Editors for Medicine

We aim to publish significant translational research and clinical studies focused on improving human health. Our interests include, but are not limited to, the etiology, pathophysiology, diagnosis, genetics, prevention, and treatment of human disorders, as well as the biological, environmental and socioeconomic determinants of health which lead to changes in medical practice, population health and health policy. Read the latest research in this subject area.

Senior editors

  1. Matthias Barton

    University of Zurich, Switzerland

    Matthias Barton, MD, is a Professor of Cardiology at the University of Zurich. His clinical and investigative focus are general cardiology and preventive medicine, with a particular interest in coronary artery disease and myocardial infarction. His work explores mechanisms of atherosclerosis, heart disease in women, and vascular factors contributing to cardiovascular health and disease.

    Expertise
    Medicine
    Research focus
    cardiovascular medicine
    coronary artery disease
    vascular biology
    heart disease in women
    molecular medicine
    Competing interests statement
    Matthias Barton has received funding from the Swiss National Science Foundation and is on the editorial boards of the American Journal of Cardiovascular Disease, the American Journal of Physiology Regulatory Integrative & Comparative Physiology, Endocrine and Metabolic Science, Experimental Biology and Medicine, Arteriosclerosis, Thrombosis and Vascular Biology and Hypertension, official journals of the American Heart Association. He has been an elected ordinary member of the Academy of Europe (Academia Europaea) since 2017.
  2. Christian Büchel

    University Medical Center Hamburg-Eppendorf, Germany

    Christian Büchel is a member of the Hamburg Center for Neuroscience in Hamburg, where he is also the Director of the Department for Systems Neuroscience at Hamburg University Medical Center. He holds an Affiliate Professor appointment in the Psychology department at the University of Hamburg. After Medical School at the University of Heidelberg, he performed postdoctoral research with Karl Friston as a Wellcome Research Fellow at the Wellcome Department of Imaging Neuroscience at UCL in London with a focus on effective connectivity.

    Establishing his lab in Hamburg, he focused on the cognitive neuroscience of pain and motivation and initially studied decision making with an emphasis on delay discounting. In a parallel stream of projects he observed that the pain modulation underlying placebo analgesia can already be observed at the spinal cord level, a finding which he later also established for nocebo hyperalgesia. He is part of the IMAGEN study and during his time at Stanford he identified hypoactivation of reward circuits as a potential risk factor for addiction.

    He is a member of the Academy of Science in Hamburg and was awarded the Jung Award for Medicine, the Gottfried Wilhelm Leibniz-Preis by the German Research Foundation, and the Wiley Young Investigator Award of the Organization for Human Brain Mapping for recognition of his work in cognitive neuroscience.

    Expertise
    Neuroscience
    Medicine
    Research focus
    cognitive neuroscience
    pain modulation
    decision-making
    fear
    anxiety
    addiction
    Experimental organism
    human
    Competing interests statement
    Christian Büchel has received research grants from the European Research Council, Deutsche Forschungsgemeinschaft and Bundesministerium für Bildung und Forschung. He serves on the board of reviewing editors of Science magazine. He serves on the Swiss National Research Council, the Scientific Advisory Board of the ICM in Paris and the Center for Behavioral Brain Sciences, Magdeburg, Germany.
  3. Miles P Davenport

    University of New South Wales, Australia

    Miles Davenport is Professor of Medicine and Head of the Infection Analytics Program at the Kirby Institute for Infection and Immunity at UNSW Sydney. He graduated in medicine from the University of Sydney and completed his DPhil at the University of Oxford in immunology before retraining in mathematical biology. He leads a team of applied mathematicians who use statistical analysis and modelling to understand host-pathogen interactions in infection and immunity. This involves collaboration with a wide variety of experimental and clinical scientists both in Australian and internationally. Major areas of investigation include understanding HIV latency, malaria immunity and treatment, and neonatal immune development. He is a past-President of the Australasian Society for Immunology and is supported by an NHMRC (Australia) Investigator grant.

    Expertise
    Immunology and Inflammation
    Microbiology and Infectious Disease
    Epidemiology and Global Health
    Medicine
    Research focus
    virology
    immunity
    vaccines
    HIV/AIDS
    mathematical modelling
    host-pathogen interactions
    biostatistics
    Competing interests statement
    Miles Davenport receives funding from the National Health and Medical Research Council (Australia), the Australian Research Council, and the National Institutes of Health (USA). He is an Associate Editor at PLoS Computational Biology and on the Editorial Board of Immunology and Cell Biology.
  4. Betty Diamond

    The Feinstein Institute for Medical Research, United States

    Betty Diamond received an MD from Harvard Medical School. She performed a residency in Internal Medicine at Columbia Presbyterian Medical Center, and then a post-doctoral fellowship in Immunology with Dr Matthew Scharff at the Albert Einstein College of Medicine. She is currently Director of the Institute of Molecular Medicine at the Feinstein Institute for Medical Research.

    Dr Diamond’s research has focused on the induction and pathogenicity of anti-DNA antibodies in Systemic Lupus Erythematosus. She showed that somatic mutation of immunoglobulin genes can generate autoantibodies in mice and humans, making the germinal center a focus in disease pathogenesis. Her laboratory has also demonstrated that a subset of anti-DNA antibodies cross-reacts with the NMDA receptor and showed that autoantibodies can cause aspects of neuropsychiatric lupus, creating a paradigm for antibody-mediated changes in brain function in many conditions. Most recently, she has developed a research program on the immunomodulatory functions of C1q.

    She received the Outstanding Investigator Award of the ACR in 2001, the Lee Howley Award from the Arthritis Foundation in 2002, and the Recognition Award from the National Association of MD-PhD Programs in 2004 and the AAI Distinguished Fellow Award in 2019. In 2006, she was elected to the Institute of Medicine and became a fellow of the AAAS. She has served on the Scientific Council of NIAMS and the Board of Directors of the American College of Rheumatology. She is a past President of the American Association of Immunologists.

