About
Editors and people

Editors for Genetics and Genomics

We aim to review research in areas including the genetic basis of health and disease, comparative and functional genomics, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. We welcome studies in all areas of human genetics as well as those that use cellular and animal models to explore traits of broad relevance to health and disease. We are particularly keen to see studies that use human genetics to drive risk variant discovery, and/or apply such information to provide further mechanistic insights into disease biology, to dissect the genetic architecture of disease, to explore the impact of modifiable risk factors, and/or to support translational advances. Read the latest research in this subject area.

Type

Senior editors

Kathryn Cheah

The University of Hong Kong, Hong Kong SAR China

Kathryn Cheah is a developmental geneticist and Jimmy & Emily Tang Professor in Molecular Genetics and Chair Professor of Biochemistry at the University of Hong Kong. She received her BSc Hons degree in Biology from the University of London and PhD in Molecular Biology from Cambridge University, U.K. After postdoctoral training at the University of Manchester and Imperial Cancer Research Fund in the UK, she joined the University of Hong Kong. Her research focuses on using functional genomics and mouse models to understand gene function and regulation, the associated gene regulatory networks and mechanisms of disease, with a focus on skeletal and inner ear development, congenital and common skeletal disorders. Notable contributions are the identification of SOX2 as essential for prosensory development in the inner ear, SOX9 as a key regulator of COL2A1 and the cartilage gene regulatory network, a lineage continuum for cartilage and bone cells and a causative mechanistic link between endoplasmic reticulum stress and skeletal disorders. She is an elected Fellow of the Global Science Academy, The World Academy Sciences (TWAS).

She was the founding President of the Hong Kong Society for Developmental Biology and the Hong Kong representative for the Asia-Pacific Developmental Biology Network and the International Society of Developmental Biology (2004-2013), elected President of the International Society for Matrix Biology (2006-2008), Senior External Fellow of the University of Freiburg Institute of Advanced Studies (2011-2012) and elected member of the Board of Directors of the International Society of Differentiation (2012-2018).

She brings editorial expertise to eLife having previously served as Associate Editor for Genesis, guest Associate Editor for PLOS Genetics, Asian Editor for Development Growth & Differentiation (2015-2016), editorial board member of Matrix Biology, BioEssays, Annual Reviews of Genomics & Human Genetics, and as Reviewing Editor of eLife.

Expertise
Developmental Biology
Genetics and Genomics

Research focus
gene regulation and development
inherited and degenerative skeletal disorder
inner ear
matrix biology

Experimental organism
mouse
human

Competing interests statement
Kathryn Cheah receives research funding from the Hong Kong Research Grants Council and the Hong Kong Health and Medical Research Fund. She is serving as a member of Hong Kong’s University Grants Council Biology Panel for the Research Assessment Exercise 2020. She currently also serves on the editorial boards of Scientific Reports, Genesis and Journal of Orthopaedic Research. She is also serving on the Hong Kong Advisory Board of the Gordon Research Conferences (GRC) and the GRC Conference Evaluation Committee.
Murim Choi

Seoul National University College of Medicine, South Korea

Murim Choi’s main scientific question is to elucidate the genetic mechanisms of human diseases. To address this, his expertise lies in the functional interpretation of human genetic variants using genomic and bioinformatic methodologies. He graduated from Seoul National University (SNU), Seoul, Korea, majoring in Molecular Biology (BS and MS). During the Ph.D course at Duke University, he studied cardiovascular system development in mice. In his postdoctoral training at Yale University, he studied human genetics, setting up a whole exome sequencing pipeline and applying it to various human diseases to identify causal genes. He received a K99/R00 grant for the postdoctoral works and was a recipient of SNU Invitation Program for Distinguished Scholar grant.

Establishing his independent lab at SNU, he has been studying the genetic mechanisms of rare disease pathogenesis, focusing on cases with neurodevelopmental defects. His current approach combines developmental biology and genetics, shaped by the fact that most pediatric rare disease patients experience congenital problems. More recently, his group has undertaken common disease research. His group recently established a bioinformatic pipeline that allows screening of eQTL signals only functioning in the non-alcoholic fatty liver disease (NAFLD) status and validated its utility. At SNU, he has been instrumental in establishing genetics and genomics methodologies by collaborating with clinicians in SNU Hospital. His lab has recently established protocols in advanced functional genomics approaches, including single-cell sequencing, saturation mutagenesis, modifier screening, and cell tracing technique to understand the genetic mechanisms underlying disease progression.

He has a strong interest in clinical and translational research, especially in elucidating genotype-phenotype relationships that may lead to human diseases. In 2018, he was selected as a member of the Young Korean Academy of Science and Technology.

Expertise
Genetics and Genomics
Medicine

Research focus
rare diseases
neurodevelopmental disorders
functional characterization of genetic variants
bioinformatics
Mendelian genetics

Competing interests statement
Current funding: Genetic elucidation of rare developmental disorders (200M KRW/year (~152,800 USD); Apr. 2014-Sep.2022; National Research Foundation of Ministry of Science and ICT); Genetic elucidation of gene expression noises (300M KRW/year (~229,200 USD); Mar. 2021-Feb. 2025; National Research Foundation of Ministry of Science and ICT); Discovery of NAFLD causing genes using single cell expression quantitative trait loci approach (80M KRW/year (~61,120 USD); Apr. 2021-Dec. 2025; National Research Foundation of Ministry of Science and ICT).Other editorial roles: editor of Experimental and Molecular Medicine (Springer Nature)
Yamini Dalal

National Cancer Institute, United States

Yamini Dalal did her graduate work on chromatin structure with Arnie Stein and Minou Bina at Purdue University (PhD, 2003), and her postdoctoral research on centromeres with Steve Henikoff at the Fred Hutch Cancer Research Center (2007). She is currently a Senior Investigator leading the Chromosome Structure and Epigenetics Mechanism Unit within the Laboratory of Receptor Biology and Gene Expression at the Center for Cancer Research of the NCI/NIH in Bethesda. Her lab focuses on histones, which package the entirety of the human genome into chromatin. Using a combination of chromatin biochemistry, computational modelling, atomic force microscopy (AFM), genetics, genomics and cell biology, Dr. Dalal and colleagues are investigating whether chromatin adopts alternate structural conformations in cancer cells, the functional consequences of large-scale chromosomal alterations upon the cancer epigenome, and identifying small molecules which can target these structures or processes.

