Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Medicine

   Gene dosage imbalance disrupts systemic metabolism in the Dp16 Down syndrome mouse model

   Fangluo Chen, Muzna Saqib ... G William Wong
2. 1. Chromosomes and Gene Expression

   UV irradiation alters TFAM binding specificity and compaction of DNA

   Dillon E King, Emily E Beard ... Joel Meyer

   Independent experimental approaches demonstrate changes in TFAM binding to UVC-irradiated DNA, providing a potential mechanism for DNA damage sensing in the mitochondria.
3. 1. Chromosomes and Gene Expression

   Single Domain Antibody Inhibitors Target the Coiled Coil Arms of the Bacillus subtilis SMC complex

   Ophélie Gosselin, Michael Taschner ... Stephan Gruber
4. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

   Yuzhen Liu, Christopher D McGann ... Devin K Schweppe
5. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum

   Todd Lenz, Madle Sirel ... Ulf Ribacke
6. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Dynamic RNA Polymerase compartments organize the transcription of gene clusters

   Yi-Hui Wang, Hannah L Hertz, Wen Tang
7. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration in human cancer cells

   Ravi Kumar, Simon Couly ... Ashish Lal

   Global proteomics and functional analyses reveal that p53-induced ZMAT3 suppresses mitochondrial respiration by inhibiting transcription of a hexokinase, uncovering a role for ZMAT3 in transcription.
8. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   Dietary sulfur amino acid restriction elicits a cold-like transcriptional response in inguinal but not epididymal white adipose tissue of male mice

   Philip MM Ruppert, Aylin S Gueller ... Jan-Wilhelm Kornfeld

   Transcriptomic profiling on liver and adipose depots reveals tissue-specific and beige-fat–convergent responses to methionine restriction and cold, providing a high-quality resource to guide combinatorial lifestyle interventions for metabolic disease research.
9. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations

   Lucas Inchausti, Lucía Bilbao ... Pablo Smircich
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

    Roberta Carloni, Tadhg Devlin ... Robin C Allshire

    Synthetic proteins designed to bind specific repetitive DNA sequences in the Trypanosoma brucei genome allow the identification of proteins enriched over different DNA elements.