Chromosomes and Gene Expression

Latest articles

1. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence

   Shou Liu et al.
2. 1. Chromosomes and Gene Expression
   2. Plant Biology

   Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA

   Matthew T Parker et al.

   The expression of Arabidopsis NLR immune response genes is modulated by premature transcription termination, and this has implications for understanding NLR regulation and evolutionary dynamics.
3. 1. Chromosomes and Gene Expression
   2. Structural Biology and Molecular Biophysics

   The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

   Laura Plassart et al.

   Cryo-EM and functional studies reveal how combined action of proteins RPS26/eS26 and RIO1 allows late precursors to the human small ribosomal particle to be matured into fully translation-competent 40S subunits.
4. 1. Chromosomes and Gene Expression

   Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay

   Hiroaki Tachiwana et al.

   A new method using permeabilized cells and recombinant histones enables to analyze histone incorporations at the DNA sequence level.
5. 1. Chromosomes and Gene Expression
   2. Evolutionary Biology

   Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity

   Rachel A Johnston et al.

   In cooperatively breeding Damaraland mole-rats, transitioning to 'queen' results in extensive gene regulatory and morphological remodeling, but also costs to skeletal integrity that scale with reproductive investment.
6. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer

   Carter J Barger et al.

   FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.
7. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Common virulence gene expression in adult first-time infected malaria patients and severe cases

   J Stephan Wichers et al.

   Parasites with pathogenic variant surface antigens are common in adult malaria patients with a naive immune status.
8. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Coordination between nucleotide excision repair and specialized polymerase DnaE2 action enables DNA damage survival in non-replicating bacteria

   Asha Mary Joseph et al.

   Live-cell imaging shows that replication-independent specialized polymerase action is a consequence of lesion processing via NER and impacts cellular survival under stress outside replicative phases of the cell cycle.
9. 1. Chromosomes and Gene Expression

   SAM homeostasis is regulated by CFI_m-mediated splicing of MAT2A

   Anna M Scarborough et al.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Epigenetic analysis of Paget's disease of bone identifies differentially methylated loci that predict disease status

    Ilhame Diboun et al.