Chromosomes and Gene Expression

Latest articles

1. 1. Cell Biology
   2. Chromosomes and Gene Expression

   A compartmentalized signaling network mediates crossover control in meiosis

   Liangyu Zhang et al.

   A regulatory circuit that localizes to the synaptonemal complex, a liquid crystalline compartment between chromosomes, ensures crossing-over while limiting the number of crossovers between homologous chromosomes during meiosis.
2. 1. Chromosomes and Gene Expression

   A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans

   Wei Jiang et al.

   A gene regulatory program regulating thermal stress response and organismic death.
3. 1. Chromosomes and Gene Expression
   2. Structural Biology and Molecular Biophysics

   The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h

   Nathan Gamarra et al.
4. 1. Chromosomes and Gene Expression
   2. Genomics and Evolutionary Biology

   Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

   Sona Gregorova et al.

   Prdm9-generated meiotic asynapsis of homologous chromosomes in mouse subspecific hybrids causes hybrid sterility and can be reversed by introducing random stretches of consubspecific sequence (≥ 27Mb) on four chromosomes most sensitive to asynapsis.
5. 1. Chromosomes and Gene Expression

   A gene-specific T2A-GAL4 library for Drosophila

   Pei-Tseng Lee et al.

   A library of a thousand gene-specific intronic GAL4 insertions was generated, which caused a severe loss of function, permitted the assessing of gene expression, allowed the rescue of mutated gene with UAS-cDNA constructs, and provided a tool for the reversion of mutant phenotypes in specific cells or tissues.
6. 1. Chromosomes and Gene Expression

   MCM2–7-dependent cohesin loading during S phase promotes sister-chromatid cohesion

   Ge Zheng et al.

   Systematic analyses of DNA replication machinery components in human cells reveal a requirement of MCM-dependent de novo loading or mobilization of cohesin at replication forks in establishing sister-chromatid cohesion.
7. 1. Chromosomes and Gene Expression

   The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome

   Emma A Morrison et al.
8. 1. Chromosomes and Gene Expression

   Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts

   Jason C Bell et al.
9. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Codon choice directs constitutive mRNA levels in trypanosomes

   Janaina de Freitas Nascimento et al.

   The information for mRNAs expression level is set by codon choice in trypanosomes and requires translation to be interpreted into a turnover rate.
10. 1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    ICE1 promotes the link between splicing and nonsense-mediated mRNA decay

    Thomas D Baird et al.

    A whole-genome siRNA screen identifies ICE1 as a factor required for accurate sensing and quality control of mRNAs containing premature stop codons.