Computational and Systems Biology

Computational and Systems Biology

eLife reviews research involving the use of methods, models and software. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Genetics and Genomics
    2. Computational and Systems Biology

    JAX Animal Behavior System (JABS): A genetics informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse

    Anshul Choudhary, Brian Q Geuther ... Vivek Kumar
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Cancer Biology

    Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML

    Jessica Whittle, Stefan Meyer ... Mudassar Iqbal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Computational and Systems Biology
    2. Neuroscience

    Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila

    Jayati Gera, Marishia Agard ... Meet Zandawala
    A multi-pronged approach reveals that ion transport peptide neuropeptide acts through the guanylate cyclase receptor Gyc76C to coordinate osmotic and metabolic homeostasis across multiple tissues in Drosophila.
    1. Computational and Systems Biology

    Raw signal segmentation for estimating RNA modification from Nanopore direct RNA sequencing data

    Guangzhao Cheng, Aki Vehtari, Lu Cheng
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    Motor biases reflect a misalignment between visual and proprioceptive reference frames

    Tianhe Wang, Ryan J Morehead ... Jonathan S Tsay
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    The time course of visuo-semantic representations in the human brain is captured by combining vision and language models

    Boyan Rong, Alessandro Thomas Gifford ... Radoslaw Martin Cichy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Computational and Systems Biology

    MorphoNet 2.0: An innovative approach for qualitative assessment and segmentation curation of large-scale 3D time-lapse imaging datasets

    Benjamin Gallean, Tao Laurent ... Emmanuel Faure
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Computational and Systems Biology
    2. Neuroscience

    Correlation detection as a stimulus computable account for audiovisual perception, causal inference, and saliency maps in mammals

    Cesare V Parise
    Optimal cue integration, Bayesian Causal Inference, spatial orienting, speech illusions and other key phenomena in audiovisual perception naturally emerge from the collective behavior of a population of Multisensory Correlation Detector.
    1. Ecology
    2. Computational and Systems Biology

    vassi – verifiable, automated scoring of social interactions in animal groups

    Paul Nührenberg, Aneesh PH Bose, Alex Jordan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Human EEG and artificial neural networks reveal disentangled representations and processing timelines of object real-world size and depth in natural images

    Zitong Lu, Julie D Golomb
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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Highlights

    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

    Submit to our latest special issue in systems genetics

    1. Cancer Biology
    2. Computational and Systems Biology

    eLife publishes final papers from the Reproducibility Project: Cancer Biology

    Timothy M Errington, Maya Mathur ... Brian A Nosek
    1. Computational and Systems Biology

    International aspects of bioRxiv preprints

    Richard J Abdill, Elizabeth M Adamowicz, Ran Blekhman

Senior editors

  1. Alan Moses
    University of Toronto, Canada
  2. Aleksandra Walczak
    Ecole Normale Superieure, France
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