Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   High rates of evolution preceded shifts to sex-biased gene expression in Leucadendron, the most sexually dimorphic angiosperms

   Mathias Scharmann et al.

   In the dioecious plant genus Leucadendron, shifts to sex-biased gene expression occurred predominantly in genes with ancestrally high rates of expression evolution, and were not correlated with morphology.
2. 1. Chromosomes and Gene Expression
   2. Plant Biology

   Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin

   Jaemyung Choi et al.
3. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   RNase III-mediated processing of a trans-acting bacterial sRNA and its cis-encoded antagonist

   Sarah Lauren Svensson, Cynthia Mira Sharma
4. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts

   Calvin Jon A Leonen et al.

   Chemically sumoylated histone H4 shows negative biochemical crosstalk with gene-activating histone acetylation and methylation marks, and directly inhibits RNA polymerase II-mediated gene transcription.
5. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb

   Fang Huang et al.
6. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   Pathway dynamics can delineate the sources of transcriptional noise in gene expression

   Lucy Ham et al.

   There are fundamental limits to what can be learned about the origins of transcriptional noise from gene expression data alone, which can be overcome by simultaneously quantifying the abundances of linked molecular species.
7. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells

   Sarah G Swygert et al.

   Using a yeast model of quiescence, it was demonstrated that dramatic changes in local chromatin fiber folding can occur under physiological conditions to regulate cellular processes.
8. 1. Chromosomes and Gene Expression

   Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis

   Hanumanthu BD Prasada Rao et al.

   Cytological analyses combined with in vitro liposome reconstitution reveal that yeast SUN domain protein, Mps3, shows meiosis-specific phosphorylation in the luminal region of the nuclear envelope during meiosis for chromosome motion and nuclear envelope remodelling.
9. 1. Chromosomes and Gene Expression

   DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks

   Shalini Aricthota, Devyani Haldar

   Sirtuin, Hst4 is a novel DDK kinase target, which is modified and degraded in response to replication stress, increasing H3K56 acetylation, to stabilize DNA replication forks via fork protection complex which maintains genome stability and has potential in cancer therapeutics.
10. 1. Chromosomes and Gene Expression
    2. Medicine

    Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia

    Tamara Garrido-Gomez et al.

    The in vivo transcriptomic fingerprint encoding defective decidualization comprises 120 genes associated with an imbalance hormonal signaling in the decidual endometria of women who developed severe preeclampsia.