Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression

    Transcriptional inhibition after irradiation occurs preferentially at highly expressed genes in a manner dependent on cell cycle progression

    Zulong Chen, Xin Wang ... Jessica K Tyler
    Genetic, cellular, and molecular analyses reveal that the reduced abundance of total nascent transcripts that occurs after irradiation is largely due to the repression of histone and rRNA encoding genes.
    1. Chromosomes and Gene Expression

    An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression

    Chileleko Siachisumo, Sara Luzzi ... David J Elliott
    A family of RNA binding proteins that diverged 200 million years ago have parallel roles in protecting the transcriptomic integrity of ultra-long exons within their respective cell types.
    1. Chromosomes and Gene Expression

    The zinc-finger transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay

    Moran Kelbert, Antonio Jordán-Pla ... Mordechai Choder
    Class-specific transcription factor links transcription backtracking with cytoplasmic mRNA decay via co-transcriptional interaction with nascent transcripts.
    1. Chromosomes and Gene Expression

    Transcription factor condensates, 3D clustering, and gene expression enhancement of the MET regulon

    James Lee, Leman Simpson ... Lu Bai
    The condensates of activator Met4 are associated with 3D clustering of the MET regulon and its enhanced expression.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Unified bursting strategies in ectopic and endogenous even-skipped expression patterns

    Augusto Berrocal, Nicholas C Lammers ... Michael B Eisen

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Silke Hauf
    Virginia Tech, United States
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors