Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression

   Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo

   Suna Gulay et al.

   Interactions of eIF4A and eIF4E with specific amino-acids in the N-terminal domain of DEAD-box helicase Ded1 enhance bulk polysome assembly and translation of reporter mRNAs with structured leaders in vivo.
2. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   Coverage-dependent bias creates the appearance of binary splicing in single cells

   Carlos F Buen Abad Najar et al.
3. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   The Role of Rif1 in telomere length regulation is separable from its role in origin firing

   Calla B Shubin, Carol W Greider
4. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner

   Stefan Golfier et al.

   Reconstitution of DNA loop extrusion in cellular contexts using Xenopus egg extracts shows that condensin extrudes DNA loops non-symmetrically in metaphase, whereas cohesin extrudes DNA loops symmetrically in interphase.
5. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition

   Michael Zavortink et al.
6. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes

   Alisha Schlichter et al.

   A SWI/SNF-family chromatin remodeling subcomplex from yeast is identified (RSC1) that is specialized to slide nucleosomes residing on DNA sequences that confer partial nucleosome unwrapping, with assistance from accessory factors.
7. 1. Chromosomes and Gene Expression
   2. Physics of Living Systems

   Chromosome organization by one-sided and two-sided loop extrusion

   Edward J Banigan et al.

   Seemingly contradictory findings of single-molecule and in vivo experiments on a major mechanism of chromosome organization are reconciled by computationally investigating mechanisms of loop extrusion that are consistent with both.
8. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Spatial inter-centromeric interactions facilitated the emergence of evolutionary new centromeres

   Krishnendu Guin et al.

   Proximity and homology guided inter-chromosomal translocations drive karyotype evolution.
9. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

   Gernot Wolf et al.

   Unbiased ChIP-seq screens and genetic knockouts of large Kruppel associated box zinc finger protein (KRAB-ZFP) clusters reveal that evolutionarily young KRAB-ZFPs play a redundant role in retrotransposon restriction in mice.
10. 1. Chromosomes and Gene Expression

    Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation

    Ava C Carter et al.

    A long noncoding RNA uses viral mimicry to achieve developmental gene silencing across a chromosome.