Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics

    Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways

    Shaohua Gu, Yuanzhe Shao ... Zhiyuan Li
    A novel bioinformatic pipeline predicts diverse pyoverdine structures and receptor groups with high accuracy, revealing significant hidden diversity in siderophores systems across Pseudomonas genomes.
    1. Developmental Biology
    2. Genetics and Genomics

    Caspar specifies primordial germ cell count and identity in Drosophila melanogaster

    Subhradip Das, Sushmitha Hegde ... Girish S Ratnaparkhi
    1. Genetics and Genomics

    Confirmation of HLA-II associations with TB susceptibility in admixed African samples

    Dayna Croock, Yolandi Swart ... Caitlin Uren
    1. Genetics and Genomics
    2. Evolutionary Biology

    Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

    James Boocock, Noah Alexander ... Leonid Kruglyak
    1. Genetics and Genomics

    Sibling Similarity Can Reveal Key Insights into Genetic Architecture

    Tade Souaiaia, Hei Man Wu ... Paul O’Reilly
    1. Genetics and Genomics
    2. Neuroscience

    Impact of liver specific survival motor neuron (SMN) depletion on peripheral and central nervous system tissue pathology

    Monique Marylin Alves de Almeida, Yves De Repentigny ... Rashmi Kothary
    1. Cancer Biology
    2. Genetics and Genomics

    Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases

    Joakim W Karlsson, Vasu R Sah ... Jonas A Nilsson
    Single-cell sequencing and functional analysis identify T cells that can be useful for marker selection and cell therapy in uveal melanoma, a disease largely unresponsive to conventional immune checkpoint therapies.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Refining the resolution of the yeast genotype-phenotype map using single-cell RNA-sequencing

    Arnaud N’Guessan, Wen Yuan Tong ... Alex N Nguyen Ba

Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Murim Choi
    Seoul National University College of Medicine, South Korea
  3. Yamini Dalal
    National Cancer Institute, United States
  4. See more editors