Editors for Computational and Systems Biology

We aim to publish studies that use computational methods, models and software to provide important biological insights in all areas of the life sciences. Read the latest research in this subject area.

Senior editors

  1. Naama Barkai

    Naama Barkai

    Senior Editor

    Naama Barkai is a systems and computational biologist interested in how bio-molecular circuits are designed. She joined the Weizmann Institute in 1999, following a post-doc (Princeton) and graduate studies (Hebrew University) in physics. She is currently chair of the Department of Molecular Genetics, and the head of the Azrieli and Kahan Centers for Systems Biology at the Weizmann Institute. In 2013, Barkai was elected to a Vallee Foundation Visiting Professorship and awarded the Abisch Frankel prize.

    Expertise
    Computational and Systems Biology
    Physics of Living Systems
    Research focus
    systems biology
    modeling
    functional genomics
    yeast genetics
    morphogen gradients
    Competing interests statement
    Naama Barkai's main funding sources are from the European Research Council (ERC), the Human Frontier Science Program (HFSP), the Israel Science Foundation (ISF), Minerva, and the Bi-national Science Foundation (BSF). Barkai also serves on the editorial board of Development.
  2. Ronald L Calabrese

    Senior Editor

    Ron Calabrese earned his BS in Biochemistry from Cornell University and a PhD in Neurobiology from Stanford University. He has been on the Faculty of the Department of Biology, Emory University since 1986 and is currently the Samuel Candler Dobbs Professor of Biology and Senior Associate Dean for Research. Calabrese's research focuses on the cellular mechanisms of motor control by central pattern generator (CPG) networks and the importance and implications of individual variation for network function and motor performance. His group uses an invertebrate model system, leeches, and focuses on the CPG that controls the beating of the animals two coordinated hearts. His research closely integrates electrophysiological experiments and computational modeling. They are particularly excited about their discovery, in collaboration with GS Cymbalyuk, that the Na/K pump current contributes to the bursting dynamics of oscillator neurons that pace the CPG, and in their recent eLife publication on output variability across animals and levels in a the leech-heartbeat motor system. Calabrese has been actively engaged in training 12 doctoral students, 2 masters' students, and 22 postdoctoral fellows. In 2017, he received the Award for Education in Neuroscience of the Society for Neuroscience.

    Expertise
    Computational and Systems Biology
    Neuroscience
    Research focus
    motor pattern generation
    neuronal and small networks models
    electrophysiological properties of neurons and synapse
    computational neuroscience
    Experimental organism
    leech
    Competing interests statement
    Over the past 30 years, Ron Calabrese has been consistently supported by NIH R01 grants. Since 2015, Calabrese has been a regular member of the SMI study section of NIH.
  3. Arup K Chakraborty

    Arup K Chakraborty

    Senior Editor

    Arup K Chakraborty is the Robert T Haslam Professor of Chemical Engineering, Physics, Chemistry, and Biological Engineering at MIT. He is the founding Director of MIT’s Institute for Medical Engineering and Science. He is also a founding steering committee member of the Ragon Institute of MIT, MGH, and Harvard, and an Associate Member of the Broad Institute of MIT & Harvard. After obtaining his PhD in chemical engineering and postdoctoral studies, he joined the faculty at the University of California at Berkeley in December 1988. He rose through the ranks, and ultimately served as the Warren and Katherine Schlinger Distinguished Professor and Chair of Chemical Engineering, Professor of Chemistry, and Professor of Biophysics at Berkeley. He was also Head of Theoretical and Computational Biology at Lawrence Berkeley National Laboratory. In September 2005, Chakraborty moved to MIT.