Expertise
Cancer Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromatin
centromeres
chromosomes
mitosis
chromosome cancer biology
histone variants
nucleosomes
histones

Experimental organism
human
mouse

Competing interests statement
Dr. Dalal is serving as Deputy Editor of eLife in her personal capacity as a chromosome biology expert with a deep interest in molecular and cellular biology, not as a representative of the NIH.
Adèle L Marston

University of Edinburgh, United Kingdom

Adèle Marston is Professor of Cell Biology at the University of Edinburgh, a Wellcome Investigator and Director of the Wellcome Discovery Research Platform for Hidden Cell Biology. Adèle investigates the fundamental mechanisms by which cells reproduce themselves and transmit their genome to the next generation. She has a particular interest in meiosis, the cell division that generates eggs and sperm. Her laboratory takes a multi-disciplinary approach to identify the fundamental mechanisms of chromosome segregation in model organisms, including yeast, frogs and mice. To understand the relevance of these discoveries for human fertility, she also works with clinicians to investigate the origins of chromosome segregation errors in human oocytes.

Expertise
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromosome biology
cell biology
reproductive biology
meiosis
mitosis
chromosome segregation
cell cycle

Experimental organism
S. cerevisiae
S. pombe
xenopus laevis
mouse
human

Competing interests statement
Adèle Marston is funded by Wellcome. She has served as Reviewing Editor for eLife.
Alan Moses

University of Toronto, Canada

Alan M Moses is currently Professor and Canada Research Chair in Computational Biology in the Departments of Cell & Systems Biology and Computer Science at the University of Toronto. His research touches on many of the major areas in computational biology, including DNA and protein sequence analysis, phylogenetic models, population genetics, expression profiles, regulatory network simulations and image analysis. Recent areas of focus include machine learning applied to microscope images, protein and genome sequences, to better understand subcellular localization, intrinsically disordered regions and regulatory sequences in non-coding DNA.

Expertise
Computational and Systems Biology
Evolutionary Biology
Genetics and Genomics

Research focus
data analysis
bioinformatics
molecular evolution
intrinsically disordered proteins
signaling pathways
regulatory networks

Experimental organism
S. cerevisiae

Competing interests statement
- Current research funding: Canadian Institutes of Health Research (CIHR), National Science and Engineering Research Council (NSERC), Canada Research Chairs (CRC)- Other editorial roles: Associate Editor, Genetics
Sacha B Nelson

Brandeis University, United States

Sacha Nelson is the Tauber Professor of Biology and Chair of the Program in Neuroscience at Brandeis University in Waltham, Massachusetts. He received his MDPhD (Biology) from UCSD in 1991, did postdoctoral work at MIT and has been at Brandeis University since 1994. He has received awards from the Sloan, McKnight and Rett Syndrome Research Foundations. His current research focuses on transcriptional networks underlying neuronal plasticity and excitability in the mammalian neocortex.

Expertise
Neuroscience
Genetics and Genomics

Research focus
regulation of neuronal gene expression
cellular and systems electrophysiology
developmental disorders
learning and synaptic plasticity

Experimental organism
mouse

Competing interests statement
Sacha Nelson receives funding from the NIH and from the WM Keck Foundation. He serves on the Advisory Boards for eNeuro and for the Carney Institute for Brain Science at Brown University.
Dominique Soldati-Favre

University of Geneva, Switzerland

Dr Dominique Soldati-Favre studied biochemistry and earned her PhD degree in molecular biology from the University of Zürich (Switzerland). She is full Professor at the department of Microbiology and Molecular Medicine at the Faculty of Medicine of the University of Geneva. Her laboratory is studying obligate intracellular parasitism using Toxoplasma gondii. The main line of research focuses on the cell biology underlying parasite active invasion into mammalian cells. Her group is also aiming at defining the metabolic needs and capabilities of the parasites as well as how they subvert host cellular functions notably to access nutrients.

Expertise
Microbiology and Infectious Disease
Biochemistry and Chemical Biology
Cell Biology
Genetics and Genomics

Research focus
parasitology
organelle biogenesis
protein trafficking
metabolism
host pathogen interaction
signalling

Experimental organism
T. gondii
apicomplexans
kinetoplastids

Competing interests statement
Dominique Soldati-Favre’s research is currently funded by the Swiss National Science Foundation. She serves as Section Editor at PLOS Pathogens, and Editor at mBio.
Detlef Weigel

Max Planck Institute for Developmental Biology, Germany

Detlef Weigel received his PhD in 1988 from the Max Planck Institute for Developmental Biology. After postdoctoral work at the California Institute of Technology, he joined the faculty of the Salk Institute in 1993. Since 2002, he has been director of the Department of Molecular Biology at the Max Planck Institute for Developmental Biology. His current research interests focus on natural genetic variation and evolutionary genomics of plants. Examples of recent important projects are the 1001 Genomes project for Arabidopsis thaliana, and the systematic dissection of deleterious epistasis between Arabidopsis strains due to autoimmunity. Among the awards he has received are the Young Investigator Award of the National Science Foundation, the Gottfried Wilhelm Leibniz Award of the Deutsche Forschungsgemeinschaft, and the Otto Bayer Award. He is a member of the US National Academy of Sciences, the German National Academy of Sciences Leopoldina and the Royal Society.

