Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife publishes research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Chromosomes and Gene Expression

    Wolbachia action in the sperm produces developmentally deferred chromosome segregation defects during the Drosophila mid-blastula transition

    Brandt Warecki, Simon William Abraham Titen ... William Sullivan
    Differentiation of mitotic errors occurring during late embryonic development from the well-characterized first division defects provides new insight into the mechanisms of Wolbachia-induced cytoplasmic incompatibility.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Global chromatin mobility induced by a DSB is dictated by chromosomal conformation and defines the HR outcome

    Fabiola García Fernández, Etienne Almayrac ... Emmanuelle Fabre
    A designed system to track homologous recombination (HR) in vivo demonstrates the importance of chromosome organization in the induction of global mobility in response to double-strand breaks and characterizes the role of two types of global motility in HR.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    STAG2 promotes the myelination transcriptional program in oligodendrocytes

    Ningyan Cheng, Guanchen Li ... Hongtao Yu
    Brain-specific inactivation of cohesin-STAG2 in the mouse causes myelination defects, thus implicating hypomyelination as a contributing factor to cohesinopathy and establishing oligodendrocytes as a cell system to probe the physiological function of cohesin-mediated genome folding.
    1. Chromosomes and Gene Expression

    Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays

    Makoto M Yoshida, Kazuhisa Kinoshita ... Tatsuya Hirano
    The pentameric condensin II complex is equipped with a multilayered, self-regulatory mechanism that supports mitotic chromosome assembly.

Senior editors

  1. James Manley
    Columbia University, United States
  2. Jessica Tyler
    Weill Cornell Medicine, United States
  3. K VijayRaghavan
    K VijayRaghavan
    National Centre for Biological Sciences, Tata Institute of Fundamental Research, India
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