Editors for Cancer Biology
Senior editors
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Eduardo Franco
McGill University, Canada
Eduardo Franco is Professor and Chairman, Department of Oncology, and Director, Division of Cancer Epidemiology, McGill University, Montreal. He holds BSc (1975) and Licentiate (1976) degrees in biology from Universidade de Campinas, Brazil, and master's (MPH) and doctoral (DrPH) degrees in public health microbiology from the University of North Carolina at Chapel Hill (1981-84). He was a Guest Researcher at the US Centers for Disease Control in Atlanta (1980-81 and 1983-84), and a post-doctoral fellow in cancer epidemiology during 1984 at the International Agency for Research on Cancer in Lyon, France, at the US National Cancer Institute (NCI) in Bethesda, and at Louisiana State University, in New Orleans. Since 1985, he has conducted epidemiologic research on the causes of cancer and on the means to prevent it or to improve patient survival. He is mostly known for his contributions to our understanding of human papillomavirus infection as the cause of cervical cancer and using this knowledge to prevent this cancer via vaccination and improved screening strategies. He received the Canadian Cancer Research Alliance’s Distinguished Service to Cancer Research Award, Lifetime Achievement Awards from the American Society for Colposcopy and Cervical Pathology and from the International Papillomavirus Society, the Women in US Government’s Leadership Award, the Canadian Cancer Society’s Warwick Prize, the Geoffrey Howe Outstanding Contribution Award from the Canadian Society for Epidemiology and Biostatistics, the University of British Columbia’s Chew Wei Memorial Prize in Cancer Research, and the McLaughlin-Gallie Award from the Royal College of Physicians of Canada. He has mentored 115 graduate students and post-doctoral fellows, and 30 undergraduate trainees. He is Officer of the Order of Canada and Fellow of the Royal Society of Canada and of the Canadian Academy of Health Sciences. Heholds an honorary doctorate from Universidade Fernando Pessoa, Porto, Portugal.
- Expertise
- Epidemiology and Global Health
- Cancer Biology
- Microbiology and Infectious Disease
- Research focus
- molecular epidemiology and prevention of cervical cancer and human papillomavirus-associated diseases
- cancers of the upper aero-digestive tract
- prostate, endometrium, and childhood tumours
- efficacy of cancer screening strategies
- the impact of measurement error in epidemiology
- societal and clinical influences on cancer patient survival
- Competing interests statement
- Entire research program funded by the Medical Research Council of Canada (until 1999), Canadian Institutes of Health Research (CIHR) (1999-present), National Institutes of Health, Canadian Cancer Society, and Cancer Research Society. He has received salary awards from the Fonds de Recherche Quebec Santé and CIHR. He holds a James McGill Professorship and the Minda de Gunzburg Endowed Chair at McGill University. He serves as Editor-in-Chief for Preventive Medicine and Preventive Medicine Reports and serves on the editorial boards of Cancer Epidemiology, Biomarkers & Prevention, International Journal of Cancer, Papillomavirus Research, and Salud Publica de Mexico. He has served as occasional consultant to companies involved with HPV vaccination (Merck and GSK) and HPV diagnostics (Roche, Abbott, Qiagen, and BD).
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Sean Morrison
Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, United States
The Morrison laboratory studies the cellular and molecular mechanisms that regulate stem cell function in the nervous and hematopoietic systems. Dr Morrison obtained his BSc in biology and chemistry from Dalhousie University (1991), then completed a PhD in immunology at Stanford University (1996), and a postdoctoral fellowship in neurobiology at Caltech (1999). From 1999 to 2011, Dr Morrison was at the University of Michigan where he Directed their Center for Stem Cell Biology. Recently, Dr Morrison moved to the University of Texas Southwestern Medical Center where he is the founding Director of the new Children’s Research Institute. Dr Morrison’s laboratory studies the mechanisms that regulate stem cell self-renewal and stem cell aging, as well as the role these mechanisms play in cancer. Dr Morrison was a Searle Scholar (2000–2003), was named in Technology Review Magazine’s list of 100 young innovators (2002), received the Presidential Early Career Award for Scientists and Engineers (2003), the International Society for Hematology and Stem Cell’s McCulloch and Till Award (2007), the American Association of Anatomists Harland Mossman Award (2008), and a MERIT Award from the National Institute on Aging. Dr Morrison has also been active in public policy issues surrounding stem cells. For example, he has twice testified before Congress and was a leader in the successful “Proposal 2” campaign to protect stem cell research in Michigan’s state constitution.
