Editors for Structural Biology and Molecular Biophysics
Senior editors
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Amy H Andreotti
Iowa State University, United States
Amy Andreotti is the Roy J Carver Chair in Biochemistry and a University Professor at Iowa State University. She joined the faculty of the Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology in 1997 after earning her PhD in Chemistry at Princeton University and completing a postdoctoral training period in the Chemistry Department at Harvard University where she was a Science Scholar at the Bunting Institute of Radcliffe College. Her work explores the mechanisms of kinase regulation during cell signaling with an emphasis on the immune specific TEC family of non-receptor tyrosine kinases. A particular focus of the lab is Bruton’s tyrosine kinase (BTK) and its interactions with small molecule therapeutics. Her lab uses a variety of biochemical, enzymatic and structural biology methods including solution NMR spectroscopy.
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- NMR spectroscopy
- kinase regulation
- cell signalling
- Tec family kinases
- Experimental organism
- human
- Competing interests statement
- Amy Andreotti's research is currently funded by the National Institutes of Health. She also serves on the National Advisory Committee for the Biomedical Scholars program of the Pew Charitable Trusts.
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Nancy Carrasco
Vanderbilt University School of Medicine, United States
Nancy Carrasco is the Joe C. Davis Professor and Chair of the Department of Molecular Physiology and Biophysics at the Vanderbilt University School of Medicine. She obtained her MD and Master’s in Biochemistry from the National Autonomous University of Mexico in her native Mexico City. Dr Carrasco did her postdoctoral work at the Roche Institute of Molecular Biology in New Jersey, for which she received a Fogarty International Fellowship. She then joined the Department of Molecular Pharmacology at the Albert Einstein College of Medicine, and later the Department of Cellular and Molecular Physiology at the Yale School of Medicine. Dr Carrasco has a longstanding interest in transport across biological membranes and in the role of membrane proteins in physiology and pathophysiology. Her cloning of the sodium/iodide symporter (NIS) has had numerous ramifications for many other fields, including structure/function of transport proteins, molecular endocrinology, gene transfer studies, cancer, and public health (she has served on the EPA’s Science Advisory Board). She has received numerous awards, including the Pew Award; the Arnold and Mabel Beckman Foundation Award; the Maria Sibylla Merian Award (Germany); the Merck Prize from the European Thyroid Association (Poland); the Rose Pitt-Rivers Lectureship at the British Endocrine Society Meeting (Scotland); the Noun Shavit Award (Israel); the Marshall S. Horwitz Faculty Prize for Research Excellence; and the Light of Life Award. She has served as president of the Society of Latin American Biophysicists. Dr Carrasco was elected to the National Academy of Sciences in 2015 and to the National Academy of Medicine in 2020.
- Expertise
- Medicine
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular endocrinology
- biochemistry of membrane proteins
- biophysics of membrane proteins
- mechanistic information of NIS
- regulation of NIS
- sodium/iodide symporter
- cross-talk between hormones
- metabolism
- Experimental organism
- mouse
- human
- Competing interests statement
- Dr Carrasco’s research has been funded by NIH. She is on the NICHD Board of Scientific Counselors.
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Qiang Cui
Boston University, United States
Qiang Cui is a professor of Chemistry at Boston University and also affiliated with the Departments of Physics and Biomedical Engineering. He received a B.S. in Chemical Physics from the University of Science and Technology of China in 1993, and a Ph.D. in Theoretical Chemistry in 1997 from Emory University under the tutelage of Professor Keiji Morokuma. He conducted postodctoral research with Professor Martin Karplus at Harvard University and, in 2001, moved to the University of Wisconsin, Madison, as a faculty member in the Chemistry department. After spending almost 17 wonderful years in Madison, he moved back to Boston in 2018. His current research interests include quantum chemistry and statistical mechanics and their applications to various chemical, biological, and materials problems.
