Genetics and Genomics

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability

   Leon Y Chan et al.

   Non-invasive mRNA stability measurements reveal that transcript lifetime is governed by a competition with translation initiation on a transcriptome-wide level.
2. 1. Genetics and Genomics

   Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila

   Johannes Bischof et al.
3. 1. Genetics and Genomics

   Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

   Niko Välimäki et al.
4. 1. Developmental Biology
   2. Genetics and Genomics

   Efficient single-copy HDR by 5’ modified long dsDNA donors

   Jose Arturo Gutierrez-Triana et al.

   The 5' modification of the donor template facilitates highly efficient Crispr targeted homologous recombination and at the same time favors single copy integration.
5. 1. Developmental Biology
   2. Genetics and Genomics

   Epigenetic age-predictor for mice based on three CpG sites

   Yang Han et al.
6. 1. Genetics and Genomics

   Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences

   Fanny Pouyet et al.
7. 1. Genetics and Genomics

   An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila

   David Li-Kroeger et al.

   New technology for manipulating genes in Drosophila facilitates gene tagging and precise modification of virtually any gene.
8. 1. Evolutionary Biology
   2. Genetics and Genomics

   Evolution of gene dosage on the Z-chromosome of schistosome parasites

   Marion A L Picard et al.

   An analysis of gene dosage at the DNA, RNA and protein level yields new insights into the early stages of Z-chromosome dosage compensation in schistosome parasites.
9. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Genetics of trans-regulatory variation in gene expression

   Frank Wolfgang Albert et al.

   A genetic mapping study in more than 1000 yeast individuals reveals the complexity of trans-acting genetic influences on transcriptome variation in unprecedented depth and detail.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation

    Daniel R Fuentes et al.