Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics
    2. Neuroscience

    Transposons contribute to splice-isoform diversity in the Drosophila brain

    Malak Choucri, Tina Rainey, Christoph D Treiber
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Developmental Biology
    grid of multicoloured bar graphs with vertical shaded areas in red and green highlighting specific columns

    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan
    eLife publishes research on the mechanisms and biological significance of environmentally driven epigenetic inheritance.
    1. Genetics and Genomics
    2. Neuroscience

    Learning is a fundamental source of individuality

    Riddha Manna, Johanni Brea ... Ana Marija Jakšić
    Beyond genotype × environment interactions, which can be shared and identical across individuals, learning from uniquely individual experiences further defines and diversifies individual behaviour.
    1. Genetics and Genomics
    2. Ecology

    Decomposition potential and population structure among active microbial communities in deep salt marsh sediments

    Joseph H Vineis, Ashley N Bulseco ... Jennifer L Bowen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

    Kuei Ching Hsiung, Hannah Chapman ... David Gems
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Parallel connectivity and genomic divergence but heterogeneous demographic history in sympatric Mediterranean clingfishes

    Maximilian Wagner, Stephan Koblmüller ... Hannes Svardal
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development

    Julia Raulino Lima, Nicha Ungvijanpunya ... Jian Xu
    IR-couple NMD controls matrix transcript abundance during craniofacial morphogenesis.
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations

    Boris Noyvert, A Mesut Erzurumluoglu ... Zhihao Ding
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    The hypoxic response extends lifespan through a bioaminergic and peptidergic neural circuit

    Elizabeth S Kitto, Shijiao Huang ... Scott F Leiser
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    The C. elegans gustatory receptor homolog LITE-1 is a chemoreceptor required for diacetyl avoidance

    Alan Koh, Eduard Bokman ... André EX Brown
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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Highlights

    1. Genetics and Genomics
    Microscopy image of a fruit fly. Image credit: USGS (CC0)

    How experience shapes individuality

    Bassem A Hassan
    1. Genetics and Genomics
    2. Medicine

    Responding to peer reviewers

    Eric Kalkhoven, Manon Kluijtmans
    1. Developmental Biology
    2. Genetics and Genomics

    Written out of history

    Lisa M Thomann, Julie Batut

Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Yamini Dalal
    National Cancer Institute, United States
  3. Dominique Soldati-Favre
    University of Geneva, Switzerland
  4. See more editors