About
Editors and people

Editors for Chromosomes and Gene Expression

We aim to review research, performed using genetic, biochemical and structural approaches, that relates to all aspects of the central dogma of biology, specifically DNA replication, repair and recombination, transcription and RNA processing, and translation. We welcome studies in organisms from bacteria to humans that provide new insights into the mechanisms of these processes – including how they are regulated, for example during cell differentiation – and the defects in these processes that contribute to disease. Read the latest research in this subject area.

Type

Senior editors

Yamini Dalal

National Cancer Institute, United States

Yamini Dalal did her graduate work on chromatin structure with Arnie Stein and Minou Bina at Purdue University (PhD, 2003), and her postdoctoral research on centromeres with Steve Henikoff at the Fred Hutch Cancer Research Center (2007). She is currently a Senior Investigator leading the Chromosome Structure and Epigenetics Mechanism Unit within the Laboratory of Receptor Biology and Gene Expression at the Center for Cancer Research of the NCI/NIH in Bethesda. Her lab focuses on histones, which package the entirety of the human genome into chromatin. Using a combination of chromatin biochemistry, computational modelling, atomic force microscopy (AFM), genetics, genomics and cell biology, Dr. Dalal and colleagues are investigating whether chromatin adopts alternate structural conformations in cancer cells, the functional consequences of large-scale chromosomal alterations upon the cancer epigenome, and identifying small molecules which can target these structures or processes.

Expertise
Cancer Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromatin
centromeres
chromosomes
mitosis
chromosome cancer biology
histone variants
nucleosomes
histones

Experimental organism
human
mouse

Competing interests statement
Dr. Dalal is serving as Deputy Editor of eLife in her personal capacity as a chromosome biology expert with a deep interest in molecular and cellular biology, not as a representative of the NIH.
Silke Hauf

Virginia Tech, United States

Silke Hauf is Associate Professor in the Department of Biological Sciences at Virginia Tech. She received her MD from the University of Wuerzburg, Germany, and did postdoctoral training at the Institute of Molecular Pathology (IMP) in Vienna, Austria, and the University of Tokyo, Japan. She joined Virginia Tech in 2014 after being a group leader at the Friedrich Miescher Laboratory of the Max Planck Society in Tuebingen, Germany. Her work explores how cells execute the cell cycle reliably and ensure the proper inheritance of chromosomes. To obtain a systems understanding of these processes, her group often collaborates with theoretical biologists. At Virginia Tech, she also serves as Associate Director of the Center for the Mathematics of Biosystems.

Expertise
Cell Biology
Chromosomes and Gene Expression

Research focus
cell cycle regulation
mitotic checkpoint
chromosome segregation
quantitative imaging
gene expression noise
post-transcriptional regulation

Experimental organism
S. pombe

Competing interests statement
Silke Hauf receives funding from the National Institutes of Health, and is on the Advisory Editorial Board of Life Science Alliance.
Adèle L Marston

University of Edinburgh, United Kingdom

Adèle Marston is Professor of Cell Biology at the University of Edinburgh, a Wellcome Investigator and Director of the Wellcome Discovery Research Platform for Hidden Cell Biology. Adèle investigates the fundamental mechanisms by which cells reproduce themselves and transmit their genome to the next generation. She has a particular interest in meiosis, the cell division that generates eggs and sperm. Her laboratory takes a multi-disciplinary approach to identify the fundamental mechanisms of chromosome segregation in model organisms, including yeast, frogs and mice. To understand the relevance of these discoveries for human fertility, she also works with clinicians to investigate the origins of chromosome segregation errors in human oocytes.

