Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife publishes research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Analysis of long and short enhancers in melanoma cell states

    David Mauduit et al.
    Multi-level massively parallel reporter assays (H3K27ac, ATAC and short tiles) in a panel of melanoma cell lines, together with a deep learning model, reveal location, multiplicity and grammar of subtype specific enhancers.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    RNase III-mediated processing of a trans-acting bacterial sRNA and its cis-encoded antagonist

    Sarah Lauren Svensson, Cynthia Mira Sharma
    Functional characterization of a pair of cis-encoded antisense RNAs reveals a role for RNase III and antisense regulation in the biogenesis and regulatory activity of a bacterial virulence factor-regulating small RNA.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling

    Jugal Mohapatra et al.
    A technology to produce homogenously poly-ADP-ribosylated proteins reveals key molecular mechanisms that govern ATP-dependent chromatin remodeling activity at DNA damage sites.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb

    Fang Huang et al.
    Cyclin T1 phosphorylation determines levels of P-TEFb via stabilizing interactions between cyclin T1 and CDK9.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    High rates of evolution preceded shifts to sex-biased gene expression in Leucadendron, the most sexually dimorphic angiosperms

    Mathias Scharmann et al.
    In the dioecious plant genus Leucadendron, shifts to sex-biased gene expression occurred predominantly in genes with ancestrally high rates of expression evolution, and were not correlated with morphology.

Senior editors

  1. James Manley
    Columbia University, United States
  2. Gisela Storz
    National Institute of Child Health and Human Development, United States
  3. Jessica Tyler
    Weill Cornell Medicine, United States
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