    Expertise
    Medicine
    Immunology and Inflammation
    Research focus
    B cells
    systemic lupus
    neuropsychiatric lupus
    autoantibodies
    autoimmunity
    Experimental organism
    human
    mouse
    Competing interests statement
    Betty Diamond receives funding from the NIH, LuCIN (Lupus Clinical Investigators Network), Lupus Research Alliance, DOD Lupus and Leidos Biomedical Research, Inc.. She is the Chief Editor at Molecular Medicine and a Deputy Editor for Frontiers in Immunology.
  5. Wafik S El-Deiry

    Brown University, United States

    Wafik El-Deiry, MD, PhD, FACP is Associate Dean for Oncologic Sciences at the Warren Alpert Medical School, Director, Cancer Center at Brown University, and Director of the Joint Program in Cancer Biology at Brown and Lifespan. He is a Professor of Pathology and Laboratory Medicine, Professor of Medical Science, and Mencoff Family University Professor at Brown. He sees patients in his weekly clinic at Rhode Island Hospital focused on care of patients with colorectal cancer and participates in clinical trials based on his laboratory’s research on novel therapeutics. He previously served as Deputy Director for Translational Research, co-Leader of the Molecular Therapeutics Program, Professor of Oncology, and the William Wikoff Smith Endowed Chair in Cancer Research at Fox Chase Cancer Center. From 2010 through 2014 Dr El-Deiry was the Rose Dunlap Professor of Medicine and Chief of Hematology-Oncology at Penn State. In 2009, El-Deiry became an American Cancer Society Research Professor. He was previously a tenured Professor of Medicine (Hematology-Oncology), Genetics, and Pharmacology at University of Pennsylvania, co-Leader of the Radiobiology and Imaging Program at the Abramson Cancer Center and Associate Director for Physician-Scientist Training in Hematology-Oncology when he left Penn in 2010. He earned MD/PhD degrees from University of Miami School of Medicine and completed internal medicine residency and medical oncology fellowship at the Johns Hopkins Hospital and the Johns Hopkins Oncology Center. As a practicing academic Oncologist, his scientific interest and expertise is in cell death, drug resistance in cancer and drug discovery and development. El-Deiry founded two companies, Oncoceutics, Inc. and p53-Therapeutics, Inc.

    El-Deiry discovered p21(WAF1) as a p53 target gene, universal cell cycle inhibitor, and tumor suppressor gene that for the first time explained the mammalian cell stress response. He discovered TRAIL receptor DR5 and its regulation by p53. TRAIL is part of the host immune system that suppresses cancer and its metastases. His lab created a knock-out mouse for TRAIL receptor DR5 and this mouse is tumor prone and develops an inflammatory syndrome in the lungs and gut after sub-lethal irradiation. He identified c-Myc as a major determinant of TRAIL sensitivity and demonstrated synergy between TRAIL therapy and multi-kinase inhibitor sorafenib. Building on his prior accomplishments, El-Deiry discovered ONC201/TIC10 as a first-in-class TRAIL pathway inducer that is orally bioavailable and crosses the blood-brain barrier to treat brain tumors. TRAIL and Foxo3a are required for the anti-tumor effect of ONC201 through dual blockade of ERK and Akt kinases that promotes the nuclear translocation of the Foxo3a transcription factor which directly regulates the TRAIL gene. Data from El-Deiry’s lab identified that ONC201 induces TRAIL receptor DR5 through an integrated stress response involving ATF4 and CHOP transcription factors. Patients with among the most aggressive gliomas (H3K27M mutant DIPG) have had exceptional responses to ONC201.

    As a physician-scientist, Dr El-Deiry has worked to bring new discoveries to the clinic. He is committed in the next phase of his career to unraveling the mechanisms involved in p53 pathway restoration by candidate therapeutics his lab has discovered. This is exciting as he is defining a novel class of anti-cancer drugs with p53 pathway restoration and S-phase checkpoint targeting and recognizing ATF4 as a major transcription factor mechanism for p53 pathway restoration in p53-null or p53 mutant tumor cells. He is establishing transcriptomic and proteomic data sets with chemotherapy that acts through p53, and with novel small molecules that restore the p53 pathway in p53-deficient or mutant p53 expressing cells. He is exploiting medicinal chemistry and organoid technologies to perform his translational science that is leading to clinical trials some of which he leads. Dr El-Deiry conducts basic and translational clinical oncology therapeutics research through funded NIH grants, Foundations and industry. He is a member of the ASCI, AAP, Past President of the Interurban Clinical Club, previous Chair of ASCO’s Tumor Biology Track, and past Chair of an NIH Study Section on Cancer Therapeutics. Dr El-Deiry has trained many students and post-doctoral fellows, physician-scientists, and continues to mentor junior scientists and faculty in basic and translational cancer research.

    Expertise
    Medicine
    Cancer Biology
    Research focus
    cancer
    tumor suppressor genes
    colorectal cancer
    p53 pathway
    cell death
    medical oncology
    drug development
    drug discovery
    p21(WAF1)
    ONC201/TIC10
    physician-scientist issues
    Experimental organism
    human
    mouse
    Competing interests statement
    Dr El-Deiry receives funding from the NIH/NCI, the Warren Alpert Foundation, and D&D Pharmatech. He is a Specialty Chief Editor for the Cancer Molecular Targets and Therapeutics Section of Frontiers in Oncology. He is also a Section Editor for Molecular Oncology and HemOnc Today. Dr El-Deiry is the scientific founder and shareholder of Oncoceutics, Inc.
    and p53-Therapeutics, Inc.
  6. Eduardo Franco

