Computational and Systems Biology

Latest articles

1. 1. Computational and Systems Biology
   2. Evolutionary Biology

   Eco-evolutionary dynamics of adapting pathogens and host immunity

   Pierre Barrat-Charlaix, Richard A. Neher
2. 1. Cell Biology
   2. Computational and Systems Biology

   circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

   Trine Line Hauge Okholm, Andreas Bjerregaard Kamstrup ... Christian Kroun Damgaard
3. 1. Structural Biology and Molecular Biophysics
   2. Computational and Systems Biology

   MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations

   Johanna K. S. Tiemann, Magdalena Szczuka ... Pierre Poulain
4. 1. Neuroscience
   2. Computational and Systems Biology

   The Recurrent Temporal Restricted Boltzmann Machine Captures Neural Assembly Dynamics in Whole-brain Activity

   Sebastian Quiroz Monnens, Casper Peters ... Bernhard Englitz
5. 1. Computational and Systems Biology

   Perturbation-response analysis of in silico metabolic dynamics in nonlinear regime: Hard-coded responsiveness in the cofactors and network sparsity

   Yusuke Himeoka, Chikara Furusawa
6. 1. Computational and Systems Biology

   Accurate prediction of CDR-H3 loop structures of antibodies with deep learning

   Hedi Chen, Xiaoyu Fan ... Boxue Tian

   A deep learning-based toolkit predicting the 3D structures of monoclonal antibodies and nanobodies outperforms other current computational methods.
7. 1. Medicine
   2. Computational and Systems Biology

   Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning

   Gitanjali Roy, Rameesha Syed ... Michael A. Kalwat
8. 1. Computational and Systems Biology

   Semantical and Geometrical Protein Encoding Toward Enhanced Bioactivity and Thermostability

   Yang Tan, Bingxin Zhou ... Liang Hong
9. 1. Computational and Systems Biology
   2. Medicine

   The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study

   Zachary Shaffer, Roberto Romero ... Nardhy Gomez-Lopez

   The vaginal immunoproteome in pregnancy is more predictive of spontaneous preterm birth (sPTB) than maternal characteristics alone, with sPTB cases showing heightened pro-inflammatory profiles accompanied by reduced levels of antimicrobial proteins/peptides.
10. 1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Benchmarking tRNA-Seq quantification approaches by realistic tRNA-Seq data simulation identifies two novel approaches with higher accuracy

    Tom Smith, Mie Monti ... Lajos Kalmár