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Latest articles

    1. Cell Biology
    2. Medicine

    Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo

    Sharon Elliot, Paola Catanuto ... Marilyn K Glassberg
    A systemic feature of idiopathic pulmonary fibrosis whereby urine-derived exosomes contain pro-fibrotic microRNAs and interfere with response to tissue injury.
    1. Cancer Biology
    2. Medicine

    Non-coding RNAs in drug and radiation resistance of bone and soft-tissue sarcoma: a systematic review

    Huan-Huan Chen, Tie-Ning Zhang ... Tao Zhang
    Non-coding RNAs appear to be good candidates as biomarkers for predicting treatment response and therapeutics for sarcoma, their differential expression across tissues complicates their application.
    1. Medicine

    Retinopathy of prematurity: Metabolic risk factors

    Zhongjie Fu, Anders K Nilsson ... Lois EH Smith
    An update for current knowledge gap in retinal metabolism after preterm birth and treatments for retinopathy of prematurity.
    1. Medicine

    Exploratory data on the clinical efficacy of monoclonal antibodies against SARS-CoV-2 Omicron variant of concern

    Fulvia Mazzaferri, Massimo Mirandola ... Evelina Tacconelli
    Compared with casirivimab/imdevimab and bamlanivimab/etesevimab, early treatment with sotrovimab seems to reduce the time to sustained recovery among adult outpatients with mild-to-moderate SARS-CoV-2 infection due to Omicron BA.1 and BA.1.1.
    1. Epidemiology and Global Health
    2. Medicine

    Lack of ownership of mobile phones could hinder the rollout of mHealth interventions in Africa

    Justin T Okano, Joan Ponce ... Sally Blower
    Due to current levels of mobile phone ownership in Africa, it may only be possible to scale up mHealth interventions in a few countries, but not in the vast majority of the 33 countries that encompass ~60% of Africa's population.
    1. Medicine

    Trio-based whole exome sequencing in patients with suspected sporadic inborn errors of immunity: A retrospective cohort study

    Anne Hebert, Annet Simons ... Caspar I van der Made
    Systematic assessment of de novo variants in patients with sporadic inborn errors of immunity led to the identification of promising candidate variants in known and novel immune genes, supporting its implementation in the routine diagnostic evaluation of these patients.
    1. Cell Biology
    2. Medicine

    Notch signaling functions in noncanonical juxtacrine manner in platelets to amplify thrombogenicity

    Susheel N Chaurasia, Mohammad Ekhlak ... Debabrata Dash
    Notch signaling in human platelets functions in noncanonical juxtacrine manner to amplify platelet reactivity and thrombogenicity.
    1. Medicine
    2. Microbiology and Infectious Disease

    Novel fast pathogen diagnosis method for severe pneumonia patients in the intensive care unit: randomized clinical trial

    Yan Wang, Xiaohui Liang ... Wenkui Yu
    A novel species-specific detection method could obtain pathogenic bacteria information in 4 hr with high clinical sensitivity and specificity, which guided the faster antibiotic treatment in ICU and brought some clinical benefit in a real-world scenario.

Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  3. Jonathan Roiser
    University College London, United Kingdom
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