Medicine

Medicine

eLife reviews translational, clinical and health policy research in all areas of medicine. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Chromosomes and Gene Expression
    2. Medicine

    Gene dosage imbalance disrupts systemic metabolism in the Dp16 Down syndrome mouse model

    Fangluo Chen, Muzna Saqib ... G William Wong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Medicine

    Large-scale synthetic data enable digital twins of human excitable cells

    Pei-Chi Yang, Mao-Tsuen Jeng ... Colleen E Clancy
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Medicine

    Single transcript level atlas of oxytocin and the oxytocin receptor in the mouse brain

    Vitaly Ryu, Anisa Azatovna Gumerova ... Mone Zaidi
    The compendium of oxytocin and its receptor in the brain could provide further insights into the peripheral and central effects of oxytocin in health and disease.
    1. Computational and Systems Biology
    2. Medicine

    Global molecular landscape of early MASLD progression in human obesity

    Qing Zhao, William De Nardo ... Philipp Kaldis
    GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.
    1. Cell Biology
    2. Medicine

    Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Medicine

    Sperm motility in mice with oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA

    Charline Vilpreux, Paul Fourquin ... Jessica Escoffier
    Naked mRNA administration in the testes rescues sperm function, demonstrating a potential therapeutic approach for genetic male infertility.
    1. Medicine

    Gender differences in submission behavior exacerbate publication disparities in elite journals

    Chaoqun Ni, Isabel Basson ... Vincent Larivière
    Gender differences in submission behavior, driven by self-perceptions of novelty and peer discouragement, limit women’s representation in high-impact journals and, in turn, their scientific visibility and career advancement.
    1. Medicine
    2. Immunology and Inflammation

    A translational transcriptomic signature of vaccine reactogenicity for the evaluation of novel formulations

    Jérémie Becker, Maroussia Roelens ... Laurent Beloeil
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Medicine
    2. Neuroscience

    Juvenile reinstatement of TCF4 in Pitt-Hopkins syndrome model mice reveals a critical window for genetic intervention

    Lucas M James, Carlee A Friar ... Benjamin D Philpot
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling

Senior editors

  1. Olujimi A Ajijola
    University of California, Los Angeles, United States
  2. Tony Ng
    King's College London, United Kingdom
  3. Ma-Li Wong
    State University of New York Upstate Medical University, United States
  4. See more editors