Expertise
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromosome biology
cell biology
reproductive biology
meiosis
mitosis
chromosome segregation
cell cycle

Experimental organism
S. cerevisiae
S. pombe
xenopus laevis
mouse
human

Competing interests statement
Adèle Marston is funded by Wellcome. She has served as Reviewing Editor for eLife.
Lori Sussel

University of Colorado Anschutz Medical Campus, United States

Lori Sussel is a Professor of Pediatrics and Cell & Developmental Biology at the University of Colorado Anschutz Medical Center. She also serves as Director of the Research Division at Barbara Davis Center for Diabetes. She received her BA in Microbiology at the University of Texas, Austin and her PhD in Molecular Biology from Columbia University where she investigated transcriptional regulation in yeast. She pursued postdoctoral studies first with Dr. Barbara Meyer (UC Berkeley) and then Dr. John Rubenstein (UC San Francisco) where applied her interests in transcriptional regulation of cell fates to developmental processes. During her postdoctoral studies, she was funded by a Life Science Research Fellowship, a NIH F32 fellowship and the A.P Giannini Foundation. She began her independent career at the University of Colorado where she initiated her studies on the transcriptional regulation of pancreatic islet cell fates. In 2006, she moved to the Naomi Berrie Diabetes Center at Columbia University where she continued to investigate pancreas development and islet biology, expanding her interests in transcriptional regulation to roles of long non-coding RNAs and RNA processing. In 2016, she returned to the University of Colorado to become the Director of Basic and Translational Research at the Barbara Davis Center for Diabetes. Her research continues to focus on pancreas development and islet biology using mice and human stem cell platforms to understand the molecular underpinnings of the islet dysfunctions associated with diabetes. In this position, she holds the Sissel and Findlow Family Chair in Stem Cell Biology.

Expertise
Chromosomes and Gene Expression
Developmental Biology
Stem Cells and Regenerative Medicine

Research focus
pancreas development
islet biology
transcriptional regulation
long non-coding RNAs
diabetes
developmental genetics

Experimental organism
mouse
human cells

Competing interests statement
Lori Sussel has received funding from the National Institutes of Health, the American Diabetes Association, and the Juvenile Diabetes Research Foundation. In addition to being a Senior Editor for eLife, she currently serves as an Associate Editor for Science Advances, and is on the editorial board of Developmental Biology and Life Science Alliance. She previously served as an Associate Editor for Diabetes and Pediatric Diabetes and was on the editorial board of Molecular Metabolism.

Reviewing editors

Andres Aguilera

CABIMER, University of Seville, Spain

Expertise
Chromosomes and Gene Expression

Research focus
genome instability
DSB repair
replication
transcription
R loops
recombination
chromatin

Experimental organism
S. cerevisiae
human cells
Bhat Altaf

University of Kashmir, India

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromatin
heterochromatin
transcription
histone modifications
genome organisation
RNA-binding proteins
chromatin in DNA repair
epigenetics
autophagy

Experimental organism
human
budding yeast
fission yeast
Nicolas Altemose

Stanford University, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Computational and Systems Biology

Research focus
chromatin
centromeres
heterochromatin
epigenomics
microfluidics
meiotic recombination
Long-read sequencing
Repetitive DNA

Experimental organism
human
mouse
Lysangela Alves

Instituto Carlos Chagas, Brazil

Expertise
Chromosomes and Gene Expression
Microbiology and Infectious Disease

Research focus
RNA biology
molecular mycology
extracellular vesicles
host-pathogen interaction
molecular parasitology
gene expression regulation
candida
Richard Amasino

University of Wisconsin-Madison, United States

Expertise
Plant Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
plant development and epigenetics

Experimental organism
A. thaliana
B. distachyon
Aseem Z Ansari

St. Jude Children's Research Hospital, United States

Expertise
Chromosomes and Gene Expression
Biochemistry and Chemical Biology
Genetics and Genomics

Research focus
gene expression
chemical biology
synthetic biology
transcription factors
molecular recognition
synthetic gene regulators
transcription therapy
RNA polymerase II regulation
transcriptional kinases
DNA binding specificity
H. Efsun Arda

National Cancer Institute, United States

Expertise
Developmental Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
pancreas
single-cell
enhancers
chromatin
Pedro Batista

National Institutes of Health, National Cancer Institute, United States

Expertise
Cancer Biology
Chromosomes and Gene Expression

Research focus
RNA modifications
tRNA
RNA demethylases
m6A
mRNA processing
Bérénice A Benayoun

University of Southern California, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Immunology and Inflammation

Research focus
aging
macrophages
inflammation
sex differences
menopause
sex hormones