Expertise
Plant Biology
Genetics and Genomics
Evolutionary Biology

Research focus
plants
genomics
evolution
genetic variation
evolutionary genomics
adaptation
microbiome

Experimental organism
A. thaliana

Competing interests statement
Detlef Weigel has received funding from the Max Planck Society, the Deutsche Forschungsgemeinschaft, the Foundation of the State of Baden-Württemberg, the German Ministry for Education and Research, the European Commission, the Human Frontiers Science Program Organization, and several US Federal agencies. He serves on the Editorial Boards of Annual Review of Cell and Developmental Biology and Genome Biology. He is Chair of EMBO Council, and is serving or has recently served on the Advisory Boards of the Epigenomics of Plants International Consortium, Bayer Crop Science, The Arabidopsis Information Resource, Flanders Institute of Biotechnology, Temasek Life Sciences Laboratory, and the Sainsbury Laboratory. He is a co-founder of Computomics and CeMet.
Wei Yan

Washington State University, United States

Wei Yan obtained his MD from China Medical University and PhD from University of Turku, Finland. After finishing his post-doc training at Baylor College of Medicine, Houston, TX, he started his own lab at the University of Nevada School of Medicine, where he rose through the ranks and eventually named University Foundation Professor, the highest honor the University bestows upon its faculty. In 2020, he joined The Lundquist Institute at Harbor-UCLA to direct the newly established National Center for Male Reproductive Epigenomics, one of the seven National Centers for Translational Research in Reproduction and Infertility (NCTRI) supported by the NICDH. The Yan lab works on genetic and epigenetic control of fertility and the epigenetic contribution of gametes to fertilization, early embryonic development, and adulthood health. He has so far published over 160 peer-reviewed research articles and book chapters with over 12,00 citations.

His lab first put forward a novel idea for the development of non-hormonal male contraceptives: “Do not kill, but disable sperm”, which led to the discovery of TRIPTONIDE, a natural compound, as a reversible non-hormonal contraceptive agent in mice and monkeys, and established it as a drug candidate for “The Pill” for men. His lab also discovered the function of motile cilia in the reproductive tracts. In the male, motile ciliary beating function as an agitator to maintain the constant suspension of immotile testicular sperm during their transit through the efferent ductules in men. In the female, motile cilia in the oviduct/Fallopian tube are essential for oocyte pickup and fertility, but dispensable for embryo and sperm transport, which are mostly achieved through smooth muscle contraction. This discovery solved the long-standing controversy about the role of cilia beating vs. muscle contraction in gamete/embryo transport. His lab elucidated several novel mechanisms underlying the unique regulation of gene expression during the haploid phase of spermatogenesis, including global shortening of transcripts, delayed translation/uncoupling of transcription and translation, and dynamic changes in poly(A) length and non-A contents. His lab first discovered mitochondrial genome-encoded small RNAs (mitosRNAs), endo-siRNAs in the male germline and MSCI-escaping X-linked miRNAs. His lab was also among those that suggested critical functions of sperm-borne RNAs in supporting early embryonic development and epigenetic inheritance.

Wei Yan’s contributions to science have been recognized by several academic awards, including the 2009 Society for the Study of Reproduction (SSR) Young Investigator Award, the 2012 American Society of Andrology (ASA) Young Andrologist Award, the 2013 Nevada Healthcare Hero Award for Research and Technology, the 2017 University of Nevada, Reno Outstanding Researcher Award, the 2018 SSR Research Award and the 2020 Nevada System of Higher Education Research Award. Dr Yan was elected Fellow of the American Association for the Advancement of Science (AAAS) in 2017 and SSR Distinguished Fellow in 2023.

Expertise
Developmental Biology
Genetics and Genomics
Medicine

Research focus
reproduction
epigenetic inheritance
regulation of spermatogenesis
female infertility
sperm biology
reproductive tract
ovarian biology
female fertility
contraceptive development
endocrine control of reproduction and fertility
germline epigenetic reprogramming
sperm-borne large and small RNA

Competing interests statement
The Yan lab receives funding from the NIH, Male Contraceptive Initiative, and John Templeton Foundation. Wei Yan serves on the Advisory Board of Contraceptive Accelerator Network, LLC. Wei Yan served as co-Editor-in-Chief of Biology of Reproduction (2017-2021). He serves as Associate Editor for Environmental Epigenetics and Reviewing Editor for FASEB journal.

Reviewing editors

Musa Ali

Hawassa University, Ethiopia

Expertise
Epidemiology and Global Health
Genetics and Genomics
Immunology and Inflammation
Microbiology and Infectious Disease

Research focus
infectious diseases
antimicrobial resistance
molecular epidemiology
hospital-acquired infection
Bhat Altaf

University of Kashmir, India

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromatin
heterochromatin
transcription
histone modifications
genome organisation
RNA-binding proteins
chromatin in DNA repair
epigenetics
autophagy

Experimental organism
human
budding yeast
fission yeast
Nicolas Altemose

Stanford University, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Computational and Systems Biology

Research focus
chromatin
centromeres
heterochromatin
epigenomics
microfluidics
meiotic recombination
Long-read sequencing
Repetitive DNA

Experimental organism
human
mouse
Richard Amasino

University of Wisconsin-Madison, United States

Expertise
Plant Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
plant development and epigenetics

Experimental organism
A. thaliana
B. distachyon
Joon-Yong An

Korea University, South Korea

Expertise
Medicine
Computational and Systems Biology
Genetics and Genomics
Neuroscience

Research focus
whole genome sequencing
noncoding mutation
neurodevelopment
autism spectrum disorders
multi-omics
Aseem Z Ansari

St. Jude Children's Research Hospital, United States

Expertise
Chromosomes and Gene Expression
Biochemistry and Chemical Biology
Genetics and Genomics

Research focus
gene expression
chemical biology
synthetic biology
transcription factors
molecular recognition
synthetic gene regulators
transcription therapy
RNA polymerase II regulation
transcriptional kinases
DNA binding specificity
Caetano Antunes

