Computational and Systems Biology

Computational and Systems Biology

eLife publishes research involving the use of methods, models and software. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila

    Luke Stephen Tain et al.
    Multi-omic profiling of gene expression in response to reduced insulin/IGF-like-signalling reveals tissue-specific regulation of DNA damage and lysosomal mannosidase regulation of tissue homeostasis as pro-longevity responses.
    1. Computational and Systems Biology
    2. Neuroscience

    Visuomotor learning from postdictive motor error

    Jana Masselink, Markus Lappe
    Visual, motor, and forward model gains learn from a postdictive update of space to keep perception and saccadic motor function aligned.
    1. Computational and Systems Biology
    2. Ecology

    Nutrient dominance governs the assembly of microbial communities in mixed nutrient environments

    Sylvie Estrela et al.
    There are regularities in how specific nutrients combine together to shape the taxonomic composition of self-assembled communities, with some types of nutrients dominating other types.
    1. Computational and Systems Biology

    Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures

    Martin Jinye Zhang et al.
    Comprehensive single-cell transcriptome analysis reveals global and tissue-specific aging markers and characterizes the heterogeneous aging status of different cell types and tissues in mouse.
    1. Computational and Systems Biology
    2. Neuroscience

    Action detection using a neural network elucidates the genetics of mouse grooming behavior

    Brian Q Geuther et al.
    A machine learning method for action detection is developed and applied toward mouse grooming behavior.

Senior editors

  1. Naama Barkai
    Naama Barkai
    Weizmann Institute of Science, Israel
  2. Aleksandra Walczak
    Ecole Normale Superieure, France
  3. Patricia Wittkopp
    University of Michigan, United States
  4. See more editors