Cancer Biology

Cancer Biology

eLife publishes research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology
    2. Cell Biology

    Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation

    Maxim I Maron et al.
    Biochemical, transcriptomic, and proteomic analyses reveal that protein arginine methyltransferases post-transcriptionally regulate intron detention—introns that persist in nuclear polyadenylated RNA—through methylation of RNA splicing and processing factors.
    1. Cancer Biology
    2. Ecology

    Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe

    Daniel Garcia-Souto et al.
    Genome sequencing analysis dissects the origins and evolution of cancer transmission between clam species in the Seas of Southern Europe.
    1. Cancer Biology
    2. Genetics and Genomics

    Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma

    Oscar Urtatiz et al.
    G alpha q/11 signaling can either promote or inhibit melanocyte growth through a reversible switch that is controlled by the microenvironment and that shapes the mutational diversity of melanoma subtypes.
    1. Cancer Biology
    2. Computational and Systems Biology

    Quantitative analysis of tumour spheroid structure

    Alexander P Browning et al.
    A novel quantitative framework to analyse the inner structure of tumour spheroids in terms of the mechanisms that underly growth.
    1. Cancer Biology

    Hyaluronic acid fuels pancreatic cancer cell growth

    Peter K Kim et al.
    Pancreatic cancers can utilize hyaluronic acid, an abundant extracellular matrix component in the tumor microenvironment, to fuel cancer cell metabolism and growth.
    1. Cancer Biology
    2. Cell Biology

    Single-cell transcriptome analysis identifies a unique tumor cell type producing multiple hormones in ectopic ACTH and CRH secreting pheochromocytoma

    Xuebin Zhang et al.
    A novel multi-hormones secreting chromaffin-like cell type was identified using single-cell RNA sequencing, suggesting the molecular mechanism of ectopic ACTH and CRH pheochromocytoma associated with Cushing’s syndrome.
    1. Cancer Biology
    2. Cell Biology

    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

    Natalia Vydra et al.
    Heat shock factor 1 is involved in estrogen-induced chromatin remodeling in estrogen receptor-positive breast cancer cells.

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Eduardo Franco
    McGill University, Canada
  3. Päivi Ojala
    University of Helsinki, Finland
  4. See more editors