Editors for Genetics and Genomics

eLife aims to publish significant research in areas including the genetic basis of health and disease, chromatin and chromosome biology, comparative and functional genomics, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. We welcome studies in all areas of human genetics as well as those that use cellular and animal models to explore traits of broad relevance to health and disease. We are particularly keen to see studies that use human genetics to drive risk variant discovery, and/or apply such information to provide further mechanistic insights into disease biology, to dissect the genetic architecture of disease, to explore the impact of modifiable risk factors, and/or to support translational advances. Read the latest research in this subject area.

Senior editors

  1. Mark McCarthy

    Mark McCarthy

    Senior Editor

    Mark McCarthy is the Robert Turner Professor of Diabetes Medicine at the University of Oxford, based at the Oxford Centre for Diabetes, Endocrinology, and Metabolism and the Wellcome Trust Centre for Human Genetics. He is also a Consultant Physician at the Oxford University Hospitals Trust and is currently Visiting Professor at the University of Geneva. Following medical training in Cambridge and London, a spell as an MRC Travelling Fellow at the Whitehead Institute in Massachusetts, and 8 years at Imperial College, he moved to Oxford in 2002. He is a physician-scientist and human geneticist interested in the biological basis of complex disease. His research group is focused on the identification and characterisation of genetic variants influencing risk of type 2 diabetes and related traits, and on using those discoveries to drive biological inference and translational opportunities. He works closely with colleagues in Oxford and beyond to establish the mechanisms whereby T2D-risk variants influence islet function, and to explore the value of this information to drive clinical advances. He has played a major role in establishing and leading a number of the global initiatives in this field including the DIAGRAM, MAGIC, GIANT, EGG, GoT2D, ENGAGE, and T2D-GENES consortia. He has been a Senior Editor at eLife since 2015.

    Expertise
    Genetics and Genomics
    Research focus
    genetics
    metabolism
    genome wide association and resequencing studies
    systems biology
    human genetics and genomics
    multifactorial disease
    metabolic disease
    biomarkers
    Competing interests statement
    Mark McCarthy has received funding from the UK Medical Research Council, Wellcome Trust, Diabetes UK, British Heart Foundation, the (UK) National Institute for Health Research, the (US) National Institutes of Health, the European Commission, the Foundation of the NIH, the Juvenile Diabetes Research Foundation, and from the Innovative Medicines Initiative. He is a member of the Scientific Advisory Boards (or equivalent advisory committees) for the Wellcome Trust Sanger Institute (Human Genetics), the H3A Bionet, and Genome Quebec. He is a member of the MRC Population and Systems Medicine Board and Cross Board Cohort Advisory Group. He has, via the IMI, received research funding, and/or has research collaborations with multiple pharma companies including Pfizer, Lilly, Sanofi-Aventis, NovoNordisk, and Boehringer Ingelheim.
  2. Aviv Regev

    Aviv Regev

    Senior Editor

    Aviv Regev is a computational biologist who joined the Broad Institute as a core member and MIT as a faculty member in 2006. Her work investigates how complex molecular networks function and evolve in the face of genetic and environmental changes, over time-scales ranging from minutes to millions of years. Regev received her MSc from Tel Aviv University, studying biology, computer science, and mathematics in the Interdisciplinary Program for the Fostering of Excellence, where she undertook research in both theoretical and experimental biology. She received her PhD in computational biology from Tel Aviv University. Prior to joining the Broad Institute, Regev was a fellow at the Bauer Center for Genomics Research at Harvard University, where she developed new approaches to the reconstruction of regulatory networks and modules from genomic data. Regev is also an associate professor in the Department of Biology at MIT
and director of the Klarman Cell Observatory at the Broad. Regev is the Director of the Cell Circuits Program at the Broad and a lead principal investigator for the Center for Cell Circuits at the Broad Institute, a Center of Excellence in Genomic Science (CEGS). Regev has been a Howard Hughes Medical Institute (HHMI) Early Career Scientist since 2009, and was named a Howard Hughes Medical Institute (HHMI) Investigator in 2013. She is a recipient of the NIH Director’s Pioneer Award, a Sloan fellowship from the Sloan Foundation, the Overton Prize from the International Society for Computational Biology, and the Earl and Thressa Stadtman Scholar Award from the American Society for Biochemistry and Molecular Biology (ASBMB).

    (Image Credit: Maria Nemchuk)

    Expertise
    Computational and Systems Biology
    Genetics and Genomics
    Chromosomes and Gene Expression
    Evolutionary Biology
    Cancer Biology
    Research focus
    systems biology
    molecular networks
    computational biology
    single cell genomics
    regulatory networks
    systems immunology
    gene regulation
    evolution
    Competing interests statement
    Aviv Regev receives funding from the Howard Hughes Medical Institute, the National Institutes of Health, and the Sloan Foundation. She is on the external advisory board of the San Diego Center for Systems Biology, the FAS Center for Systems Biology at Harvard, the Simons Institute for the Theory of Computing, the Jackson Laboratory, the European Molecular Biology Lab (EMBL), the SciLife Lab in Sweden, and ThermoFisher Scientific. She is on the advisory editorial board of Molecular Systems Biology and is an editorial board member of Genome Biology and Development. Regev is a consultant for Syros Phramaceuticals, GenePeeks, and CTIG (Cancer Therapeutics Innovation Group). Regev also worked for several years in the biotech industry in Israel, where she established and directed a bioinformatics research and development team at QBI, a functional genomics company.
  3. Diethard Tautz

    Senior Editor

    Diethard Tautz is since 2006 Director of the Department for Evolutionary Genetics at the Max-Planck Institute for Evolutionary Biology in Plön, Germany. He did his PhD at the EMBL in Heidelberg, followed by postdoc phases on molecular evolution in Cambridge (UK) and on the molecular analysis of developmental processes in Drosophila at the MPI for Developmental Biology in Tübingen, where he joined the group of Herbert Jäckle. In 1991 he became Professor in the Department of Zoology in Munich and in 1998 he moved to a chair in "Evolutionary Genetics" at the Department of Genetics of the University of Cologne. In his research, he combined his interests in molecular evolution and developmental biology, and was one of the founders of the emerging Evo-Devo field. In parallel, he worked on questions of behavioral ecology and speciation mechanisms, based on his discovery of microsatellite-based DNA fingerprinting. His current interests center around studying the genetics of adaptations, using wild populations of the house mouse as a model system. He is also continuing his work on molecular evolution, with a special emphasis on the de novo evolution of genes. He has served as Editor-in-Chief for Development, Genes and Evolution, and was a co-founder of the open-access journal Frontiers in Zoology.

    Expertise
    Evolutionary Biology
    Genetics and Genomics
    Research focus
    evolutionary genetics
    population genomics
    molecular evolution
    evolution of development
    comparative genomics
    adaptation
    behavioral ecology
    speciation
    Competing interests statement
    Diethard Tautz is funded by the Max-Planck Society and the European Research Council. He currently serves as Senior Editor for Molecular Ecology and on the editorial board of Frontiers in Zoology, Development Genes and Evolution, and Briefings in Functional Genomics and Proteomics. He served on a number of Max-Planck committees and on the evaluation committees for academic institutions.
  4. Patricia Wittkopp

    Senior Editor

    Patricia Wittkopp received a BS from the University of Michigan, a PhD from the University of Wisconsin, and did postdoctoral work at Cornell University. In 2005, she began a faculty position at the University of Michigan, where she is now an Arthur F Thurnau Professor in the Department of Ecology and Evolutionary Biology, Department of Molecular, Cellular, and Developmental Biology, Center for Computational Medicine and Bioinformatics, and LSA Honors Program. Her research investigates the genetic basis of phenotypic evolution, with an emphasis on the evolution of gene expression. Molecular and developmental biology, population and quantitative genetics, genomics and bioinformatics are integrated in this work. She was a Damon Runyon Cancer Research Fellow, an Alfred P Sloan Research Fellow, and a recipient of a March of Dimes Starter Scholar Award.

    Expertise
    Computational and Systems Biology
    Ecology
    Genetics and Genomics
    Evolutionary Biology
    Research focus
    evolutionary genetics
    evolution and development
    gene expression
    regulatory networks
    allele-specific expression
    Competing interests statement
    Patricia Wittkopp has received research support from the National Institutes of Health, National Science Foundation, March of Dimes, and the Alfred P Sloan Foundation. She is currently an Associate Editor of Molecular Biology and Evolution and Genome Biology and Evolution, and also serves on the Advisory Editorial Board of Trends in Genetics.

