Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

    Gülnihal Kavaklioglu, Alexandra Podhornik ... Christian Seiser
    DNA hypomethylation in human tumor cells results in the activation of the LINE-1-derived RNA-binding protein L1TD1 and its interactions with LINE-1 transposons.
    1. Chromosomes and Gene Expression

    Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain

    Darshika Bohra, Zubairul Islam ... Dimple Notani
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Telomeres control human telomerase (hTERT) expression through non-telomeric TRF2

    Antara Sengupta, Soujanya Vinayagamurthy ... Shantanu Chowdhury
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    MagIC-Cryo-EM: Structural determination on magnetic beads for scarce macromolecules in heterogeneous samples

    Yasuhiro Arimura, Hide A Konishi, Hironori Funabiki
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression

    Yoshinori Kohwi, Xianrong Wong ... Terumi Kohwi-Shigematsu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity

    Shihui Chen, Carolyn Marie Phillips
    RNA interference pathways are spatially and temporally organized during Caenorhabditis elegans embryogenesis, with the Argonaute protein NRDE-3 playing distinct roles in regulating genes in different cell types and developmental stages.
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli

    Irina Kalita, Ira Alexandra Iosub ... Meriem El Karoui
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Transcription: The plusses and minuses of DNA torsion

    Steven Henikoff, David L Levens
    A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.
    Version of Record
    Insight
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation

    Li He, Jiayu Wen, Qi Dai
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Interplay of YEATS2 and GCDH mediates histone crotonylation and drives EMT in head and neck cancer

    Deepak Pant, Parik Kakani ... Sanjeev Shukla
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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Highlights

    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Navigating the secrets of COMPASS

    Karolin Luger, Jonathan W Markert
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Reality check for transposons

    Julie Brind'Amour, Dixie L Mager
    1. Chromosomes and Gene Expression

    Painting chromosomes in the nucleus

    Cori K Cahoon, Diana E Libuda

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Silke Hauf
    Virginia Tech, United States
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors