Medicine

Medicine

eLife reviews translational, clinical and health policy research in all areas of medicine. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine

    Therapeutic effects of PDGF-AB/BB against cellular senescence in human intervertebral disc

    Changli Zhang, Martha Elena Diaz-Hernandez ... Hicham Drissi
    PDGF mitigated cellular senescence in human intervertebral disc by modulating cell cycle, inflammation, and mitochondria function, offering a potential strategy for combating age-induced disc degeneration.
    1. Genetics and Genomics
    2. Medicine

    EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis

    Lianlei Wang, Xinyu Yang ... Nan Wu
    EPHA4 pathway dysfunction causes axon pathfinding defects, resulting in impaired coordinated left-right locomotion by disrupting neural patterning and the function of central pattern generators, thereby potentially leading to idiopathic scoliosis.
    1. Medicine
    2. Immunology and Inflammation

    A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies

    Thomas Balligand, Claire Carpenet ... Maarten Dewilde
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Medicine

    Gender differences in submission behavior exacerbate publication disparities in elite journals

    Chaoqun Ni, Isabel Basson ... Vincent Larivière
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

    M Reza Bahranifard, Jessica Chan ... C Ross Ethier
    Magnetically steered mesenchymal stem cells significantly lowered intraocular pressure for 9 months in mice, motivating the translation of this technology for the treatment of glaucoma.
    1. Cell Biology
    2. Medicine

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge
    CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.
    1. Immunology and Inflammation
    2. Medicine

    C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

    Toru Tanaka, Naoto Sasaki ... Yoshiyuki Rikitake
    CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
    1. Medicine

    Serum, Cell-Free, HPV-Human DNA Junction Detection and HPV Typing for Predicting and Monitoring Cervical Cancer Recurrence

    Anne Van Arsdale, Olga Mescheryakova ... Jack Lenz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete

Senior editors

  1. Balram Bhargava
    Indian Council of Medical Research, India
  2. Christopher L-H Huang
    University of Cambridge, United Kingdom
  3. Caigang Liu
    Shengjing Hospital of China Medical University, China
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