Medicine

Latest articles

1. 1. Genetics and Genomics
   2. Medicine

   PTPRG is an ischemia risk locus essential for HCO₃^--dependent regulation of endothelial function and tissue perfusion

   Kristoffer B Hansen et al.
2. 1. Medicine

   Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral–bacterial interactions

   Ilja L Kruglikov et al.

   Dysfunctionaladipose tissue puts obese and type 2 diabetic patients at higher risk.
3. 1. Medicine

   Performance of a deep learning based neural network in the selection of human blastocysts for implantation

   Charles L Bormann et al.
4. 1. Medicine
   2. Epidemiology and Global Health

   Reducing respiratory syncytial virus (RSV) hospitalization in a lower-income country by vaccinating mothers-to-be and their households

   Samuel PC Brand et al.

   Targeting the mothers, and other household members, of newborns with a mixture of respiratory syncytial virus (RSV) vaccines is both efficient and effective at reducing RSV hospitalizations.
5. 1. Medicine

   Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome

   Simone Bersini et al.

   Direct reprogramming of smooth muscle cells from HGPS patients revealed that BMP4 is a key contributor of vascular degeneration and might represent a new therapeutic target.
6. 1. Medicine

   Metabolic response of blood vessels to TNFα

   Abidemi Junaid et al.

   The metabolic readout of endothelial function in the microvessels-on-a-chip facilitates mechanistic studies and detection of biomarkers for microvascular diseases in a physiological relevant environment.
7. 1. Immunology and Inflammation
   2. Medicine

   3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography

   Marina Eckermann et al.

   Phase contrast X-ray tomography based on a combination of parallel and cone beam geometry extends conventional histology by a third dimension and enables full quantication of tissue remodeling in COVID-19.
8. 1. Medicine

   Inference from longitudinal laboratory tests characterizes temporal evolution of COVID-19-associated coagulopathy (CAC)

   Colin Pawlowski et al.

   Longitudinal laboratory testing results tied to SARS-CoV-2 diagnostic PCR results of more than 2500 patients reveal the temporal evolution of COVID-associated coagulopathy.
9. 1. Medicine
   2. Neuroscience

   What is the true discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia?

   Dan Valsky et al.

   Aberrant striatal signaling does not induce drastic changes in the spontaneous discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia.
10. 1. Medicine
    2. Neuroscience

    Neural signatures of α2-Adrenergic agonist-induced unconsciousness and awakening by antagonist

    Jesus Javier Ballesteros et al.

    Instant performance recovery is possible following general anesthesia-induced unconsciousness using antagonist, and the brain dynamics return abruptly to the awake state without intermediate recovery states.