    McGill University, Canada

    Eduardo Franco is Professor and Chairman, Department of Oncology, and Director, Division of Cancer Epidemiology, McGill University, Montreal. He holds BSc (1975) and Licentiate (1976) degrees in biology from Universidade de Campinas, Brazil, and master's (MPH) and doctoral (DrPH) degrees in public health microbiology from the University of North Carolina at Chapel Hill (1981-84). He was a Guest Researcher at the US Centers for Disease Control in Atlanta (1980-81 and 1983-84), and a post-doctoral fellow in cancer epidemiology during 1984 at the International Agency for Research on Cancer in Lyon, France, at the US National Cancer Institute (NCI) in Bethesda, and at Louisiana State University, in New Orleans. Since 1985, he has conducted epidemiologic research on the causes of cancer and on the means to prevent it or to improve patient survival. He is mostly known for his contributions to our understanding of human papillomavirus infection as the cause of cervical cancer and using this knowledge to prevent this cancer via vaccination and improved screening strategies. He received the Canadian Cancer Research Alliance’s Distinguished Service to Cancer Research Award, Lifetime Achievement Awards from the American Society for Colposcopy and Cervical Pathology and from the International Papillomavirus Society, the Women in US Government’s Leadership Award, the Canadian Cancer Society’s Warwick Prize, the Geoffrey Howe Outstanding Contribution Award from the Canadian Society for Epidemiology and Biostatistics, the University of British Columbia’s Chew Wei Memorial Prize in Cancer Research, and the McLaughlin-Gallie Award from the Royal College of Physicians of Canada. He has mentored 115 graduate students and post-doctoral fellows, and 30 undergraduate trainees. He is Officer of the Order of Canada and Fellow of the Royal Society of Canada and of the Canadian Academy of Health Sciences. Heholds an honorary doctorate from Universidade Fernando Pessoa, Porto, Portugal.

    Expertise
    Cancer Biology
    Epidemiology and Global Health
    Medicine
    Research focus
    cancer epidemiology
    cancer prevention
    human papillomavirus
    cancer screening
    Experimental organism
    human
    Competing interests statement
    Entire research program funded by the Medical Research Council of Canada (until 1999), Canadian Institutes of Health Research (CIHR) (1999-present), National Institutes of Health, Canadian Cancer Society, and Cancer Research Society. He has received salary awards from the Fonds de Recherche Quebec Santé and CIHR. He holds a James McGill Professorship and the Minda de Gunzburg Endowed Chair at McGill University. He serves as Editor-in-Chief for Preventive Medicine and Preventive Medicine Reports and serves on the editorial boards of Cancer Epidemiology, Biomarkers & Prevention, International Journal of Cancer, Papillomavirus Research, and Salud Publica de Mexico. He has served as occasional consultant to companies involved with HPV vaccination (Merck and GSK) and HPV diagnostics (Roche, Abbott, Qiagen, and BD).
  7. Wendy S Garrett

    Wendy S Garrett

    Harvard T.H. Chan School of Public Health, United States

    Wendy Garrett is a Professor of Immunology and Infectious Diseases at the Harvard T. H. Chan School of Public Health, co-Director of the Harvard Chan Center for the Microbiome in Public Health, and an Associate Member of the Broad Institute. Her work explores host-microbiota interactions underlying mucosal immune homeostasis, gastrointestinal inflammatory disorders, and cancer. She graduated from the Yale College; received her MD PhD from Yale University and completed post-graduate training at Harvard.

    Expertise
    Immunology and Inflammation
    Microbiology and Infectious Disease
    Medicine
    Research focus
    host-microbiota interactions
    microbiome
    mucosal immunology
    Competing interests statement
    Wendy Garrett serves on advisory boards of Evelo Biosciences, Kintai Therapeutics, and Leap Therapeutics. She is a member of the Cell Reports and Journal of Clinical Microbiology editorial boards.
  8. Diane M Harper

    University of Michigan, United States

    Diane M Harper, MD, MPH, MS, completed her undergraduate and graduate degrees at the Massachusetts Institute of Technology in Cambridge, Massachusetts, in the fields of Chemical Engineering and Polymerics. She received her medical and public health degrees from the University of Kansas in Kansas City, where she also did residencies in Gynecology/Obstetrics and Family Medicine. Dr Harper has spent the majority of her professional career at Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, as clinician, teacher and researcher in the Departments of Obstetrics and Gynecology, Community and Family Medicine and Women’s and Gender Studies, including improving life for LGBTQ.

    She has received the Society of Teachers of Family Medicine (STFM) Excellence in Education Award and the Curtis Hames Research Award honoring her for changing medical care for women through evidence based research. She served as the Chair of Family and Geriatric Medicine at the University of Louisville during which time she also served on the United States Preventive Services Task Force.

    She currently is a tenured Professor at the University of Michigan, serving as the Director for Research Management within the Michigan Institute of Clinical and Health Research, one of 50 Clinical and Translational Science Award Research Hubs across the United States. To date she has over 250 peer reviewed publications with over 27,000 citations, and over 40,000 downloads of her seminal review of HPV vaccines.

    While at Dartmouth she developed and directed the Gynecologic Cancer Prevention Research Group based at the Norris Cotton Cancer Center in which research on all aspects of HPV associated diseases, specifically cervical cancer prevention was conducted. She is an internationally recognized expert on Human Papillomavirus, the cause of cervical cancer, and its prophylactic and therapeutic vaccines. She has published the sentinel clinical research on HPV vaccines and lectured internationally in over 100 countries. She has served on NCI research committees, European research study sections, addressed the Council on Foreign Affairs, and served as a technical advisor to the World Health Organization. Dr Harper has been honored as one of the top clinicians in her field in the US, and Family Physician of the Year in New Hampshire in 2006.