    His entire career has been focused on research at the intersection of disciplines. After an early career in engineering of polymers and catalysts, since 2000 Chakraborty’s work has focused on bringing together immunology and the physical and engineering sciences; more specifically, the intersection of statistical mechanics and immunology. His interests span T-cell signaling, T-cell development and repertoire, and a mechanistic understanding of HIV evolution, antibody evolution, and vaccine design. Chakraborty’s work at the intersection of disciplines has been recognized by numerous honors, including the NIH Director’s Pioneer Award, the EO Lawrence Medal for Life Sciences from the US DOE, the Allan P Colburn and Professional Progress awards from the AIChE, a Dreyfus Teacher-Scholar award, and a National Young investigator award. Chakraborty was elected a member of the National Academy of Sciences and the National Academy of Engineering for completely different bodies of work. He is also a member of the National Academy of Medicine, making him one of 21 individuals who are members of all three branches of the US National Academies. He is a Fellow of the American Academy of Arts & Sciences and the American Association for the Advancement of Science, and serves on the US Defense Science Board. Chakraborty has received four teaching awards at Berkeley and MIT.

    Expertise
    Computational and Systems Biology
    Immunology and Inflammation
    Physics of Living Systems
    Research focus
    computational biology
    immunology
    statistical mechanics
    signaling
    virology
    protein evolution
    Competing interests statement
    Arup Chakraborty is funded by the NIH and the Ragon Institute of MGH, MIT, and Harvard.
  4. Aviv Regev

    Aviv Regev

    Senior Editor

    Aviv Regev is a computational biologist who joined the Broad Institute as a core member and MIT as a faculty member in 2006. Her work investigates how complex molecular networks function and evolve in the face of genetic and environmental changes, over time-scales ranging from minutes to millions of years. Regev received her MSc from Tel Aviv University, studying biology, computer science, and mathematics in the Interdisciplinary Program for the Fostering of Excellence, where she undertook research in both theoretical and experimental biology. She received her PhD in computational biology from Tel Aviv University. Prior to joining the Broad Institute, Regev was a fellow at the Bauer Center for Genomics Research at Harvard University, where she developed new approaches to the reconstruction of regulatory networks and modules from genomic data. Regev is also an associate professor in the Department of Biology at MIT
and director of the Klarman Cell Observatory at the Broad. Regev is the Director of the Cell Circuits Program at the Broad and a lead principal investigator for the Center for Cell Circuits at the Broad Institute, a Center of Excellence in Genomic Science (CEGS). Regev has been a Howard Hughes Medical Institute (HHMI) Early Career Scientist since 2009, and was named a Howard Hughes Medical Institute (HHMI) Investigator in 2013. She is a recipient of the NIH Director’s Pioneer Award, a Sloan fellowship from the Sloan Foundation, the Overton Prize from the International Society for Computational Biology, and the Earl and Thressa Stadtman Scholar Award from the American Society for Biochemistry and Molecular Biology (ASBMB).

    (Image Credit: Maria Nemchuk)

    Expertise
    Computational and Systems Biology
    Genetics and Genomics
    Chromosomes and Gene Expression
    Evolutionary Biology
    Cancer Biology
    Research focus
    systems biology
    molecular networks
    computational biology
    single cell genomics
    regulatory networks
    systems immunology
    gene regulation
    evolution
    Competing interests statement
    Aviv Regev receives funding from the Howard Hughes Medical Institute, the National Institutes of Health, and the Sloan Foundation. She is on the external advisory board of the San Diego Center for Systems Biology, the FAS Center for Systems Biology at Harvard, the Simons Institute for the Theory of Computing, the Jackson Laboratory, the European Molecular Biology Lab (EMBL), the SciLife Lab in Sweden, and ThermoFisher Scientific. She is on the advisory editorial board of Molecular Systems Biology and is an editorial board member of Genome Biology and Development. Regev is a consultant for Syros Phramaceuticals, GenePeeks, and CTIG (Cancer Therapeutics Innovation Group). Regev also worked for several years in the biotech industry in Israel, where she established and directed a bioinformatics research and development team at QBI, a functional genomics company.
  5. Patricia Wittkopp

