Medicine

Latest articles

1. 1. Medicine

   The MODY-associated TALK-1 L114P mutation causes islet α-cell overactivity and β-cell inactivity resulting in transient neonatal diabetes and glucose dyshomeostasis in adults

   Arya Y. Nakhe, Prasanna K. Dadi ... David A. Jacobson
2. 1. Medicine

   SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury

   Xiaoyan Yang, Hsiang-Chun Chang ... Hossein Ardehali
3. 1. Medicine

   An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo

   Luyang Cao, Lixiang Ma ... Jingsong Xu

   Neutrophils are the predominant phagocytes that clear dead liver cells under normal physiological conditions.
4. 1. Medicine
   2. Neuroscience

   Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

   Yunlu Xue, Constance L. Cepko
5. 1. Genetics and Genomics
   2. Medicine

   Association between APOL1 risk variants and the occurrence of sepsis in patients hospitalized with infections

   Lan Jiang, Ge Liu ... QiPing Feng
6. 1. Medicine

   Identification of Novel Syncytiotrophoblast Membrane Extracellular Vesicles Derived Protein Biomarkers in Preeclampsia: A Cross-Sectional Study

   Toluwalase Awoyemi, Shuhan Jiang ... Manu Vatish
7. 1. Computational and Systems Biology
   2. Medicine

   A computational model predicts sex-specific responses to calcium channel blockers in mesenteric vascular smooth muscle

   Gonzalo Hernandez-Hernandez, Samantha C. O’Dwyer ... Colleen E. Clancy
8. 1. Epidemiology and Global Health
   2. Medicine
   3. Cancer Biology

   

   Special Issue: The impact of the COVID-19 pandemic on cancer prevention, control, care and survivorship

   Edited by Eduardo Franco et al.

   Our latest Special Issue brings together research covering many different aspects of the impact of the COVID-19 pandemic on cancer outcomes across the globe.
9. 1. Medicine

   Loss of Ptpmt1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice

   Hong Zheng, Qianjin Li ... Cheng-Kui Qu

   The balanced utilization of energy sources, namely carbohydrates and fats, by mitochondria, is critically important for the long-term maintenance of both skeletal muscle and heart health.
10. 1. Epidemiology and Global Health
    2. Medicine

    Development and validation of COEWS (COVID-19 Early Warning Score) for hospitalized COVID-19 with laboratory features: A multicontinental retrospective study

    Riku Klén, Ivan A Huespe ... David Gómez-Varela

    The new early warning system, COEWS, will improve the early identification and management of high-risk COVID-19 patients compared to the widely used NEWS2 by using easy-to-obtain clinical parameters that have been externally validated in a diverse multicontinental cohort of patients.