Medicine

Latest articles

1. 1. Medicine

   Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment

   Zhao Shan et al.
2. 1. Genetics and Genomics
   2. Medicine

   Tendon and motor phenotypes in the Crtap^-/- mouse model of recessive osteogenesis imperfecta

   Matthew William Grol et al.

   Ultrastructural, biochemical, and behavioral assessments reveal that the Crtap^-/- mouse model of severe, recessive Osteogenesis Imperfecta presents with defects in tendon structure and strength that correlate with severe motor deficits.
3. 1. Computational and Systems Biology
   2. Medicine

   Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction

   Muhammad Arif et al.

   Elucidating widespread and tissue-specific biological process alterations after myocardial infaction in metabolically active tissues using systems biology approaches.
4. 1. Medicine
   2. Neuroscience

   Stimulus-induced gamma rhythms are weaker in human elderly with Mild Cognitive Impairment and Alzheimer's Disease

   Dinavahi VPS Murty et al.
5. 1. Computational and Systems Biology
   2. Medicine

   Heart Attack: Working together

   Regan Odongo, Tunahan Çakır

   Heart attacks have a ripple effect on how other organs exchange biomolecules that help the heart respond to injury.
6. 1. Epidemiology and Global Health
   2. Medicine

   Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population

   Heli Julkunen et al.

   Metabolic biomarkers measured from single blood test can identify apparently healthy people at high susceptibility for developing severe pneumonia, and may also be useful for preventive COVID-19 screening.
7. 1. Epidemiology and Global Health
   2. Medicine

   An agnostic study of associations between ABO and RhD blood group and phenome-wide disease risk

   Torsten Dahlén et al.

   The relationship between blood groups and disease is detangled, without preconceived ideas, using population-wide data, with millions of participants and lifetime follow-up, identifying not only previously known relationships but also new insights.
8. 1. Medicine

   Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer

   Fernanda I Staquicini et al.

   A peptide motif targeting tumor-infiltrating macrophage in triple-negative breast cancer delays tumor growth and favors an antitumor immune response.
9. 1. Epidemiology and Global Health
   2. Medicine

   Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data

   Ewan Cameron et al.

   A demonstration of the power of routine case data and statistical modelling to guide the allocation of anti-malarial interventions in a resource-constrained setting.
10. 1. Medicine

    Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients

    Christian A Di Buduo et al.

    A 3D bone marrow niche that reproduces megakaryocyte differentiation and ex vivo platelet production from hematopoietic progenitors and iPSCs of thrombocytopenic patients predicts individual response to Eltrombopag accurately.