Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Genetics and Genomics
    2. Computational and Systems Biology

    The impact of ambient contamination on demultiplexing methods for single-nucleus multiome experiments

    Terence Li, Marcus Alvarez ... Noah Zaitlen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    G protein-coupled receptor diversity and evolution in the closest living relatives of Metazoa

    Alain Garcia De Las Bayonas, Nicole King
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Evolutionary Biology

    Refining the resolution of the yeast genotype-phenotype map using single-cell RNA-sequencing

    Arnaud N’Guessan, Wen Yuan Tong ... Alex N Nguyen Ba
    Revised
    Reviewed Preprint v4
    Updated
    • Useful
    • Convincing
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Benchmarking and Optimization of Methods for the Detection of Identity-By-Descent in High-Recombining Plasmodium falciparum Genomes

    Bing Guo, Shannon Takala-Harrison, Timothy D O’Connor
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    Ancient Trans-Species Polymorphism at the Major Histocompatibility Complex in Primates

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice

    Laura Sophie Kremer, Guanbin Gao ... Nils-Göran Larsson
    Regulation of mitochondrial DNA copy number is highly tissue-specific and context-dependent, particularly in the presence of disease.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Divergent C. elegans toxin alleles are suppressed by distinct mechanisms

    Stefan Zdraljevic, Laura Walter-McNeill ... Leonid Kruglyak
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Minus the Error: Testing for Positive Selection in the Presence of Residual Alignment Errors

    Avery Selberg, Nathan L Clark ... Sergei L Kosakovsky Pond
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    ADMA-histones play a crucial role in the initial recognition of dual-strand piRNA cluster regions by Rhino

    Raku Saito, Hirotsugu Ishizu ... Mikiko C Siomi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    WRN and WRNIP1 ATPases impose high fidelity on translesion synthesis by Y-family DNA polymerases

    Jung-Hoon Yoon, Karthi Sellamuthu ... Satya Prakash
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

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Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Murim Choi
    Seoul National University College of Medicine, South Korea
  3. Yamini Dalal
    National Cancer Institute, United States
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