Genetics and Genomics

Genetics and Genomics

eLife publishes research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics

    One-step efficient generation of dual-function conditional knockout and geno-tagging alleles in zebrafish

    Wenyuan Li et al.
    Conditional gene knockout in combination with fluorescent labeling of different alleles can be achieved with high efficiency in zebrafish through NHEJ-mediated targeted insertion using a CRISPR/Cas system.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    SCGN deficiency results in colitis susceptibility

    Luis F Sifuentes-Dominguez et al.
    A novel mutation in SCGN is associated with risk for inflammatory bowel disease and implicates the intestinal neuroendocrine compartment in the pathogenesis of this disorder.
    1. Developmental Biology
    2. Genetics and Genomics

    The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila

    Youheng Wei et al.
    The GATOR complex regulates TORC1 activity during meiosis.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Philosophy of Biology: The meanings of 'function' in biology and the problematic case of de novo gene emergence

    Diane Marie Keeling et al.
    A lexicon to help scientists and philosophers discuss the meaning of function in molecular biology more clearly is proposed.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Comment on 'Single nucleus sequencing reveals evidence of inter-nucleus recombination in arbuscular mycorrhizal fungi'

    Benjamin Auxier, Anna Bazzicalupo
    We are writing to comment on the article by Chen et al. (2018) about inter-nucleus recombination in arbuscular mycorrhizal fungi.

Senior editors

  1. Naama Barkai
    Naama Barkai
    Weizmann Institute of Science, Israel
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Mike Eisen
    Michael B Eisen
    HHMI, University of California, Berkeley, United States
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