Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics

    Mono-methylated histones control PARP-1 in chromatin and transcription

    Gbolahan Bamgbose, Guillaume Bordet ... Alexei Tulin
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Haplotype function score improves biological interpretation and cross-ancestry polygenic prediction of human complex traits

    Weichen Song, Yongyong Shi, Guan ning Lin
    Using sequence-determined functional genomic features instead of original genotypes can partially overcome challenges in genetic association studies, such as rare variant exclusion and population structure.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Transposable elements regulate thymus development and function

    Jean-David Larouche, Céline M Laumont ... Claude Perreault
    Multiomic analyses provide new insights into the involvement of transposable elements in T-cell development in the thymus and central tolerance induction.
    1. Developmental Biology
    2. Genetics and Genomics

    ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse

    Debashish U. Menon, Prabuddha Chakraborty ... Terry Magnuson
    1. Genetics and Genomics

    Deciphering the complex relationship between type 2 diabetes and fracture risk with both genetic and observational evidence

    Pianpian Zhao, Zhifeng Sheng ... Hou-Feng Zheng
    Genetically determined type 2 diabetes (T2D) may not increase the risk of fracture, but managing T2D-related risk factors is crucial to prevent fracture in patients with T2D.

Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Murim Choi
    Seoul National University College of Medicine, South Korea
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors