eLife reviews translational, clinical and health policy research in all areas of medicine. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine

    Human HPSE2 gene transfer ameliorates bladder pathophysiology in a mutant mouse model of urofacial syndrome

    Filipa M. Lopes, Celine Grenier ... Neil A. Roberts
    1. Medicine

    Phosphate as an adjunct to calcium in promoting coronary vascular calcification in chronic inflammatory states

    Gordon L Klein
    Phosphate and calcium from resorbing bone can find their way to the coronary circulation and contribute to atherosclerotic calcification of the blood vessels.
    1. Computational and Systems Biology
    2. Medicine

    Single-cell transcriptome analysis of cavernous tissues reveals the key roles of pericytes in diabetic erectile dysfunction

    Seo-Gyeong Bae, Guo Nan Yin ... Jihwan Park
    Single-cell RNA sequencing analysis of diabetic mouse cavernous tissue revealed that LBH is a novel pericyte marker and may interact with Crystallin Alpha B and Vimentin to promote neurovascular regeneration.
    1. Medicine
    2. Neuroscience

    Digital wearable insole-based identification of knee arthropathies and gait signatures using machine learning

    Matthew F Wipperman, Allen Z Lin ... Olivier Harari
    Biosensor data collected by digital insoles is comparable to lab-based clinical assessments and can be used to identify subject-specific gait patterns.
    1. Medicine
    2. Microbiology and Infectious Disease

    Neuroinfectiology of an atypical anthrax-causing pathogen in wild chimpanzees

    Tobias Gräßle, Carsten Jäger ... Markus Morawski
    1. Medicine
    2. Neuroscience

    Neural mechanism of rebooting the unconsciousness caused by midazolam

    LeYuan Gu, WeiHui Shao ... HongHai Zhang
    1. Medicine

    Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam

    Nguyen Lam Vuong, Nguyen Than Ha Quyen ... Ronald B. Geskus
    1. Medicine

    Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis

    Wei Chen, Yun Lu ... Yi-Ping Li
    Low expression of Cbfb may be the cause of osteoarthritis, and local admission of Cbfb may rescue and protect against osteoarthritis through decreasing Wnt/β-catenin signaling, and increasing Hippo/Yap signaling and Tgfβ/Smad2/3 signaling in osteoarthritis articular cartilage.

Senior editors

  1. Christian Büchel
    University Medical Center Hamburg-Eppendorf, Germany
  2. Diane M Harper
    University of Michigan, United States
  3. Wei Yan
    University of California, Los Angeles, United States
  4. See more editors