Genetics and Genomics

Genetics and Genomics

eLife publishes research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Single mosquito metatranscriptomics identifies vectors, emerging pathogens and reservoirs in one assay

    Joshua Batson et al.
    How large-scale single mosquito metatranscriptomics can define the mosquito’s complex microbiota and its blood meal sources, and contribute critical epidemiological information needed to control vector borne disease transmission, is shown.
    1. Genetics and Genomics

    Whole-genome sequencing analysis of semi-supercentenarians

    Paolo Garagnani et al.
    Genetic variants located in DNA repair genes and a reduced burden of somatic mutations protect the oldest living persons from age-related diseases, allowing an healthy aging phenotype.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High social status males experience accelerated epigenetic aging in wild baboons

    Jordan A Anderson et al.
    Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Aging: The temporary cost of dominance

    Calen P Ryan, Christopher W Kuzawa
    In a population of wild baboons, a new way to assess biological age reveals a surprising effect of social hierarchy.
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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A spontaneous genetically induced epiallele at a retrotransposon shapes host genome function

    Tessa M Bertozzi et al.
    A retrotransposon-derived recombination event in inbred mice gives rise to an epiallele and tissue-specific phenotypes.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

    Thomas J Etheridge et al.
    In vivo single-molecule imaging demonstrates that Smc5/6 chromatin association depends on ATP hydrolysis and dsDNA binding, requires Nse6 and is modulated by Brc1 after DNA damage.
    1. Genetics and Genomics

    Whole-organism eQTL mapping at cellular resolution with single-cell sequencing

    Eyal Ben-David et al.
    The effect of genetic variation on gene expression can be specific down to the level of individual cells.

Senior editors

  1. Naama Barkai
    Naama Barkai
    Weizmann Institute of Science, Israel
  2. Matt Kaeberlein
    University of Washington, United States
  3. George H Perry
    Pennsylvania State University, United States
  4. See more editors