Computational and Systems Biology

Latest articles

1. 1. Neuroscience
   2. Computational and Systems Biology

   Self-association enhances early attentional selection through automatic prioritization of socially salient signals

   Meike Scheller, Jan Tünnermann ... Jie Sui
2. 1. Computational and Systems Biology
   2. Cancer Biology

   Is tumor mutational burden predictive of response to immunotherapy?

   Carino Gurjao, Dina Tsukrov ... Leonid A Mirny
3. 1. Computational and Systems Biology

   Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis

   Krutik Patel, Matt Barter ... Daryl P Shanley

   A multi-disciplined approach uncovered microRNA-199a/b-5p as important regulators of chondrogenesis, which negatively regulate mRNAs such as FZD6, ITGA3, and CAV1 for protective purposes during chondrogenesis.
4. 1. Computational and Systems Biology

   Ribosome demand links transcriptional bursts to protein expression noise

   Sampriti Pal, Upasana Ray, Riddhiman Dhar
5. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data

   Michael B Hall, Ryan R Wick ... Lachlan Coin

   Nanopore sequencing effectively resolves key challenges in bacterial small variant detection, providing a more accurate alternative to traditional sequencing methods.
6. 1. Computational and Systems Biology

   Point of View: Being a PhD student in Morocco today

   Anas Bedraoui

   Early-career researchers in the Global South have to overcome obstacles that are not found in high-income countries, but in Morocco at least, the future is looking brighter than the past.
7. 1. Computational and Systems Biology
   2. Cancer Biology

   Altered thymic niche synergistically drives the massive proliferation of malignant thymocytes

   Erika Tsingos, Advaita M Dick, Baubak Bajoghli
8. 1. Neuroscience
   2. Computational and Systems Biology

   Dynamic organization of visual cortical networks inferred from massive spiking datasets

   Colin Graber, Yurii Vlasov, Alexander Schwing
9. 1. Cancer Biology
   2. Computational and Systems Biology

   Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data

   Aurélie Anne-Gaëlle Gabriel, Julien Racle ... David Gfeller

   EPIC-ATAC accurately quantifies cell-type heterogeneity in tumor bulk ATAC-Seq samples using reliable cell-type specific chromatin accessibility markers for the major cell types found in tumor microenvironments.
10. 1. Genetics and Genomics
    2. Computational and Systems Biology

    Functional characteristics and computational model of abundant hyperactive loci in the human genome

    Sanjarbek Hudaiberdiev, Ivan Ovcharenko