    Expertise
    Medicine
    Epidemiology and Global Health
    Microbiology and Infectious Disease
    Immunology and Inflammation
    Research focus
    HPV associated diseases
    primary care
    women's health
    cancer precursor detection
    health behaviours
    epidemiology
    cancer screening
    Experimental organism
    human
    Competing interests statement
    Diane Harper has received funding from NCI, NCATS, NHLBI, CDC, multiple national philanthropic organizations, including the American Cancer Society, The Robert Wood Johnson Foundation, and the Susan G Komen Foundation, in addition to state and local funding agencies and collaborations with industry. She serves in editorship capacities on boards including the Annals of Family Medicine, Preventive Medicine Reports, PLoS ONE, and Gynecologic Oncology. She is a peer reviewer for The Lancet, The New England Journal of Medicine, JAMA, among other journals.
  9. Carlos Isales

    Medical College of Georgia at Augusta University, United States

    Carlos Isales is from San Juan, Puerto Rico, where he graduated from the University of Puerto Rico School of Medicine and did his residency in Internal Medicine at the San Juan Veterans Administration Hospital. He completed a fellowship in Endocrinology and Metabolism at Yale University School of Medicine working in a laboratory under Dr Howard Rasmussen. In 1993, he moved to the Medical College of Georgia in Augusta, GA to help establish the Institute of Molecular Medicine and Genetics. His work has focused on defining the impact of nutrients on bone metabolism and loss of nutrient sensing with aging leading to both bone and muscle loss. His group was among the first to characterize an entero-osseous axis linking incretin hormones and bone turnover. Current work is focused on defining the impact of oxidation of aromatic amino acids and downstream metabolites such as tryptophan-kynurenine on stem cell proliferation and differentiation and resultant age-related osteoporosis. He is currently Chief of the Division of Endocrinology and Metabolism at Augusta University, Regents’ Professor and J. Harold Harrison Distinguished University Chair in Healthy Aging. He is also the Clinical Director of the newly established Center for Healthy Aging. His research is funded by the National Institutes of Aging. He is also passionate about mentoring the next generation of scientists and is MPI on a training award from the National Institutes on Aging.

    Expertise
    Medicine
    Research focus
    aging
    stem cells
    epigenetics
    metabolic bone disease
    nutrition
    amino acid metabolism
    tryptophan metabolism
    Experimental organism
    human
    mouse
    Competing interests statement
    Carlos Isales is currently funded by the National Institute on Aging. He is co-founder of Gerologix, a company focused on developing countermeasures to musculoskeletal aging. He is currently Academic Editor for PLOS ONE and JBMR Plus.
  10. Y M Dennis Lo

    The Chinese University of Hong Kong, Hong Kong SAR China

    Dennis Lo is the Li Ka Shing Professor of Medicine and Director of the Li Ka Shing Institute of Health Sciences at The Chinese University of Hong Kong. He received his BA (Hons) from the University of Cambridge and his Doctor of Medicine and Doctor of Philosophy degrees from the University of Oxford. He discovered the presence of cell-free fetal DNA in maternal plasma in 1997. He has since translated this finding into a platform for noninvasive prenatal testing (NIPT). He has also made concurrent discoveries and inventions in the liquid biopsies of cancer. In recognition of his work, he has been elected as a Fellow of the Royal Society (UK), Foreign Associate of the US National Academy of Sciences, Fellow of the World Academy of Sciences and a founding member of the Hong Kong Academy of Sciences. He is a recipient of the Breakthrough Prize in Life Sciences (2021).

    Expertise
    Medicine
    Genetics and Genomics
    Research focus
    molecular diagnostics
    prenatal diagnosis
    biomarkers in oncology
    clinical genomics
    noninvasive prenatal testing
    cancer screening with liquid biopsy
    Experimental organism
    human
    mouse
    Competing interests statement
    Research funding from the Hong Kong Research Grants Council, Innovation and Technology Commission and Li Ka Shing Foundation. Trustee of the Croucher Foundation. Commercial relationships including licensing, equity or consultancy: Grail, Illumina, Sequenom, Xcelom, DRA, Take2 and Decheng Capital. Associate editorship of journals: Clinical Chemistry, npj Genomic Medicine. Memberships of journal editorial boards: Journal of Pathology, Philosophical Transactions of the Royal Society B, Journal of Genomes and Exomes, Disease Markers and Marrow.
  11. Jos WM van der Meer

    Radboud University Medical Centre, Netherlands

    Jos WM van der Meer is emeritus Professor of Medicine at Radboud University Nijmegen, The Netherlands. Between 1992 and 2012 he was head of the Department of internal medicine at the Radboud University Medical Centre. His major areas of expertise are host defence against infection, trained immunity, autoinflammation, immunodeficiency and antimicrobial policy.

    Expertise
    Medicine
    Microbiology and Infectious Disease
    Research focus
    infectious disease and host defense
    innate immunity
    trained immunity
    immunodeficiency
    autoinflammatory diseases
    chronic fatigue syndrome
    Experimental organism
    human
    mouse
    Competing interests statement
    Jos WM van der Meer is a member of the Royal Netherlands Academy of Arts and Sciences (KNAW), for which he served as a vice-president from 2005 to 2011. He is a member of Academia Europaea and he is past-president of EASAC, the European Academies Science Advisory Council. He is an honorary Fellow of the Royal College of Physicians in London and in Edinburgh and a fellow of the Infectious Diseases Society of America and of the European Society of Clinical Microbiology and Infectious diseases. He is a member of the Dutch National Board for Research Integrity LOWI. He received a number of prices and awards, such as the Gold Hijmans van den Bergh medal. He was awarded knighthood in the order of the Netherlands Lion in 2003.
  12. Gary Westbrook

    Vollum Institute, United States

    Gary Westbrook is a Senior Scientist at the Vollum Institute and Rocky and Julie Dixon Professor of Neurology at Oregon Health & Science University. Dr. Westbrook is a member of the National Academy of Medicine (formerly Institute of Medicine), the American Academy of Arts and Sciences, and past editor-in-chief of the Journal of Neuroscience. He has received Javits and Merit awards from NIH for his research as well as an International Cooperation Award from the Max Planck Society. Dr. Westbrook received his medical training and did graduate study in Biomedical Engineering at Case Western Reserve University, followed by residencies in Internal Medicine and Neurology, and basic neuroscience research at the National Institutes of Health in Bethesda. Earlier work in his lab was mostly directed at the level of receptors, particularly N-methyl-D-aspartate (NMDA) receptors, and the function of single synapses. The emphasis has now largely shifted to studies of small networks (microcircuits) in the hippocampus. Dr. Westbrook maintains interests in clinical neurology, particularly epilepsy, as well as graduate research training. He was co-Director of the Vollum Institute (2005-2015) and director of the Neuroscience Graduate Program at Vollum/OHSU (2008-2018).

