Medicine

Latest articles

1. 1. Medicine
   2. Neuroscience

   NE contribution to rebooting unconsciousness caused by midazolam

   LeYuan Gu, WeiHui Shao ... HongHai Zhang
2. 1. Medicine

   Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis

   Paul Horn, Jenny Norlin ... Philip N Newsome

   Antibody-mediated neutralisation of Gremlin-1 was ineffective in treating fibrosis in metabolic dysfunction-associated steatohepatitits, likely due to low hepatic expression in a subset of myofibroblasts and redundant Gremlin-1 signalling.
3. 1. Medicine

   Enhancing Bone Regeneration and Osseointegration using rhPTH(1-34) and Dimeric ^R25CPTH(1-34) in an Osteoporotic Beagle Model

   Jeong-Oh Shin, Jong-Bin Lee ... Jin-Woo Kim
4. 1. Medicine
   2. Neuroscience

   Pain Management: A promising alternative to opioids

   Jie Zhang, Jianguo Cheng

   A complex extracted from the amniotic membrane in humans reduces post-surgical pain in mice by directly inhibiting pain-sensing neurons.
5. 1. Medicine
   2. Neuroscience

   Machine learning and biological validation identify sphingolipids as potential mediators of paclitaxel-induced neuropathy in cancer patients

   Jörn Lötsch, Khayal Gasimli ... Marco Sisignano

   Sphinganine-1-phosphate (SA1P) is linked to paclitaxel-induced peripheral neuropathy, offering a potential target for reducing this severe side effect of paclitaxel treatment.
6. 1. Medicine

   Evaluation of Clonal Hematopoiesis and Mosaic Loss of Y Chromosome in Cardiovascular Risk: an analysis in prospective studies

   Sami Fawaz, Severine Marti ... Thierry Couffinhal
7. 1. Medicine
   2. Neuroscience

   Lost in translation: Inconvenient truths on the utility of mouse models in Alzheimer’s disease research

   Alberto Granzotto, Bryce Vissel, Stefano L Sensi

   A critical review of the limitations posed by current preclinical animal models of Alzheimer's disease and of the oversimplistic assumptions proposed by the amyloid cascade hypothesis (ACH).
8. 1. Medicine

   A new preprocedural predictive risk model for post-endoscopic retrograde cholangiopancreatography pancreatitis: The SuPER model

   Mitsuru Sugimoto, Tadayuki Takagi ... Hiromasa Ohira
9. 1. Medicine
   2. Immunology and Inflammation

   Complement 3a Receptor 1 on Macrophages and Kupffer cells is not required for the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease

   Edwin A Homan, Ankit Gilani ... James C Lo
10. 1. Medicine
    2. Neuroscience

    Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia

    Naidi Sun, Yu-Yo Sun ... Song Hu