Cancer Biology

Cancer Biology

eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology

    The T Cell Receptor β Chain Repertoire of Tumor Infiltrating Lymphocytes Improves Neoantigen Prediction and Prioritization

    Thi Mong Quynh Pham, Thanh Nhan Nguyen ... Le Son Tran
    1. Medicine
    2. Cancer Biology

    Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes

    Patrick D Brandt, Dawayne Whittington ... Rebekah L Layton
    1. Cancer Biology

    Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway

    Elazar Besser, Anat Gelfand ... David Meiri
    The cannabinoids cannabidiol, cannabidivarin, and the newly identified 331-18A demonstrate antitumoral effects in Notch1-mutated leukemia, underscoring the potential and complexity of Cannabis as a novel treatment for cancer.
    1. Cancer Biology

    Targeting ribosome biogenesis as a novel therapeutic approach to overcome EMT-related chemoresistance in breast cancer

    Yi Ban, Yue Zou ... Dingcheng Gao
    Inhibiting the RiBi pathway impedes both EMT and MET processes, enhancing chemotherapy efficacy and presenting a novel avenue to tackle advanced breast cancer treatment resistance.
    1. Computational and Systems Biology
    2. Cancer Biology

    Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data

    Aurélie AG Gabriel, Julien Racle ... David Gfeller
    1. Cancer Biology

    TAK1-mediated phosphorylation of PLCE1 represses PIP2 hydrolysis to impede esophageal squamous cancer metastasis

    Qianqian Ju, Wenjing Sheng ... Cheng Sun
    1. Cell Biology
    2. Cancer Biology

    RUNX2 Isoform II Protects Cancer Cells from Ferroptosis by Promoting PRDX2 Expression in Oral Squamous Cell Carcinoma

    Junjun Huang, Rong Jia, Jihua Guo
    1. Cancer Biology

    Identification of novel myelodysplastic syndromes prognostic subgroups by integration of inflammation, cell-type composition, and immune signatures in the bone marrow

    Sila Gerlevik, Nogayhan Seymen ... Mohammad M Karimi
    Multi-omics factor analysis reveals transposable element expression as a risk factor and inflammation as a protective factor in myelodysplastic syndromes (MDS).
    1. Genetics and Genomics
    2. Cancer Biology

    NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in Solitary Fibrous Tumors

    Connor M Hill, Alexandra Indeglia ... Alessandro Gardini
    1. Cancer Biology
    2. Evolutionary Biology

    On the discovered Cancer Driving Nucleotides (CDNs) –Distributions across genes, cancer types and patients

    Lingjie Zhang, Tong Deng ... Chung-I Wu
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Highlights

    1. Cancer Biology

    Reproducibility in Cancer Biology

    Edited by Roger J Davis et al.
    1. Cancer Biology
    2. Computational and Systems Biology

    eLife publishes final papers from the Reproducibility Project: Cancer Biology

    Timothy M Errington, Maya Mathur ... Brian A Nosek
    1. Cancer Biology

    Toxicity: Fishing for protective compounds

    Giuliano Ciarimboli

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Wafik S El-Deiry
    Brown University, United States
  3. Eduardo Franco
    McGill University, Canada
  4. See more editors