Editors for Cancer Biology

We aim to publish conceptually important advances in all areas of cancer biology, including the discovery of new mechanisms responsible for cancer initiation, progression and therapy response. We are also interested in clinical trials or other clinical observations that reveal new and important biological insights. Read the latest research in this subject area.

Senior editors

  1. Sean Morrison

    Sean Morrison

    Senior Editor

    The Morrison laboratory studies the cellular and molecular mechanisms that regulate stem cell function in the nervous and hematopoietic systems. Dr Morrison obtained his BSc in biology and chemistry from Dalhousie University (1991), then completed a PhD in immunology at Stanford University (1996), and a postdoctoral fellowship in neurobiology at Caltech (1999). From 1999 to 2011, Dr Morrison was at the University of Michigan where he Directed their Center for Stem Cell Biology. Recently, Dr Morrison moved to the University of Texas Southwestern Medical Center where he is the founding Director of the new Children’s Research Institute. Dr Morrison’s laboratory studies the mechanisms that regulate stem cell self-renewal and stem cell aging, as well as the role these mechanisms play in cancer. Dr Morrison was a Searle Scholar (2000–2003), was named in Technology Review Magazine’s list of 100 young innovators (2002), received the Presidential Early Career Award for Scientists and Engineers (2003), the International Society for Hematology and Stem Cell’s McCulloch and Till Award (2007), the American Association of Anatomists Harland Mossman Award (2008), and a MERIT Award from the National Institute on Aging. Dr Morrison has also been active in public policy issues surrounding stem cells. For example, he has twice testified before Congress and was a leader in the successful “Proposal 2” campaign to protect stem cell research in Michigan’s state constitution.

    Expertise
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Research focus
    tissue stem cells
    blood
    cancer biology
    hematopoietic system
    Competing interests statement
    Sean Morrison receives funding from the Howard Hughes Medical Institute, the National Institutes of Health, and the Cancer Prevention and Research Institute of Texas. In addition to being a Senior editor for eLife, he is a member of the editorial boards of Cell Stem Cell, the Journal of Experimental Medicine, the EMBO Journal, the Faculty of 1000, Current Opinion in Cell Biology, Cancer Cell, EMBO Reports, and Stem Cell Reports. He serves on the scientific advisory boards of the California Institute for Regenerative Medicine, the University of Washington Institute for Stem Cells and Regenerative Medicine, the University of California, Los Angeles Broad Stem Cell Research Center, and the Common Fund for the National Institutes of Health Center for Regenerative Medicine. He is President-Elect of the International Society for Stem Cell Research. He is a co-founder and shareholder in OncoMed Pharmaceuticals, a consultant and shareholder in G1 Therapeutics, a shareholder in Fate Therapeutics, and a consultant for Molecular Devices.
  2. Aviv Regev

    Aviv Regev

    Senior Editor

    Aviv Regev is a computational biologist who joined the Broad Institute as a core member and MIT as a faculty member in 2006. Her work investigates how complex molecular networks function and evolve in the face of genetic and environmental changes, over time-scales ranging from minutes to millions of years. Regev received her MSc from Tel Aviv University, studying biology, computer science, and mathematics in the Interdisciplinary Program for the Fostering of Excellence, where she undertook research in both theoretical and experimental biology. She received her PhD in computational biology from Tel Aviv University. Prior to joining the Broad Institute, Regev was a fellow at the Bauer Center for Genomics Research at Harvard University, where she developed new approaches to the reconstruction of regulatory networks and modules from genomic data. Regev is also an associate professor in the Department of Biology at MIT
and director of the Klarman Cell Observatory at the Broad. Regev is the Director of the Cell Circuits Program at the Broad and a lead principal investigator for the Center for Cell Circuits at the Broad Institute, a Center of Excellence in Genomic Science (CEGS). Regev has been a Howard Hughes Medical Institute (HHMI) Early Career Scientist since 2009, and was named a Howard Hughes Medical Institute (HHMI) Investigator in 2013. She is a recipient of the NIH Director’s Pioneer Award, a Sloan fellowship from the Sloan Foundation, the Overton Prize from the International Society for Computational Biology, and the Earl and Thressa Stadtman Scholar Award from the American Society for Biochemistry and Molecular Biology (ASBMB).

    (Image Credit: Maria Nemchuk)

    Expertise
    Computational and Systems Biology
    Genetics and Genomics
    Chromosomes and Gene Expression
    Evolutionary Biology
    Cancer Biology
    Research focus
    systems biology
    molecular networks
    computational biology
    single cell genomics
    regulatory networks
    systems immunology
    gene regulation
    evolution
    Competing interests statement
    Aviv Regev receives funding from the Howard Hughes Medical Institute, the National Institutes of Health, and the Sloan Foundation. She is on the external advisory board of the San Diego Center for Systems Biology, the FAS Center for Systems Biology at Harvard, the Simons Institute for the Theory of Computing, the Jackson Laboratory, the European Molecular Biology Lab (EMBL), the SciLife Lab in Sweden, and ThermoFisher Scientific. She is on the advisory editorial board of Molecular Systems Biology and is an editorial board member of Genome Biology and Development. Regev is a consultant for Syros Phramaceuticals, GenePeeks, and CTIG (Cancer Therapeutics Innovation Group). Regev also worked for several years in the biotech industry in Israel, where she established and directed a bioinformatics research and development team at QBI, a functional genomics company.
  3. Charles Sawyers

    Charles Sawyers

    Senior Editor

    Charles Sawyers is an Investigator of the Howard Hughes Medical Institute and the Director of the Human Oncology and Pathogenesis Program at Memorial Sloan-Kettering Cancer Center. His studies of BCR-ABL tyrosine kinase function in chronic myeloid leukemia, in collaboration with Brian Druker and Novartis, led to the development of the kinase inhibitor imatinib as primary therapy for CML. This was followed by his discovery that BCR-ABL kinase domain mutations confer imatinib resistance, and development of the second generation Abl kinase inhibitor dasatinib, in collaboration with Bristol Myers Squibb. Sawyers' current work in prostate cancer resulted in the novel antiandrogen enzalutamide (MDV3100), discovered in collaboration with University of California, Los Angeles chemist Michael Jung, which received FDA approval in 2012. Sawyers is a member of the National Academy of Sciences and the Institute of Medicine and co-recipient of the 2009 Lasker~DeBakey Clinical Medical Research Award.

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    oncology and translational medicine
    oncology
    translational medicine
    Competing interests statement
    Charles Sawyers receives research funding from the Howard Hughes Medical Institute, the National Cancer Institute, the Starr Cancer Consortium, Stand Up to Cancer, and the Prostate Cancer Foundation. He is President Elect of the American Association of Cancer Research and will serve as President from 2013–14. He is a Councilor of the American Association of Physicians (until 2017) and serves on the editorial boards of Cell and Cancer Cell, and as a scientific advisor to Agios, Aragon, Aveo, Housey Pharmaceuticals, Merck, Nextech, Pfizer, and Tracon.
  4. Jeffrey Settleman

    Senior Editor

    Jeff Settleman is the Head of Oncology Research at Calico Life Sciences, an aging-focused biotechnology company in South San Francisco. His research is focused on cancer cell biology and therapeutics. He is particularly interested in mechanisms of drug resistance and the phenotypic heterogeneity within cell populations that drives tumor evolution. He received a Ph.D. degree in Genetics from Yale University in 1989, conducting thesis research under the mentorship of Dr. Dan Dimaio, and from 1989-1992 was a postdoctoral fellow at the Whitehead Institute for Biomedical Research at M.I.T. in Dr. Robert Weinberg’s laboratory. He joined the Harvard School of Medicine faculty in 1992, and was named the Laurel Schwartz Professor of Oncology at Harvard Medical School in 2008. He was also the Director of the Center for Molecular Therapeutics, the Scientific Director of the Massachusetts General Hospital Cancer Center, and the Leader of the Cancer Cell Biology program within the Dana Farber/Harvard Cancer Center. In 2010, Dr. Settleman transitioned from academia to industry, joining Genentech as the Senior Director of Discovery Oncology, where he oversaw efforts to identify and validate targets for oncology drug discovery and to discover predictive biomarkers for new cancer therapies.

    Expertise
    Cancer Biology
    Research focus
    cancer cell biology
    signal transduction
    tumor heterogeneity
    signaling
    epigenetics

Reviewing editors

  1. Margaret Frame

    University of Edinburgh, United Kingdom

    Expertise
    Cancer Biology
    Research focus
    cancer
    cell adhesion networks
    nodal tyrosine kinases
  2. Martin Eilers

    University of Würzburg, Germany

    Expertise
    Cancer Biology
    Research focus
    Myc proteins
    Myc function
    Targeting N-MYC/AURORA for tumor therapy
    Myc and Ubiquitin
    Experimental organism
    human
  3. A. Thomas Look

    Dana-Farber Cancer Institute, United States

    Expertise
    Cancer Biology
    Chromosomes and Gene Expression
    Human Biology and Medicine
    Research focus
    neuroblastoma
    acute leukemia
    hematopoietic malignancies
    cancer genetics
    Experimental organism
    human
    mouse
    zebrafish
  4. Ian Tannock