Reviewing editors

  1. Chris Ponting

    University of Edinburgh, United Kingdom

    Expertise
    Computational and Systems Biology
    Genetics and Genomics
    Research focus
    evolutionary genomics
    long non-coding RNAs
    functional genomics
    transcriptomics
    Experimental organism
    D. melanogaster
    human
    mouse
  2. Julie Ahringer

    Cambridge University, United Kingdom

    Expertise
    Genetics and Genomics
    Research focus
    cell fate
    gene expression
    chromatin biology
    epigenetics
    Experimental organism
    C. elegans
  3. Asifa Akhtar

    Max Planck Institute for Immunobiology and Epigenetics, Germany

    Expertise
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    gene expression
    chromatin biology
    epigenetics
    transcription
    Experimental organism
    Drosophila
  4. Richard Amasino

    University of Wisconsin, United States

    Expertise
    Plant Biology
    Genetics and Genomics
    Research focus
    plant development and epigenetics
    Experimental organism
    arabidopsis thaliana
    brachypodium distachyon
  5. David Baulcombe

    Cambridge University, United Kingdom

    Expertise
    Genetics and Genomics
    Plant Biology
    Research focus
    epigenetics
    RNA silencing
    plant microbe interactions and signaling
    Experimental organism
    arabidopsis thaliana
  6. Benjamin J Blencowe

    University of Toronto, Canada

    Expertise
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    RNA processing
    epigenomics
    transcriptome analyses
  7. Jörg Bohlmann

    University of British Columbia, Canada

    Expertise
    Ecology
    Genetics and Genomics
    Plant Biology
    Research focus
    metabolism
    chemical ecology
    plant genomics
    Experimental organism
    plants
  8. Jonathan Flint

    University of California, Los Angeles, United States

    Expertise
    Genetics and Genomics
    Human Biology and Medicine
    Research focus
    genetics
    psychiatric disorders
  9. Thomas Gingeras

    Cold Spring Harbor Laboratory, United States

    Expertise
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    noncoding RNA
    genome organisation
    transcriptome analyses
    DNA sequencing methods
    Experimental organism
    Drosophila
  10. Daniel J Kliebenstein

    University of California, Davis, United States

    Expertise
    Ecology
    Genetics and Genomics
    Plant Biology
    Research focus
    plant-microbe interactions
    quantitative biology
    genome-wide association studies
    plant genomics
    ecological genomics
    fungal cell cycle and morphogenesis
    secondary metabolism
    plant-insect interactions
  11. Andrew Morris

    University of Liverpool, United Kingdom

    Expertise
    Computational and Systems Biology
    Genetics and Genomics
    Research focus
    statistical genetics
    genetic epidemiology
    methodological development
    genome-wide association studies
  12. Sacha B Nelson

    Brandeis University, United States

    Expertise
    Genetics and Genomics
    Neuroscience
    Research focus
    genome-wide gene expression in the nervous system
    cellular and systems neurophysiology
    forebrain development and function
    synaptic plasticity
    Experimental organism
    other mammals
  13. Magnus Nordborg

    Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Austria

    Expertise
    Genetics and Genomics
    Plant Biology
    Evolutionary Biology
    Research focus
    adaptation
    population genetics
    statistical genetics
    molecular genetics
  14. Molly Przeworski

    Columbia University, United States

    Expertise
    Computational and Systems Biology
    Evolutionary Biology
    Genetics and Genomics
    Research focus
    population genetics
    evolutionary biology
    recombination
    Experimental organism
    primates
  15. Jerry L Workman

    Stowers Institute for Medical Research, United States

    Expertise
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    protein complexes
    chromatin modification
    regulation of gene transcription
    Experimental organism
    S. cerevisiae
  16. Hao Yu

    National University of Singapore & Temasek Life Sciences Laboratory, Singapore

    Expertise
    Genetics and Genomics
    Plant Biology
    Research focus
    functional genomics
    plant reproductive development
    phytohormone signalling
    Experimental organism
    rice
    orchid
    arabidopsis thaliana
  17. Daniel Zilberman

    John Innes Centre, United Kingdom

    Expertise
    Chromosomes and Gene Expression
    Genetics and Genomics
    Plant Biology
    Research focus
    chromatin biology
    epigenetics
    epigenomics
    evolution
    Experimental organism
    rice
    arabidopsis thaliana