Computational and Systems Biology

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Computational and Systems Biology

   PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107

   Holly Fowle et al.
2. 1. Computational and Systems Biology
   2. Structural Biology and Molecular Biophysics

   Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel

   Cathrine Bergh et al.
3. 1. Computational and Systems Biology
   2. Epidemiology and Global Health

   Emerging dynamics from high-resolution spatial numerical epidemics

   Olivier Thomine et al.
4. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   circFL-seq reveals full-length circular RNAs with rolling circular reverse transcription and nanopore sequencing

   Zelin Liu et al.
5. 1. Computational and Systems Biology

   Simplifying the development of portable, scalable, and reproducible workflows

   Stephen R Piccolo et al.

   Descriptions, examples, and tools to enable biologists to use the Common Workflow Language for data processing and to facilitate computational reproducibility.
6. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Linking functional and molecular mechanisms of host resilience to malaria infection

   Tsukushi Kamiya et al.

   With a data-driven mathematical modelling approach, within-host ecological information alone can provide clues on the mechanistic basis of diverse malaria infection outcomes.
7. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   Pathway dynamics can delineate the sources of transcriptional noise in gene expression

   Lucy Ham et al.
8. 1. Computational and Systems Biology
   2. Neuroscience

   Optimal plasticity for memory maintenance during ongoing synaptic change

   Dhruva V Raman, Timothy O'Leary

   Simple mathematical reasoning shows that the large amount of synaptic turnover seen in many parts of the brain is in fact optimal for memory retention.
9. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Two different cell-cycle processes determine the timing of cell division in Escherichia coli

   Alexandra Colin et al.
10. 1. Computational and Systems Biology
    2. Genetics and Genomics

    Information content differentiates enhancers from silencers in mouse photoreceptors

    Ryan Z Friedman et al.

    Silencers and enhancers targeted by a common transcription factor in photoreceptors are distinguished by the number and diversity of binding transcription factor binding sites they contain.