eLife reviews translational, clinical and health policy research in all areas of medicine. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine

    Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis

    Kentaro Homan, Tomohiro Onodera ... Norimasa Iwasaki
    1. Medicine
    2. Neuroscience

    Acute ampakines increase voiding function and coordination in a rat model of SCI

    Sabhya Rana, Firoj Alom ... Aaron D Mickle
    1. Medicine

    Autonomous metabolic reprogramming and oxidative stress characterize endothelial dysfunction in acute myocardial infarction

    Erika Zodda, Olga Tura-Ceide ... Marta Cascante
    Acute myocardial infarction patient-derived endothelial cells display a strong mitochondrial proton coupling with excess ROS production, enhanced glutamine metabolism and a carbon source switch from glucose to glutamine.
    1. Medicine

    Metabolomics identifies and validates serum androstenedione as novel biomarker for diagnosing primary angle closure glaucoma and predicting the visual field progression

    Shengjie Li, Jun Ren ... Wenjun Cao
    Metabolomic analyses have developed and validated serum androstenedione as a reliable and effective diagnostic and predictive biomarker for primary angle closure glaucoma in clinical routines.
    1. Medicine

    Viral Infections: Race against dengue

    Swee Sen Kwek, Eng Eong Ooi
    Understanding the kinetics of dengue viruses in the bloodstream can provide insights into the clinical outcomes of the disease.
    Formats available:
    • HTML
    • PDF
    1. Medicine

    Correlated signatures of social behavior in cerebellum and anterior cingulate cortex

    Sung Won Hur, Karen Safaryan ... Peyman Golshani
    Development of a novel open-source device, 'E-Scope,' to simultaneously record electrophysiology and calcium imaging in freely behaving animals, discovering co-modulation of the cerebellum, and anterior cingulate cortex during social interaction.
    1. Computational and Systems Biology
    2. Medicine

    A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle

    Gonzalo Hernandez-Hernandez, Samantha C O'Dwyer ... Colleen E Clancy
    A computer model predicts different mechanisms of blood pressure regulation and effective hypertensive therapy for males and females, thereby serving as a foundational tool for improved treatment precision.

Senior editors

  1. Wafik S El-Deiry
    Brown University, United States
  2. Caigang Liu
    Shengjing Hospital of China Medical University, China
  3. Ma-Li Wong
    State University of New York Upstate Medical University, United States
  4. See more editors