Medicine

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Medicine

   Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells

   Karthik Amudhala Hemanthakumar et al.

   Endothelial dysfunction due to cardiovascular disease risk factors explained by cardiac endothelial cell transcriptome remodelling.
2. 1. Medicine
   2. Neuroscience

   AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

   Yunlu Xue et al.
3. 1. Chromosomes and Gene Expression
   2. Medicine

   Cardiovascular Disease: Exploring risk factors at the molecular level

   Martina Rudnicki, Tara L Haas

   Risk factors for cardiovascular diseases trigger molecular changes that harm the endothelial cells in the heart, but exercise can suppress these effects.
4. 1. Medicine
   2. Neuroscience

   Quantifying individual noxious-evoked baseline sensitivity to optimise analgesic trials in neonates

   Maria M Cobo et al.
5. 1. Immunology and Inflammation
   2. Medicine

   An open label trial of anakinra to prevent respiratory failure in COVID-19

   Evdoxia Kyriazopoulou et al.

   Early suPAR-guided anakinra decreases the risk for severe respiratory failure in SARS-CoV-2 pneumonia and restores the pro-/anti-inflammatory balance.
6. 1. Epidemiology and Global Health
   2. Medicine

   Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: a controlled before-and-after trial

   Jackie Knee et al.
7. 1. Cell Biology
   2. Medicine

   Augmenter of Liver Regeneration regulates cellular iron homeostatis by modulating mitochondrial transport of ATP-binding cassette B8

   Hsiang-Chun Chang et al.
8. 1. Immunology and Inflammation
   2. Medicine

   Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

   Juana Serrano-Lopez et al.
9. 1. Medicine
   2. Neuroscience

   tTARGIT AAVs mediate the sensitive and flexible manipulation of intersectional neuronal populations in mice

   Paul V Sabatini et al.

   tTARGIT AAVs offer a new approach to manipulate intersectional populations that produce selective and robust transgene expression and are easily modified.
10. 1. Computational and Systems Biology
    2. Medicine

    Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial

    Dimitrios Chantzichristos et al.

    A human experimental model for physiological glucocorticoid exposure and glucocorticoid withdrawal identifies a multi-omic cluster, including microRNA miR-122-5p and metabolites, associated with glucocorticoid-responsive genes.