    Expertise
    Neuroscience
    Medicine
    Research focus
    synaptic transmission
    synaptic plasticity
    ligand-gated ion channels
    hippocampus
    olfactory bulb
    epilepsy
    in vitro physiology
    activity-dependent gene expression
    Experimental organism
    mouse
    Competing interests statement
    Gary Westbrook is employed by Oregon Health and Science University. He receives research and training funding from the National Institutes of Health and the Ellison Medical Foundation. He is a member of the National Academy of Medicine (formerly Institute of Medicine) and the American Academy of Arts and Sciences. He serves on Scientific Advisory Boards for Max Planck Institutes in Göttingen (MPIEM) and Florida (MPFI), the Myelin Repair Foundation, and on study sections for the National Institutes of Health. He is currently a member of editorial boards for Physiological Reviews and Philosophical Transactions of the Royal Society B.
  13. Richard M White

    Memorial Sloan Kettering Cancer Center, United States

    Richard White, M.D., Ph.D, is a physician-scientist at the Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College. He is interested in basic mechanisms underlying metastasis, using the zebrafish as a model system. His work has established numerous techniques for cancer modeling and high-resolution imaging in the fish. Using these tools, the lab is focused on the cross-talk between tumor cells and the microenvironment, and how this interplay influences metastatic success. His work has revealed novel interactions between melanoma cells and adipocytes in the microenvironment, and how neural crest programs play roles in melanoma progression. He has been awarded the NIH Director’s New Innovator Award, the Pershing Square Foundation Award, and the Mark Foundation ASPIRE award.

    Expertise
    Cancer Biology
    Medicine
    Research focus
    metastasis
    melanocyte development
    neural crest
    melanoma
    adipocytes
    microenvironment
    melanocytes
    Experimental organism
    zebrafish
    Competing interests statement
    Richard White receives funding from the National Institutes of Health, the Pershing Square Sohn Foundation, the Mark Foundation, the Melanoma Research Alliance, the American Cancer Society and the Harry J. Lloyd Foundation. He receives consulting fees from N-of-One, Inc.
  14. Mone Zaidi

    Icahn School of Medicine at Mount Sinai, United States

    Mone Zaidi graduated in medicine from King George’s Medical College, India, and trained clinically at the Hammersmith Hospital, London, under the tutelage of Iain MacIntyre, FRS. After obtaining a PhD and MD from the University of London, Dr Zaidi held appointments as Lecturer at the Royal Postgraduate Medical School and Senior Lecturer and Honorary Consultant at St. George’s Hospital Medical School for over 8 years. In 1999, he moved to Mount Sinai School of Medicine in New York as Professor of Medicine and Founding Director of The Mount Sinai Bone Program. Zaidi has discovered mechanisms of skeletal homeostasis in health and its dysregulation in common and rare diseases. These studies, spanning over 30 years, included the first description of calcium sensing in the osteoclast and the discovery that locally released nitric oxide acts to suppress bone removal. In 2003, his group published evidence for a pituitary–bone axis of medical significance, in which pituitary hormones affect the skeleton directly. More recently, he found that inhibiting FSH not only increased bone mass, but also reduced body fat and increased thermogenesis – in essence, laying the firm foundation for his new humanized monoclonal FSH antibody to treat both osteoporosis and obesity. This corpus of work was selected by Nature Medicine as one of eight “Notable Advances” in biomedicine for 2017. Zaidi’s research was funded by the Medical Research Council of the UK, and since 1997, by the US National Institutes of Health. He is an elected member of the American Society for Clinical Investigation, Association of American Physicians, the Interurban Clinical Club (established by Sir William Osler in 1905) of which he was President, the Practitioners’ Society of New York (the oldest medical society in the US), and the Association of Professors of Medicine. Zaidi was made Master of the American College of Physicians, received the Harrington Scholar-Innovator Award, was elected as Fellow of the American Association of Advancement of Science, and is recipient of three honorary doctorates.

    Expertise
    Medicine
    Research focus
    osteoporosis
    obesity
    bone mass
    metabolism
    adipose tissue
    endocrine physiology
    pituitary hormones
    FSH
    Competing interests statement
    Mone Zaidi is currently funded by the National Institute on Aging and the National Institute of Diabetes, Digestive and Kidney Diseases of the NIH. He is inventor on several patents in relation to his work on FSH, bone and body composition. He is currently Consulting Editor for the Journal of Clinical Investigation, Editor of a series – Marrow – of the Annals of the New York Academy of Sciences, and Editor-in-chief of the Encyclopedia of Bone Biology, published by Elsevier as their Major Reference Works.
  15. Huda Zoghbi

    Huda Zoghbi

    Baylor College of Medicine and Texas Children's Hospital, United States, United States

    Huda Zoghbi is Professor of Pediatrics, Neurology, Molecular and Human Genetics, and Neuroscience at Baylor College of Medicine, Houston, Texas. She is also an Investigator with the Howard Hughes Medical Institute and Director of the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital. Her research focuses on understanding normal brain development and on elucidating the pathogenesis of several neurological disorders including the autism spectrum disorder, Rett syndrome, and late-onset neurodegenerative diseases.

    Expertise
    Neuroscience
    Genetics and Genomics
    Medicine
    Research focus
    neurobiology of disease
    neurodegeneration
    autism
    ataxia
    Experimental organism
    human
    mouse
    Competing interests statement
    Huda Zoghbi is actively receiving funds from the Howard Hughes Medical Institute, the National Institutes of Health, Rett Syndrome Research Trust, International Rett syndrome Foundation (and she is a member of advisory panels for all four organizations), Baylor College of Medicine, and Texas Children’s Hospital. She is Editor-in-chief of Annual Reviews of Neuroscience and a member of the editorial team of Cell and Neuron. She is immediate past President of the McKnight Neuroscience Fund and a member of the following Scientific Advisory Panels: Shaw Prize Jury, Breakthrough Prize Jury, and Vilcek Prize Jury; and a member of the Scientific Advisory Board of Denali Therapeutics and The Column Group. She is also a member of Regeneron’s Board.

