People

The working scientists who serve as eLife editors, our early-career advisors, governing board, and our executive staff all work in concert to realise eLife’s mission to accelerate discovery

Senior editors

  1. Sean Morrison

    Sean Morrison

    Senior Editor

    The Morrison laboratory studies the cellular and molecular mechanisms that regulate stem cell function in the nervous and hematopoietic systems. Dr Morrison obtained his BSc in biology and chemistry from Dalhousie University (1991), then completed a PhD in immunology at Stanford University (1996), and a postdoctoral fellowship in neurobiology at Caltech (1999). From 1999 to 2011, Dr Morrison was at the University of Michigan where he Directed their Center for Stem Cell Biology. Recently, Dr Morrison moved to the University of Texas Southwestern Medical Center where he is the founding Director of the new Children’s Research Institute. Dr Morrison’s laboratory studies the mechanisms that regulate stem cell self-renewal and stem cell aging, as well as the role these mechanisms play in cancer. Dr Morrison was a Searle Scholar (2000–2003), was named in Technology Review Magazine’s list of 100 young innovators (2002), received the Presidential Early Career Award for Scientists and Engineers (2003), the International Society for Hematology and Stem Cell’s McCulloch and Till Award (2007), the American Association of Anatomists Harland Mossman Award (2008), and a MERIT Award from the National Institute on Aging. Dr Morrison has also been active in public policy issues surrounding stem cells. For example, he has twice testified before Congress and was a leader in the successful “Proposal 2” campaign to protect stem cell research in Michigan’s state constitution.

    Expertise
    Cancer Biology
    Developmental Biology and Stem Cells
    Human Biology and Medicine
    Research focus
    tissue stem cells
    blood
    cancer biology
    hematopoietic system
  2. Charles Sawyers

    Charles Sawyers

    Senior Editor

    Charles Sawyers is an Investigator of the Howard Hughes Medical Institute and the Director of the Human Oncology and Pathogenesis Program at Memorial Sloan-Kettering Cancer Center. His studies of BCR-ABL tyrosine kinase function in chronic myeloid leukemia, in collaboration with Brian Druker and Novartis, led to the development of the kinase inhibitor imatinib as primary therapy for CML. This was followed by his discovery that BCR-ABL kinase domain mutations confer imatinib resistance, and development of the second generation Abl kinase inhibitor dasatinib, in collaboration with Bristol Myers Squibb. Sawyers' current work in prostate cancer resulted in the novel antiandrogen enzalutamide (MDV3100), discovered in collaboration with University of California, Los Angeles chemist Michael Jung, which received FDA approval in 2012. Sawyers is a member of the National Academy of Sciences and the Institute of Medicine and co-recipient of the 2009 Lasker~DeBakey Clinical Medical Research Award.

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    oncology and translational medicine
    oncology
    translational medicine
  3. Kevin Struhl

    Kevin Struhl

    Senior Editor

    Kevin Struhl received a BS and MS from MIT, a PhD from Stanford University Medical School, and did postdoctoral work at the MRC Laboratory of Molecular Biology in Cambridge, UK. He has been in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School since 1982, was acting Chair from 1997–98, and has been the David Wesley Gaiser Professor since 1991. His research combines genetic, molecular, genomic, and evolutionary approaches to address a wide variety of fundamental questions about transcriptional regulatory mechanisms and chromatin structure in yeast. In addition, he is interested in elucidating transcriptional regulatory circuits that mediate the process of cellular transformation and the formation of cancer stem cells. He has authored or co-authored nearly 300 research articles and reviews, and is an ISI Highly Cited Researcher. He received the Eli Lilly Award in Microbiology and is a Distinguished Researcher at the Institute of Molecular Biology and Biotechnology in Crete. Dr. Struhl is a Fellow of the American Academy of Microbiology, the American Association for the Advancement of Science, the American Academy of Arts and Sciences, the National Academy of Sciences, and the National Academy of Medicine.

    Expertise
    Cancer Biology
    Genes and Chromosomes
    Research focus
    transcription mechanisms
    gene regulation
    chromatin
    mRNA decay
    biological function
    cellular transformation
    cancer stem cells

Reviewing editors

  1. Margaret Frame

    University of Edinburgh, United Kingdom

    Expertise
    Cancer Biology
    Research focus
    cancer
    cell adhesion networks
    nodal tyrosine kinases
  2. Martin Eilers

    University of Würzburg, Germany

    Expertise
    Cancer Biology
    Research focus
    Myc proteins
    Myc function
    Targeting N-MYC/AURORA for tumor therapy
    Myc and Ubiquitin
    Experimental organism
    human
  3. A. Thomas Look

    Dana-Farber Cancer Institute, United States

    Expertise
    Cancer Biology
    Genes and Chromosomes
    Human Biology and Medicine
    Research focus
    neuroblastoma
    acute leukemia
    hematopoietic malignancies
    cancer genetics
    Experimental organism
    human
    mouse
    zebrafish
  4. Ian Tannock

