Cancer Biology

Latest articles

1. 1. Cancer Biology

   Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer

   Bahman Afsari et al.
2. 1. Cancer Biology
   2. Cell Biology

   Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes

   Shima Ghoroghi et al.

   A combination of animal models reveal how the molecular mechanisms of exosome secretion (RalA/B-dependent) are linked to their cargo content and their function in breast cancer pre-metastatic niche formation.
3. 1. Biochemistry and Chemical Biology
   2. Cancer Biology

   Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells

   Lavanya H Palavalli Parsons et al.
4. 1. Cancer Biology
   2. Stem Cells and Regenerative Medicine

   Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium

   Madeline Sandoval et al.

   Skin epithelium can tolerate oncogene-expressing clones through a novel cellular mechanism of inter-clonal competition between renewing progenitors along the clone's edge and differentiating progenitors within the clone's core.
5. 1. Cancer Biology

   Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism

   Krystal Ann Orlando et al.

   BRG1 loss drives initiation and progression in human cancers through changes in specific differentiation programs in an AP-1-dependent manner.
6. 1. Cancer Biology
   2. Genetics and Genomics

   Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells

   Iris E Glykofridis et al.
7. 1. Cancer Biology
   2. Genetics and Genomics

   MITF reprograms the extracellular matrix and focal adhesion in melanoma

   Ramile Dilshat et al.
8. 1. Cancer Biology

   Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging

   Takahisa Maruno et al.

   Genetic lineage tracing approach combined with live imaging visualized the functional stem cell activity of Doublecortin-like kinase 1⁺ cells within pancreatic cancer in vivo.
9. 1. Cancer Biology

   Use of signals of positive and negative selection to distinguish cancer genes and passenger genes

   László Bányai et al.
10. 1. Cancer Biology

    Single-cell chromatin accessibility profiling of glioblastoma identifies an Invasive cancer stem cell population associated with lower survival

    Paul Guilhamon et al.