Cancer Biology

Cancer Biology

eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology
    2. Cell Biology

    Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

    Francesca Butera, Julia E Sero ... Chris Bakal
    A live imaging and computational approach reveals feedback loops involving F-actin dynamics that regulate the NF-κB transcription factor RELA.
    1. Cancer Biology

    The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization

    Thi Mong Quynh Pham, Thanh Nhan Nguyen ... Le Son Tran
    The integration of pHLA binding and pHLA-TCR analysis effectively improves the precision of insilico neoantigen prioritization, potentially enhancing personalized immunotherapies for colorectal cancer.
    1. Cancer Biology
    2. Evolutionary Biology

    The theory of massively repeated evolution and full identifications of Cancer Driving Nucleotides (CDNs)

    Lingjie Zhang, Tong Deng ... Chung-I Wu
    Revised
    Reviewed Preprint v2 Updated
    1. Cancer Biology
    2. Evolutionary Biology

    On the discovered Cancer Driving Nucleotides (CDNs)–Distributions across genes, cancer types and patients

    Lingjie Zhang, Tong Deng ... Haijun Wen
    Revised
    Reviewed Preprint v2 Updated
    1. Cancer Biology

    A Large-Scale Proteomics Resource of Circulating Extracellular Vesicles for Biomarker Discovery in Pancreatic Cancer

    Bruno Bockorny, Lakshmi Muthuswamy ... Senthil K Muthuswamy
    Revised
    Reviewed Preprint v2 Updated
    1. Cancer Biology

    Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties

    Jae Hun Shin, Jooyoung Park ... Alfred LM Bothwell
    Revised
    Reviewed Preprint v2 Updated
    1. Cancer Biology

    Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing

    Einav Someach, Debdatta Halder ... Itay Tirosh
    Not yet revised
    Reviewed Preprint v1
    1. Cancer Biology

    Proteogenomic analysis of air-pollution-associated lung cancer reveals prevention and therapeutic opportunities

    Honglei Zhang, Chao Liu ... Gaofeng Li
    MAD1 and TPRN were identified as novel potential therapeutic targets of lung adenocarcinoma in female never-smokers from the Xuanwei area.
    1. Cancer Biology

    Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia model

    Tristan Gicquel, Fabio Marchiano ... Alice Carrier
    Pancreatic cancer-associated muscle atrophy is characterized by strong mitochondrial metabolic defects that are not limited to carbohydrate, protein, and redox metabolism, but also concern lipid and nucleic acid metabolisms.

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Tony Ng
    King's College London, United Kingdom
  3. Päivi Ojala
    University of Helsinki, Finland
  4. See more editors