Expertise: Computational biophysics, especially molecular dynamics, hybrid quantum mechanical/molecular mechanics simulations, free energy simulations applied to enzymes, biomolecular machines and lipid membranes.
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular dynamics
- hybrid quantum
- classical simulations
- enzyme catalysis
- allostery
- protein dynamics
- membrane remodeling
- Competing interests statement
- Qiang Cui currently serves as an associate editor for the Journal of Chemical Theory and Computation (American Chemical Society).
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Volker Dötsch
Goethe University, Germany
Volker Dötsch is Professor of Biophysical Chemistry at Goethe University and a member of the Magnetic Resonance Center Frankfurt. He studied chemistry at the University of Göttingen and obtained a PhD from the ETH in Zürich. As a postdoctoral fellow he used NMR to determine the structure of protein-DNA complexes at the Harvard Medical School. In 1998 he moved as assistant professor to the University of California San Francisco (UCSF). In 2003 he was appointed professor at the Institute of Biophysical Chemistry of Goethe University in Frankfurt. His research interests focus on the structural and functional characterization of members of the p53 protein family, in particular p63 and its involvement in genetic quality control in germ cells. In addition, his laboratory uses a combination of NMR spectroscopy and cell-free protein expression to investigate the structure and function of membrane proteins and studies molecular interactions regulating autophagy. His lab uses a wide variety of biophysical methods including NMR spectroscopy and combines these studies with investigations in cell culture experiments and mouse models. Volker Dötsch is an elected EMBO member.
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- p53 protein family
- cell-free expression and membrane protein structure and function
- autophagy
- Competing interests statement
- Volker Dötsch has received funding from the Deutsche Forschungsgemeinschaft, the National Institutes of Health and the Deutsche Krebshilfe. He is on the Scientific Advisory Board of the Frankfurt Institute of Advanced Studies and a member of the editorial boards of Journal of Biological Chemistry and Cell Death & Disease.
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Merritt Maduke
Stanford University School of Medicine, United States
Merritt Maduke is an Associate Professor of Molecular & Cellular Physiology and co-director of the Neurosciences Interdisciplinary Graduate Program at Stanford University School of Medicine. She received her PhD in Chemistry from the University of California, San Diego and did postdoctoral training at Brandeis University with Professor Chris Miller. Her research at Stanford is centered on the biophysics of ion channels and transporters, with the overarching goal of understanding molecular mechanisms within the context of physiological functions. She also applies her mechanistic approach in the field of ultrasound neuromodulation. She was awarded the Society of General Physiologist’s Cranefield Award for her research on ion channels (2008) and served as the Society’s President from 2018-2019.
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Biochemistry and Chemical Biology
- Research focus
- ion channel and transporter molecular mechanisms
- ion channel and transporter physiology
- ion channel and transporter pharmacology
- ultrasound neuromodulation
- Experimental organism
- E. coli
- mouse
- rat
- Competing interests statement
- Merritt Maduke is employed by Stanford University and receives research funding from the National Institutes of Health and Stanford Innovative Medicine Accelerator. She has served on the BPNS and BBM study sections at the NIH and as ad hoc member of additional panels. She serves on the editorial boards of the Biophysical Journal and The Journal of General Physiology and is a founding curator for Biophysics Colab.
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Kenton J Swartz
National Institute of Neurological Disorders and Stroke, NIH, United States
Kenton Swartz has been a Senior Investigator in the National Institute of Neurological Disorders and Stroke within the National Institutes of Health in Bethesda, Maryland since 2003. He obtained a BS in Chemistry and Biology from Eastern Mennonite College in 1986 and a PhD in Neurobiology from Harvard Medical School in 1993, where he worked with Bruce Bean studying the regulation of voltage-gated calcium channels by G-proteins and protein kinases. He obtained postdoctoral training with Roderick MacKinnon at Harvard Medical School, where he began isolating and studying toxins that interact with voltage-activated potassium channels. His laboratory uses biochemical, molecular biological, biophysical and structural techniques to understand how ion channel proteins sense critical biological stimuli, including membrane voltage, temperature, and both chemical and mechanical signals. He received an NIH Directors Award for Scientific Achievement in 2008, an NIH Office of the Director Honor Award on behalf of the Diversity Task Force in 2011 and the Kenneth S. Cole Award from the Biophysical Society in 2017. He has also served as the president of the Society of General Physiologists.
