Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression

   Translation affects mRNA stability in a codon-dependent manner in human cells

   Qiushuang Wu et al.

   Genomic-profiles and reporters reveal that the three-nucleotide ‘words’ read by the ribosome, codons, have a strong effect on mRNA stability, impacting the homeostatic mRNA and protein levels in human cells.
2. 1. Chromosomes and Gene Expression
   2. Stem Cells and Regenerative Medicine

   MicroRNA-deficient mouse embryonic stem cells acquire a functional interferon response

   Jeroen Witteveldt et al.

   MiRNA-mediated suppression of MAVS expression in embryonic stem cells is necessary to inactivate the type I interferon response.
3. 1. Chromosomes and Gene Expression
   2. Structural Biology and Molecular Biophysics

   Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation

   David Trombley McSwiggen et al.

   Transient DNA interactions by DNA-binding proteins are utilized by herpes simple virus as an alternative route to generate membraneless compartments in the nucleus without invoking phase separation.
4. 1. Chromosomes and Gene Expression

   Asymmetry between the two acidic patches dictates the direction of nucleosome sliding by the ISWI chromatin remodeler

   Robert F Levendosky, Gregory D Bowman
5. 1. Chromosomes and Gene Expression

   Genome Organization: Painting chromosomes in the nucleus

   Cori K Cahoon, Diana E Libuda

   A multiplexed approach to DNA FISH experiments has been used to visualize the three-dimensional organization of chromosomes and specific chromosomal regions in C. elegans..
6. 1. Chromosomes and Gene Expression

   Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

   Haiyang Zhang et al.
7. 1. Chromosomes and Gene Expression

   A multiplexed DNA FISH strategy for assessing genome architecture in Caenorhabditis elegans

   Brandon D Fields et al.

   The design and validation of an oligo-based DNA FISH library that targets the entire Caenorhabditis elegans genome at chromosome, three megabase, and 500 kb scales.
8. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   A combination of transcription factors mediates inducible interchromosomal contacts

   Seungsoo Kim et al.
9. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   A bipartite iron-dependent transcriptional regulation of the tryptophan salvage pathway in Chlamydia trachomatis

   Nick D Pokorzynski et al.

   Analysis of the atypical tryptophan biosynthetic operon of Chlamydia trachomatis revealed the simultaneous regulation of transcriptional initiation and termination by an iron-dependent repressor, expanding known regulatory mechanisms of this pathway.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency

    Maxim Greenberg et al.

    Three-dimensional chromatin architecture facilitates a promoter switch in order to ensure maintained expression of a gene involved in growth during embryonic stem cell differentiation.