Cancer Biology

Cancer Biology

eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology
    2. Evolutionary Biology

    Punctuated mutagenesis promotes multi-step evolutionary adaptation in human cancers

    Christopher Graser, Wenbo Wu ... Franziska Michor
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cancer Biology

    Low-dose chemotherapy combined with delayed immunotherapy in the neoadjuvant treatment of non-small cell lung cancer and dynamic monitoring of the drug response in peripheral blood

    Chaoyang Liang, Qi Song ... Bo Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Cancer Biology

    Mitochondrial stress-induced protein carboxyl-terminal alanine threonine tailing (msiCAT-tailing) facilitates glioblastoma tumorigenesis through the modulation of mitochondrial functions

    Bei Zhang, Ting Cai ... Zhihao Wu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cancer Biology

    Transcription Factor-Dependent Cancers: Targeting chromatin remodeling complexes to treat uveal melanoma

    Jonas A Nilsson
    A novel compound that inhibits the BAF chromatin remodeling complex causes regression in an animal model of the incurable cancer uveal melanoma.
    Version of Record
    Insight
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Telomeres control human telomerase (TERT) expression through non-telomeric TRF2

    Antara Sengupta, Soujanya Vinayagamurthy ... Shantanu Chowdhury
    Telomere length controls hTERT expression by modulating TRF2 distribution and PRC2-mediated repression, highlighting a self-regulatory mechanism in cancer.
    1. Microbiology and Infectious Disease
    2. Cancer Biology

    RadD from Fusobacterium nucleatum Engages NKp46 to Promote Antitumor Cytotoxicity

    Ahmed Rishiq, Johanna Galski ... Ofer Mandelboim
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism

    Priyojit Das, Rebeca San Martin ... Rachel Patton McCord
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cancer Biology
    2. Physics of Living Systems

    Robust assessment of asymmetric division in colon cancer cells

    Domenico Caudo, Chiara Giannattasio ... Mattia Miotto
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Synthetic gene circuits that selectively target RAS-driven cancers

    Gabriel Senn, Leon Nissen, Yaakov Benenson
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers

    Richard C Centore, Luis MM Soares ... Steven F Bellon
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
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Highlights

    1. Cancer Biology

    Chromatin remodeling and cancer

    Jonas A Nilsson
    1. Cancer Biology

    Reproducibility in Cancer Biology

    Edited by Roger J Davis et al.
    1. Cancer Biology
    2. Computational and Systems Biology

    eLife publishes final papers from the Reproducibility Project: Cancer Biology

    Timothy M Errington, Maya Mathur ... Brian A Nosek

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Eduardo Franco
    McGill University, Canada
  3. Tony Ng
    King's College London, United Kingdom
  4. See more editors