Cancer Biology

Latest articles

1. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence

   Shou Liu et al.
2. 1. Cancer Biology
   2. Cell Biology

   A non-genetic, cell cycle dependent mechanism of platinum resistance in lung adenocarcinoma

   Alvaro Gonzalez Rajal et al.
3. 1. Cancer Biology

   Limited inhibition of multiple nodes in a driver network blocks metastasis

   Ali Ekrem Yesilkanal et al.
4. 1. Cancer Biology
   2. Cell Biology

   KSR1-and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

   Chaitra Rao et al.
5. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer

   Carter J Barger et al.

   FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.
6. 1. Cancer Biology

   Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus

   Asieh Naderi et al.

   Monogamous rodents of the genus Peromyscus, upon disruption of pair bonds, acquire increased oncogenic activity.
7. 1. Cancer Biology
   2. Developmental Biology

   An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

   Rediet Zewdu et al.

   Genetically engineered murine models reveal novel mechanisms of cell identity regulation in lung cancer and provide insights into the complex interplay between lineage specifiers and oncogenic signaling pathways in this disease.
8. 1. Cancer Biology

   Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells

   Takashi Ogino et al.

   The expression of the major circadian component CLOCK is a key regulator of stemness in breast cancer cells, which can be a novel strategy for breast cancer treatment.
9. 1. Cancer Biology
   2. Genetics and Genomics

   Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

   Sibylle Mitschka, Christine Mayr
10. 1. Cancer Biology
    2. Cell Biology

    Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression

    Linda Julian et al.

    In the absence of ROCK1 activation by caspases, apoptotic cells don’t undergo typical morphological changes, leading to sterile inflammation in the liver that increases tissue damage and suppresses tumor formation.