Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression

    Transcription factor condensates, 3D clustering, and gene expression enhancement of the MET regulon

    James Lee, Leman Simpson ... Lu Bai
    The condensates of activator Met4 are associated with 3D clustering of the MET regulon and its enhanced expression.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Unified bursting strategies in ectopic and endogenous even-skipped expression patterns

    Augusto Berrocal, Nicholas C Lammers ... Michael B Eisen
    1. Chromosomes and Gene Expression

    Connecting Chromatin Structures to Gene Regulation Using Dynamic Polymer Simulations

    Yi Fu, Tianxiao Zhao ... Timothée Lionnet
    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

    Matthew C Pahl, Prabhat Sharma ... Andrew D Wells
    The three-dimensional architecture of the genome in distinct cell types predicts genes and regulatory elements involved in cell function and disease.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    OVO positively regulates essential maternal pathways by binding near the transcriptional start sites in the Drosophila female germline

    Leif Benner, Savannah Muron ... Brian Oliver
    Many well-studied maternal developmental pathways that are required for embryonic development in Drosophila are regulated by the transcription factor OVO in the Drosophila female germline.
    1. Chromosomes and Gene Expression
    2. Medicine

    LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARγ Signaling

    Xianghong Xie, Mingyue Gao ... Xiaojun Liu

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Silke Hauf
    Virginia Tech, United States
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors