Medicine

Latest articles

1. 1. Medicine

   Noninvasive ultrasound targeted modulation of calcium influx in splenic immunocytes potentiates antineoplastic immunity attenuating hepatocellular carcinoma proliferation

   Wei Dong, Guihu Wang ... Zongfang Li
2. 1. Medicine
   2. Stem Cells and Regenerative Medicine

   Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

   M Reza Bahranifard, Jessica Chan ... C Ross Ethier

   Magnetically steered mesenchymal stem cells significantly lowered intraocular pressure for 9 months in mice, motivating the translation of this technology for the treatment of glaucoma.
3. 1. Cell Biology
   2. Medicine

   The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

   Fan Zhang, Yuan Wang ... Xianpeng Ge

   CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.
4. 1. Immunology and Inflammation
   2. Medicine

   C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

   Toru Tanaka, Naoto Sasaki ... Yoshiyuki Rikitake

   CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
5. 1. Medicine

   Serum, Cell-Free, HPV-Human DNA Junction Detection and HPV Typing for Predicting and Monitoring Cervical Cancer Recurrence

   Anne Van Arsdale, Olga Mescheryakova ... Jack Lenz
6. 1. Cancer Biology
   2. Medicine

   Gamma Knife stereotactic radiotherapy combined with tislelizumab as later-line therapy in pMMR/MSS/MSI-L metastatic colorectal cancer: a phase II trial analysis

   Yiran Zhang, Hanyang Guan ... Jinghua Pan

   Patients with microsatellite stable/low microsatellite instability mismatch repair-proficient metastatic colorectal cancer may be sensitive to tislelizumab treatment after receiving Gamma Knife stereotactic radiotherapy.
7. 1. Medicine

   Addressing cultural and knowledge barriers to enable preclinical sex inclusive research

   Brianna N Gaskill, Benjamin Phillips ... Natasha A Karp
8. 1. Medicine

   Cell-autonomous and non-cell-autonomous effects of arginase-II on cardiac aging

   Duilio M Potenza, Xin Cheng ... Xiu-Fen Ming
9. 1. Medicine

   Aging: Multiple roles for a mitochondrial enzyme

   Xicong Tang, Hongyu Qiu

   The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.
10. 1. Medicine

    Early menarche and childbirth accelerate aging-related outcomes and age-related diseases: Evidence for antagonistic pleiotropy in humans

    Yifan Xiang, Vineeta Tanwar ... Pankaj Kapahi