    Senior Editor

    Patricia Wittkopp received a BS from the University of Michigan, a PhD from the University of Wisconsin, and did postdoctoral work at Cornell University. In 2005, she began a faculty position at the University of Michigan, where she is now an Arthur F Thurnau Professor in the Department of Ecology and Evolutionary Biology, Department of Molecular, Cellular, and Developmental Biology, Center for Computational Medicine and Bioinformatics, and LSA Honors Program. Her research investigates the genetic basis of phenotypic evolution, with an emphasis on the evolution of gene expression. Molecular and developmental biology, population and quantitative genetics, genomics and bioinformatics are integrated in this work. She was a Damon Runyon Cancer Research Fellow, an Alfred P Sloan Research Fellow, and a recipient of a March of Dimes Starter Scholar Award.

    Expertise
    Computational and Systems Biology
    Ecology
    Genetics and Genomics
    Evolutionary Biology
    Research focus
    evolutionary genetics
    evolution and development
    gene expression
    regulatory networks
    allele-specific expression
    Competing interests statement
    Patricia Wittkopp has received research support from the National Institutes of Health, National Science Foundation, March of Dimes, and the Alfred P Sloan Foundation. She is currently an Associate Editor of Molecular Biology and Evolution and Genome Biology and Evolution, and also serves on the Advisory Editorial Board of Trends in Genetics.

Reviewing editors

  1. Timothy Verstynen

    Carnegie Mellon University, United States

    Expertise
    Computational and Systems Biology
    Neuroscience
    Research focus
    cognition
    decision-making
    Experimental organism
    human
  2. Stephen Parker

    University of Michigan, United States

    Expertise
    Genetics and Genomics
    Chromosomes and Gene Expression
    Computational and Systems Biology
    Research focus
    diabetes
    disease susceptibility
    functional genomics
    comparative genomics
    population genomics
    Experimental organism
    human
    mouse
    rat
  3. Chris Ponting

    University of Edinburgh, United Kingdom

    Expertise
    Computational and Systems Biology
    Genetics and Genomics
    Research focus
    evolutionary genomics
    long non-coding RNAs
    functional genomics
    transcriptomics
    Experimental organism
    D. melanogaster
    human
    mouse
  4. Michael Breakspear

    QIMR Berghofer Medical Research Institute, Australia

    Expertise
    Computational and Systems Biology
    Neuroscience
    Research focus
    systems neuroscience
    computational neuroscience
    clinical neuroscience
  5. Christian R Landry

    Universite Laval, Canada

    Expertise
    Computational and Systems Biology
    Evolutionary Biology
    Research focus
    evolutionary genetics
    evolution
    bioinformatics
    cell and systems biology
    yeast genetics
    Experimental organism
    S. cerevisiae
  6. Thorsten Kahnt

    Northwestern University, United States

    Expertise
    Neuroscience
    Computational and Systems Biology
    Research focus
    Neural and computational principles of learning and decision-making
    psychophysics
    computational modeling
    TMS
    fMRI
  7. Nir Ben-Tal

    Tel Aviv University, Israel

    Expertise
    Structural Biology and Molecular Biophysics
    Computational and Systems Biology
    Research focus
    structural bioinformatics
    structure, function and motion in membrane proteins
    protein interactions
  8. Carl T Bergstrom

    University of Washington, United States

    Expertise
    Computational and Systems Biology
    Ecology
    Evolutionary Biology
    Research focus
    game theory
    network science
    evolution
  9. Alexander Borst

    Max Planck Institute of Neurobiology, Germany

    Expertise
    Computational and Systems Biology
    Neuroscience
    Research focus
    visual processing
    systems neuroscience
    computational neuroscience
    Experimental organism
    Drosophila
  10. Ben Cooper

    Mahidol Oxford Tropical Medicine Research Unit, Thailand

    Expertise
    Computational and Systems Biology
    Epidemiology and Global Health
    Research focus
    population biology of communicable diseases
    antimicrobial resistance
    epidemiological methods
  11. Job Dekker