University of Kansas, United States

Expertise
Biochemistry and Chemical Biology
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
microbiome
host-microbe interactions
metabolomics
gene regulation
microbial signaling
Daniel Arango

Northwestern University, United States

Expertise
Biochemistry and Chemical Biology
Genetics and Genomics

Research focus
RNA modifications
mRNA processing
mRNA translation
mRNA stability
H. Efsun Arda

National Cancer Institute, United States

Expertise
Developmental Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
pancreas
single-cell
enhancers
chromatin
Kavita Babu

Indian Institute of Science Bangalore, India

Expertise
Genetics and Genomics
Neuroscience

Research focus
synapse
neuropeptides
worm behavior
cell adhesion molecules

Experimental organism
C. elegans
Hua Bai

Iowa State University, United States

Expertise
Cell Biology
Developmental Biology
Genetics and Genomics

Research focus
human cell culture

Experimental organism
Drosophila
Rebecca Bart

The Donald Danforth Plant Science Center, United States

Expertise
Plant Biology
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
host-pathogen-environment interactions
non-model organisms
cassava
Xanthomonas
genetics
genomics
Esteban J Beckwith

Universidad de Buenos Aires - CONICET, Argentina

Expertise
Genetics and Genomics
Immunology and Inflammation
Neuroscience

Research focus
circadian
sleep
learning
memory
innate immunity
bacterial infections
insect behaviour

Experimental organism
drosophila
Hugo J Bellen

Baylor College of Medicine, United States

Expertise
Neuroscience
Developmental Biology
Genetics and Genomics

Research focus
neurobiology
human neurological disease
Alzheimer's disease
Parkinson's disease
diagnosis of human genetic diseases
fly technology
CRIMIC
MiMIC

Experimental organism
D. melanogaster
mouse
Daniel W Belsky

Columbia University, United States

Expertise
Epidemiology and Global Health
Genetics and Genomics

Research focus
aging
epidemiology
lifecourse
Bérénice A Benayoun

University of Southern California, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Immunology and Inflammation

Research focus
aging
macrophages
inflammation
sex differences
menopause
sex hormones

Experimental organism
mouse
African turquoise killifish
Benjamin K Blackman

University of California, Berkeley, United States

Expertise
Evolutionary Biology
Genetics and Genomics
Plant Biology

Research focus
evolutionary genetics
evolution of development
phenotypic variation
domestication
local adaptation
plant reproduction
Philip Boonstra

University of Michigan, United States

Expertise
Medicine
Epidemiology and Global Health
Cancer Biology
Genetics and Genomics

Research focus
biostatistics
clinical trials
cancer biostatistics
epidemiology
ECMO
statistical programming
Sigurd J Braun

Justus-Liebig University Giessen, Germany

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromatin
epigenetics
gene silencing
genome stability
ubiquitin
histone modifications
phenotypic screens

Experimental organism
fission yeast
budding yeast
Gertraud Burger

University of Montreal, Canada

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Microbiology and Infectious Disease
Plant Biology

Research focus
genomics
transcriptomics
proteomics
bioinformatics
microeukaryotes
microbe-plant interactions
eukaryotic evolution
Shai Carmi

The Hebrew University of Jerusalem, Israel

Expertise
Genetics and Genomics
Evolutionary Biology
Epidemiology and Global Health

Research focus
ancient DNA
polygenic scores
human population genetics
genetic genealogy
coalescent theory
demographic inference
preimplantation genetic testing
forensic DNA
Vincent Castric

Université de Lille, France

Expertise
Evolutionary Biology
Genetics and Genomics
Plant Biology

Research focus
evolutionary genomics
population genetics
small regulatory RNAs
mating systems
transposable elements
gene regulatory networks
self-incompatibility
receptor-ligand interaction

Experimental organism
Arabidopsis
Frank Chan

Groningen Institute for Evolutionary Life Sciences, University of Groningen, Netherlands

Expertise
Developmental Biology
Evolutionary Biology
Genetics and Genomics

Research focus
evolution
adaptation
complex traits
transcriptional regulation
non-model organisms
selective sweeps
single-cell techniques
haplotypes
genomes
genetic mapping

Experimental organism
mouse
Sara Cherry

University of Pennsylvania, United States

Expertise
Genetics and Genomics
Immunology and Inflammation
Microbiology and Infectious Disease

Research focus
virology
microbiology
innate immunity
genetics
genomics
emerging pathogens

Experimental organism
D. melanogaster
Irene E Chiolo

University of Southern California, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
DNA repair
double strand break repair
DNA recombination
chromosome dynamics
nuclear architecture
nuclear dynamics
nuclear actin filaments

Experimental organism
D. melanogaster
mouse
Jungmin Choi

Korea University College of Medicine, South Korea

Expertise
Cancer Biology
Computational and Systems Biology
Genetics and Genomics
Medicine

Research focus
rare disorders
single cell genomics
computational biology
human genomics
Julia P Cooper

University of Colorado Anschutz Medical Campus, United States

Expertise
Chromosomes and Gene Expression
Cell Biology
Genetics and Genomics

Research focus
telomeres
centromeres
genome stability
Virginie Courtier-Orgogozo

Université Paris-Diderot CNRS, France

Expertise
Evolutionary Biology
Genetics and Genomics

Research focus
genotype-phenotype
evolutionary genetics
morphological evolution
physiological evolution
gene drive

Experimental organism
D. melanogaster
Jose Renato Rosa Cussiol

Federal University of São Paulo, Brazil

Expertise
Biochemistry and Chemical Biology
Cell Biology
Cancer Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
DNA damage response
yeast genetics
DNA damage signaling
genomic instability
inositol metabolism
inositol polyphosphate pathway
Weiwei Dang

Baylor College of Medicine, United States

Expertise
Cell Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
aging
epigenetics
histone modifications
chromatin
chromatin remodeling
yeast
yeast aging
stem cell aging

