Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA

    Zhuo Bi, Yu-Xiang Chen ... Babak Javid
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Chromosomes and Gene Expression

    A genetic toolkit for stable episomal transgenesis in the anaerobic gut parasite Blastocystis ST7-B

    M Rey Toleco, Kevin SW Tan, Mark van der Giezen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration

    Ioannis Grammatikakis, Chosita Norkaew ... Ashish Lal
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    • Compelling
    1. Chromosomes and Gene Expression

    Impacts of DNA methylation on H2A.Z deposition and nucleosome stability

    Rochelle M Shih, Yasuhiro Arimura ... Hironori Funabiki
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Interplay between cohesin and TORC1 links chromosome segregation and gene expression to environmental changes

    Dorian Besson, Sabine Vaur ... Jean-Paul Javerzat
    A conserved kinase network links nutrient sensing to chromosome segregation and gene regulation by modulating cohesin dynamics through phosphorylation.
    Version of Record
    Research Article
    • Important
    • Compelling
    • Convincing
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Contractile perinuclear actomyosin network promotes peripheral and polar chromosome interaction with the mitotic spindle

    Nooshin Sheidaei, John K Eykelenboom ... Tomoyuki U Tanaka
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Transitory enhancement of GATA2 chromatin engagement during early erythroid differentiation

    John W Hobbs, Samuel J Taylor ... Robert A Coleman
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genome reorganization and its functional impact during breast cancer progression

    Kathleen S Metz Reed, Andrew Fritz ... Tom Misteli
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Chromosomes and Gene Expression

    Functional Separation of mRNA Domains Coordinates Pluripotent Cell Behavior

    Ze Yang, Shaoyi Ji ... Mary A Hynes
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    MORC2 mediates transcriptional regulation through liquid-liquid phase separation

    Yanshen Zhang, Weiya Xu ... Yihui Bi
    The dynamic internal fluidity of nuclear MORC2 condensates, rather than their mere assembly, is strictly required for transcriptional regulation and is selectively disrupted by neuropathy-linked mutations.
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Highlights

    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Chromosomes: Finding a role for non-coding DNA in trypanosomes

    Markus R Schmidt
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromosomes: Exploring a crossroads in the aging process

    Kiyan Shabestary, Daniel E Gottschling
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Homologous Recombination: Snapshot of an intermediate structure

    Akira Shinohara

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Adèle L Marston
    University of Edinburgh, United Kingdom
  3. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  4. See more editors