Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Computational and Systems Biology
    2. Genetics and Genomics

    Spotless, a reproducible pipeline for benchmarking cell type deconvolution in spatial transcriptomics

    Chananchida Sang-aram, Robin Browaeys ... Yvan Saeys
    Estimating cell type composition from a gene expression mixture remains a challenging task, as evidenced by how a simple regression model outperforms many state-of-the-art spatial deconvolution methods.
    1. Genetics and Genomics
    2. Neuroscience

    Biobank-wide association scan identifies risk factors for late-onset Alzheimer’s disease and endophenotypes

    Donghui Yan, Bowen Hu ... Qiongshi Lu
    BADGERS, as a new powerful method for conducting polygenic score-based biobank-wide association scans, identified 48 significant associations for AD and 41 significant associations for a variety of AD endophenotypes.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Signatures of transposon-mediated genome inflation, host specialization, and photoentrainment in Entomophthora muscae and allied entomophthoralean fungi

    Jason E Stajich, Brian Lovett ... Carolyn Elya
    Entomophthora muscae has one of the largest fungal genomes (1.03 Gb) owing to extensive proliferation of transposable elements.

Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Benoît Kornmann
    University of Oxford, United Kingdom
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors