Medicine

Latest articles

1. 1. Computational and Systems Biology
   2. Medicine

   Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction

   Muhammad Arif et al.
2. 1. Medicine

   Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

   Andrea Milzi et al.

   Assessing plaque biomechanics by optical coherence tomography highlights the importance of the disrupting effects of plaque stress, bringing stress concentrations as the prime movers of plaque rupture back into clinical practice.
3. 1. Medicine
   2. Neuroscience

   Recovery of consciousness and cognition after general anesthesia in humans

   George A Mashour et al.
4. 1. Medicine

   Asprosin-neutralizing antibodies as a treatment for metabolic syndrome

   Ila Mishra et al.

   Anti-asprosin monoclonal antibodies, a promising pharmacotherapy for the treatment of metabolic syndrome-associated hyperglycemia, obesity, and dyslipidemia.
5. 1. Computational and Systems Biology
   2. Medicine

   Computational modeling identifies embolic stroke of undetermined source patients with potential arrhythmic substrate

   Savannah F Bifulco et al.
6. 1. Cell Biology
   2. Medicine

   eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

   Takeshi Ninchoji et al.

   Vascular leakage from pathological vessels in retinopathy aggravates the disease, but endothelial junction stability and barrier integrity can be restored by blocking formation of nitric oxide.
7. 1. Medicine
   2. Neuroscience

   Quantifying noxious-evoked baseline sensitivity in neonates to optimise analgesic trials

   Maria M Cobo et al.

   Measuring individual differences in noxious-evoked baseline sensitivity in neonates can substantially reduce sample sizes required in neonatal analgesic trials.
8. 1. Medicine

   Sensitivity of ID NOW and RT–PCR for detection of SARS-CoV-2 in an ambulatory population

   Yuan-Po Tu et al.

   Although the ID NOW platform is less sensitive than RT–PCR for identification of SARS-CoV-2 infection, it provides high positive and negative predictive values in low-prevalence populations.
9. 1. Medicine
   2. Neuroscience

   AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

   Yunlu Xue et al.

   AAV-Txnip prolongs vision in mouse models of blindness, enhancing lactate catabolism, mitochondrial health, and ATP production in a condition that likely has a limited glucose supply.
10. 1. Medicine
    2. Neuroscience

    The mechanism underlying transient weakness in myotonia congenita

    Jessica H Myers et al.

    Transient weakness in myotonia congenita is caused by depolarization secondary to activation of persistent Na⁺ current in skeletal muscle.