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Biochemistry and Chemical Biology
- Research focus
- ion channel structure
- ion channel mechanisms
- ion channel physiology
- ion channel pharmacology
- Experimental organism
- mouse
- Competing interests statement
- Kenton Swartz is employed by the Intramural Research Program of the National Institute of Neurological Disorders and Stroke, National Institutes of Health. In addition to serving as a Senior Editor at eLife, he has served as a Reviewing Editor for eLife and as an Associate Editor at the Journal of General Physiology. He also teaches yoga at LifeTime Athletic.
Reviewing editors
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Toby W Allen
RMIT University, Australia
- Expertise
- Structural Biology and Molecular Biophysics
- Physics of Living Systems
- Neuroscience
- Research focus
- computational biophysics
- molecular dynamics
- free-energy calculations
- ion channels
- ion permeation
- membranes
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Demet Araç
University of Chicago, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- G protein-coupled receptors (GPCR)
- synapse formation
- cell adhesion
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Patricia Bassereau
Institut Curie, France
- Expertise
- Cell Biology
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- physics of cells
- membrane biophysics
- mechanobiology
- intracellular traffic
- endocytosis
- adhesion
- cellular protrusions
- biomimetic membranes
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Kurt Beam
University of Colorado Anschutz Medical Campus, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Physics of Living Systems
- Research focus
- excitation-contraction coupling in skeletal muscle
- voltage-gated calcium channels
- calcium release channels
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Amie K Boal
Pennsylvania State University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- bioinorganic chemistry
- enzymes
- microbial chemistry
- x-ray crystallography
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Felix Campelo
The Institute of Photonic Sciences, Spain
- Expertise
- Physics of Living Systems
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- membrane mechanics
- membrane curvature
- intracellular trafficking
- membrane organization
- membrane contact sites
- Golgi complex
- endoplasmic reticulum exit sites
- super-resolution microscopy
- single-molecule microscopy
- Experimental organism
- human
- S. cerevisiae
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Henry M Colecraft
Columbia University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Cell Biology
- Research focus
- ion channels
- ion channel regulation
- voltage-gated calcium channels
- ubiquitin
- ion channelopathy
- Experimental organism
- human
- mouse
- rat
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Mauricio Comas-Garcia
Universidad Autónoma de San Luis Potosí, Mexico
- Expertise
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Research focus
- physical virology
- RNA packaging
- viral assembly
- virus-like-particle
- vaccines
- RNA viruses
- structural virology
- biophysics
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Laszlo Csanady
Semmelweis University, Hungary
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- ion channel structure-function
- CFTR
- TRPM2
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Lucie Delemotte
Science for Life Laboratory, Sweden
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- membrane proteins
- structural bioinformatics
- channelopathies
- computational biophysics
- free-energy calculations
- structure-function relationship
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Laura R Delgui
National Scientific and Technical Research Council, Argentina
- Expertise
- Cell Biology
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Research focus
- virus-host cell interactions
- membranes
- molecular biology
- cellular biology
- structural biology
- biophysics
- molecular dynamics
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David Drew
University of Stockholm, Sweden
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- membrane transporters
- x-ray crystallography
- cryo-EM
- membrane protein biotechnology
- bioenergetics
- solute carrier (SLC) transport
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Aaron Frank
Arrakis Therapeutics, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- molecular modeling
- biophysics
- structural biology
- computation
- RNA biochemistry
- RNA structural biology
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Adam Frost
University of California, San Francisco, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- cryo-EM
- electron cryo-microscopy
- membranes
- membrane remodeling
- proteostasis
- stress responses
- translation
- mitochondria
- nuclear envelope
- intracellular trafficking
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Teresa Giraldez
Universidad de La Laguna, Spain
- Expertise
- Neuroscience
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- neuronal excitability
