Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females

   Bretta Hixson et al.

   RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.
2. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory

   Bethany Sump et al.
3. 1. Chromosomes and Gene Expression

   DNA-PK promotes DNA end resection at DNA double strand breaks in G₀ cells

   Faith C Fowler et al.
4. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Transcription elongation is finely tuned by dozens of regulatory factors

   Mary Couvillion et al.
5. 1. Chromosomes and Gene Expression
   2. Neuroscience

   Cohesin-dependence of neuronal gene expression relates to chromatin loop length

   Lesly Calderon et al.

   Cohesin is required for the expression of neuronal genes that engage in long chromatin loops, while short-range enhancer-promoter loops can form in the absence of cohesin.
6. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor targeting therapies

   Justin H Hwang et al.
7. 1. Chromosomes and Gene Expression

   Inositol polyphosphate multikinase physically binds to the SWI/SNF complex and modulates BRG1 occupancy in mouse embryonic stem cells

   Jiyoon Beon et al.

   Inositol polyphosphate multikinase physically binds to the core subunits of SWI/SNF complex and plays an important role in regulating BRG1 occupancy and BRG-mediated chromatin accessibility in mouse embryonic stem cells.
8. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Enhanced C/EBPβ function promotes hyperplastic versus hypertrophic fat tissue growth and prevents steatosis in response to high-fat diet feeding

   Christine Müller et al.

   Gene regulation by C/EBPβ determines how surplus of dietary fat is stored, which has consequences for metabolic health.
9. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

   Michela Zaffagni et al.

   In the context of SARS-CoV-2 infection, Nsp14 alters gene expression of the host cell through the interaction with the cellular enzyme IMPDH2.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genetic loci and metabolic states associated with murine epigenetic aging

    Khyobeni Mozhui et al.

    Age-dependent changes in DNA methylation are tightly coupled to the metabolic state, and is partly under genetic regulation, and longer lifespan is associated with lower epigenetic entropy at CpGs that increase in methylation with age.