Medicine

Latest articles

1. 1. Medicine
   2. Neuroscience

   The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial

   Gansheng Tan, Anna L Huguenard ... Eric C Leuthardt

   Transcutaneous auricular vagus nerve stimulation is a safe neuromodulatory treatment for subarachnoid hemorrhage patients, with potential benefits for restoring autonomic balance.
2. 1. Immunology and Inflammation
   2. Medicine

   Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease

   Edwin A Homan, Ankit Gilani ... James C Lo

   Ablation of the G-protein-coupled receptor C3aR1 specifically on macrophages or Kupffer cells does not alter the course of metabolic dysfunction-associated steatotic liver disease in a dietary mouse model.
3. 1. Medicine
   2. Neuroscience

   CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis

   Ayni Sharif, Matthew S Jeffers ... Manoj M Lalu
4. 1. Medicine
   2. Immunology and Inflammation

   A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies

   Thomas Balligand, Claire Carpenet ... Maarten Dewilde
5. 1. Medicine

   Ocular biomarker profiling after complement factor I gene therapy in geographic atrophy secondary to age-related macular degeneration

   Thomas M Hallam, Emanuela Gardenal ... Amy V Jones
6. 1. Immunology and Inflammation
   2. Medicine

   JAK inhibition decreases the autoimmune burden in Down syndrome

   Angela L Rachubinski, Elizabeth Wallace ... Joaquín M Espinosa

   Treatment with a JAK inhibitor normalizes multiple biomarkers of autoinflammation and provides therapeutic benefit for diverse immune skin conditions in individuals with Down syndrome.
7. 1. Immunology and Inflammation
   2. Medicine

   NK cell exhaustion in Wilson’s disease revealed by single-cell RNA sequencing predicts the prognosis of cholecystitis

   Yong Jin, Jiayu Xing ... Qingsheng Yu

   Metabolic abnormalities in hepatocytes cause the alteration of transcriptional profile and function of immune cells in the tissue microenvironment.
8. 1. Medicine
   2. Cancer Biology

   Monitoring of Cell-free Human Papillomavirus DNA in Metastatic or Recurrent Cervical Cancer: Clinical Significance and Treatment Implications

   Zhuomin Yin, Tao Feng ... Hanmei Lou
9. 1. Cell Biology
   2. Medicine

   Long non-coding RNA Malat1 fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and β-catenin-OPG/Jagged1 pathway

   Yongli Qin, Jumpei Shirakawa ... Baohong Zhao

   Malat1 is a key skeletal regulator, unveiling how lncRNAs integrate cellular crosstalk and molecular networks to regulate bone remodeling and regeneration, establishing a novel paradigm in tissue homeostasis and repair.
10. 1. Computational and Systems Biology
    2. Medicine

    Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations

    Xin Zhou, Zhinuo Jenny Wang ... Blanca Rodriguez

    Human-based electromechanical simulations reveal electrocardiogram biomarkers are better indicators of pro-arrhythmic substrate after myocardial infarction than ejection fraction.