Experimental organism
mouse
African turquoise killifish
Michael R Botchan

University of California, Berkeley, United States

Expertise
Biochemistry and Chemical Biology
Chromosomes and Gene Expression

Research focus
DNA replication
DNA repair

Experimental organism
D. melanogaster
Sigurd J Braun

Justus-Liebig University Giessen, Germany

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromatin
epigenetics
gene silencing
genome stability
ubiquitin
histone modifications
phenotypic screens

Experimental organism
fission yeast
budding yeast
Joshua Brickman

Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), Denmark

Expertise
Chromosomes and Gene Expression
Developmental Biology
Stem Cells and Regenerative Medicine

Research focus
embryonic stem cells
endoderm
pluripotency
lineage priming
transcription factors

Experimental organism
mouse
Xenopus
Gertraud Burger

University of Montreal, Canada

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Microbiology and Infectious Disease
Plant Biology

Research focus
genomics
transcriptomics
proteomics
bioinformatics
microeukaryotes
microbe-plant interactions
eukaryotic evolution
Paula Casati

Center of Photosynthetic And Biochemical Studies (CEFOBI), Argentina

Expertise
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Plant Biology

Research focus
genome stability
abiotic stress in plants
chromatin remodelling
cell cycle regulation
flavonoid metabolism
Xin Chen

Johns Hopkins University, United States

Expertise
Developmental Biology
Chromosomes and Gene Expression

Research focus
germ cells
stem cells
asymmetric cell division
histones
epigenetics
transcription

Experimental organism
C. elegans
D. melanogaster
Irene E Chiolo

University of Southern California, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
DNA repair
double strand break repair
DNA recombination
chromosome dynamics
nuclear architecture
nuclear dynamics
nuclear actin filaments

Experimental organism
D. melanogaster
mouse
Julia P Cooper

University of Colorado Anschutz Medical Campus, United States

Expertise
Chromosomes and Gene Expression
Cell Biology
Genetics and Genomics

Research focus
telomeres
centromeres
genome stability
Jose Renato Rosa Cussiol

Federal University of São Paulo, Brazil

Expertise
Biochemistry and Chemical Biology
Cell Biology
Cancer Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
DNA damage response
yeast genetics
DNA damage signaling
genomic instability
inositol metabolism
inositol polyphosphate pathway
Weiwei Dang

Baylor College of Medicine, United States

Expertise
Cell Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
aging
epigenetics
histone modifications
chromatin
chromatin remodeling
yeast
yeast aging
stem cell aging

Experimental organism
S. cerevisiae
C. elegans
mouse
human
Jeremy Day

University of Alabama at Birmingham, United States

Expertise
Neuroscience
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
CRISPR/Cas
gene regulation
genomic enhancers
long non-coding RNAs
drug addiction
dopamine
reward
motivated behavior

Experimental organism
rat
mouse
cell cultures
Natalia De Miguel

Instituto Tecnológico de Chascomús, Argentina

Expertise
Cell Biology
Chromosomes and Gene Expression
Microbiology and Infectious Disease

Research focus
parasite
extracellular vesicles
host-parasite interactions
epigenetics
chromatin
Paul Donlin-Asp

University of Edinburgh, United Kingdom

Expertise
Cell Biology
Neuroscience
Chromosomes and Gene Expression

Research focus
mRNA localization
protein synthesis
synapses
post-transcriptional gene regulation
RNA binding proteins
neurodevelopmental disorders
mRNA
Eugene P Duff

Imperial College London, United States

Expertise
Genetics and Genomics
Neuroscience
Chromosomes and Gene Expression

Research focus
proteomics
dementia
functional neuroimaging
functional connectivity
single cell RNA sequencing
gene expression networks
multimorbidity
Kevin Eade

Lowy Medical Research Institute, United States

Expertise
Cell Biology
Stem Cells and Regenerative Medicine
Chromosomes and Gene Expression

Research focus
developmental biology
developmental neurobiology
organoids
retina
metabolism
directed differentiation
disease modeling
Sandeep M Eswarappa

Indian Institute of Science Bangalore, India

Expertise
Chromosomes and Gene Expression
Cell Biology

Research focus
mRNA
translation
translational recoding
genetic diseases
erythrocytes
RNA-based therapeutics
Yvonne Fondufe-Mittendorf

