Medicine

Latest articles

1. 1. Medicine
   2. Microbiology and Infectious Disease

   An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis

   Nguyen Thi Thuy Ngan et al.

   Despite evidence of significant anti-cryptococcal activity in vitro and animal models, including synergy with other antifungal agents, high-dose tamoxifen has no impact on cerebrospinal fluid sterilization in cryptococcal meningitis.
2. 1. Medicine

   Infrared molecular fingerprinting of blood-based liquid biopsies for the detection of cancer

   Marinus Huber et al.

   The combination of molecular infrared fingerprinting and machine learning enables the detection of breast, bladder, prostate, and lung cancer based on liquid blood serum and plasma, providing a general framework for the minimally invasive investigation of oncological conditions.
3. 1. Medicine

   Modulation of fracture healing by the transient accumulation of senescent cells

   Dominik Saul et al.

   Senescent cells accumulate in the fracture callus and a reduction in the number of these cells accelerates fracture healing in mice.
4. 1. Medicine
   2. Neuroscience

   scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution

   Bilge E Öztürk et al.
5. 1. Cell Biology
   2. Medicine

   An experimental test of the effects of redacting grant applicant identifiers on peer review outcomes

   Richard Nakamura et al.
6. 1. Medicine
   2. Microbiology and Infectious Disease

   Combination of inflammatory and vascular markers in the febrile phase of dengue is associated with more severe outcomes

   Nguyen Lam Vuong et al.

   Relationships of biomarkers with clinical outcome differed between children and adults and the best combinations associated with moderate/severe dengue comprised of six/seven vascular and immune biomarkers.
7. 1. Biochemistry and Chemical Biology
   2. Medicine

   Early prediction of in-hospital death of COVID-19 patients: a machine-learning model based on age, blood analyses, and chest x-ray score

   Emirena Garrafa et al.
8. 1. Developmental Biology
   2. Medicine

   β-Catenin-NFkB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

   Shikai Hu et al.
9. 1. Genetics and Genomics
   2. Medicine

   SMA-miRs (miR-181a-5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples

   Emanuela Abiusi et al.

   The identification of SMA-miR supports the pathogenic role of skeletal muscle in spinal muscular atrophy and, integrated in the SMA-score, may help to improve the phenotypic prediction for patients.
10. 1. Cancer Biology
    2. Medicine

    Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking

    Shuhua Cheng et al.

    Comparative analysis establishes genetic links among angioimmunoblastic T-cell lymphoma (AITL), clonal hematopoiesis, and concomitant hematologic malignancies, and provides insights into the cell of origin, etiology, and biomarker discovery for AITL.