Chromosomes and Gene Expression

Latest articles

1. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation during early hypoxia

   Fransky Hantelys et al.
2. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in C. elegans

   Teresa W Lee et al.
3. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126

   Nealia CM House et al.
4. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

   Elias T Friman et al.

   OCT4 and SOX2 display partially independent activity to regulate chromatin accessibility, and highly dynamic activity of OCT4 is required throughout the cell cycle to maintain pluripotency enhancer accessibility.
5. 1. Chromosomes and Gene Expression

   An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning

   Irene Díaz-López et al.

   The ES6S region of the small subunit ribosome makes a place for the threading and secondary structure unwinding of mRNA, which regulates genome-wide translation.
6. 1. Cell Biology
   2. Chromosomes and Gene Expression

   RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster

   Wilbur Kyle Mills et al.

   Sperm production and male fertility in Drosophila melanogaster depend on transcripts generated from the AAGAG(n) repeated satellite DNA within primary spermatocytes.
7. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   The DNA-binding protein HTa from Thermoplasma acidophilum is an archaeal histone analog

   Antoine Hocher et al.

   In Thermoplasma acidophilum, an archaeon without histones, a DNA-binding protein acquired from bacteria via horizontal gene transfer mediates histone-like chromatin architecture.
8. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist

   Kevin W Ng et al.

   An ancient integration of an endogenous retroelement in the gene encoding PD-L1 is exapted to generate a soluble form that antagonises the suppressive function of the membrane-bound form.
9. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells

   Masahiro Oka et al.

   A key molecule that connects leukemogenic proteins to aberrant HOX gene regulation turned out to be a nuclear export factor, CRM1.
10. 1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Chromatinization of Escherichia coli with archaeal histones

    Maria Rojec et al.

    Escherichia coli is surprisingly tolerant to chromatinization by archaeal histones, suggesting that histones can become established as ubiquitous chromatin proteins without interfering critically with some key DNA-templated processes.