Van Andel Institute, United States

Expertise
Genetics and Genomics
Chromosomes and Gene Expression
Cancer Biology

Research focus
gene expression
chromatin biology
toxicology
RNA biology
nucleosome structure
Arun K Ganesan

University of New Mexico, United States

Expertise
Cancer Biology
Chromosomes and Gene Expression

Research focus
epigenetic regulation
chromatin biology
RNA-chromatin interactions
LncRNA
Ziyue Gao

University of Pennsylvania, United States

Expertise
Evolutionary Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
population genetics
human genetics
mutation rate
natural selection
genetic variation
ancient DNA

Experimental organism
human
non-human primates
Thomas Gingeras

Cold Spring Harbor Laboratory, United States

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
genomics
gene expression
regulatory networks
chromosomal modification

Experimental organism
D. melanogaster
human
mouse
Simona Giunta

Sapienza University of Rome, Italy

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
centromeres
Repetitive DNA
chromatin
DNA damage
DNA damage response
mutagenesis
epigenomics
DNA damage repair
Gustavo H Goldman

Universidade de Sao Paulo, Brazil

Expertise
Biochemistry and Chemical Biology
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
filamentous fungi
Aspergillus
secondary metabolites
gene expression
molecular biology
infectious diseases
drug tolerance
Alla Grishok

Boston University, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
small RNAs
epigenetics
DOT1L
H3K79
argonaute

Experimental organism
C. elegans
Li Guohong

Chinese Academy of Sciences, National Laboratory of Biomacromolecules, Institute of Biophysics, China

Expertise
Chromosomes and Gene Expression

Research focus
epigenetics
chromatin
transcription
histone variants
centromere
histone modifications
Aditi U Gurkar

University of Pittsburgh, United States

Expertise
Medicine
Chromosomes and Gene Expression
Cell Biology

Research focus
aging
cellular senescence
DNA damage and repair
metabolism
cardiac disease and aging
Wolf-Dietrich Heyer

University of California, Davis, United States

Expertise
Chromosomes and Gene Expression

Research focus
DNA repair
genome instability
homologous recombination
genome rearrangements
protein:DNA interactions

Experimental organism
S. cerevisiae
S. pombe
human cells
Alan G Hinnebusch

Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

Expertise
Chromosomes and Gene Expression

Research focus
protein synthesis
translational control

Experimental organism
S. cerevisiae
Ahmad S Khalil

Boston University, United States

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology

Research focus
synthetic biology
systems biology
gene regulation
epigenetics
molecular evolution
technology development
Sangjin Kim

University of Illinois at Urbana-Champaign, United States

Expertise
Chromosomes and Gene Expression
Physics of Living Systems
Structural Biology and Molecular Biophysics
Cell Biology

Research focus
RNA biology
transcription
translation
diffusion
chromosome dynamics
single molecule imaging and tracking

Experimental organism
E. coli
Megan C King

Yale School of Medicine, United States

Expertise
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Physics of Living Systems

Research focus
nuclear envelope
nuclear lamins
LINC complex
nuclear mechanics
DNA repair
genome organisation

Experimental organism
mouse
Tapas K Kundu

Jawaharlal Nehru Centre for Advanced Scientific Research, India

Expertise
Cancer Biology
Chromosomes and Gene Expression
Biochemistry and Chemical Biology

Research focus
epigenetics
chromatin organization
nonhistone chromatin proteins
epigenetic regulation of diseases
eukaryotic transcription regulation
small molecule modulators of epigenetic enzymes

Experimental organism
human
mouse
Ashish Lal

National Institutes of Health, United States

Expertise
Cancer Biology
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
RNA biology
lncRNAs
microRNAs
gene regulation
cancer biology
p53

Experimental organism
human
Dan Larhammar

Uppsala University, Sweden

Expertise
Medicine
Evolutionary Biology
Neuroscience
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
evolution
gene/genome duplications
cellular and molecular neuroscience
G protein-coupled receptors (GPCR)
neuropeptides
endocrine peptides
phototransduction
ligand-gated ion channels

