Genetics and Genomics

Latest articles

1. 1. Epidemiology and Global Health
   2. Genetics and Genomics

   Single mosquito metatranscriptomics identifies vectors, emerging pathogens and reservoirs in one assay

   Joshua Batson et al.

   How large-scale single mosquito metatranscriptomics can define the mosquito’s complex microbiota and its blood meal sources, and contribute critical epidemiological information needed to control vector borne disease transmission, is shown.
2. 1. Cancer Biology
   2. Genetics and Genomics

   Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

   Sibylle Mitschka, Christine Mayr
3. 1. Genetics and Genomics

   Whole-genome sequencing analysis of semi-supercentenarians

   Paolo Garagnani et al.

   Genetic variants located in DNA repair genes and a reduced burden of somatic mutations protect the oldest living persons from age-related diseases, allowing an healthy aging phenotype.
4. 1. Evolutionary Biology
   2. Genetics and Genomics

   High social status males experience accelerated epigenetic aging in wild baboons

   Jordan A Anderson et al.

   Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.
5. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Epigenetic analysis of Paget's disease of bone identifies differentially methylated loci that predict disease status

   Ilhame Diboun et al.
6. 1. Evolutionary Biology
   2. Genetics and Genomics

   Aging: The temporary cost of dominance

   Calen P Ryan, Christopher W Kuzawa

   In a population of wild baboons, a new way to assess biological age reveals a surprising effect of social hierarchy.
7. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   A spontaneous genetically induced epiallele at a retrotransposon shapes host genome function

   Tessa M Bertozzi et al.

   A retrotransposon-derived recombination event in inbred mice gives rise to an epiallele and tissue-specific phenotypes.
8. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

   Thomas J Etheridge et al.

   In vivo single-molecule imaging demonstrates that Smc5/6 chromatin association depends on ATP hydrolysis and dsDNA binding, requires Nse6 and is modulated by Brc1 after DNA damage.
9. 1. Genetics and Genomics
   2. Medicine

   A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease

   Qingyuan Zhao et al.
10. 1. Genetics and Genomics

    Whole-organism eQTL mapping at cellular resolution with single-cell sequencing

    Eyal Ben-David et al.

    The effect of genetic variation on gene expression can be specific down to the level of individual cells.