Genetics and Genomics

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Sae2/CtIP prevents R-loop accumulation in eukaryotic cells

   Nodar Makharashvili et al.
2. 1. Evolutionary Biology
   2. Genetics and Genomics

   Drought adaptation in Arabidopsis thaliana by extensive genetic loss-of-function

   John Grey Monroe et al.
3. 1. Evolutionary Biology
   2. Genetics and Genomics

   Single nucleus sequencing reveals evidence of inter-nucleus recombination in arbuscular mycorrhizal fungi

   Eric CH Chen et al.

   Arbuscular mycorrhizal fungi generate nuclear diversity in the dikaryotic life-stage stage via inter-nucleus recombination.
4. 1. Genetics and Genomics

   Spliceosome factors target timeless (tim) mRNA to control clock protein accumulation and circadian behavior in Drosophila

   Iryna Shakhmantsir et al.

   Alternative splicing provides a mechanism to maintain oscillations of the circadian clock.
5. 1. Computational and Systems Biology
   2. Genetics and Genomics

   A new experimental platform facilitates assessment of the transcriptional and chromatin landscapes of aging yeast

   David G Hendrickson et al.

   A new technology for obtaining aged yeast cells helps reveal a striking connection between aging, slow growth, and stress.
6. 1. Computational and Systems Biology
   2. Genetics and Genomics

   Life Expectancy: Advancing the aging biology toolkit

   Troy K Coody, Adam L Hughes

   A new device for isolating large quantities of old yeast cells expands the experimental boundaries of aging research.
7. 1. Genetics and Genomics

   Natural variation in sugar tolerance associates with changes in signaling and mitochondrial ribosome biogenesis

   Richard G Melvin et al.
8. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   The Aquilegia genome provides insight into adaptive radiation and reveals an extraordinarily polymorphic chromosome with a unique history

   Danièle L Filiault et al.

   The evolution columbine genus involved frequent mixing between incipient species, and one chromosome appears to have taken its own path.
9. 1. Cancer Biology
   2. Genetics and Genomics

   Targets and genomic constraints of ectopic Dnmt3b expression

   Yingying Zhang et al.

   Ectopic expression of Dnmt3b leads to wide-spread CpG island hypermethylation that is largely defined by chromatin state and has some distinct features when compared to the cancer methylome.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    ASH1-catalyzed H3K36 methylation drives gene repression and marks H3K27me2/3-competent chromatin

    Vincent T Bicocca et al.

    While SET-2 methylates histone H3K36 during transcription, ASH1 methylates this residue in repressed regions, is important for silencing, and can both positively and negatively influence methylation of histone H3K27.