Medicine

Latest articles

1. 1. Cell Biology
   2. Medicine

   Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo

   Sharon Elliot, Paola Catanuto ... Marilyn K Glassberg

   A systemic feature of idiopathic pulmonary fibrosis whereby urine-derived exosomes contain pro-fibrotic microRNAs and interfere with response to tissue injury.
2. 1. Medicine
   2. Physics of Living Systems

   High spatial resolution analysis using automated indentation mapping differentiates biomechanical properties of normal vs. degenerated articular cartilage in mice

   Anand O Masson, Bryce Besler ... Roman J Krawetz
3. 1. Cancer Biology
   2. Medicine

   Non-coding RNAs in drug and radiation resistance of bone and soft-tissue sarcoma: a systematic review

   Huan-Huan Chen, Tie-Ning Zhang ... Tao Zhang

   Non-coding RNAs appear to be good candidates as biomarkers for predicting treatment response and therapeutics for sarcoma, their differential expression across tissues complicates their application.
4. 1. Medicine

   Retinopathy of prematurity: Metabolic risk factors

   Zhongjie Fu, Anders K Nilsson ... Lois EH Smith

   An update for current knowledge gap in retinal metabolism after preterm birth and treatments for retinopathy of prematurity.
5. 1. Medicine

   Exploratory data on the clinical efficacy of monoclonal antibodies against SARS-CoV-2 Omicron variant of concern

   Fulvia Mazzaferri, Massimo Mirandola ... Evelina Tacconelli

   Compared with casirivimab/imdevimab and bamlanivimab/etesevimab, early treatment with sotrovimab seems to reduce the time to sustained recovery among adult outpatients with mild-to-moderate SARS-CoV-2 infection due to Omicron BA.1 and BA.1.1.
6. 1. Epidemiology and Global Health
   2. Medicine

   Lack of ownership of mobile phones could hinder the rollout of mHealth interventions in Africa

   Justin T Okano, Joan Ponce ... Sally Blower

   Due to current levels of mobile phone ownership in Africa, it may only be possible to scale up mHealth interventions in a few countries, but not in the vast majority of the 33 countries that encompass ~60% of Africa's population.
7. 1. Medicine

   Trio-based whole exome sequencing in patients with suspected sporadic inborn errors of immunity: A retrospective cohort study

   Anne Hebert, Annet Simons ... Caspar I van der Made

   Systematic assessment of de novo variants in patients with sporadic inborn errors of immunity led to the identification of promising candidate variants in known and novel immune genes, supporting its implementation in the routine diagnostic evaluation of these patients.
8. 1. Cell Biology
   2. Medicine

   Notch signaling functions in noncanonical juxtacrine manner in platelets to amplify thrombogenicity

   Susheel N Chaurasia, Mohammad Ekhlak ... Debabrata Dash

   Notch signaling in human platelets functions in noncanonical juxtacrine manner to amplify platelet reactivity and thrombogenicity.
9. 1. Medicine
   2. Neuroscience

   Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice

   Eva M Szego, Laura Malz ... Hella Luksch
10. 1. Medicine
    2. Microbiology and Infectious Disease

    Novel fast pathogen diagnosis method for severe pneumonia patients in the intensive care unit: randomized clinical trial

    Yan Wang, Xiaohui Liang ... Wenkui Yu

    A novel species-specific detection method could obtain pathogenic bacteria information in 4 hr with high clinical sensitivity and specificity, which guided the faster antibiotic treatment in ICU and brought some clinical benefit in a real-world scenario.