Editors for Structural Biology and Molecular Biophysics

We aim to publish studies that advance our understanding of molecular mechanisms in biology, using experimental and computational approaches to provide quantitative insights. We also welcome studies describing structure determination by methods including cryoEM, crystallography and NMR, the investigation of macromolecular dynamics, the evolution of function and specificity in molecular systems, and the application of advanced biophysical methods to capture molecules in action. Read the latest research in this subject area.

Senior editors

  1. Richard Aldrich

    Richard Aldrich

    Senior Editor

    Rick Aldrich is the Karl Folkers Chair II in Interdisciplinary Biomedical Research and Professor of Neuroscience at The University of Texas at Austin. He joined the faculty in 2006 and served as chair until 2011. Previously he was on the faculty of Neurobiology (1985-1990) and of Molecular and Cellular Physiology (1990-2006) at Stanford University where he served as department chair from 2001–2004. He was an investigator with the Howard Hughes Medical Institute from 1990 to 2006. His work is on molecular mechanisms of ion channels and calcium signaling proteins, with an emphasis on understanding gated conformational changes and allosteric mechanisms. Work in the laboratory is multidisciplinary including electrophysiology, biochemistry, spectroscopy, informatics and computation. He is a member of the National Academy of Science and the American Academy of Arts and Sciences, and is a Fellow of the American Association for the Advancement of Science and of the Biophysical Society. He is past president of the Biophysical Society and the Society of General Physiologists, and has received the Kenneth Cole Award for Membrane Physiology from the Biophysical Society and Alden Spencer Award for Neuroscience Research from Columbia University.

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Research focus
    ion channels
    calcium binding proteins
    membrane transport
    allostery and cooperativity
    cellular neurophysiology
    biochemical neuroscience
    Competing interests statement
    Richard Aldrich is employed by The University of Texas at Austin. He receives research funding from the National Institutes of Health.He is a member of the National Academy of Science and the American Academy of Arts and Sciences, and is a Fellow of the American Association for the Advancement of Science and of the Biophysical Society. He serves actively on the editorial boards of Proceedings of the National Academy of Sciences and The Journal of General Physiology.
  2. John Kuriyan

    John Kuriyan

    Senior Editor

    John Kuriyan is Professor of Molecular and Cell Biology and also of Chemistry at the University of California, Berkeley. Before this, he was on the faculty at The Rockefeller University, New York, where he began his career in 1987, leaving for Berkeley in 2001. Since 1990, he has been an Investigator of the Howard Hughes Medical Institute. Kuriyan completed undergraduate studies in chemistry at Juniata College, Huntingdon, PA. His doctoral research, on the dynamics of proteins, was carried out at MIT, under the guidance of Greg Petsko and Martin Karplus (Harvard University). Kuriyan’s research is aimed at understanding the structure and mechanism of the enzymes and molecular switches that carry out cellular signal transduction and DNA replication. His laboratory uses x-ray crystallography to determine the three-dimensional structures of proteins involved in signaling and replication, as well as biochemical, biophysical, and computational analyses to elucidate mechanisms. Kuriyan was elected to the US National Academy of Sciences in 2001.

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    protein science and biochemistry
    signaling
    crystallography
    electron microscopy
    modeling
    molecular dynamics
    Competing interests statement
    John Kuriyan has received funding from the Howard Hughes Medical Institute, the US National Institutes of Health, and the Leukemia and Lymphoma Society. He serves on the editorial board of the Proceedings of the National Academy of Sciences, and on the Scientific Advisory Boards of Carmot Therapeutics (San Francisco) and Jubilant Biosys (Bangalore). He is a founder of Nurix (San Francisco).
  3. Andrea Musacchio

    Senior Editor

    Andrea Musacchio is Director of the Department of Mechanistic Cell Biology at the Max Planck Institute of Molecular Physiology in Dortmund (Germany) since 2011, and he is also adjunct professor at the University of Duisburg-Essen. Before this, he worked at the European Institute of Oncology in Milan (Italy), where he established his first laboratory as an independent investigator in 1999. Musacchio completed undergraduate studies at the University of Rome-Tor Vergata and moved for his graduate studies to the EMBL in Heidelberg, working under the guidance of Dr. Matti Saraste on the structural analysis of signalling domains. He later moved to do his postdoctoral training at the Harvard Medical School under the guidance of Prof. Stephen C. Harrison, working on structures of clathrin. Work in the Musacchio laboratory focuses on the biochemical reconstitution, structural analysis, and functional investigation of kinetochores and centromeres, structures required for chromosome segregation during mitosis. Musacchio is EMBO Member since 2009.

