Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment

   Yukiko Imai et al.

   Biochemical and genetic approaches uncover a chromatin remodeler for PRDM9 binding and the parallel local epigenetic modification of cytosines in mouse spermatocytes.
2. 1. Chromosomes and Gene Expression

   Exploring chromosomal structural heterogeneity across multiple cell lines

   Ryan R Cheng et al.

   Chromosomal structural ensembles are fluid yet are cell-type-specific, despite apparent disorder, appropriate collective variables uncover evidence of structural transitions associated with gene activity and cell differentiation.
3. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells

   Xiao Ling Li et al.
4. 1. Chromosomes and Gene Expression

   The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway

   Qinyu Hao et al.

   Cell cycle phase-specifically induced long non-coding RNAs regulate cell proliferation by modulating crucial cell signaling pathways.
5. 1. Chromosomes and Gene Expression
   2. Plant Biology

   A new role for histone demethylases in the maintenance of plant genome integrity

   Javier Antunez-Sanchez et al.
6. 1. Chromosomes and Gene Expression

   Telomerase biogenesis requires a novel Mex67 function and a cytoplasmic association with the Sm₇ complex

   Yulia Vasianovich et al.
7. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

   Rozenn Riou et al.
8. 1. Chromosomes and Gene Expression
   2. Neuroscience

   Conditional protein tagging methods reveal highly specific subcellular distribution of ion channels in motion-sensing neurons

   Sandra Fendl et al.
9. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor

   Gabrielle E Giese et al.

   Metabolic activity of the methionine/S-adenosylmethionine cycle is sensed and transcriptionally regulated by a nuclear hormone receptor in Caenorhabditis elegans in order to maintain metabolic homeostasis in a tightly controlled regime.
10. 1. Cancer Biology
    2. Chromosomes and Gene Expression

    Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B

    Pieter A Roelofs et al.

    The antiviral and genomic DNA deaminase APOBEC3B is repressed in normal cells by PRC1.6/E2F6 and DREAM/E2F4 complexes and deregulation of this axis provides a unifying mechanism for overexpression in cancer.