Medicine

Medicine

eLife publishes translational, clinical and health policy research in all areas of medicine. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine

    Science Forum: Improving preclinical studies through replications

    Natascha Ingrid Drude et al.
    Increasing validity should be a priority when deciding which preclinical experiments to replicate and when performing replications.
    1. Immunology and Inflammation
    2. Medicine

    The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline

    Danielle Janosevic et al.
    Single-cell RNA-sequencing identifies the precise cellular and molecular events that occur along the sepsis timeline in the kidney, pointing to potential biomarkers and therapeutic targets.
    1. Medicine

    The gut microbiota is a transmissible determinant of skeletal maturation

    Abdul Malik Tyagi et al.
    The gut microbiota is a non-genomic, transmissible regulator of bone volume, structure, and turnover.
    1. Evolutionary Biology
    2. Medicine

    Developing a theoretical evolutionary framework to solve the mystery of parturition initiation

    Antonis Rokas et al.
    This review considers the evolutionary processes and physiological mechanisms that maintain or end pregnancy in mammals to formulate general, testable theoretical models that provide insights into the biology of parturition.
    1. Cell Biology
    2. Medicine

    Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

    Jin Rong Ow et al.
    Loss of hepatic Cdk1 leads to oxidative stress, increased fatty acids in blood, and hyperinsulinemia, which resulted in insulin resistance and hepatic steatosis, similar as in diabetes.
    1. Cell Biology
    2. Medicine

    Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis

    Zhonghao Deng et al.
    Def6 functions as a novel immunoregulator in bone cells via endogenous type-I interferon response to regulate bone remodeling.
    1. Cell Biology
    2. Medicine

    An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

    Hong Wang et al.
    A non-canonical p53 function in adipocyte plays a critical role in energy homeostasis and is involved in obesity-associated metabolic dysfunctions.

Highlights

    1. Medicine
    2. Neuroscience

    Excitation, inhibition and autism

    Charlotte M Pretzsch, Dorothea L Floris
    1. Medicine

    COVID-19 papers have fewer women first authors

    Jens Peter Andersen et al.
    1. Medicine

    Drug Discovery: From worms to fish to mice

    Guy M Benian, Hyojung J Choo

Senior editors

  1. Matthias Barton
    University of Zurich, Switzerland
  2. Wafik S El-Deiry
    Brown University, United States
  3. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  4. See more editors