Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics
    2. Evolutionary Biology

    Ancient Trans-Species Polymorphism at the Major Histocompatibility Complex in Primates

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice

    Laura Sophie Kremer, Guanbin Gao ... Nils-Göran Larsson
    Regulation of mitochondrial DNA copy number is highly tissue-specific and context-dependent, particularly in the presence of disease.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Divergent C. elegans toxin alleles are suppressed by distinct mechanisms

    Stefan Zdraljevic, Laura Walter-McNeill ... Leonid Kruglyak
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Minus the Error: Testing for Positive Selection in the Presence of Residual Alignment Errors

    Avery Selberg, Nathan L Clark ... Sergei L Kosakovsky Pond
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    ADMA-histones play a crucial role in the initial recognition of dual-strand piRNA cluster regions by Rhino

    Raku Saito, Hirotsugu Ishizu ... Mikiko C Siomi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    WRN and WRNIP1 ATPases impose high fidelity on translesion synthesis by Y-family DNA polymerases

    Jung-Hoon Yoon, Karthi Sellamuthu ... Satya Prakash
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

    Tom Bonnifet, Sandra Sinnassamy ... Julia Fuchs
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Deletion of the moeA gene in Flavobacterium IR1 drives structural color shift from green to blue and alters polysaccharide metabolism

    Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology

    Alan Monziani, Juan Pablo Unfried ... Igor Ulitsky
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics

    Independent Validation of Transgenerational Inheritance of Learned Pathogen Avoidance in Caenorhabditis elegans

    Aalimah Akinosho, Joseph Alexander ... Andrés Vidal-Gadea
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
Load more

Highlights

    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

    Submit to our latest special issue in systems genetics

    1. Genetics and Genomics
    2. Neuroscience
    hands typing on a laptop keyboard

    Read public reviews for ‘A “tour-de-force” study of neuronal maturation’

    1. Genetics and Genomics

    Quantitative Genetics: Explore our collection of articles

    Edited by Patricia Wittkopp et al.

Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Yamini Dalal
    National Cancer Institute, United States
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors