Genetics and Genomics

Latest articles

1. 1. Microbiology and Infectious Disease
   2. Genetics and Genomics

   Dissection of the in vitro developmental program of Hammondia hammondi reveals a link between stress sensitivity and life cycle flexibility in Toxoplasma gondii.

   Sarah L Sokol et al.

   A derived stress response trait may have contributed to the emergence of a globally dominant and promiscuous parasite.
2. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Neolithic and Medieval virus genomes reveal complex evolution of Hepatitis B

   Ben Krause-Kyora et al.
3. 1. Genetics and Genomics

   Determining the genetic basis of anthracycline-cardiotoxicity by response QTL mapping in induced cardiomyocytes

   David A Knowles et al.
4. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Transmission genetics of drug-resistant hepatitis C virus

   Nicholas van Buuren et al.

   Interactions between viral genomes within the same cells can impact the selection of drug-resistant variants and this has been finessed by hepatitis C virus.
5. 1. Genetics and Genomics

   An incoherent feedforward loop facilitates adaptive tuning of gene expression

   Jungeui Hong et al.

   The architecture of a gene regulatory network determines the effect of evolutionary changes in transcription factor binding.
6. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

   Sona Gregorova et al.

   Prdm9-generated meiotic asynapsis of homologous chromosomes in mouse subspecific hybrids causes hybrid sterility and can be reversed by introducing random stretches of consubspecific sequence (≥ 27Mb) on four chromosomes most sensitive to asynapsis.
7. 1. Genetics and Genomics

   Normal mitochondrial function in Saccharomyces cerevisiae has become dependent on inefficient splicing

   Marina Rudan et al.

   Removal of mitochondrial introns (Saccharomyces cerevisiae) from their host genes leads to detrimental increase in their transcript levels.
8. 1. Genetics and Genomics

   Evidence for loss and reacquisition of alcoholic fermentation in a fructophilic yeast lineage

   Carla Gonçalves et al.

   Comparative genomics coupled with genetic and biochemical studies show that central carbon metabolism in fungi can be remodeled by genes originating from bacteria.
9. 1. Genetics and Genomics

   Codon usage biases co-evolve with transcription termination machinery to suppress premature cleavage and polyadenylation

   Zhipeng Zhou et al.

   Genetic and bioinformatic analyses uncover an unexpected role for codon usage biases in regulating gene expression at the transcriptional level by suppressing premature transcription termination.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology

    Yu Fu et al.

    The genome sequence of Trichoplusia ni enables the use of this widespread lepidopteran pest as a model for both the study of small RNA pathways and insecticide resistance.