Reviewing editors

  1. Jonathan Abraham

    Harvard Medical School, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Microbiology and Infectious Disease
    Medicine
    Research focus
    emerging viruses
    antibody neutralisation
    viral entry
    viral replication
    x-ray crystallography
    cryo-EM
  2. Cheryl Ackert-Bicknell

    University of Colorado, United States

    Expertise
    Medicine
    Genetics and Genomics
    Research focus
    bone biology
    genetics
    musculoskeletal
    aging
  3. Anurag Agrawal

    CSIR Institute of Genomics and Integrative Biology, India

    Expertise
    Medicine
    Research focus
    asthma
    respiratory diseases
    Experimental organism
    human
    mouse
  4. Hossein Ardehali

    Northwestern University, United States

    Expertise
    Medicine
    Biochemistry and Chemical Biology
    Research focus
    mitochondria
    iron
    glucose metabolism
    mRNA-binding proteins
    hexokinases
    metabolism
    cardiac biology
  5. Annelien Bredenoord

    University Medical Centre Utrecht, Netherlands

    Expertise
    Medicine
    Research focus
    medical ethics
    bioethics
    ethics
    genome editing
    technologies
    innovation
    biobanking
    stem cells
    big data
    DNA sequencing
  6. Xuetao Cao

    Zhejiang University School of Medicine, China

    Expertise
    Cancer Biology
    Immunology and Inflammation
    Medicine
    Research focus
    immunology of APCs
    TLR signalling and immune regulation
    cancer immunotherapy and gene therapy
  7. Jean-Laurent Casanova

    The Rockefeller University, United States

    Expertise
    Genetics and Genomics
    Microbiology and Infectious Disease
    Immunology and Inflammation
    Medicine
    Research focus
    human genetics
    immunology
    infectious diseases
    primary immunodeficiency
    inborn errors of immunity
    Experimental organism
    human
  8. Howard Y Chang

    Stanford University, United States

    Expertise
    Medicine
    Chromosomes and Gene Expression
    Genetics and Genomics
    Research focus
    cancer
    immunotherapy
    RNA
    genomics
    epigenomics
    dermatology
    Experimental organism
    human
    mouse
  9. Yali Cong

    Peking University Health Science Center, China

    Expertise
    Medicine
    Research focus
    medical ethics
    bioethics
  10. Alex R Cook

    National University of Singapore, Singapore

    Expertise
    Epidemiology and Global Health
    Microbiology and Infectious Disease
    Medicine
    Research focus
    infectious disease epidemiology
    mathematical modelling
    biostatistics
    health policy
  11. Seth J Corey

    Cleveland Clinic, United States

    Expertise
    Cancer Biology
    Medicine
    Research focus
    myeloid malignancies
    inherited or acquired bone marrow failure
    neutrophils
    platelets zebrafish
    cancer evolution
    proteostasis
  12. Ralph J DeBerardinis

    University of Texas Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Cell Biology
    Medicine
    Research focus
    metabolism
    cancer
    genetics
    medicine
    pediatrics
    genomics
    mitochondria
    Experimental organism
    human
    mouse
  13. Anna Mae Diehl

    Duke University School of Medicine, United States

    Expertise
    Medicine
    Research focus
    gastroenterology
    hepatology
  14. Ana Domingos

    University of Oxford, United Kingdom

    Expertise
    Medicine
    Neuroscience
    Research focus
    metabolism
    obesity
    neuroimmunity
    autonomic nervous system
    eating behaviour
    inflammation
  15. Noriaki Emoto

    Kobe Pharmaceutical University, Japan

    Expertise
    Medicine
    Research focus
    cardiology
    pulmonary hypertension
    endothelin
    pharmacology
    vascular biology
  16. Jonathan Flint

    University of California, Los Angeles, United States

    Expertise
    Genetics and Genomics
    Medicine
    Research focus
    genetics
    genomics
    psychiatric disorders
  17. Gregory G Germino

    National Institute of Diabetes and Digestive and Kidney Diseases, United States

    Expertise
    Medicine
    Research focus
    nephrology
    genetic renal disease
    polycystic kidney disease
    ciliopathies
  18. Evangelos J Giamarellos-Bourboulis

    Attikon University Hospital, Greece

    Expertise
    Immunology and Inflammation
    Microbiology and Infectious Disease
    Genetics and Genomics
    Medicine
    Research focus
    sepsis
    hidradenitis suppurativa
    pathogenesis of infection
    biomarkers
  19. David Ginsburg

    University of Michigan, United States

    Expertise
    Medicine
    Genetics and Genomics
    Research focus
    hemostasis
    thrombosis
    human genetics
    mouse genetics
    endothelial cells
    cargo receptor
    secretion
    Experimental organism
    human
    mouse
    zebrafish
  20. Joseph G Gleeson

    The Rockefeller University, United States

    Expertise
    Medicine
    Neuroscience
    Developmental Biology
    Research focus
    neurodevelopmental disease
    brain development
    neurogenetics
    autism
    epilepsy
    intellectual disability
    organoid
    stem cells
    genomics
    bioinformatics
    Experimental organism
    human
    mouse
  21. Michael R Green

    University of Massachusetts Medical School, United States

    Expertise
    Cancer Biology
    Chromosomes and Gene Expression
    Medicine
    Research focus
    transcription
    pre-mRNA splicing
    cancer molecular biology
    oncology
    genetics
    functional genomics
    Experimental organism
    human
    mouse
    S. cerevisiae
  22. Timothy D Griffiths

