Cancer Biology

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Cancer Biology

   FOXP2 confers oncogenic effects in prostate cancer

   Xiaoquan Zhu, Chao Chen ... Yanyang Zhao

   FOXP2, encoding a forkhead-box transcription factor regarded as vital to proper development of human speech, was revealed to have an oncogenic potential and activate MET signaling in prostate cancer.
2. 1. Cancer Biology
   2. Genetics and Genomics

   Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells

   Ann-Kathrin Herzfeldt, Marta Puig Gamez ... Lee Kim Swee
3. 1. Cancer Biology
   2. Genetics and Genomics

   Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

   Van Thien Chi Nguyen, Trong Hieu Nguyen ... Le Son Tran
4. 1. Cancer Biology
   2. Cell Biology

   Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics

   Timothy J. Walker, Eduardo Reyes-Alvarez ... Lois M. Mulligan
5. 1. Cancer Biology

   Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1

   Huan Fang, Wenlong Ren ... Ceshi Chen
6. 1. Cancer Biology

   ScRNA-seq of Diverse Pheochromocytoma Patients Reveals Distinct Microenvironment Characteristics and Supports an Informative Molecular Classification System

   Sen Qin, Yawei Xu ... Zheng Zhang
7. 1. Cancer Biology
   2. Cell Biology

   EPAC1 inhibition protects the heart from doxorubicin-induced toxicity

   Marianne Mazevet, Anissa Belhadef ... Eric Morel

   The inhibition of EPAC1, a cAMP-binding protein, appears as a potential therapeutic strategy to limit doxorubicin-induced cardiotoxicity without interfering with its antitumoral activity.
8. 1. Epidemiology and Global Health
   2. Medicine
   3. Cancer Biology

   

   Special Issue: The impact of the COVID-19 pandemic on cancer prevention, control, care and survivorship

   Edited by Eduardo Franco et al.

   Our latest Special Issue brings together research covering many different aspects of the impact of the COVID-19 pandemic on cancer outcomes across the globe.
9. 1. Cancer Biology
   2. Cell Biology

   Cancer Survivorship: Protecting the heart

   Joshua M Inglis, Arduino A Mangoni

   Blocking a protein known as EPAC1 may prevent the development of heart-related side effects caused by a chemotherapy drug.
10. 1. Cancer Biology
    2. Computational and Systems Biology

    Spatial transformation of multi-omics data unlocks novel insights into cancer biology

    Mateo Sokač, Asbjørn Kjær ... Nicolai J Birkbak

    GENIUS provides a deep learning framework for multi-omics integration that transforms data into spatial images, using integrated gradients to reveal novel and critical cancer gene association.