Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR

   Hans Tobias Gustafsson, Lucas Ferguson ... Oliver J Rando
2. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Major nuclear locales define nuclear genome organization and function beyond A and B compartments

   Omid Gholamalamdari, Tom van Schaik ... Andrew S Belmont

   New insights into nuclear genome organization were generated by comparing genome localization relative to three major nuclear locales- nuclear lamina, nuclear speckles, and nucleoli- across several human cell lines.
3. 1. Chromosomes and Gene Expression

   SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing

   Ashwin Govindan, Nicholas K Conrad

   SFSWAP was identified in a genetic screen to negatively regulate splicing of OGT and other mRNAs primarily by regulating intron retention and exon skipping.
4. 1. Chromosomes and Gene Expression

   Identification of the Regulatory Elements and Protein Substrates of Lysine Acetoacetylation

   Qianyun Fu, Terry Nguyen ... Y George Zheng
5. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

   Artem K Velichko, Nadezhda V Petrova ... Omar L Kantidze

   Treacle condensation, driven by alternating charge blocks, facilitates interactions with transcription factors to spatially segregate ribosomal RNA synthesis and processing, while also recruiting TOPBP1 for activation of the rDNA damage response.
6. 1. Chromosomes and Gene Expression
   2. Physics of Living Systems

   A mathematical model clarifies the ABC Score formula used in enhancer-gene prediction

   Joseph Nasser, Kee-Myoung Nam, Jeremy Gunawardena
7. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Broad-spectrum immune suppression encoded in self-amplifying RNA enables non-cytotoxic, non-immunostimulatory, externally controllable transgene expression

   Tony KY Lim, Anne Ritoux ... Ewan St John Smith
8. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations

   Lucas Inchausti, Lucía Bilbao ... Pablo Smircich
9. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

   Gülnihal Kavaklioglu, Alexandra Podhornik ... Christian Seiser

   DNA hypomethylation in human tumor cells results in the activation of the LINE-1-derived RNA-binding protein L1TD1 and its interactions with LINE-1 transposons.
10. 1. Chromosomes and Gene Expression

    Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain

    Darshika Bohra, Zubairul Islam ... Dimple Notani