Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Evolutionary Biology
    2. Genetics and Genomics

    The genomic footprint of social stratification in admixing American populations

    Alex Mas Sandoval, Sara Mathieson, Matteo Fumagalli
    1. Genetics and Genomics

    Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis

    Hao Yu, Anas M. Khanshour ... Carol A. Wise
    1. Genetics and Genomics

    Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo

    Swati Gaikwad, Fardin Ghobakhlou ... Alan G. Hinnebusch
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Chromosome-specific maturation of the epigenome in the Drosophila male germline

    James T Anderson, Steven Henikoff, Kami Ahmad
    Chromatin profiling of Drosophila testes reveals activation of the transcriptional program of the germline, widespread changes in RNA polymerase progression, and the absence of chromosomal regulation across the X chromosome.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes

    Baira Godneeva, Maria Ninova ... Alexei Aravin
    Bonus, the Drosophila TIF1 factor, functions as a repressor of tissue-specific genes in the germline, emphasizing an important function of SUMOylation in transcriptional regulation.

Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Benoît Kornmann
    University of Oxford, United Kingdom
  3. Sacha B Nelson
    Brandeis University, United States
  4. See more editors