Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Structural Biology and Molecular Biophysics

   Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

   Liza Dahal, Thomas GW Graham ... Xavier Darzacq

   Type II nuclear receptors do not always compete for a limiting pool of their obligate partner RXRa.
2. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   A whole-organism landscape of X-inactivation in humans

   Björn Gylemo, Maike Bensberg, Colm E Nestor
3. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Dissociation of the nuclear basket triggers chromosome loss in aging yeast

   Mihailo Mirkovic, Jordan McCarthy ... Yves Barral
4. 1. Chromosomes and Gene Expression
   2. Physics of Living Systems

   Cluster size determines morphology of transcription factories in human cells

   Massimiliano Semeraro, Giuseppe Negro ... Davide Marenduzzo
5. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Telomere length sensitive regulation of interleukin receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

   Ananda Kishore Mukherjee, Subhajit Dutta ... Shantanu Chowdhury

   Telomere-sensitive regulation of IL1R1 by the shelterin protein TERF2 modulates tumour macrophage inflitration in triple-negative breast cancer.
6. 1. Chromosomes and Gene Expression
   2. Cancer Biology

   Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism

   Priyojit Das, Rebeca San Martin ... Rachel Patton McCord
7. 1. Chromosomes and Gene Expression

   SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing

   Ashwin Govindan, Nicholas K Conrad
8. 1. Cell Biology
   2. Chromosomes and Gene Expression

   TPR is required for cytoplasmic chromatin fragment formation during senescence

   Bethany M Bartlett, Yatendra Kumar ... Wendy A Bickmore

   Evidence is provided suggesting that heterochromatin re-organisation during cell senescence can compromise the structural integrity of the nucleus, leading to activation of an inflammatory process.
9. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   The emergence and evolution of gene expression in genome regions replete with regulatory motifs

   Timothy Fuqua, Yiqiao Sun, Andreas Wagner

   Mutagenizing sequences enriched with promoter motifs creates gene expression de novo, and helps to understand promoter logic, regulatory evolution, and the birth of de novo genes.
10. 1. Chromosomes and Gene Expression
    2. Developmental Biology

    N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

    Valentin Babosha, Natalia Klimenko ... Oksana Maksimenko

    N‑terminus of MSL1 protein, involved in dosage compensation in Drosophila, is required for the interaction with non-coding roX2 RNA and the assembly of the complex on the male X chromosome.