Cancer Biology

Cancer Biology

eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology

    Restraint of melanoma progression by cells in the local skin environment

    Yilun Ma, Mohita Tagore ... Richard M White
    1. Cancer Biology

    Super-enhancer-driven ZFP36L1 promotes PD-L1 expression in infiltrative gastric cancer

    Xujin Wei, Jie Liu ... Huiqin Zhuo
    CUT-Tag is used to identify super-enhancers (SEs) for the first time in gastric cancer, and the mRNA decay mechanism activated by SE-driven ZFP36L1 in infiltrative gastric cancer along with innovative experimental evidence demonstrating SPI1/ZFP36L1/HDAC3/PD-L1 signaling axis are presented.
    1. Cancer Biology
    2. Genetics and Genomics

    Gene Fusion: Decoding the identity of rare tumors

    Qingchen Yuan, Prabhjot Kaur, Olga A Guryanova
    Solitary fibrous tumors have gene expression signatures similar to those of neuroendocrine tumors.
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    1. Cancer Biology

    BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas

    Paul Huchede, Swann Meyer ... Marie Castets
    BMP2 and 7 synergize with H3.3K27M epigenetic context to establish a quiescent but invasive state in pediatric diffuse midline gliomas.
    1. Cancer Biology
    2. Immunology and Inflammation

    Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway

    Jianwen Chen, Bao Zhao ... Haitao Wen
    Deficiency or pharmacological inhibition of O-glcNac transferase (OGT) enhances tumor immunity in colorectal cancer models.
    1. Cancer Biology
    2. Evolutionary Biology

    High-density sampling reveals volume growth in human tumours

    Arman Angaji, Michel Owusu ... Johannes Berg

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Yamini Dalal
    National Cancer Institute, United States
  3. Wafik S El-Deiry
    Brown University, United States
  4. See more editors