Experimental organism
S. cerevisiae
C. elegans
mouse
human
Jeremy Day

University of Alabama at Birmingham, United States

Expertise
Neuroscience
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
CRISPR/Cas
gene regulation
genomic enhancers
long non-coding RNAs
drug addiction
dopamine
reward
motivated behavior

Experimental organism
rat
mouse
cell cultures
Joris Deelen

Leiden University Medical Center, Netherlands

Expertise
Epidemiology and Global Health
Genetics and Genomics

Research focus
aging
longevity
age-related diseases
genetics
functional characterization of genetic variants
CRISPR/Cas9
biomarkers of aging
biology of aging

Experimental organism
mouse
human
Filippo Del Bene

Institut de la Vision, France

Expertise
Developmental Biology
Neuroscience
Genetics and Genomics

Research focus
zebrafish
visual system
optogenetics
neural circuits
behavior
brain function
genome editing
Martin S Denzel

Altos Labs, Cambridge Institute of Science, United Kingdom

Expertise
Biochemistry and Chemical Biology
Genetics and Genomics

Research focus
aging
metabolism
protein homeostasis
cell culture

Experimental organism
C. elegans
mouse
H Melike Dönertaş

Leibniz Institute on Aging - Fritz Lipmann Institute, Germany

Expertise
Computational and Systems Biology
Genetics and Genomics

Research focus
aging
multi-omics
microbiome
computational drug repurposing
human cohort analysis
Xin Duan

University of California, San Francisco, United States

Expertise
Developmental Biology
Genetics and Genomics
Neuroscience

Research focus
synapse formation
superior colliculus
optic neuropathy
retinal circuitry
transsynaptic tracing
cadherins
optic nerve regeneration
Eugene P Duff

Imperial College London, United States

Expertise
Genetics and Genomics
Neuroscience
Chromosomes and Gene Expression

Research focus
proteomics
dementia
functional neuroimaging
functional connectivity
single cell RNA sequencing
gene expression networks
multimorbidity
Dieter Ebert

University of Basel, Switzerland

Expertise
Evolutionary Biology
Genetics and Genomics

Research focus
coevolution
experimental evolution
host-parasite interactions
population genetics
balancing selection
evolution
biogeography

Experimental organism
Daphnia
Hannelore Ehrenreich

Max Planck Institute of Experimental Medicine, Germany

Expertise
Genetics and Genomics
Immunology and Inflammation
Medicine
Neuroscience

Research focus
translational neuroscience
erythropoietin
hypoxia
neuropsychiatric phenotypes
deep phenotyping
autoantibodies

Experimental organism
human
Eran Elhaik

Lund University, Sweden

Expertise
Evolutionary Biology
Genetics and Genomics

Research focus
bioinformatics
biogeography
population genomics
population genetics
molecular evolution
paleogenetics
forensics
David Enard

University of Arizona, United States

Expertise
Evolutionary Biology
Genetics and Genomics

Research focus
population genomics
natural selection
molecular evolution
genomic adaptation
host-virus interactions
host adaptation to pathogens
ecological genomics of adaptation
John Ewer

Universidad de Valparaiso, Chile

Expertise
Developmental Biology
Neuroscience
Genetics and Genomics
Medicine

Research focus
animal behaviour
neuropeptides
circadian clocks
insect endocrinology

Experimental organism
D. melanogaster
Paula Fernandez

INTA, Argentina

Expertise
Genetics and Genomics
Plant Biology

Research focus
genomics
system biology
ecophysiology
leaf senescence
transcriptomics
metabolomics
phenomics
Jonathan Flint

University of California, Los Angeles, United States

Expertise
Genetics and Genomics
Medicine

Research focus
genetics
genomics
psychiatric disorders
Yvonne Fondufe-Mittendorf

Van Andel Institute, United States

Expertise
Genetics and Genomics
Chromosomes and Gene Expression
Cancer Biology

Research focus
gene expression
chromatin biology
toxicology
RNA biology
nucleosome structure
Alexandre Fournier-Level

The University of Melbourne, Australia

Expertise
Genetics and Genomics
Plant Biology
Evolutionary Biology

Research focus
natural variation
quantitative genetics
population genetics
invasion
weeds
genomic prediction
Ziyue Gao

University of Pennsylvania, United States

Expertise
Evolutionary Biology
Genetics and Genomics
Chromosomes and Gene Expression

Research focus
population genetics
human genetics
mutation rate
natural selection
genetic variation
ancient DNA

Experimental organism
human
non-human primates
Gregory G Germino

National Institute of Diabetes and Digestive and Kidney Diseases, United States

Expertise
Medicine
Genetics and Genomics

Research focus
nephrology
genetic renal disease
internal medicine
ciliopathies

Experimental organism
mouse
rat
human
Arjumand Ghazi

University of Pittsburgh School of Medicine, United States

Expertise
Developmental Biology
Genetics and Genomics
Immunology and Inflammation
Stem Cells and Regenerative Medicine

Research focus
aging
geroscience
reproductive aging
longevity
healthspan
oocytes
innate immunity
inflammation
proteostasis

Experimental organism
C. elegans
Drosophila melanogaster
mouse
Evangelos J Giamarellos-Bourboulis

Attikon University Hospital, Greece

Expertise
Immunology and Inflammation
Microbiology and Infectious Disease
Genetics and Genomics
Medicine

Research focus
sepsis
hidradenitis suppurativa
pathogenesis of infection
biomarkers
Thomas Gingeras

Cold Spring Harbor Laboratory, United States

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
genomics
gene expression
regulatory networks
chromosomal modification

Experimental organism
D. melanogaster
human
mouse
David Ginsburg

University of Michigan, United States

Expertise
Medicine
Genetics and Genomics

Research focus
hemostasis
thrombosis
protein secretion
human genetics
fibrinolysis