Experimental organism
human
zebrafish
Luis F Larrondo

Pontificia Universidad Católica de Chile, Chile

Expertise
Microbiology and Infectious Disease
Chromosomes and Gene Expression

Research focus
circadian biology
photobiology
synthetic biology
gene expression
fungal biology
plant pathogenic fungi
filamentous fungi

Experimental organism
S. cerevisiae
N. crassa
Jeannie T Lee

Massachusetts General Hospital, United States

Expertise
Chromosomes and Gene Expression

Research focus
non-coding RNA
X-chromosome inactivation
imprinting
epigenetics
chromatin
Sylvia Lee

Cornell University, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
aging

Experimental organism
C. elegans
Scott F Leiser

University of Michigan, United States

Expertise
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Neuroscience

Research focus
aging
longevity
hypoxia
geroscience
proteostasis
stress response
flavin-containing monooxygenase
healthspan
Falong Lu

Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China

Expertise
Developmental Biology
Genetics and Genomics
Stem Cells and Regenerative Medicine
Chromosomes and Gene Expression

Research focus
epigenetics
RNA modifications
imprinting
stem cells
reprogramming
poly(A) tail
early embryo
chromatin modifications

Experimental organism
mouse
human
Vincent J Lynch

University at Buffalo, State University of New York, United States

Expertise
Chromosomes and Gene Expression
Evolutionary Biology
Genetics and Genomics

Research focus
evolutionary medicine
evolutionary cell biology
cancer
gene regulation
developmental evolution (DevoEvo)
pregnancy
Binyam Mogessie

Yale University, United States

Expertise
Cell Biology
Developmental Biology
Chromosomes and Gene Expression

Research focus
meiosis
mitosis
oocytes
actin
microtubules
chromosome segregation
chromosome cohesion
chromosome organisation
kinetochores
aneuploidy
fertility

Experimental organism
mouse
human
pig
Salem Y Mohamed

Zagazig University, Egypt

Expertise
Cancer Biology
Cell Biology
Chromosomes and Gene Expression
Epidemiology and Global Health
Genetics and Genomics
Immunology and Inflammation
Medicine
Microbiology and Infectious Disease

Research focus
advanced endoscopy
cell biology
cancer
inflammation
genetics
basic medicine
Marcelo A Mori

State University of Campinas, Brazil

Expertise
Biochemistry and Chemical Biology
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Immunology and Inflammation

Research focus
aging
metabolism
obesity
adipose tissue
microRNAs
endocrinology
integrative physiology
Marisa Nicolás

Laboratório Nacional de Computação Científica, Brazil

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
molecular biology
bioinformatics
genomics
transcriptomics
multi-omics approaches
clinical pathogens
antimicrobial resistance
metabolic regulatory networks
transcriptional regulatory networks
Dimple Notani

National Centre for Biological Sciences, India

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
genomics
single cell perturbations
molecular biology
microscopy
Izuchukwu Okafor

Nnamdi Azikiwe University, Nigeria

Expertise
Cancer Biology
Cell Biology
Chromosomes and Gene Expression
Developmental Biology
Epidemiology and Global Health
Genetics and Genomics
Medicine
Neuroscience

Research focus
developmental biology
reproductive biology
gene expression
molecular biology
public health
reproductive health
medical education
anatomical sciences
neuroreproduction
Anna Panchenko

Queen's University, Canada

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Cancer Biology

Research focus
molecular modeling
bioinformatics
machine learning
molecular dynamics simulations
cancer mutations
chromosome and nucleosome dynamics
Stephen Parker

University of Michigan, United States

Expertise
Genetics and Genomics
Chromosomes and Gene Expression
Computational and Systems Biology

Research focus
diabetes
disease susceptibility
functional genomics
comparative genomics
population genomics

Experimental organism
human
mouse
rat
David A Paz-Garcia

Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Mexico

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Ecology
Evolutionary Biology
Genetics and Genomics
Microbiology and Infectious Disease
Plant Biology

Research focus
marine life
coral reefs
phylogenomics
population genomics
morphometrics
gene expression
statistics
coding
Jun Wei Pek