    Newcastle University, United Kingdom

    Expertise
    Neuroscience
    Medicine
    Research focus
    auditory
    cognition
    neurology
    imaging
    Experimental organism
    human
    macaque
  23. William C Hahn

    Dana-Farber Cancer Institute, United States

    Expertise
    Cancer Biology
    Genetics and Genomics
    Medicine
    Research focus
    cancer
    transformation
    functional genomics
    RAS
    YAP1
    Experimental organism
    human
  24. Matthew G. Vander Heiden

    Massachusetts Institute of Technology, United States

    Expertise
    Cancer Biology
    Medicine
    Research focus
    cancer biology
    biochemistry
    metabolism
    tumor microenvironment
    redox biology
    Experimental organism
    mouse
    human
  25. Christopher L-H Huang

    University of Cambridge, United Kingdom

    Expertise
    Medicine
    Research focus
    cardiac arrhythmias
    atrial fibrillation
    skeletal muscle
    electrophysiology
    ion channels
    action potential propagation
    genetically modified mice
    patch clamping
    Experimental organism
    mouse
  26. Edward D Janus

    University of Melbourne, Australia

    Expertise
    Epidemiology and Global Health
    Medicine
    Research focus
    cardiovascular disease
    diabetes
    prevention
    chronic diseases
    clinical guidelines
  27. Prabhat Jha

    Saint Michael's Hospital, Canada

    Expertise
    Epidemiology and Global Health
    Microbiology and Infectious Disease
    Medicine
    Research focus
    epidemiology
    global health
    infectious disease and population dynamics
    randomized controlled trials
  28. Simon C Johnson

    Seattle Children's Research Institute, United States

    Expertise
    Cell Biology
    Medicine
    Developmental Biology
    Neuroscience
    Research focus
    mitochondria
    neurodegenerative disease
    aging
    pediatric disease
    genetic disease
    mTOR
    cell culture
    Experimental organism
    mouse
    C. elegans
  29. Eunjoon Kim

    Korea Advanced Institute of Science and Technology, South Korea

    Expertise
    Medicine
    Neuroscience
    Research focus
    synapse adhesion and synapse development
    synaptic transmission and plasticity
    neurodevelopmental and neuropsychiatric disorders
    autism spectrum disorders
    intellectual disability
    Experimental organism
    mouse
    rat
  30. Melanie Königshoff

    University of Colorado, United States

    Expertise
    Stem Cells and Regenerative Medicine
    Medicine
    Cell Biology
    Research focus
    lung regeneration
    wnt signaling
    pulmonary fibrosis
    chronic obstructive pulmonary disease
    epithelial cell biology
    Experimental organism
    human
    mouse
  31. Dan Larhammar

    Uppsala University, Sweden

    Expertise
    Medicine
    Evolutionary Biology
    Neuroscience
    Research focus
    evolution
    gene/genome duplications
    cellular and molecular neuroscience
    G protein-coupled receptors (GPCR)
    neuropeptides
    endocrine peptides
    hypothalamus
    phototransduction
    ligand-gated ion channels
    Experimental organism
    human
    zebrafish
  32. Marc Lipsitch

    Harvard T.H. Chan School of Public Health, United States

    Expertise
    Epidemiology and Global Health
    Microbiology and Infectious Disease
    Medicine
    Research focus
    pathogen transmission modeling
    evolution of pathogens
    vaccine epidemiology
    antimicrobial resistance
    research ethics
    Experimental organism
    S. pneumoniae
  33. Ruth Loos

    The Icahn School of Medicine at Mount Sinai, United States

    Expertise
    Epidemiology and Global Health
    Medicine
    Genetics and Genomics
    Research focus
    genetic epidemiology
    obesity
    prediction
    gene discovery
    precision medicine
    Experimental organism
    human
  34. Andrew MacPherson

    University of Bern, Switzerland

    Expertise
    Immunology and Inflammation
    Medicine
    Research focus
    mucosal immunity
    function of IgA
    mechanisms of host-microbial mutualism
  35. Arduino A Mangoni

    Flinders Medical Centre, Australia

    Expertise
    Medicine
    Research focus
    clinical pharmacology
    drug safety in old age
    drug repurposing
    drug discovery
    metabolomics
    biomarkers
    cardiovascular pharmacology
    patient-centred outcomes
  36. Grant McArthur

    Peter MacCallum Cancer Centre, Australia

    Expertise
    Cancer Biology
    Medicine
    Research focus
    melanoma
  37. Jean-Pierre Michel

    University of Geneva, Switzerland

    Expertise
    Medicine
    Research focus
    aging
    geriatric medicine
    public health
    nutrition
    vaccines
  38. Subburaman Mohan

    Loma Linda University, United States

    Expertise
    Medicine
    Genetics and Genomics
    Research focus
    bone biology
    endochondral bone formation
    insulin-like growth factors
    osteoporosis
    osteoarthritis
    skeletal development
    Experimental organism
    human
  39. Zsolt Molnár

    CytoSorbents Europe GmbH, Germany
    University of Pécs, Hungary

    Expertise
    Medicine
    Research focus
    sepsis
    septic shock
    hemodynamic monitoring
    fluid therapy
    extracorporeal cytokine removal
  40. Belinda Nicolau

    McGill University, Canada

    Expertise
    Epidemiology and Global Health
    Medicine
    Research focus
    cancer epidemiology
    social determinants of health
  41. Ole Haagen Nielsen

    Herlev Hospital, University of Copenhagen, Denmark

    Expertise
    Medicine
    Research focus
    gastroenterology (especially inflammatory bowel disease)
    hepatology
    internal medicine
  42. Renata Pasqualini

    Rutgers University, United States

    Expertise
    Medicine
    Cancer Biology
    Research focus
    radiation oncology
    translational cancer research
    prostate cancer
  43. Serge Przedborski

    Columbia University Medical Center, United States

    Expertise
    Neuroscience
    Medicine
    Research focus
    Parkinson's disease
    neurodegeneration
    mitochondrial damage
    motor neuron disease
    amyotrophic lateral sclerosis
    astrocytes
    autophagy
    mitophagy
    necroptosis
    apoptosis
    Experimental organism
    human
  44. Louis Ptacek

