Genetics and Genomics

Genetics and Genomics

eLife publishes research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Evolutionary Biology
    2. Genetics and Genomics

    Admixture of evolutionary rates across a butterfly hybrid zone

    Tianzhu Xiong et al.
    Genetic barriers to gene flow maintain divergent linked substitution rates in hybridization.
    1. Genetics and Genomics

    An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

    Oguz Kanca et al.
    New construct designs and gene targeting strategies from the Gene Disruption Project allow efficient tagging of almost all Drosophila genes.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing

    Jayashree Kumar et al.
    A novel model is presented that reconciles in-cell structure probing data with splicing regulatory elements to predict exon 10 inclusion of the Tau gene with high accuracy for 53 splice altering mutations.
    1. Genetics and Genomics

    Quantifying concordant genetic effects of de novo mutations on multiple disorders

    Hanmin Guo et al.
    EncoreDNM identifies abundant enrichment correlations across disorders for de novo mutations.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Rapid adaptation of a complex trait during experimental evolution of Mycobacterium tuberculosis

    Tracy M Smith et al.
    Mycobacterium tuberculosis, which causes tuberculosis, can evolve rapidly in response to new environments by mutating genetic regulators that control multiple genes at once.

Senior editors

  1. Naama Barkai
    Naama Barkai
    Weizmann Institute of Science, Israel
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Benoît Kornmann
    University of Oxford, United Kingdom
  4. See more editors