- Expertise
- Cancer Biology
- Stem Cells and Regenerative Medicine
- Research focus
- cancer biology
- tissue stem cells
- hematopoietic system
- blood
- Competing interests statement
- Sean Morrison receives funding from the Howard Hughes Medical Institute, the National Institutes of Health, and the Cancer Prevention and Research Institute of Texas. In addition to being a Senior editor for eLife, he is a member of the editorial boards of Cell Stem Cell, the Journal of Experimental Medicine, the EMBO Journal, the Faculty of 1000, Current Opinion in Cell Biology, Cancer Cell, EMBO Reports, and Stem Cell Reports. He serves on the scientific advisory boards of the California Institute for Regenerative Medicine, the University of Washington Institute for Stem Cells and Regenerative Medicine, the University of California, Los Angeles Broad Stem Cell Research Center, and the Common Fund for the National Institutes of Health Center for Regenerative Medicine. He is President-Elect of the International Society for Stem Cell Research. He is a co-founder and shareholder in OncoMed Pharmaceuticals, a consultant and shareholder in G1 Therapeutics, a shareholder in Fate Therapeutics, and a consultant for Molecular Devices.
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Jeffrey Settleman
Calico Life Sciences, United States
Jeff Settleman is the Head of Oncology Research at Calico Life Sciences, an aging-focused biotechnology company in South San Francisco. His research is focused on cancer cell biology and therapeutics. He is particularly interested in mechanisms of drug resistance and the phenotypic heterogeneity within cell populations that drives tumor evolution. He received a Ph.D. degree in Genetics from Yale University in 1989, conducting thesis research under the mentorship of Dr. Dan Dimaio, and from 1989-1992 was a postdoctoral fellow at the Whitehead Institute for Biomedical Research at M.I.T. in Dr. Robert Weinberg’s laboratory. He joined the Harvard School of Medicine faculty in 1992, and was named the Laurel Schwartz Professor of Oncology at Harvard Medical School in 2008. He was also the Director of the Center for Molecular Therapeutics, the Scientific Director of the Massachusetts General Hospital Cancer Center, and the Leader of the Cancer Cell Biology program within the Dana Farber/Harvard Cancer Center. In 2010, Dr. Settleman transitioned from academia to industry, joining Genentech as the Senior Director of Discovery Oncology, where he oversaw efforts to identify and validate targets for oncology drug discovery and to discover predictive biomarkers for new cancer therapies.
- Expertise
- Cancer Biology
- Research focus
- cancer cell biology
- signal transduction
- tumor heterogeneity
- signaling
- epigenetics
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Maarten van Lohuizen
The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Netherlands
Maarten van Lohuizen received his PhD at the NKI/University of Amsterdam in 1992 studying cooperating oncogenes with Anton Berns. After a postoc at the University of California, San Francisco, he started his lab at the NKI in 1995 and heads the Division of Molecular Genetics. He also is a professor at the University of Amsterdam Medical Center, department Clinical Genetics & Oncogenomics, focusing on epigenetics and stem cells. Maarten studies epigenetic master switches that control cell and tissue development, and how these go awry in cancer. Specifically, his group focuses on the mechanism of stable inherited transcriptional repression by Polycomb group proteins and the effects of deregulation of Polycomb genes on development, cell cycle control, cancer formation and stem cell maintenance. Current focus is on Glioblastoma, non-small cell lung cancer and mesothelioma, using state of the art mouse models and genetic screening and drug screening to find new effective epigenetic drug combinations to target these cancers. Maarten was elected as European Molecular Biology Organization (EMBO) member (2004); Member of Academia Europaea (2015) and Member of the Oncode Institute (2017).