    University of California, San Francisco, United States

    Expertise
    Neuroscience
    Medicine
    Research focus
    neurogenetics
    circadian rhythms
    sleep
    episodic disorders
    Experimental organism
    human
    mouse
  45. Peter Ratcliffe

    University of Oxford, United Kingdom

    Expertise
    Cell Biology
    Medicine
    Research focus
    hypoxia
    signaling
    hypoxia inducible factor
    prolyl hydroxylase
    oxygenase
    cysteine dioxygenase
    von Hippel-Landau
    N-degron
  46. Isabel Rodriguez-Barraquer

    University of California, San Francisco, United States

    Expertise
    Epidemiology and Global Health
    Microbiology and Infectious Disease
    Medicine
    Research focus
    dengue
    malaria
    Zika
    vector-bone diseases
    serology
    modeling
    Experimental organism
    human
  47. Antony Rosen

    Johns Hopkins University School of Medicine, United States

    Expertise
    Medicine
    Research focus
    autoimmunity
    autoimmune disease
    rheumatic
    autoantibodies
    granzyme
  48. Charles Sawyers

    Memorial Sloan-Kettering Cancer Center, United States

    Expertise
    Cancer Biology
    Medicine
    Research focus
    translational medicine
    oncology
    Experimental organism
    human
  49. Joshua T Schiffer

    Fred Hutchinson Cancer Research Center, United States

    Expertise
    Microbiology and Infectious Disease
    Epidemiology and Global Health
    Immunology and Inflammation
    Medicine
    Research focus
    HSV-2
    herpesviruses
    mucosa
    T cells
    viral shedding
    mathematical modelling
    Experimental organism
    human
    viruses
  50. Nima Sharifi

    Cleveland Clinic, United States

    Expertise
    Biochemistry and Chemical Biology
    Cancer Biology
    Medicine
    Research focus
    steroid biochemistry
    steroid metabolism
    prostate cancer
    nuclear receptors
    hormone therapy resistance
    androgens
    oncology
    Experimental organism
    mouse
  51. Dolores Shoback

    University of California, San Francisco, United States

    Expertise
    Medicine
    Research focus
    endocrinology
    metabolism
    metabolic bone disease
    calcium sensing receptor
    parathyroid hormone
    Experimental organism
    human
  52. Viviana Simon

    The Icahn School of Medicine at Mount Sinai, United States

    Expertise
    Epidemiology and Global Health
    Microbiology and Infectious Disease
    Medicine
    Research focus
    viral-host interactions
    retroviral restriction factors
    HIV drug resistance
  53. Lois Smith

    Harvard Medical School, United States

    Expertise
    Developmental Biology
    Medicine
    Neuroscience
    Research focus
    age-related macular degeneration
    diabetic eye disease
    retinopathy
    ocular disease
    Experimental organism
    mouse
  54. Margaret Stanley

    University of Cambridge, United Kingdom

    Expertise
    Cancer Biology
    Microbiology and Infectious Disease
    Medicine
    Epidemiology and Global Health
    Research focus
    vaccines
    cervix cancer
    cervix precancer
    keratinocyte biology
    human papillomavirus
    DNA viruses
    vaccine immunology
    Experimental organism
    human
  55. Kiyoshi Takeda

    Osaka University, Japan

    Expertise
    Immunology and Inflammation
    Medicine
    Research focus
    mucosal immunology
    inflammatory bowel disease
    intestinal immunity
    intestinal environmental factors
    intestinal epithelial cells
  56. Rudolph E Tanzi

    Harvard University, United States

    Expertise
    Neuroscience
    Genetics and Genomics
    Medicine
    Research focus
    Alzheimer's disease
    genetics
    neurodegenerative disease
    amyloid
    neuroinflammation
    Experimental organism
    mouse
    human
    brain organoids
  57. J Paul Taylor

    St. Jude Children's Research Hospital, United States

    Expertise
    Neuroscience
    Cell Biology
    Medicine
    Research focus
    liquid-liquid phase separation
    RNA granules
    biomolecular condensates
    neurodegeneration
    Experimental organism
    D. melanogaster
    human
  58. M Dawn Teare

    Newcastle University, United Kingdom

    Expertise
    Computational and Systems Biology
    Epidemiology and Global Health
    Medicine
    Research focus
    statistics
    population genetics
    epidemiology
  59. Peter Tontonoz

    University of California, Los Angeles, United States

    Expertise
    Cell Biology
    Medicine
    Research focus
    lipid metabolism
    cholesterol
    nuclear receptors
    adipocytes
    obesity
    atherosclerosis
    diabetes
    Experimental organism
    mouse
  60. Frank van de Veerdonk

    Radboud University Medical Center, Netherlands

    Expertise
    Immunology and Inflammation
    Microbiology and Infectious Disease
    Medicine
    Research focus
    medical mycology
    clinical immunology
  61. Jacco Wallinga

    National Institute for Public Health and the Environment, Netherlands
    Leiden University Medical Center, Netherlands

    Expertise
    Microbiology and Infectious Disease
    Epidemiology and Global Health
    Medicine
    Research focus
    modeling of infectious diseases
    vaccination
    infectious disease control
    public health
    bioinformatics
  62. Hao Zhu

    University of Texas Southwestern Medical Center, United States

    Expertise
    Cancer Biology
    Stem Cells and Regenerative Medicine
    Medicine
    Research focus
    mechanisms of tissue repair and organ regeneration
    liver cancer
    hepatocellular carcinoma
    epigenetics
    polyploidy
    Experimental organism
    human
    mouse
  63. Wilbert Zwart

    Netherlands Cancer Institute, Netherlands

    Expertise
    Cancer Biology
    Medicine
    Research focus
    breast cancer
    prostate cancer
    hormonal regulation
    epigenetics
    transcription factors
    genomic profiling
    Experimental organism
    human