Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Genome reorganization and its functional impact during breast cancer progression

   Kathleen S Metz Reed, Andrew Fritz ... Tom Misteli
2. 1. Chromosomes and Gene Expression

   Functional Separation of mRNA Domains Coordinates Pluripotent Cell Behavior

   Ze Yang, Shaoyi Ji ... Mary A Hynes
3. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   MORC2 mediates transcriptional regulation through liquid-liquid phase separation

   Yanshen Zhang, Weiya Xu ... Yihui Bi

   The dynamic internal fluidity of nuclear MORC2 condensates, rather than their mere assembly, is strictly required for transcriptional regulation and is selectively disrupted by neuropathy-linked mutations.
4. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends

   Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
5. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   Lineage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors

   William Salvidge, Chris Brimson ... Chris Thompson

   Experiments and mathematical modelling show cell fate in Dictyostelium discoideum partly depends on cell-cycle phase, but also on stochastic gene-expression variability which enhances robustness of developmental responses to cell-cycle perturbation.
6. 1. Chromosomes and Gene Expression

   Single-domain antibody inhibitors target the coiled coil arms of the Bacillus subtilis SMC complex

   Ophélie J Gosselin, Michael Taschner ... Stephan Gruber

   A screen using in vitro-selected synthetic nanobodies identified inhibitors of SMC protein function in bacterial cells, revealing a coiled coil region as a vital component of the chromosome-folding machinery.
7. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis

   Adam Kim, Megan R McMullen ... Srinivasan Dasarathy
8. 1. Chromosomes and Gene Expression

   Uncoupling the TFIIH Core and Kinase Modules Leads To Misregulated RNA Polymerase II CTD Serine 5 Phosphorylation

   Gabriela Giordano, Robin Buratowski ... Stephen Buratowski
9. 1. Chromosomes and Gene Expression

   Identification of the regulatory elements and protein substrates of lysine acetoacetylation

   Qianyun Fu, Terry Nguyen ... Y George Zheng

   A newly developed chemo-immunological strategy enabled detection of acetoacetate-mediated lysine acetoacetylation, identified the associated regulatory enzymes, and revealed its distinct biological functions and physiological significance.
10. 1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    The long non-coding RNA Dreg1 is required for optimal ILC2 development

    Sara Quon, Adelynn Tang ... Rhys Allan

    A Gata3 enhancer-embedded long non-coding RNA, Dreg1, was identified as being specifically required for optimal group 2 innate lymphoid cell development.