Temasek Life Sciences Laboratory, Singapore

Expertise
Cell Biology
Chromosomes and Gene Expression
Developmental Biology
Stem Cells and Regenerative Medicine

Research focus
germline
reproductive biology
noncoding RNA
RNA biology
epigenetic inheritance

Experimental organism
drosophila
human
Gang Peng

Indiana University, United States

Expertise
Medicine
Computational and Systems Biology
Chromosomes and Gene Expression

Research focus
bioinformatics
epigenetics
sequencing
DNA methylation
Newborn Screening
Michael Perry

University of California, San Diego, United States

Expertise
Developmental Biology
Chromosomes and Gene Expression

Research focus
evo-devo
developmental neurobiology
stochasticity in development
sexual dimorphism
cell fate specification
sensory system evolution

Experimental organism
D. melanogaster
butterflies
insects
mosquitos
house flies
Benjamin L Prosser

University of Pennsylvania Perelman School of Medicine, United States

Expertise
Cell Biology
Physics of Living Systems
Chromosomes and Gene Expression

Research focus
cardiac function
muscle
cardiomyocytes
mechanotransduction
cytoskeleton
microtubules
sarcomere
Tania Reis

University of Colorado Anschutz Medical Campus, United States

Expertise
Genetics and Genomics
Chromosomes and Gene Expression
Neuroscience

Research focus
obesity
energy homeostasis
RNA binding proteins
sex differences
alternative splicing

Experimental organism
D. melanogaster
Olivia S Rissland

University of Colorado School of Medicine, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Developmental Biology

Research focus
post-transcriptional regulation
RNA
translation
maternal-to-zygotic transition
small RNAs
RNA decay

Experimental organism
drosophila
Sergio Ruiz Macias

National Cancer Institute, NIH, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Stem Cells and Regenerative Medicine

Research focus
embryonic stem cells
pluripotency
totipotency
chromatin
transcription factors

Experimental organism
mouse
Reut Shalgi

Technion - Israel Institute of Technology, Israel

Expertise
Cell Biology
Genetics and Genomics
Computational and Systems Biology
Chromosomes and Gene Expression

Research focus
stress response
ER stress
UPR
heat shock response
chaperones
protein aggregation
Xiaohua Shen

Tsinghua University, China

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
non-coding RNA
RNA binding proteins
Xiaobing Shi

Van Andel Institute, United States

Expertise
Chromosomes and Gene Expression

Research focus
chromatin
nucleosome
transcription
histone modifications
acetylation

Experimental organism
mouse
human
Akira Shinohara

Osaka University, Japan

Expertise
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Cell Biology

Research focus
recombination
DSB repair
meiosis
chromosome
DNA damage response

Experimental organism
S. cerevisiae
human
mouse
Judith Simcox

University of Wisconsin-Madison, United States

Expertise
Biochemistry and Chemical Biology
Cell Biology
Chromosomes and Gene Expression

Research focus
lipidomics
metabolic disease
molecular biology
lipid metabolism
fatty acids
Yan Song

Peking University, China

Expertise
Neuroscience
Developmental Biology
Stem Cells and Regenerative Medicine
Chromosomes and Gene Expression

Research focus
developmental neurobiology
cell fate decisions
epigenetics
stem cells
neurodevelopmental disorders
transcriptional control
cell fate memory

Experimental organism
mouse
D. melanogaster
Timothy J Stasevich

Colorado State University, United States

Expertise
Chromosomes and Gene Expression
Cell Biology
Physics of Living Systems

Research focus
gene expression
transcription
translation
RNA biology
chromatin dynamics
genome organization
fluorescence microscopy
single molecule imaging
intrabodies
Viji Subramanian

Indian Institute of Science Education and Research Tirupati, India

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromosome segregation
meiosis
DNA repair and recombination
chromosome structure and dynamics
genome integrity
crossover
N. Ravi Sundaresan

Indian Institute of Science, India

Expertise
Cell Biology
Medicine
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Stem Cells and Regenerative Medicine

Research focus
reversable acetylation
ADP-ribosylation
cellular senescence and aging
sirtuins
cardiac and skeletal muscle diseases
fibrosis

