Genetics and Genomics

Latest articles

1. 1. Genetics and Genomics
   2. Medicine

   Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2,600 disease traits

   Joshua K Park, Shantanu Bafna ... Ron Do
2. 1. Epidemiology and Global Health
   2. Genetics and Genomics

   Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

   Peh Joo Ho, Iain BeeHuat Tan ... Jingmei Li
3. 1. Developmental Biology
   2. Genetics and Genomics

   Evidence for RNA or protein transport from somatic tissues to the male reproductive tract in mouse

   Vera RInaldi, Kathleen Messemer ... Oliver J Rando
4. 1. Genetics and Genomics

   Quantitative proteomic analysis of skeletal muscles from wild-type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies

   Jan Eckhardt, Alexis Ruiz ... Francesco Zorzato

   Quantitative proteomic analysis shows that recessive Ryr1 mutations not only decrease the content of RyR1 protein in muscle, but also affect the content of many other proteins involved in a variety of biological processes.
5. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Enterobacterales plasmid sharing amongst human bloodstream infections, livestock, wastewater, and waterway niches in Oxfordshire, UK

   William Matlock, Samuel Lipworth ... REHAB Consortium
6. 1. Genetics and Genomics
   2. Physics of Living Systems

   Coarsening dynamics can explain meiotic crossover patterning in both the presence and absence of the synaptonemal complex

   John A Fozard, Chris Morgan, Martin Howard

   Mathematical modelling, together with super-resolution imaging in Arabidopsis, demonstrates that a recently proposed coarsening model for meiotic crossover interference can explain the dynamic patterning of crossovers in many contexts, including in zyp1 and pch2 chromosome structure mutants.
7. 1. Genetics and Genomics
   2. Neuroscience

   Nutrigenomic regulation of sensory plasticity

   Hayeon Sung, Anoumid Vaziri ... Monica Dus

   Nutrient and activity-responsive pathways converge on chromatin to drive neural adaptations to the food environment.
8. 1. Genetics and Genomics
   2. Evolutionary Biology

   Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals

   Zane Kliesmete, Lucas Esteban Wange ... Wolfgang Enard

   Combining phylogenetic and functional approaches, it is shown that the protein sequence, the proliferative activity, and a regulatory element of TRNP1 co-evolve with brain size and folding.
9. 1. Evolutionary Biology
   2. Genetics and Genomics

   The lingering effects of Neanderthal introgression on human complex traits

   Xinzhu Wei, Christopher R Robles ... Sriram Sankararaman
10. 1. Genetics and Genomics

    Native functions of short tandem repeats

    Shannon E Wright, Peter K Todd

    The mechanisms by which non-pathologic short tandem repeats normally influence gene expression and engender rapid genetic variation across phylogeny directly inform how expansions in these same repeats elicit neurological disease.