Medicine

Latest articles

1. 1. Medicine
   2. Cancer Biology

   Monitoring Circulating Cell-free HPV DNA in Metastatic and Recurrent Cervical Cancer: Clinical Importance and Implications for Treatment - A Pilot Study

   Zhuomin Yin, Tao Feng ... Hanmei Lou
2. 1. Medicine

   Therapeutic effects of PDGF-AB/BB against cellular senescence in human intervertebral disc

   Changli Zhang, Martha Elena Diaz-Hernandez ... Hicham Drissi

   PDGF mitigated cellular senescence in human intervertebral disc by modulating cell cycle, inflammation, and mitochondria function, offering a potential strategy for combating age-induced disc degeneration.
3. 1. Genetics and Genomics
   2. Medicine

   EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis

   Lianlei Wang, Xinyu Yang ... Nan Wu

   EPHA4 pathway dysfunction causes axon pathfinding defects, resulting in impaired coordinated left-right locomotion by disrupting neural patterning and the function of central pattern generators, thereby potentially leading to idiopathic scoliosis.
4. 1. Medicine
   2. Immunology and Inflammation

   A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies

   Thomas Balligand, Claire Carpenet ... Maarten Dewilde
5. 1. Medicine

   Gender differences in submission behavior exacerbate publication disparities in elite journals

   Chaoqun Ni, Isabel Basson ... Vincent Larivière
6. 1. Medicine

   Noninvasive ultrasound targeted modulation of calcium influx in splenic immunocytes potentiates antineoplastic immunity attenuating hepatocellular carcinoma proliferation

   Wei Dong, Guihu Wang ... Zongfang Li
7. 1. Medicine
   2. Stem Cells and Regenerative Medicine

   Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

   M Reza Bahranifard, Jessica Chan ... C Ross Ethier

   Magnetically steered mesenchymal stem cells significantly lowered intraocular pressure for 9 months in mice, motivating the translation of this technology for the treatment of glaucoma.
8. 1. Cell Biology
   2. Medicine

   The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

   Fan Zhang, Yuan Wang ... Xianpeng Ge

   CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.
9. 1. Immunology and Inflammation
   2. Medicine

   C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

   Toru Tanaka, Naoto Sasaki ... Yoshiyuki Rikitake

   CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.
10. 1. Medicine

    Serum, Cell-Free, HPV-Human DNA Junction Detection and HPV Typing for Predicting and Monitoring Cervical Cancer Recurrence

    Anne Van Arsdale, Olga Mescheryakova ... Jack Lenz