Experimental organism
human
mouse
rat
Summer Thyme

University of Massachusetts Medical School, United States

Expertise
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Developmental Biology
Genetics and Genomics
Neuroscience

Research focus
neurodevelopment
neurogenetics
CRISPR/Cas9
RNA
single cell RNA sequencing
behavior

Experimental organism
zebrafish
Kenichi Tsuda

Huazhong Agricultural University, China

Expertise
Plant Biology
Chromosomes and Gene Expression
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
plant immunity
phytohormones
pathogen
microbiome
transcriptome

Experimental organism
maize
Arabidopsis
Pseudomonas
xanthomonas
Elçin Ünal

University of California, Berkeley, United States

Expertise
Chromosomes and Gene Expression

Research focus
gametogenesis
aging
age-induced cellular damage
meiotic chromosome segregation

Experimental organism
S. cerevisiae
C. elegans
Ashley Webb

Buck Institute for Research on Aging, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Neuroscience
Stem Cells and Regenerative Medicine

Research focus
aging
epigenetics
gene regulation
stem cells
hypothalamus

Experimental organism
mouse
Blake Wiedenheft

Montana State University, United States

Expertise
Chromosomes and Gene Expression
Microbiology and Infectious Disease

Research focus
bacteriophages
genome editing
host-parasite interactions
Alyssa M Wilson

Icahn School of Medicine at Mount Sinai, United Kingdom

Expertise
Neuroscience
Cell Biology
Genetics and Genomics
Chromosomes and Gene Expression
Computational and Systems Biology

Research focus
single cell biology
multi-omics
neuroinformatics
cellular neuroanatomy
disease-related neurodegeneration
bioinformatics methods development

Experimental organism
human
mouse
Jerry L Workman

Stowers Institute for Medical Research, United States

Expertise
Chromosomes and Gene Expression

Research focus
chromatin
transcription
nucleosome
histone
Jie Xiao

Johns Hopkins University, United States

Expertise
Biochemistry and Chemical Biology
Cell Biology
Chromosomes and Gene Expression
Microbiology and Infectious Disease
Physics of Living Systems
Structural Biology and Molecular Biophysics

Research focus
single molecule biophysics
microbiology
cell division
cell wall
gene expression

Experimental organism
E. coli
Jian Xu

St. Jude Children's Research Hospital, United States

Expertise
Cancer Biology
Chromosomes and Gene Expression
Developmental Biology
Genetics and Genomics
Stem Cells and Regenerative Medicine

Research focus
hematopoiesis
erythropoiesis
myeloid leukemia
epigenetics
transcription regulation
enhancer
metabolism

Experimental organism
human
mouse
Yukiko M Yamashita

HHMI, University of Michigan, United States

Expertise
Cell Biology
Developmental Biology
Chromosomes and Gene Expression
Stem Cells and Regenerative Medicine

Research focus
stem cell niche
asymmetric cell division
satellite DNA
germline immortality
ribosomal DNA

Experimental organism
D. melanogaster
Zhiguo Zhang

Columbia University Medical Center, United States

Expertise
Chromosomes and Gene Expression
Cancer Biology

Research focus
epigenetic inheritance
chromatin
DNA replication
brain tumors
histone chaperones
histone modifications
oncohistone mutations
epigenomes
Yu Zhao

Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, China

Expertise
Biochemistry and Chemical Biology
Cancer Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
prostate cancer
noncoding RNA
m6A
epigenetics
enhancer
DNA damage
senescence
radiotherapy
Han Zhu

University of Colorado Anschutz Medical Campus, United States

Expertise
Cell Biology
Chromosomes and Gene Expression
Developmental Biology
Genetics and Genomics
Stem Cells and Regenerative Medicine

Research focus
pluripotent stem cells
human embryonic cells
human organoid
stem cell derived pancreatic islets
pancreatic islet development
pancreatic islet function
diabetes
gene regulation
single-cell genomics
Daniel Zilberman

John Innes Centre, United Kingdom

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Plant Biology

Research focus
DNA methylation
chromatin
epigenetics
epigenomics
evolution

Experimental organism
rice
A. thaliana