M Friedenreich

    University of Calgary, Canada

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Epidemiology and Global Health
    Research focus
    cancer epidemiology
    cancer etiology
    cancer prevention
    physical activity
    obesity
    diet
    biologic mechanisms
  10. Michael R Green

    University of Massachusetts Medical School, United States

    Expertise
    Cancer Biology
    Chromosomes and Gene Expression
    Human Biology and Medicine
    Research focus
    transcription
    pre-mRNA splicing
    cancer molecular biology
    oncology
    genetics
    functional genomics
    Experimental organism
    human
    mouse
    S. cerevisiae
  11. William C Hahn

    Dana-Farber Cancer Institute, United States

    Expertise
    Cancer Biology
    Genetics and Genomics
    Human Biology and Medicine
    Research focus
    cancer
    transformation
    functional genomics
    RAS
    YAP1
    Experimental organism
    human
  12. Matthew G. Vander Heiden

    Massachusetts Institute of Technology, United States

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    cancer biology
    biochemistry
    metabolism
    tumor microenvironment
    redox biology
    Experimental organism
    mouse
    human
  13. Wenwei Hu

    Rutgers University, United States

    Expertise
    Cancer Biology
    Research focus
    p53 signaling
    tumor suppressors
    cancer metabolism
    cancer cell biology
    signal transduction
    Experimental organism
    human
    mouse
  14. Tony Hunter

    Salk Institute for Biological Studies, United States

    Expertise
    Cancer Biology
    Cell Biology
    Research focus
    cancer
    signal transduction
    phosphorylation
    ubiquitylation
    sumoylation
    Experimental organism
    mouse
    yeast
  15. Gou Young Koh

    Institute of Basic Science and Korea Advanced Institute of Science and Technology (KAIST), South Korea

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Developmental Biology
    Research focus
    angiogenesis
    lymphangiogenesis
    adipogenesis
    cardiogenesis
    vascular and cardiovascular biology
  16. Ashish Lal

    National Institutes of Health, United States

    Expertise
    Cancer Biology
    Biochemistry and Chemical Biology
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    RNA biology
    lncRNAs
    microRNAs
    gene regulation
    cancer biology
    p53
    DNA damage
    Experimental organism
    human
  17. Ross Levine

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Research focus
    genetic basis of blood disorders
    myeloid malignancies
    myeloproliferative neoplasms
    leukemia
    Experimental organism
    human
  18. Beate Lichtenberger

    Medical University of Vienna, Austria

    Expertise
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Research focus
    Cancer-associated fibroblasts (CAFs)
    fibroblast-mediated skin pathologies
    skin cancer
    stem cell fate decisions
    Experimental organism
    human
    mouse
  19. Yuting Ma

    Suzhou Institute of Systems Medicine, China

    Expertise
    Cancer Biology
    Immunology and Inflammation
    Cell Biology
    Research focus
    tumor immunology
    immunotherapy
    tumor microenvironment
    stress responses
    neuroendocrine-immune crosstalk
    cell death
  20. Kay F Macleod

    University of Chicago, United States

    Expertise
    Cell Biology
    Cancer Biology
    Research focus
    cell death pathways
    mitochondria
    autophagy in breast cancer
  21. Ravindra Majeti

    Stanford University, United States

    Expertise
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Research focus
    stem cells
    hematopoietic stem cells
    acute myeloid leukemia
    xenotransplantation
    pre-leukemia
    Experimental organism
    human
  22. Grant McArthur

    Peter MacCallum Cancer Centre, Australia

    Expertise
    Cancer Biology
    Research focus
    melanoma
  23. Martin McMahon

    University of Utah, United States

    Expertise
    Cancer Biology
    Research focus
    metastatic melanoma
    lung cancer
    thyroid cancer
    Experimental organism
    mouse
    human
  24. Duojia Pan

    UT Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    growth control
    tumor suppressors
    oncogenes
    Hippo signaling
    transcription
    regeneration
    Experimental organism
    D. melanogaster
    mouse
  25. Lynne-Marie Postovit

    University of Alberta, Canada

    Expertise
    Cancer Biology
    Cell Biology
    Stem Cells and Regenerative Medicine
    Research focus
    cellular plasticity
    tumour microenvironment
    hypoxia
    stem cells
    metastasis
    ovarian cancer
    breast cancer
  26. Daniela Robles-Espinoza

    International Laboratory for Human Genome Research, Mexico

    Expertise
    Cancer Biology
    Genetics and Genomics
    Research focus
    melanoma
    bioinformatics
    telomeres
    acral lentiginous melanoma
    sequencing
  27. Jody Rosenblatt

    King's College London, United Kingdom

    Expertise
    Cell Biology
    Human Biology and Medicine
    Cancer Biology
    Research focus
    apoptosis
    mitosis
    cell extrusion
    epithelial
    homeostasis
    morphogenesis
    cancer cell biology
  28. Charles Sawyers

    Memorial Sloan-Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    oncology and translational medicine
    oncology
    translational medicine
    Experimental organism
    human
  29. Nima Sharifi

    Cleveland Clinic, United States

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Research focus
    steroid biochemistry
    steroid metabolism
    prostate cancer
    nuclear receptors
    hormone therapy resistance
    androgens
    oncology
    Experimental organism
    mouse
  30. Xiaobing Shi

    Van Andel Institute, United States

    Expertise
    Chromosomes and Gene Expression
    Cancer Biology
    Research focus
    epigenetics
    histone modifications
    transcription
    methylation
    acetylation
    YEATS domain
    PHD finger
    ZZ domain
    Experimental organism
    mouse
    cancer cell lines
  31. Margaret Stanley

    University of Cambridge, United Kingdom

    Expertise
    Cancer Biology
    Microbiology and Infectious Disease
    Human Biology and Medicine
    Epidemiology and Global Health
    Research focus
    vaccines
    cervix cancer
    cervix precancer
    keratinocyte biology
    human papillomavirus
    DNA viruses
    vaccine immunology
    Experimental organism
    human
  32. Ivan Topisirovic

    Jewish General Hospital, Canada

    Expertise
    Cancer Biology
    Chromosomes and Gene Expression
    Cell Biology
    Research focus
    protein synthesis
    mRNA translation
    signal transduction
    post-transcriptional regulation of gene expression
    metabolism
  33. Alfonso Valencia

    Barcelona Supercomputing Center, Spain

    Expertise
    Cancer Biology
    Computational and Systems Biology
    Research focus
    bioinformatics
    computational biology
    structural bioinformatics
    co-evolution
    cancer genomics
    text mining
  34. Hao Zhu

    University of Texas Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Human Biology and Medicine
    Research focus
    mechanisms of tissue repair and organ regeneration
    liver cancer
    hepatocellular carcinoma
    epigenetics
    polyploidy
    Experimental organism
    human
    mouse
  35. Wilbert Zwart

    Netherlands Cancer Institute, Netherlands

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    breast cancer
    prostate cancer
    hormonal regulation
    epigenetics
    transcription factors
    genomic profiling
    Experimental organism
    human