Cancer Biology

Cancer Biology

eLife publishes research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology
    2. Computational and Systems Biology

    Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways

    Pan Cheng, Xin Zhao ... Teresa Davoli
    RNA-level regulation of gene expression is negatively associated with protein-level regulation across cellular pathways in normal tissues and cancer.
    1. Cancer Biology
    2. Immunology and Inflammation

    Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy

    Amit Gutwillig, Nadine Santana-Magal ... Yaron Carmi
    Tumors escape killing by the immune system through generating transient spatial cell-in-cell structures that are impenetrable to cytotoxic compounds including lytic granules and chemotherapy.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

    Nuria Vilaplana-Lopera, Vincent Cuminetti ... Paloma Garcia
    Interplay between AML and stromal cells can initiate a mechanism involving gap junctions where ROS is transferred from cancer cells to stromal cells which then produce acetate which can in return be absorbed/utilised by the cancer cells.
    1. Cancer Biology
    2. Cell Biology

    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis

    Ricardo A Cordova, Jagannath Misra ... Kirk A Staschke
    1. Cancer Biology

    BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

    Judit Jimenez-Sainz, Joshua Mathew ... Ryan B Jensen
    1. Cancer Biology
    2. Cell Biology

    The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer

    Daniel Routledge, Sally Rogers ... Steffen Scholpp
    Signalling filopodia, also known as cytonemes, are a crucial transport mechanism of Wnt3 in gastric cancer and their emergence is controlled by Flot2.

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Wafik S El-Deiry
    Brown University, United States
  3. Caigang Liu
    Shengjing Hospital of China Medical University, China
  4. See more editors