Medicine

Medicine

eLife publishes translational, clinical and health policy research in all areas of medicine. Learn more about what we publish and sign up for the latest research.
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Latest articles

    1. Medicine
    2. Structural Biology and Molecular Biophysics

    Allosteric communication in class A β-lactamases occurs via cooperative coupling of loop dynamics

    Ioannis Galdadas et al.
    A combination of equilibrium and nonequilibrium molecular dynamics simulations is an effective tool to study allosteric communications in ultrafast enzymes that show little or no conformational changes.
    1. Medicine
    2. Neuroscience

    Respiratory depression and analgesia by opioid drugs in freely behaving larval zebrafish

    Shenhab Zaig et al.
    Emerging approaches in larval zebrafish to identify safe opioid therapies without the side-effect of respiratory depression.
    1. Cell Biology
    2. Medicine

    Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8

    Hsiang-Chun Chang et al.
    Mammalian cellular iron homeostasis and the maturation of the cytosolic iron sulfur cluster proteins are dependent on the mitochondrial protein import machinery.
    1. Epidemiology and Global Health
    2. Medicine

    SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung

    Alan E Mast et al.
    Transcription changes in cells taken from bronchoalveolar fluid of COVID-19 patients indicate severe disruption of coagulation and fibrinolytic pathways in the lung and suggest similar processes in other organs.
    1. Chromosomes and Gene Expression
    2. Medicine

    Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells

    Karthik Amudhala Hemanthakumar et al.
    Endothelial dysfunction due to cardiovascular disease risk factors explained by cardiac endothelial cell transcriptome remodelling.

Senior editors

  1. Christian Büchel
    University Medical Center Hamburg-Eppendorf, Germany
  2. Y M Dennis Lo
    The Chinese University of Hong Kong, Hong Kong SAR China
  3. Huda Zoghbi
    Huda Zoghbi
    Baylor College of Medicine and Texas Children's Hospital, United States, United States
  4. See more editors