Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila

   Luke Stephen Tain et al.

   Multi-omic profiling of gene expression in response to reduced insulin/IGF-like-signalling reveals tissue-specific regulation of DNA damage and lysosomal mannosidase regulation of tissue homeostasis as pro-longevity responses.
2. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

   Thomas J Etheridge et al.
3. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Channel Nuclear Pore Complex subunits are required for transposon silencing in Drosophila

   Marzia Munafò et al.
4. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Coordination between nucleotide excision repair and specialized polymerase DnaE2 action enables DNA damage survival in non-replicating bacteria

   Asha Mary Joseph et al.
5. 1. Chromosomes and Gene Expression
   2. Medicine

   Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells

   Karthik Amudhala Hemanthakumar et al.

   Endothelial dysfunction due to cardiovascular disease risk factors explained by cardiac endothelial cell transcriptome remodelling.
6. 1. Chromosomes and Gene Expression
   2. Medicine

   Cardiovascular Disease: Exploring risk factors at the molecular level

   Martina Rudnicki, Tara L Haas

   Risk factors for cardiovascular diseases trigger molecular changes that harm the endothelial cells in the heart, but exercise can suppress these effects.
7. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   Morphological and genomic shifts in mole-rat 'queens' increase fecundity but reduce skeletal integrity

   Rachel A Johnston et al.
8. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Stress resets ancestral heritable small RNA responses

   Leah Houri-Zeevi et al.

   Various types of stress reset heritable small RNA responses through the function of the p38 MAPK pathway, the transcription factor SKN-1/Nrf2, and the MET-2/SETDB1 putative histone methyltransferase.
9. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   Increased longevity due to sexual activity in mole-rats is associated with transcriptional changes in the HPA stress axis

   Arne Sahm et al.

   The fact that sexual activity/reproduction doubles the lifespan of certain rodent species is most likely linked to critical changes in the regulation of the hypothalamic–pituitary–adrenal stress axis.
10. 1. Chromosomes and Gene Expression

    Promoter-specific changes in initiation, elongation, and homeostasis of histone H3 acetylation during CBP/p300 inhibition

    Emily Hsu et al.

    CBP/p300 acetylation of histone H3 at promoters and enhancers stimulates transcriptional elongation through recruitment of the super-elongation complex and BRD4.