Cancer Biology

Cancer Biology

eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    FOXP2 confers oncogenic effects in prostate cancer

    Xiaoquan Zhu, Chao Chen ... Yanyang Zhao
    FOXP2, encoding a forkhead-box transcription factor regarded as vital to proper development of human speech, was revealed to have an oncogenic potential and activate MET signaling in prostate cancer.
    1. Cancer Biology
    2. Cell Biology

    Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics

    Timothy J. Walker, Eduardo Reyes-Alvarez ... Lois M. Mulligan
    1. Cancer Biology
    2. Cell Biology

    EPAC1 inhibition protects the heart from doxorubicin-induced toxicity

    Marianne Mazevet, Anissa Belhadef ... Eric Morel
    The inhibition of EPAC1, a cAMP-binding protein, appears as a potential therapeutic strategy to limit doxorubicin-induced cardiotoxicity without interfering with its antitumoral activity.
    1. Epidemiology and Global Health
    2. Medicine
    3. Cancer Biology

    Special Issue: The impact of the COVID-19 pandemic on cancer prevention, control, care and survivorship

    Edited by Eduardo Franco et al.
    Our latest Special Issue brings together research covering many different aspects of the impact of the COVID-19 pandemic on cancer outcomes across the globe.
    1. Cancer Biology
    2. Cell Biology

    Cancer Survivorship: Protecting the heart

    Joshua M Inglis, Arduino A Mangoni
    Blocking a protein known as EPAC1 may prevent the development of heart-related side effects caused by a chemotherapy drug.
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    1. Cancer Biology
    2. Computational and Systems Biology

    Spatial transformation of multi-omics data unlocks novel insights into cancer biology

    Mateo Sokač, Asbjørn Kjær ... Nicolai J Birkbak
    GENIUS provides a deep learning framework for multi-omics integration that transforms data into spatial images, using integrated gradients to reveal novel and critical cancer gene association.


    1. Cancer Biology
    2. Cell Biology

    Protecting the heart

    Joshua M Inglis, Arduino A Mangoni
    1. Cancer Biology

    Reproducibility in Cancer Biology

    Edited by Roger J Davis et al.

Senior editors

  1. Wafik S El-Deiry
    Brown University, United States
  2. Eduardo Franco
    McGill University, Canada
  3. Erica Golemis
    Fox Chase Cancer Center, United States
  4. See more editors