    Expertise
    Cell Biology
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    kinetochore
    cell cycle
    centromere
    Competing interests statement
    Andrea Musacchio receives funding from the Max Planck Society, the Deutsche Forschung Gemeinschaft, and the European Commission. He serves on the Editorial Boards of Current Biology, EMBO Reports, Chromosoma, Cell Research, Journal of Cell and Molecular Biology, Biology Open, and Journal of Structural Biology. He is a member of the Scientific Advisory Committee of the Armenise-Harvard Foundation.

Reviewing editors

  1. Lucy Forrest

    National Institute of Neurological Disorder and Stroke, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    protein structure prediction
    secondary active transporters
    membrane proteins
    molecular simulations
  2. Geeta Narlikar

    University of California, San Francisco, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    chromatin
    heterochromatin spread
    chromatin remodeling machines
  3. Jose Faraldo-Gomez

    National Heart, Lung and Blood Institute, National Institutes of Health, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    Computational biophysics
    molecular computation
    membrane proteins
  4. Leon D. Islas

    Universidad Nacional Autónoma de México, Mexico

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    molecular computation
    membrane proteins
    ion channels
    fluorescence
    models
  5. Yamuna Krishnan

    University of Chicago, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    nucleic acid-based molecular devices
    DNA machines
    chemical biology
    synthetic biology
    bioengineering
    Experimental organism
    C. elegans
  6. Arun Radhakrishnan

    UT Southwestern Medical Center, United States

    Expertise
    Biochemistry and Chemical Biology
    Cell Biology
    Structural Biology and Molecular Biophysics
    Research focus
    cholesterol sensors
    cholesterol transport
    endoplasmic reticulum
    Experimental organism
    E. coli
    human
    mouse
  7. Thomas Surrey

    The Francis Crick Institute, United Kingdom

    Expertise
    Structural Biology and Molecular Biophysics
    Cell Biology
    Research focus
    Microtubule cytoskeleton
    in vitro reconstitution
    Experimental organism
    human
  8. Patricia Bassereau

    Institut Curie, France

    Expertise
    Structural Biology and Molecular Biophysics
    Cell Biology
    Research focus
    membrane biophysics
    intracellular trafficking
    membrane shaping mechanisms
    biomimetic membrane systems
  9. Nir Ben-Tal

    Tel Aviv University, Israel

    Expertise
    Structural Biology and Molecular Biophysics
    Computational and Systems Biology
    Research focus
    structural bioinformatics
    structure, function and motion in membrane proteins
    protein interactions
  10. James Berger

    Johns Hopkins University School of Medicine, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    x-ray crystallography
    microscopy
    biochemistry
    biophysics
    DNA replication
    ATPase mechanism
    DNA topology
    topoisomerases
    helicases
  11. Richard M Berry

    University of Oxford, United Kingdom

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    rotary molecular motors
    bacterial flagellar motor
    ATPase mechanism
    single-molecule methods
    Experimental organism
    E. coli
  12. Pamela Bjorkman

    California Institute of Technology, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Immunology and Inflammation
    Research focus
    structural biology
    immunology
    HIV
  13. Olga Boudker

    Weill Cornell Medical College, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Research focus
    membrane transport
    glutamate pumps
  14. Axel T Brunger

    Stanford University, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Research focus
    structural biology
    synaptic transmission
    neurotransmitters
  15. Andrew Carter

    MRC Laboratory of Molecular Biology (Cambridge), United Kingdom

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    x-ray crystallography
    cryo-electron microscopy
    single-molecule methods
    structural studies of dynein
  16. Baron Chanda

    University of Wisconsin - Madison, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Research focus
    ion channels
    voltage-gating
    temperature-sensing
    ligand-gating
    allostery and dynamics
    single molecule studies
    fluorometry
  17. Lazlo Csanady

    Semmelweis University, Hungary

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    ion channels
    structure-function
    gating
    cftr
    ABC potein
    TPRM2
    Experimental organism
    E. coli
    human
    xenopus
  18. Volker Dötsch

    Goethe University, Germany

    Expertise
    Structural Biology and Molecular Biophysics
    Cell Biology
    Research focus
    membrane proteins
    signal transduction
  19. Edward Egelman

    University of Virginia, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    cryo-EM
    helicases
    Experimental organism
    E. coli
    viruses
  20. Paul G Falkowski

    Rutgers University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Ecology
    Research focus
    coral biology
    biogeochemical cycles
    biological oceanography
    evolution of photosynthesis
    physiological adaptation
    symbiosis
  21. Nikolaus Grigorieff

    Janelia Research Campus, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    cryo-EM
    image processing
  22. Taekjip Ha

    Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    single-molecule fluorescence spectroscopy and microscopy
  23. Franz-Ulrich Hartl

    Max Planck Institute of Biochemistry, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    protein folding
    molecular chaperones
    neurodegenerative disorders
  24. Manajit Hayer-Hartl

    Max Planck Institute of Biochemistry, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    molecular chaperones
    protein folding and assembly
    protein misfolding and aggregation
    molecular machines
  25. Reinhard Jahn

    Max Planck Institute for Biophysical Chemistry, Germany

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Research focus
    membrane proteins
    secretion
    synaptic transmission
  26. Frank Jülicher

    Max Planck Institute for the Physics of Complex Systems, Germany

    Expertise
    Structural Biology and Molecular Biophysics
    Physics of Living Systems
    Research focus
    active cellular processes
    physics of the cytoskeleton and motor proteins
    physics of cell division
    tissues and developmental processes
    ear and hearing
  27. Lewis Kay

    University of Toronto, Canada

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    NMR spectroscopy
    Experimental organism
    human
  28. Stephen C Kowalczykowski

    University of California, Davis, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Chromosomes and Gene Expression
    Research focus
    recombinational DNA repair
    single-molecule biophysics
    DNA-protein interactions
    Experimental organism
    E. coli
    S. cerevisiae
    human
  29. Werner Kuhlbrandt

    Max Planck Institute for Biophysics, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Cell Biology
    Research focus
    membrane protein structure and function
    membrane transporters
    macromolecular complexes
    molecular bioenergetics
    cryo-EM
  30. Richard Lewis

    Stanford University School of Medicine, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    ion channels
    signal transduction
  31. Andrei Lupas

    Max Planck Institute for Developmental Biology, Germany

    Expertise
    Computational and Systems Biology
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    origins and evolution of folded proteins
    coiled coils
    bioinformatics
    transmembrane signal tranduction
    bacterial surface proteins
  32. Andreas Martin

    University of California, Berkeley, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    AAA+ ATPases
    protein degradation
    ATPase mechanism
    protein folding
  33. Anna Pyle

    Yale University, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Immunology and Inflammation
    Research focus
    RIG-I like receptors
    innate immunity
    antiviral signaling
    helicases
    group II intron
    vaccine adjuvants
    RNA design
    computational modeling
    RNA structure
    Experimental organism
    human
    mouse
    viruses
  34. Samara L Reck-Peterson

    University of California San Diego, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Cell Biology
    Research focus
    microtubule-based motors
    intracellular transport
  35. Sjors HW Scheres

    Medical Research Council Laboratory of Molecular Biology, United Kingdom

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    microscopy
    molecular machines
  36. Yibing Shan

    DE Shaw Research, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Computational and Systems Biology
    Research focus
    computational structural biology
    signaling
    computational chemistry
    molecular dynamics
  37. Sriram Subramaniam

    National Cancer Institute, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Research focus
    cryo-electron microscopy
    protein structure
    HIV entry
    correlative light and electron microscopy
    electron tomography
    automated image processing
  38. Wesley Sundquist

    University of Utah, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Microbiology and Infectious Disease
    Research focus
    virus-host interactions
    retroviruses
    HIV
    Experimental organism
    human cells
  39. Kenton J Swartz

    National Institute of Neurological Disorders and Stroke, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Neuroscience
    Research focus
    ion channel structure and mechanisms
    mechanisms of toxins and drugs
    temperature-sensing
    lipid-protein interactions
  40. Antoine M van Oijen

    University of Wollongong, Australia

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    single-molecule biophysics
    protein-DNA interactions
    DNA replication
    DNA repair
  41. Clare M Waterman

    National Heart, Lung, and Blood Institute, National Institutes of Health, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Cell Biology
    Research focus
    actin cytoskeleton
    light microscopy
  42. Oliver Weichenrieder

    Max Planck Institute for Developmental Biology, Germany

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    retrotransposition
    regulatory mRNA
    x-ray crystallography
    structural biology
  43. William I Weis

    Stanford University, United States

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    cell adhesion
    wnt signaling
    x-ray crystallography
    structural biology
  44. Cynthia Wolberger

    Johns Hopkins University School of Medicine, United States

    Expertise
    Structural Biology and Molecular Biophysics
    Chromosomes and Gene Expression
    Research focus
    x-ray crystallography
    enzymology
    transcriptional regulation
    ubiquitin signaling
  45. Mingjie Zhang

    Hong Kong University of Science and Technology, Hong Kong SAR China

    Expertise
    Biochemistry and Chemical Biology
    Structural Biology and Molecular Biophysics
    Research focus
    structural biology
    neuronal development and signaling
    cell polarity
    scaffold proteins