Genetics and Genomics

Latest articles

1. 1. Genetics and Genomics
   2. Evolutionary Biology

   Positive epistasis for fitness under monosomy: Loss of ribosomal protein stoichiometry reduces the effects of other perturbations

   Hanna Tutaj, Katarzyna Tomala ... Ryszard Korona
2. 1. Genetics and Genomics

   Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways

   Shaohua Gu, Yuanzhe Shao ... Zhiyuan Li

   A novel bioinformatic pipeline predicts diverse pyoverdine structures and receptor groups with high accuracy, revealing significant hidden diversity in siderophores systems across Pseudomonas genomes.
3. 1. Genetics and Genomics
   2. Computational and Systems Biology

   DGRPool: A web tool leveraging harmonized Drosophila Genetic Reference Panel phenotyping data for the study of complex traits

   Vincent Gardeux, Roel PJ Bevers ... Bart Deplancke
4. 1. Developmental Biology
   2. Genetics and Genomics

   Caspar specifies primordial germ cell count and identity in Drosophila melanogaster

   Subhradip Das, Sushmitha Hegde ... Girish S Ratnaparkhi
5. 1. Genetics and Genomics

   Confirmation of HLA-II associations with TB susceptibility in admixed African samples

   Dayna Croock, Yolandi Swart ... Caitlin Uren
6. 1. Genetics and Genomics
   2. Evolutionary Biology

   Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

   James Boocock, Noah Alexander ... Leonid Kruglyak
7. 1. Genetics and Genomics

   Sibling Similarity Can Reveal Key Insights into Genetic Architecture

   Tade Souaiaia, Hei Man Wu ... Paul O’Reilly
8. 1. Genetics and Genomics
   2. Neuroscience

   Impact of liver specific survival motor neuron (SMN) depletion on peripheral and central nervous system tissue pathology

   Monique Marylin Alves de Almeida, Yves De Repentigny ... Rashmi Kothary
9. 1. Cancer Biology
   2. Genetics and Genomics

   Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases

   Joakim W Karlsson, Vasu R Sah ... Jonas A Nilsson

   Single-cell sequencing and functional analysis identify T cells that can be useful for marker selection and cell therapy in uveal melanoma, a disease largely unresponsive to conventional immune checkpoint therapies.
10. 1. Genetics and Genomics
    2. Evolutionary Biology

    Refining the resolution of the yeast genotype-phenotype map using single-cell RNA-sequencing

    Arnaud N’Guessan, Wen Yuan Tong ... Alex N Nguyen Ba