- Expertise
- Cancer Biology
- Stem Cells and Regenerative Medicine
- Research focus
- epigenetics
- cancer biology
- stem cells
- chromatin
- Polycomb group proteins
- Competing interests statement
- Maarten van Lohuizen receives funding from The Dutch Cancer Society (KWF), the Netherlands Organization of Scientific research (NWO), The Gravity program, Cancer Genomics Centre Netherlands (CGC.nl), the European Research Council and the Oncode Institute. He is editorial board member of Current Opinion in Genetics & Development, Epigenetics & Chromatin, Stem Cell reports and the Faculty of 1000.
Reviewing editors
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Utpal Banerjee
University of California, Los Angeles, United States
- Expertise
- Cancer Biology
- Stem Cells and Regenerative Medicine
- Human Biology and Medicine
- Developmental Biology
- Research focus
- haematopoiesis
- cancer biology
- Experimental organism
- Drosophila
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Xuetao Cao
Zhejiang University School of Medicine, China
- Expertise
- Cancer Biology
- Immunology and Inflammation
- Research focus
- immunology of APCs
- TLR signalling and immune regulation
- cancer immunotherapy and gene therapy
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Irwin Davidson
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Chromosomes and Gene Expression
- Research focus
- transcription
- chromatin
- genomics
- cancer
- Experimental organism
- human
- mouse
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Ralph J DeBerardinis
University of Texas Southwestern Medical Center, United States
- Expertise
- Cancer Biology
- Cell Biology
- Human Biology and Medicine
- Research focus
- cancer
- metabolism
- metabolic pathways
- medicine
- genetics
- Experimental organism
- human
- mouse
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Elisabetta Dejana
FIRC Institute of Molecular Oncology, Italy
- Expertise
- Cancer Biology
- Cell Biology
- Developmental Biology
- Research focus
- angiogenesis
- cell adhesion
- VE-cadherin
- vascular permeability
- vascular development and patterning
- endothelium
- blood brain barrier
- Experimental organism
- mouse
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Martin Eilers
University of Würzburg, Germany
- Expertise
- Cancer Biology
- Research focus
- Myc proteins
- Myc function
- Targeting N-MYC/AURORA for tumor therapy
- Myc and Ubiquitin
- Experimental organism
- human
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Joaquin Espinosa
University of Colorado Anschutz Medical Campus, United States
- Expertise
- Cancer Biology
- Cell Biology
- Human Biology and Medicine
- Research focus
- cancer biology
- apoptosis
- p53
- tumor suppressors
- trisomy 21
- Down syndrome
- gene expression
- chromatin
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Margaret Frame
University of Edinburgh, United Kingdom
- Expertise
- Cancer Biology
- Research focus
- cancer
- cell adhesion networks
- nodal tyrosine kinases
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Michael R Green
University of Massachusetts Medical School, United States
- Expertise
- Cancer Biology
- Chromosomes and Gene Expression
- Human Biology and Medicine
- Research focus
- transcription
- pre-mRNA splicing
- cancer molecular biology
- oncology
- genetics
- functional genomics
- Experimental organism
- human
- mouse
- S. cerevisiae
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Matthew G. Vander Heiden
Massachusetts Institute of Technology, United States
- Expertise
- Cancer Biology
- Human Biology and Medicine
- Research focus
- cancer metabolism
- cell metabolism
- metabolic biochemistry
- Experimental organism
- mouse
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Tony Hunter
Salk Institute for Biological Studies, United States
- Expertise
- Cancer Biology
- Cell Biology
- Research focus
- cell signaling and basic cancer biology
- signaling pathways in animal and human cells
- cell cycle
- phosphorylation
- protein modification
- cancer
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Gou Young Koh
Institute of Basic Science and Korea Advanced Institute of Science and Technology (KAIST), South Korea
- Expertise
- Cancer Biology
- Human Biology and Medicine
- Developmental Biology
- Research focus
- angiogenesis
- lymphangiogenesis
- adipogenesis
- cardiogenesis
- vascular and cardiovascular biology
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Ross Levine
Memorial Sloan Kettering Cancer Center, United States
- Expertise
- Cancer Biology
- Research focus
- genetic basis of blood disorders
- myeloid malignancies
- myeloproliferative neoplasms
- leukemia
- Experimental organism
- human
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Beate Lichtenberger
Medical University of Vienna, Austria
- Expertise
- Cancer Biology
- Stem Cells and Regenerative Medicine
- Research focus
- Cancer-associated fibroblasts (CAFs)
- fibroblast-mediated skin pathologies
- skin cancer
- stem cell fate decisions
- Experimental organism
- human
- mouse
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Ravindra Majeti
Stanford University, United States
- Expertise
- Cancer Biology
- Stem Cells and Regenerative Medicine
- Research focus
- hematopoietic stem cell function
- leukemia
- Experimental organism
- human
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Joan Massagué
Memorial Sloan Kettering Cancer Center, United States
- Expertise
- Cancer Biology
- Cell Biology
- Human Biology and Medicine
- Research focus
- cell signalling
- cell fate
- tumor heterogeneity
- metastasis
- Experimental organism
- human tissue
- mouse
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Martin McMahon
University of Utah, United States
- Expertise
- Cancer Biology
- Research focus
- metastatic melanoma
- lung cancer
- thyroid cancer
- Experimental organism
- mouse
- human
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Maureen Murphy
The Wistar Institute, United States
- Expertise
- Cancer Biology
- Research focus
- p53
- genetics
- ferroptosis
- cell death
- melanoma
- heat shock proteins
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Paivi Ojala
University of Helsinki, Finland
- Expertise
- Cancer Biology
- Research focus
- cancer biology
- tumor microenvironment
- virus-host cell interactions
- virus-induced oncogenesis
- Experimental organism
- human
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Duojia Pan
UT Southwestern Medical Center, United States
- Expertise
- Cancer Biology
- Cell Biology
- Human Biology and Medicine
- Research focus
- signal transduction
- growth control
- cancer biology
- Experimental organism
- Drosophila
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Jody Rosenblatt
University of Utah, United States
- Expertise
- Cell Biology
- Human Biology and Medicine
- Cancer Biology
- Research focus
- apoptosis
- mitosis
- cell extrusion
- epithelial
- homeostasis
- morphogenesis
- cancer cell biology
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Charles Sawyers
Memorial Sloan-Kettering Cancer Center, United States
- Expertise
- Cancer Biology
- Human Biology and Medicine
- Research focus
- oncology and translational medicine
- oncology
- translational medicine
- Experimental organism
- human
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Nima Sharifi
Cleveland Clinic, United States
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Research focus
- prostate cancer
- androgens
- steroid metabolism
- hormonal therapy
- androgen receptor
- Experimental organism
- human
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Xiaobing Shi
Van Andel Institute, United States
- Expertise
- Chromosomes and Gene Expression
- Cancer Biology
- Research focus
- cancer epigenetics
- chromatin
- post-translational modifications of histones
- gene expression
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Alfonso Valencia
Barcelona Supercomputing Center, Spain
- Expertise
- Cancer Biology
- Computational and Systems Biology
- Research focus
- bioinformatics
- computational biology
- structural bioinformatics
- co-evolution
- cancer genomics
- text mining
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Richard M White
Memorial Sloan Kettering Cancer Center, United States
- Expertise
- Cancer Biology
- Developmental Biology
- Stem Cells and Regenerative Medicine
- Research focus
- cancer
- metastasis
- genetics
- melanocyte
- melanoma
- neural crest
- Experimental organism
- human
- zebrafish
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Wilbert Zwart
Netherlands Cancer Institute, Netherlands
- Expertise
- Cancer Biology
- Human Biology and Medicine
- Research focus
- breast cancer
- prostate cancer
- hormonal regulation
- epigenetics
- transcription factors
- genomic profiling
- Experimental organism
- human
