Computational and Systems Biology

Latest articles

1. 1. Computational and Systems Biology
   2. Immunology and Inflammation

   Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

   George Ueda et al.

   De novo protein nanoparticles were designed from scratch to present viral glycoprotein antigens, providing a systematic way to study the influence of antigen presentation geometry on immune response.
2. 1. Computational and Systems Biology
   2. Developmental Biology

   A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

   Bjoern Gaertner et al.
3. 1. Computational and Systems Biology
   2. Neuroscience

   Stable task information from an unstable neural population

   Michael E Rule et al.

   Analysis and modelling of sensorimotor neural activity shows how ongoing plasticity and appropriately tuned weights can cope with substantial ongoing changes in the neural code.
4. 1. Computational and Systems Biology
   2. Neuroscience

   Dopamine role in learning and action inference

   Rafal Bogacz

   A mathematical model describes the function of dopaminergic neurons in both learning and action planning.
5. 1. Computational and Systems Biology
   2. Neuroscience

   A unified computational model for cortical post-synaptic plasticity

   Tuomo Mäki-Marttunen et al.
6. 1. Cancer Biology
   2. Computational and Systems Biology

   Identifying prostate cancer and its clinical risk in asymptomatic men using machine learning of high dimensional peripheral blood flow cytometric natural killer cell subset phenotyping data

   Simon P Hood et al.

   Diagnosing the presence and clinical significance of prostate cancer can be achieved using AI-based analysis of peripheral blood natural killer (NK) cell subset profiles.
7. 1. Computational and Systems Biology
   2. Neuroscience

   A sensorimotor model shows why a spectral jamming avoidance response does not help bats deal with jamming

   Omer Mazar, Yossi Yovel
8. 1. Computational and Systems Biology
   2. Neuroscience

   Movement initiation and grasp representation in premotor and primary motor cortex mirror neurons

   Steven Jack Jerjian et al.

   Mirror neurons, including corticospinal neurons, in primary motor cortex of macaque monkeys, clearly dissociate between execution and observation of grasping actions while ventral premotor cortex (F5) maintains a similar representation.
9. 1. Cancer Biology
   2. Computational and Systems Biology

   Dissecting transcriptional amplification by MYC

   Zuqin Nie et al.

   Synthetic biology experiments show that MYC is a general transcription amplifier acting at two or more sites in the transcription-cycle and that MYC-turnover contributes to its activity.
10. 1. Computational and Systems Biology

    Meta-Research: International authorship and collaboration across bioRxiv preprints

    Richard J Abdill et al.

    An analysis of 67,885 preprints on bioRxiv finds evidence for disparities in international participation that are similar to the disparities found in conventional journals.