Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression

   An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning

   Ingrid Ehrmann et al.

   Cell division by meiosis during sperm production depends on expression of an RNA-binding protein that prevents abnormal RNA-processing pathways.
2. 1. Chromosomes and Gene Expression
   2. Structural Biology and Molecular Biophysics

   CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair

   Oliver J Wilkinson et al.

   Structural and biochemical analysis of human CtIP provides new insights into DNA break recognition, binding and bridging during homologous recombination.
3. 1. Chromosomes and Gene Expression

   PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells

   Shuchi Agrawal Singh et al.

   A key transcription-factor for osteogenic differentiation, PLZF, acts as a transcriptional activator by binding to active developmental enhancers and facilitates mediator recruitment, but is not involved in enhancer looping.
4. 1. Chromosomes and Gene Expression

   Factors affecting template switch recombination associated with restarted DNA replication

   Manisha Jalan et al.
5. 1. Chromosomes and Gene Expression
   2. Structural Biology and Molecular Biophysics

   A conserved filamentous assembly underlies the structure of the meiotic chromosome axis

   Alan M V West et al.
6. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   The elemental mechanism of transcriptional pausing

   Jason Saba et al.

   Biochemical analyses of transcription complexes, including kinetic studies and probes of translocational and conformational states, establish the elemental mechanism of pausing, which underlies regulation of gene expression in all organisms.
7. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Fine-mapping cis-regulatory variants in diverse human populations

   Ashley Tehranchi et al.

   A map of the genetic variants affecting chromatin accessibility in 1000 individuals from 10 diverse populations reveals how cis-regulatory variants impact transcription and disease.
8. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

   Michael Habig et al.

   Female-inherited supernumerary chromosomes that lack a male-inherited homolog are transmitted to all meiotic products instead of the expected half, which indicates an additional amplification of unpaired chromosomes during meiosis.
9. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Cisplatin-induced DNA double-strand breaks promote meiotic chromosome synapsis in PRDM9-controlled mouse hybrid sterility

   Liu Wang et al.

   The exogenous DNA DSBs improve meiotic chromosome pairing in mouse inter-subspecific hybrids, thus providing an evidence for a DSB-dependent mechanism of the PRDM9-controlled synapsis failure and infertility.
10. 1. Chromosomes and Gene Expression
    2. Developmental Biology

    Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility

    Mehdi Goudarzi et al.