Cancer Biology

Cancer Biology

eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology

    Multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer

    Wenjie Shi, Jianying Xu ... Ulf Dietrich Kahlert
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Conserved and Unique Features of Terminal Telomeric Sequences in ALT-Positive Cancer Cells

    Benura Azeroglu, Wei Wu ... Eros Lazzerini Denchi
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    • Compelling
    1. Computational and Systems Biology
    2. Cancer Biology

    Altered thymic niche synergistically drives the massive proliferation of malignant thymocytes

    Erika Tsingos, Advaita M Dick, Baubak Bajoghli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cancer Biology

    S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting the angiogenic function regulated by fatty acid metabolism

    Hong Huang, Ying Yang ... Le Zhang
    S100a4+ alveolar macrophages facilitate angiogenesis through CPT1A-PPAR-γ-mediated fatty acid metabolism, thereby triggering atypical adenomatous hyperplasia.
    1. Cancer Biology

    SETD2 suppresses tumorigenesis in a KRASG12C-driven lung cancer model and its catalytic activity is regulated by histone acetylation

    Ricardo J Mack, Natasha M Flores ... Or Gozani
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology

    Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment

    Youyou Zhang, Mu Xu ... Lin Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease
    2. Cancer Biology

    The lnc-FANCI-2 intrinsically restricts RAS signaling in HPV16-infected cervical cancer

    Haibin Liu, Lulu Yu ... Zhi-Ming Zheng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology

    Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing

    Einav Someach, Debdatta Halder ... Itay Tirosh
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Cancer cells differentially modulate mitochondrial respiration to alter redox state and enable biomass synthesis in nutrient-limited environments

    Sarah M Chang, Muhammad Bin Munim ... Matthew G Vander Heiden
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cancer Biology

    Erythrocytosis-inducing PHD2 mutations implicate biological role for N-terminal prolyl-hydroxylation in HIF1α oxygen-dependent degradation domain

    Cassandra C Taber, Wenguang He ... Michael Ohh
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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Highlights

    1. Cancer Biology

    Reproducibility in Cancer Biology

    Edited by Roger J Davis et al.
    1. Cancer Biology
    2. Computational and Systems Biology

    eLife publishes final papers from the Reproducibility Project: Cancer Biology

    Timothy M Errington, Maya Mathur ... Brian A Nosek
    1. Cancer Biology

    Toxicity: Fishing for protective compounds

    Giuliano Ciarimboli

Senior editors

  1. Eduardo Franco
    McGill University, Canada
  2. Tony Ng
    King's College London, United Kingdom
  3. Lynne-Marie Postovit
    University of Alberta, Canada
  4. See more editors