Skip to Content
eLife home page
Submit my research
(via ORCID - An ORCID is a persistent digital identifier for researchers)
Search the eLife site
Search by keyword or author
Limit my search to Cancer Biology
eLife publishes research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about
what we publish
and sign up for the
A versatile system to record cell-cell interactions
Rui Tang et al.
A novel reporter system that employs cell surface antigen-nanobody pairing enables physical interaction-dependent labeling and functional modification between diverse cell types.
Chromosomes and Gene Expression
A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells
Xiao Ling Li et al.
Discovery and initial characterization of a conserved small protein translated from a transcript annotated as a human long non-coding RNA.
eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis
Hang Ruan et al.
Genetic and transcriptomic analyses revealed that eIF4E S209 phosphorylation enables Myc and mutant
cooperation in colon cancer through stress- and glutamine-dependent growth and addiction.
Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma
Nataša Pavlović et al.
Inhibiting IRE1α decreases tumor cell proliferation and migration in hepatocellular carcinoma, therefore components of this ER-stress pathway may be therapeutically relevant for liver cancer.
Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
Keerthana Gnanapradeepan et al.
Enhanced metabolic efficiency associated with the tumor-predisposing African-centric p53 variant.
Immunology and Inflammation
The effects of age and systemic metabolism on anti-tumor T cell responses
Jefte M Drijvers et al.
A comprehensive literature review delineates the current knowledge of how systemic context, such as age and obesity, can impact CD8
T cell function, anti-tumor immunity, and immunotherapy responsiveness.
Protein phase separation and its role in tumorigenesis
Shan Jiang et al.
The current understanding of phase separation is summarized and its emerging roles in cancer are discussed in detail.
Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen
Hao Zhang et al.
reporter and genetic screens facilitated the functional interrogation of the
regulome and advanced our understanding of the molecular regulation network in
Genetics and Genomics
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway
Annie Wai Yeeng Chai et al.
Genome-wide CRISPR/Cas9 screens enable the identification of actionable vulnerabilities of oral squamous cell carcinoma, and their unique dependencies on YAP1 and WWTR1 of the Hippo pathway.
Immunology and Inflammation
Cytotoxic T-cells mediate exercise-induced reductions in tumor growth
Helene Rundqvist et al.
Exercise can induce metabolic changes that strikingly impact cytotoxic T cell function and in turn affect cancer progression.
Reproducibility in Cancer Biology
Edited by Roger J Davis et al.
Toxicity: Fishing for protective compounds
Biochemistry and Chemical Biology
Anti-Cancer Drugs: The mitochondrial paradox
Sophie L Penman et al.
University of California, Los Angeles, United States
McGill University, Canada
Fox Chase Cancer Center, United States
See more editors
Be the first to read new articles from eLife
Sign up for alerts
Please leave this field empty
Back to top