Computational and Systems Biology

Latest articles

1. 1. Computational and Systems Biology

   Barcode-free multiplex plasmid sequencing using Bayesian analysis and nanopore sequencing

   Masaaki Uematsu, Jeremy M Baskin

   SAVEMONEY is a computational tool that guides users to mix plasmids prior to nanopore sequencing, reducing the effective cost of whole-plasmid sequencing to below that of Sanger sequencing.
2. 1. Computational and Systems Biology

   Unsupervised Representation Learning of C. elegans Poses and Behavior Sequences From Microscope Video Recordings

   Maurice Deserno, Katarzyna Bozek
3. 1. Neuroscience
   2. Computational and Systems Biology

   Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging

   Jessica A Haley, Tianyi Chen ... Sreekanth H Chalasani
4. 1. Immunology and Inflammation
   2. Computational and Systems Biology

   Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

   Jan Stuchly, David Novak ... Tomas Kalina
5. 1. Structural Biology and Molecular Biophysics
   2. Computational and Systems Biology

   Atomistic Simulation of Voltage Activation of a Truncated BK Channel

   Zhiguang Jia, Jianhan Chen
6. 1. Computational and Systems Biology
   2. Physics of Living Systems

   Exploiting fluctuations in gene expression to detect causal interactions between genes

   Euan Joly-Smith, Mir Mikdad Talpur ... Andreas Hilfinger
7. 1. Computational and Systems Biology

   SCellBOW: AI-Driven Tumor Risk Stratification from Single-Cell Transcriptomics Using Phenotype Algebra

   Namrata Bhattacharya, Anja Rockstroh ... Debarka Sengupta
8. 1. Neuroscience
   2. Computational and Systems Biology

   Self-Other Generalisation Shapes Social Interaction and Is Disrupted in Borderline Personality Disorder

   Joseph M Barnby, Jen Nguyen ... Peter Fonagy
9. 1. Biochemistry and Chemical Biology
   2. Computational and Systems Biology

   In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins

   Shinichi Kawaguchi, Xin Xu ... Toshie Kai

   AlphaFold2-based large-scale screening reveals novel protein interactions, accelerating functional studies of piRNA pathway proteins and expanding bioinformatic-experimental integration.
10. 1. Computational and Systems Biology
    2. Neuroscience

    Neural population dynamics underlying evidence accumulation in multiple rat brain regions

    Brian DePasquale, Carlos D Brody, Jonathan W Pillow

    A computational framework for combining neural and behavioral data to infer latent dynamics underlying decision-making reveals distinct accumulation dynamics in different brain regions in the rat.