Experimental organism
human
mouse
zebrafish
Simona Giunta

Sapienza University of Rome, Italy

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
centromeres
Repetitive DNA
chromatin
DNA damage
DNA damage response
mutagenesis
epigenomics
DNA damage repair
Rosalyn Gloag

University of Sidney, Australia

Expertise
Evolutionary Biology
Genetics and Genomics
Ecology

Research focus
invasive species
population genetics
brood parasitism
social parasitism
eusociality

Experimental organism
birds
bees
Gustavo H Goldman

Universidade de Sao Paulo, Brazil

Expertise
Biochemistry and Chemical Biology
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
filamentous fungi
Aspergillus
secondary metabolites
gene expression
molecular biology
infectious diseases
drug tolerance
Alla Grishok

Boston University, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
small RNAs
epigenetics
DOT1L
H3K79
argonaute

Experimental organism
C. elegans
Iqbal Hamza

University of Maryland, United States

Expertise
Biochemistry and Chemical Biology
Cell Biology
Genetics and Genomics

Research focus
metals
anemia
iron
heme

Experimental organism
mouse
C. elegans
parasites
Gaiti Hasan

Tata Institute of Fundamental Research, National Centre for Biological Sciences, India

Expertise
Genetics and Genomics
Neuroscience
Medicine

Research focus
calcium signaling
motor function
regulation of gene expression
IP3R
STIM
Orai

Experimental organism
D. melanogaster
P Robin Hiesinger

Institute for Biology Free University Berlin, Germany

Expertise
Cell Biology
Computational and Systems Biology
Developmental Biology
Genetics and Genomics
Neuroscience

Research focus
brain development
synapse
neurogenetics
membrane trafficking
Drosophila
neurodegeneration
computational modelling
live-cell imaging

Experimental organism
D. melanogaster
organoids
Patrick J Hu

Vanderbilt University School of Medicine, United States

Expertise
Medicine
Developmental Biology
Genetics and Genomics

Research focus
signal transduction
genetics
development
aging
cancer
endoplasmic reticulum homeostasis
dauer

Experimental organism
C. elegans
Emilia Huerta-Sanchez

Brown University, United States

Expertise
Ecology
Evolutionary Biology
Genetics and Genomics

Research focus
natural selection
population demography
Gaspar Jekely

University of Exeter, United Kingdom

Expertise
Genetics and Genomics
Neuroscience
Evolutionary Biology

Research focus
nervous system evolution
marine larvae
cilia
sensory systems
eukaryogenesis
neuromodulation

Experimental organism
P. dumerilii
C. hemisphaerica
N. vectensis
Trichoplax
Koichi Kawakami

National Institute of Genetics, Japan

Expertise
Developmental Biology
Genetics and Genomics
Neuroscience

Research focus
organogenesis
disease models
biotechnology
optogenetics
transposable elements
behavior
brain function
neural circuits

Experimental organism
zebrafish
Megan C King

Yale School of Medicine, United States

Expertise
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Physics of Living Systems

Research focus
nuclear envelope
nuclear lamins
LINC complex
nuclear mechanics
DNA repair
genome organisation

Experimental organism
mouse
Genevieve Konopka

The University of Texas Southwestern Medical Center, United States

Expertise
Neuroscience
Genetics and Genomics
Evolutionary Biology

Research focus
comparative genomics
autism
schizophrenia
neurogenomics
cognition
language
molecular neuroscience

Experimental organism
human
mouse
Paschalis Kratsios

University of Chicago, United States

Expertise
Developmental Biology
Genetics and Genomics
Neuroscience

Research focus
neuronal development
transcription factors
chromatin factors
neuronal identity
genetics

Experimental organism
C. elegans
mouse
Shigehiro Kuraku

National Institute of Genetics, Japan

Expertise
Evolutionary Biology
Genetics and Genomics
Developmental Biology

Research focus
molecular evolution
gene family evolution
developmental roles of duplicated genes
early vertebrate genome evolution

Experimental organism
reptiles
cyclostomes
chondrichthyans
Ashish Lal

National Institutes of Health, United States

Expertise
Cancer Biology
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
RNA biology
lncRNAs
microRNAs
gene regulation
cancer biology
p53

Experimental organism
human
Dan Larhammar

Uppsala University, Sweden

Expertise
Medicine
Evolutionary Biology
Neuroscience
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
evolution
gene/genome duplications
cellular and molecular neuroscience
G protein-coupled receptors (GPCR)
neuropeptides
endocrine peptides
phototransduction
ligand-gated ion channels

Experimental organism
human
zebrafish
Katherine Lawler

University of Cambridge, United Kingdom

Expertise
Computational and Systems Biology
Genetics and Genomics

Research focus
DNA sequencing
RNA sequencing
metabolomics
Sihoon Lee

Gachon University College of Medicine, South Korea

Expertise
Medicine
Genetics and Genomics

Research focus
endocrinology
hormones
parathyroid
bone metabolism
rare diseases
thyroid hormone metabolism
deiodinase
insulin resistance
Sylvia Lee

Cornell University, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
aging

Experimental organism
C. elegans
Scott F Leiser

University of Michigan, United States

Expertise
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Neuroscience

Research focus
aging
longevity
hypoxia
geroscience
proteostasis
stress response
flavin-containing monooxygenase
healthspan
Falong Lu

Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China

Expertise
Developmental Biology
Genetics and Genomics
Stem Cells and Regenerative Medicine
Chromosomes and Gene Expression

Research focus
epigenetics
RNA modifications
imprinting
stem cells
reprogramming
poly(A) tail
early embryo
chromatin modifications

Experimental organism
mouse
human
Vincent J Lynch

University at Buffalo, State University of New York, United States

Expertise
Chromosomes and Gene Expression
Evolutionary Biology
Genetics and Genomics

Research focus
evolutionary medicine
evolutionary cell biology
cancer
gene regulation
developmental evolution (DevoEvo)
pregnancy
Arya Mani

