Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics
    2. Evolutionary Biology

    Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

    Florian Bénitière, Anamaria Necsulea, Laurent Duret
    1. Genetics and Genomics
    2. Neuroscience

    Metabolic and neurobehavioral disturbances induced by purine recycling deficiency in Drosophila

    Céline Petitgas, Laurent Seugnet ... Serge Birman
    1. Genetics and Genomics

    Equity, Diversity and Inclusion: Targeted action to increase inclusion at the Wellcome Sanger Institute

    Saher Ahmed, David J Adams ... Maria Augusta Arruda
    The Sanger Excellence Fellowship has been established to increase the representation of researchers with Black-heritage backgrounds at a leading research centre in the UK.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Epistasis between mutator alleles contributes to germline mutation spectrum variability in laboratory mice

    Thomas A Sasani, Aaron R Quinlan, Kelley Harris
    Germline mutation rates in mice are shaped by two mutator alleles that interact epistatically, showing that DNA repair defects that map to different loci can have snowballing effects.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Cell-type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells

    Ban Wang, Alexander L Starr, Hunter B Fraser
    Exploring tissue-specific regulation of gene expression with human-chimpanzee hybrid cells helps us understand how life evolves and what makes us human.

Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Benoît Kornmann
    University of Oxford, United Kingdom
  3. Wei Yan
    University of California, Los Angeles, United States
  4. See more editors