    Princess Margaret Cancer Centre, Canada

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    clinical trials
    tumour microenvironment
    cancer therapy
    clinical resistance to drugs
    Experimental organism
    human
  5. Jody Rosenblatt

    University of Utah, United States

    Expertise
    Cell Biology
    Human Biology and Medicine
    Cancer Biology
    Research focus
    apoptosis
    mitosis
    cell extrusion
    epithelial
    homeostasis
    morphogenesis
    cancer cell biology
  6. Matthew G. Vander Heiden

    Massachusetts Institute of Technology, United States

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    cancer metabolism
    cell metabolism
    metabolic biochemistry
    Experimental organism
    mouse
  7. Beate Lichtenberger

    Medical University of Vienna, Austria

    Expertise
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Research focus
    Cancer-associated fibroblasts (CAFs)
    fibroblast-mediated skin pathologies
    skin cancer
    stem cell fate decisions
    Experimental organism
    human
    mouse
  8. Kari Alitalo

    University of Helsinki, Finland

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    cancer biology
    oncogenes
    angiogenesis
    vascular biology
  9. Utpal Banerjee

    University of California, Los Angeles, United States

    Expertise
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Human Biology and Medicine
    Developmental Biology
    Research focus
    haematopoiesis
    cancer biology
    Experimental organism
    Drosophila
  10. Xuetao Cao

    Zhejiang University School of Medicine, China

    Expertise
    Cancer Biology
    Immunology and Inflammation
    Research focus
    immunology of apcs
    TLR signalling and immune regulation
    cancer immunotherapy and gene therapy
  11. Irwin Davidson

    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Chromosomes and Gene Expression
    Research focus
    transcription
    chromatin
    cancer
  12. Ralph J DeBerardinis

    University of Texas Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    cancer
    metabolism
    medicine
    genetics
    Experimental organism
    human
    mouse
  13. Elisabetta Dejana

    FIRC Institute of Molecular Oncology, Italy

    Expertise
    Cancer Biology
    Cell Biology
    Developmental Biology
    Research focus
    angiogenesis
    cell adhesion
    VE-cadherin
    vascular permeability
    vascular development and patterning
    endothelium
    blood brain barrier
  14. Joaquin Espinosa

    University of Colorado Denver School of Medicine, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    apoptosis
    p53
    tumor suppressors
    cancer biology
  15. Eduardo Franco

    McGill University, Canada

    Expertise
    Cancer Biology
    Epidemiology and Global Health
    Human Biology and Medicine
    Microbiology and Infectious Disease
    Research focus
    human biology and medicine
    microbiology and infectious disease
    cancer epidemiology and prevention
    screening
    human papillomavirus infection
  16. Michael R Green

    University of Massachusetts Medical School, United States

    Expertise
    Cancer Biology
    Chromosomes and Gene Expression
    Human Biology and Medicine
    Research focus
    RNA splicing
    cancer molecular biology
  17. Tony Hunter

    Salk Institute for Biological Studies, United States

    Expertise
    Cancer Biology
    Cell Biology
    Research focus
    cell signaling and basic cancer biology
    signaling pathways in animal and human cells
    cell cycle
    phosphorylation
    protein modification
    cancer
  18. Ross Levine

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Research focus
    genetic basis of blood disorders
    myeloid malignancies
    myeloproliferative neoplasms
    leukemia
    Experimental organism
    human
  19. Joan Massagué

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    signaling
    cell fate
    tumor heterogeneity
    metastasis
    Experimental organism
    human tissue
  20. Martin McMahon

    University of Utah, United States

    Expertise
    Cancer Biology
    Research focus
    metastatic melanoma
    lung cancer
    thyroid cancer
    Experimental organism
    mouse
    human
  21. Maureen Murphy

    The Wistar Institute, United States

    Expertise
    Cancer Biology
    Research focus
    p53
    genetics
    ferroptosis
    cell death
    melanoma
    heat shock proteins
  22. Duojia Pan

    UT Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    signal transduction
    growth control
    cancer biology
    Experimental organism
    Drosophila
  23. Alfonso Valencia

    Barcelona Supercomputing Center, Spain

    Expertise
    Cancer Biology
    Computational and Systems Biology
    Research focus
    bioinformatics
    structural bioinformatics
    evodevo
    cancer genomics
    text mining
  24. Maarten van Lohuizen

    The Netherlands Cancer Institute, Netherlands

    Expertise
    Cancer Biology
    Research focus
    epigenetics
    cancer
    stem cells
    chromatin
  25. Richard White

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Developmental Biology
    Stem Cells and Regenerative Medicine
    Research focus
    cancer
    metastasis
    genetics
    melanocyte
    melanoma
    neural crest
    Experimental organism
    human
    zebrafish