Yale University School of Medicine, United States

Expertise
Medicine
Genetics and Genomics

Research focus
lipid metabolism
glucose metabolism
fatty liver disease
hyperlipidemia
cardiovascular genetics

Experimental organism
mouse
Salem Y Mohamed

Zagazig University, Egypt

Expertise
Cancer Biology
Cell Biology
Chromosomes and Gene Expression
Epidemiology and Global Health
Genetics and Genomics
Immunology and Inflammation
Medicine
Microbiology and Infectious Disease

Research focus
advanced endoscopy
cell biology
cancer
inflammation
genetics
basic medicine
Subburaman Mohan

Loma Linda University, United States

Expertise
Medicine
Genetics and Genomics

Research focus
bone biology
endochondral bone formation
insulin-like growth factors
osteoporosis
osteoarthritis
skeletal development

Experimental organism
human
Marcelo A Mori

State University of Campinas, Brazil

Expertise
Biochemistry and Chemical Biology
Cell Biology
Chromosomes and Gene Expression
Genetics and Genomics
Immunology and Inflammation

Research focus
aging
metabolism
obesity
adipose tissue
microRNAs
endocrinology
integrative physiology
Marcos Nahmad

Centre for Research and Advanced Studies, Mexico

Expertise
Computational and Systems Biology
Developmental Biology
Genetics and Genomics
Physics of Living Systems

Research focus
growth control
drosophila genetics
developmental patterning
mathematical modelling
Goutham Narla

University of Michigan, United States

Expertise
Medicine
Cancer Biology
Genetics and Genomics

Research focus
cancer therapeutics
cancer genetics
small molecule drug development
protein phosphatase

Experimental organism
human
mouse
Marisa Nicolás

Laboratório Nacional de Computação Científica, Brazil

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
molecular biology
bioinformatics
genomics
transcriptomics
multi-omics approaches
clinical pathogens
antimicrobial resistance
metabolic regulatory networks
transcriptional regulatory networks
Ellen AA Nollen

University of Groningen, Netherlands

Expertise
Cell Biology
Genetics and Genomics

Research focus
Parkinson's disease
neurodegeneration
Dimple Notani

National Centre for Biological Sciences, India

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
genomics
single cell perturbations
molecular biology
microscopy
Izuchukwu Okafor

Nnamdi Azikiwe University, Nigeria

Expertise
Cancer Biology
Cell Biology
Chromosomes and Gene Expression
Developmental Biology
Epidemiology and Global Health
Genetics and Genomics
Medicine
Neuroscience

Research focus
developmental biology
reproductive biology
gene expression
molecular biology
public health
reproductive health
medical education
anatomical sciences
neuroreproduction
Stephen Parker

University of Michigan, United States

Expertise
Genetics and Genomics
Chromosomes and Gene Expression
Computational and Systems Biology

Research focus
diabetes
disease susceptibility
functional genomics
comparative genomics
population genomics

Experimental organism
human
mouse
rat
David A Paz-Garcia

Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Mexico

Expertise
Chromosomes and Gene Expression
Computational and Systems Biology
Ecology
Evolutionary Biology
Genetics and Genomics
Microbiology and Infectious Disease
Plant Biology

Research focus
marine life
coral reefs
phylogenomics
population genomics
morphometrics
gene expression
statistics
coding
Marianoel Pereira-Gómez

Institut Pasteur de Montevideo, Uruguay

Expertise
Evolutionary Biology
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
viruses
evolution
genetics
mutation rate
mutagenesis
experimental evolution
virology
molecular biology
Luca Pinello

Massachusetts General Hospital, United States

Expertise
Medicine
Computational and Systems Biology
Genetics and Genomics

Research focus
bioinformatics
computational biology
CRISPR genome editing
single-cell genomics
Wenfeng Qian

Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China

Expertise
Evolutionary Biology
Genetics and Genomics

Research focus
codon usage
yeast genomics
mutational spectrum
fitness landscape
gene duplication
translational regulation
Mani Ramaswami

Trinity College, Dublin, Ireland

Expertise
Cell Biology
Genetics and Genomics
Neuroscience

Research focus
RNA granules
RNA binding proteins
neuronal translational control
ALS models
inhibitory plasticity and memory
behavioral circuits
habituation
modulation of behaviour

Experimental organism
D. melanogaster
Jalees Rehman

University of Illinois at Chicago, United States

Expertise
Cell Biology
Genetics and Genomics
Immunology and Inflammation
Medicine
Stem Cells and Regenerative Medicine

Research focus
vascular biology
macrophage biology
inflammation
transcriptomics
single cell analysis
lung biology
cell regeneration
Tania Reis

University of Colorado Anschutz Medical Campus, United States

Expertise
Genetics and Genomics
Chromosomes and Gene Expression
Neuroscience

Research focus
obesity
energy homeostasis
RNA binding proteins
sex differences
alternative splicing

Experimental organism
D. melanogaster
Olivia S Rissland

University of Colorado School of Medicine, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Developmental Biology

Research focus
post-transcriptional regulation
RNA
translation
maternal-to-zygotic transition
small RNAs
RNA decay

Experimental organism
drosophila
Sergio Ruiz Macias

National Cancer Institute, NIH, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Stem Cells and Regenerative Medicine

Research focus
embryonic stem cells
pluripotency
totipotency
chromatin
transcription factors

Experimental organism
mouse
Tamer I Sallam

University of California, Los Angeles, United States

Expertise
Medicine
Genetics and Genomics

Research focus
atherosclerosis
lipid metabolism
cardiovascular disease
noncoding RNA
gene regulation
Marcus M Seldin

University of California, Irvine, United States

Expertise
Biochemistry and Chemical Biology
Computational and Systems Biology
Genetics and Genomics

Research focus
systems genetics
endocrine physiology
metabolism
cell-cell communication
Reut Shalgi

Technion - Israel Institute of Technology, Israel

Expertise
Cell Biology
Genetics and Genomics
Computational and Systems Biology
Chromosomes and Gene Expression

