Cancer Biology

Latest articles

1. 1. Cancer Biology
   2. Computational and Systems Biology

   Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways

   Pan Cheng, Xin Zhao ... Teresa Davoli

   RNA-level regulation of gene expression is negatively associated with protein-level regulation across cellular pathways in normal tissues and cancer.
2. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness

   Arnaud Carrier, Cécile Desjobert ... Paola B Arimondo
3. 1. Cancer Biology
   2. Immunology and Inflammation

   Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy

   Amit Gutwillig, Nadine Santana-Magal ... Yaron Carmi

   Tumors escape killing by the immune system through generating transient spatial cell-in-cell structures that are impenetrable to cytotoxic compounds including lytic granules and chemotherapy.
4. 1. Cancer Biology
   2. Medicine

   Photonic hyperthermia of malignant peripheral nerve sheath tumors at the third near-infrared biowindow

   Yihui Gu, Zhichao Wang ... Qingfeng Li
5. 1. Biochemistry and Chemical Biology
   2. Cancer Biology

   Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

   Nuria Vilaplana-Lopera, Vincent Cuminetti ... Paloma Garcia

   Interplay between AML and stromal cells can initiate a mechanism involving gap junctions where ROS is transferred from cancer cells to stromal cells which then produce acetate which can in return be absorbed/utilised by the cancer cells.
6. 1. Biochemistry and Chemical Biology
   2. Cancer Biology

   Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes

   Stefania Monterisi, Johanna Michl ... Pawel Swietach
7. 1. Cancer Biology
   2. Cell Biology

   GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis

   Ricardo A Cordova, Jagannath Misra ... Kirk A Staschke
8. 1. Cancer Biology

   BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

   Judit Jimenez-Sainz, Joshua Mathew ... Ryan B Jensen
9. 1. Cancer Biology

   Arbidol inhibits human esophageal squamous cell carcinoma growth in vitro and in vivo through suppressing ataxia telangiectasia and Rad3-related protein kinase

   Ning Yang, Xuebo Lu ... Kangdong Liu
10. 1. Cancer Biology
    2. Cell Biology

    The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer

    Daniel Routledge, Sally Rogers ... Steffen Scholpp

    Signalling filopodia, also known as cytonemes, are a crucial transport mechanism of Wnt3 in gastric cancer and their emergence is controlled by Flot2.