    University of Massachusetts Medical School, United States

    Expertise
    Computational and Systems Biology
    Chromosomes and Gene Expression
    Research focus
    spatial organisation of genomes
    chromatin interaction networks
  12. Michael Doebeli

    University of British Columbia, Canada

    Expertise
    Computational and Systems Biology
    Ecology
    Evolutionary Biology
    Research focus
    mathematical modelling
    evolution of diversity
    social insects
    ecology and evolution of microbial communities
  13. David D Ginty

    Howard Hughes Medical Institute, Harvard Medical School, United States

    Expertise
    Computational and Systems Biology
    Developmental Biology
    Neuroscience
    Research focus
    neurotrophic factors
    peripheral nervous system development
    mechanosensory neurons
    tactile processing
    spinal cord
  14. Mary B Kennedy

    California Institute of Technology, United States

    Expertise
    Biochemistry and Chemical Biology
    Computational and Systems Biology
    Neuroscience
    Research focus
    synaptic plasticity
    synaptic regulation
    biochemical signal transduction networks
    systems biology
  15. Peter Latham

    University College London, United Kingdom

    Expertise
    Computational and Systems Biology
    Neuroscience
    Research focus
    bayesian inference
    network dynamics
    neural coding
    synaptic plasticity
  16. Andrei Lupas

    Max Planck Institute for Developmental Biology, Germany

    Expertise
    Computational and Systems Biology
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    origins and evolution of folded proteins
    coiled coils
    bioinformatics
    transmembrane signal tranduction
    bacterial surface proteins
  17. Andrew Morris

    University of Liverpool, United Kingdom

    Expertise
    Computational and Systems Biology
    Genetics and Genomics
    Research focus
    statistical genetics
    genetic epidemiology
    methodological development
    genome-wide association studies
  18. Richard A Neher

    University of Basel, Switzerland

    Expertise
    Computational and Systems Biology
    Physics of Living Systems
    Evolutionary Biology
    Research focus
    population genetics
    evolution of RNA viruses
    bioinformatics
  19. Molly Przeworski

    Columbia University, United States

    Expertise
    Computational and Systems Biology
    Evolutionary Biology
    Genetics and Genomics
    Research focus
    population genetics
    evolutionary biology
    recombination
    Experimental organism
    primates
  20. Yibing Shan

    DE Shaw Research, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Computational and Systems Biology
    Research focus
    computational structural biology
    signaling
    computational chemistry
    molecular dynamics
  21. Wenying Shou

    Fred Hutchinson Cancer Research Center, United States

    Expertise
    Computational and Systems Biology
    Ecology
    Evolutionary Biology
    Research focus
    evolution of cooperation and multi-level selection
    microbial ecology and evolution
    quantitative experimental biology
    theoretical biology
  22. Cassidy Sugimoto

    Indiana University Bloomington, United States

    Expertise
    Computational and Systems Biology
    Research focus
    scholarly communication
    scientometrics
    gender
    science policy
  23. M Dawn Teare

    University of Sheffield, United Kingdom

    Expertise
    Computational and Systems Biology
    Epidemiology and Global Health
    Research focus
    statistics
    population genetics
    epidemiology
  24. Alfonso Valencia

    Barcelona Supercomputing Center, Spain

    Expertise
    Cancer Biology
    Computational and Systems Biology
    Research focus
    bioinformatics
    structural bioinformatics
    evodevo
    cancer genomics
    text mining
  25. Mark CW van Rossum

    University of Edinburgh, United Kingdom

    Expertise
    Computational and Systems Biology
    Neuroscience
    Research focus
    synaptic plasticity
    noise in neural systems
    the early visual system
    retina
  26. Aleksandra Walczak

    Ecole normale superieure, France

    Expertise
    Computational and Systems Biology
    Physics of Living Systems
    Research focus
    systems biology
    gene regulatory networks
    immune system
    population genetics
    Experimental organism
    zebrafish