Research focus
stress response
ER stress
UPR
heat shock response
chaperones
protein aggregation
Xiaohua Shen

Tsinghua University, China

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
non-coding RNA
RNA binding proteins
Jiwon Shim

Seoul National University of Science and Technology, South Korea

Expertise
Cell Biology
Developmental Biology
Genetics and Genomics
Immunology and Inflammation

Research focus
hematopoiesis
innate immunity
hemocyte
development
signaling
inter-organ communication

Experimental organism
D. melanogaster
Wenying Shou

University College London, United Kingdom

Expertise
Computational and Systems Biology
Ecology
Evolutionary Biology
Genetics and Genomics

Research focus
quantitative biology
mathematical biology
evolutionary biology
synthetic biology
molecular genetics
evolution of cooperation
computer simulations

Experimental organism
S. cerevisiae
Viji Subramanian

Indian Institute of Science Education and Research Tirupati, India

Expertise
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
chromosome segregation
meiosis
DNA repair and recombination
chromosome structure and dynamics
genome integrity
crossover
Owen Tamplin

University of Wisconsin-Madison, United States

Expertise
Genetics and Genomics
Developmental Biology
Stem Cells and Regenerative Medicine

Research focus
hematopoeitic stem cells
microenvironment
zebrafish
blood development
Kristin Tessmar-Raible

University of Vienna, Austria

Expertise
Cell Biology
Developmental Biology
Ecology
Evolutionary Biology
Genetics and Genomics
Neuroscience

Research focus
chronobiology
marine
photobiology
rhythms
clocks
physiology

Experimental organism
platynereis
clunio
danio
medakafish
oryzias
Summer Thyme

University of Massachusetts Medical School, United States

Expertise
Biochemistry and Chemical Biology
Chromosomes and Gene Expression
Developmental Biology
Genetics and Genomics
Neuroscience

Research focus
neurodevelopment
neurogenetics
CRISPR/Cas9
RNA
single cell RNA sequencing
behavior

Experimental organism
zebrafish
Kenichi Tsuda

Huazhong Agricultural University, China

Expertise
Plant Biology
Chromosomes and Gene Expression
Genetics and Genomics
Microbiology and Infectious Disease

Research focus
plant immunity
phytohormones
pathogen
microbiome
transcriptome

Experimental organism
maize
Arabidopsis
Pseudomonas
xanthomonas
Jenny Tung

Duke University, United States

Expertise
Ecology
Evolutionary Biology
Genetics and Genomics

Research focus
social behaviour
evolutionary ecology
evolutionary functional genomics
hybridization

Experimental organism
primates
Ashley Webb

Buck Institute for Research on Aging, United States

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Neuroscience
Stem Cells and Regenerative Medicine

Research focus
aging
epigenetics
gene regulation
stem cells
hypothalamus

Experimental organism
mouse
Alyssa M Wilson

Icahn School of Medicine at Mount Sinai, United Kingdom

Expertise
Neuroscience
Cell Biology
Genetics and Genomics
Chromosomes and Gene Expression
Computational and Systems Biology

Research focus
single cell biology
multi-omics
neuroinformatics
cellular neuroanatomy
disease-related neurodegeneration
bioinformatics methods development

Experimental organism
human
mouse
Jian Xu

St. Jude Children's Research Hospital, United States

Expertise
Cancer Biology
Chromosomes and Gene Expression
Developmental Biology
Genetics and Genomics
Stem Cells and Regenerative Medicine

Research focus
hematopoiesis
erythropoiesis
myeloid leukemia
epigenetics
transcription regulation
enhancer
metabolism

Experimental organism
human
mouse
Hao Yu

National University of Singapore & Temasek Life Sciences Laboratory, Singapore

Expertise
Genetics and Genomics
Plant Biology

Research focus
functional genomics
plant reproductive development
phytohormone signalling

Experimental organism
rice
orchid
A. thaliana
María Mercedes Zambrano

CorpoGen, Colombia

Expertise
Microbiology and Infectious Disease
Genetics and Genomics

Research focus
environmental microbiology
microbial communities
biodiversity
microbiome
antimicrobial resistance
extreme environments
Meet Zandawala

University of Nevada, Reno, United States

Expertise
Neuroscience
Genetics and Genomics

Research focus
neuropeptides
feeding
metabolism
GPCRs
endocrinology
osmoregulation

Experimental organism
Drosophila
invertebrates
Siming Zhao

Dartmouth College, United States

Expertise
Medicine
Computational and Systems Biology
Genetics and Genomics

Research focus
statistical genetics
genomics
human genetics
sequencing data
Yu Zhao

Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, China

Expertise
Biochemistry and Chemical Biology
Cancer Biology
Chromosomes and Gene Expression
Genetics and Genomics

Research focus
prostate cancer
noncoding RNA
m6A
epigenetics
enhancer
DNA damage
senescence
radiotherapy
Han Zhu

University of Colorado Anschutz Medical Campus, United States

Expertise
Cell Biology
Chromosomes and Gene Expression
Developmental Biology
Genetics and Genomics
Stem Cells and Regenerative Medicine

Research focus
pluripotent stem cells
human embryonic cells
human organoid
stem cell derived pancreatic islets
pancreatic islet development
pancreatic islet function
diabetes
gene regulation
single-cell genomics
Daniel Zilberman

John Innes Centre, United Kingdom

Expertise
Chromosomes and Gene Expression
Genetics and Genomics
Plant Biology

Research focus
DNA methylation
chromatin
epigenetics
epigenomics
evolution

Experimental organism
rice
A. thaliana
Moussa Zouache

University of Utah, United States

Expertise
Computational and Systems Biology
Medicine
Epidemiology and Global Health
Genetics and Genomics
Neuroscience
Physics of Living Systems

Research focus
visual neuroscience
population genetics
transcriptomics
proteomics
biology of aging
mathematical modelling
clinical research