    Princess Margaret Cancer Centre, Canada

    Expertise
    Cancer Biology
    Research focus
    clinical trials
    tumour microenvironment
    cancer therapy
    clinical resistance to drugs
    Experimental organism
    human
  5. Jody Rosenblatt

    University of Utah, United States

    Expertise
    Cell Biology
    Human Biology and Medicine
    Cancer Biology
    Research focus
    apoptosis
    mitosis
    cell extrusion
    epithelial
    homeostasis
    morphogenesis
    cancer cell biology
  6. Kari Alitalo

    University of Helsinki, Finland

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    cancer biology
    oncogenes
    angiogenesis
    vascular biology
  7. Utpal Banerjee

    University of California, Los Angeles, United States

    Expertise
    Cancer Biology
    Developmental Biology and Stem Cells
    Human Biology and Medicine
    Research focus
    haematopoiesis
    cancer biology
    Experimental organism
    Drosophila
  8. Xuetao Cao

    Zhejiang University School of Medicine, China

    Expertise
    Cancer Biology
    Immunology
    Research focus
    immunology of apcs
    TLR signalling and immune regulation
    cancer immunotherapy and gene therapy
  9. Irwin Davidson

    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France

    Expertise
    Biochemistry
    Cancer Biology
    Genes and Chromosomes
    Research focus
    transcription
    chromatin
    cancer
  10. Ralph J DeBerardinis

    University of Texas Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    cancer
    metabolism
    medicine
    genetics
    Experimental organism
    human
    mouse
  11. Elisabetta Dejana

    FIRC Institute of Molecular Oncology, Italy

    Expertise
    Cancer Biology
    Cell Biology
    Developmental Biology and Stem Cells
    Research focus
    angiogenesis
    cell adhesion
    VE-cadherin
    vascular permeability
    vascular development and patterning
    endothelium
    blood brain barrier
  12. Joaquin Espinosa

    University of Colorado Denver School of Medicine, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    apoptosis
    p53
    tumor suppressors
    cancer biology
  13. Eduardo Franco

    McGill University, Canada

    Expertise
    Cancer Biology
    Epidemiology and Global Health
    Human Biology and Medicine
    Microbiology and Infectious Disease
    Research focus
    human biology and medicine
    microbiology and infectious disease
    cancer epidemiology and prevention
    screening
    human papillomavirus infection
  14. Richard J Gilbertson

    Cambridge Cancer Center, United Kingdom

    Expertise
    Cancer Biology
    Human Biology and Medicine
    Research focus
    tumor biology
    cancer stem cells
  15. Michael R Green

    University of Massachusetts Medical School, United States

    Expertise
    Cancer Biology
    Genes and Chromosomes
    Human Biology and Medicine
    Research focus
    RNA splicing
    cancer molecular biology
  16. Tony Hunter

    Salk Institute for Biological Studies, United States

    Expertise
    Cancer Biology
    Cell Biology
    Research focus
    cell signaling and basic cancer biology
    signaling pathways in animal and human cells
    cell cycle
    phosphorylation
    protein modification
    cancer
  17. Ross Levine

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Research focus
    genetic basis of blood disorders
    myeloid malignancies
    myeloproliferative neoplasms
    leukemia
    Experimental organism
    human
  18. Joan Massagué

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    signaling
    cell fate
    tumor heterogeneity
    metastasis
    Experimental organism
    human tissue
  19. Martin McMahon

    University of Utah, United States

    Expertise
    Cancer Biology
    Research focus
    metastatic melanoma
    lung cancer
    thyroid cancer
    Experimental organism
    mouse
    human
  20. Maureen Murphy

    The Wistar Institute, United States

    Expertise
    Cancer Biology
    Research focus
    p53
    genetics
    ferroptosis
    cell death
    melanoma
    heat shock proteins
  21. Duojia Pan

    UT Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Human Biology and Medicine
    Research focus
    signal transduction
    growth control
    cancer biology
    Experimental organism
    Drosophila
  22. Ali Shilatifard

    Northwestern University Feinberg School of Medicine, United States

    Expertise
    Biochemistry
    Cancer Biology
    Genes and Chromosomes
    Research focus
    chromatin
    ELLs
    P-TEFb
    pol II
    MLLs
    chromosomal translocations and leukemia
    enhancers
    gene expression
    transcription
    Experimental organism
    Drosophila
  23. Alfonso Valencia

    Barcelona Supercomputing Center, Spain

    Expertise
    Cancer Biology
    Computational and Systems Biology
    Research focus
    bioinformatics
    structural bioinformatics
    evodevo
    cancer genomics
    text mining
  24. Maarten van Lohuizen

    The Netherlands Cancer Institute, Netherlands

    Expertise
    Cancer Biology
    Research focus
    epigenetics
    cancer
    stem cells
    chromatin
  25. Richard White

    Memorial Sloan Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Developmental Biology and Stem Cells
    Research focus
    cancer
    metastasis
    genetics
    melanocyte
    melanoma
    neural crest
    Experimental organism
    human
    zebrafish