- channelopathies
- Experimental organism
- mouse
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Marcel Goldschen-Ohm
University of Texas at Austin, United States
- Expertise
- Neuroscience
- Structural Biology and Molecular Biophysics
- Research focus
- ion channel structure and mechanisms
- single molecule dynamics
- single molecule fluorescence
- patch-clamp electrophysiology
- ligand binding
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Ruben Gonzalez
Columbia University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- translation
- translational control
- ribosomes
- RNA
- tRNA
- single-molecule biophysics
- single-molecule fluorescence resonance energy transfer
- cryo-EM
- biochemistry
- live cell imaging
- Experimental organism
- B. subtilis
- E. coli
- human
- S. cerevisiae
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Martin Graña
Institut Pasteur de Montevideo, Uruguay
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Evolutionary Biology
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- protein 3D structure
- structural bioinformatics
- structure/function relationships
- evolution
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Yogesh K Gupta
The University of Texas Health Science Center at San Antonio, United States
- Expertise
- Medicine
- Structural Biology and Molecular Biophysics
- Cancer Biology
- Microbiology and Infectious Disease
- Research focus
- drug discovery
- nucleic acid modifications
- cancer epigenetics
- structures of viral proteins
- host-pathogen interactions
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Shozeb Haider
University College London, United Kingdom
- Expertise
- Medicine
- Structural Biology and Molecular Biophysics
- Computational and Systems Biology
- Microbiology and Infectious Disease
- Research focus
- X-ray crystallography
- molecular dynamics simulations
- allostery
- structure-based drug design
- structural bioinformatics
- computational chemistry
- nucleic acids
- rare diseases
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Donald Hamelberg
Georgia State University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- molecular dynamics
- classical simulations
- protein dynamics
- protein allostery
- enzyme catalysis
- Long time scale dynamics
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Franz-Ulrich Hartl
Max Planck Institute of Biochemistry, Germany
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protein folding
- molecular chaperones
- neurodegenerative disorders
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Heedeok Hong
Michigan State University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- membrane proteins
- membrane protein folding
- membrane protein stability
- rhomboid proteases
- ATP-dependent proteolysis
- AAA+
- GlpG
- FtsH
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Leon D. Islas
Universidad Nacional Autónoma de México, Mexico
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- molecular computation
- membrane protein
- ion channels
- fluorescence
- models
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Andres Jara-Oseguera
University of Texas at Austin, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- ion channels
- Transient Receptor Potential (TRP) channels
- membrane transport proteins
- nociception
- voltage-activated channels
- cellular excitability
- pain-signaling
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Tatiana G Kutateladze
University of Colorado School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- epigenetics
- chromatin
- protein structure
- NMR spectroscopy
- molecular mechanisms
- Experimental organism
- human
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Joanne Lemieux
University of Alberta, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protease
- intramembrane protease
- crystallography
- membrane proteins
- structural biology
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Richard Lewis
Stanford University School of Medicine, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- calcium signaling
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Geeta Narlikar
University of California, San Francisco, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- chromatin
- heterochromatin spread
- chromatin remodeling machines
- phase-separation
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Mark T. Nelson
The University of Vermont, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- ion channels
- calcium signaling
- neurovascular coupling in the brain
- vascular, cell and systems biology
- Experimental organism
- mouse
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Hannes Neuweiler
University of Würzburg, Germany
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- protein folding
- protein dynamics
- protein engineering
- fluorescence spectroscopy
- fluorescence probes
- kinetics
- single-molecule fluorescence spectroscopy
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Rohit V Pappu
Washington University in St Louis, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Physics of Living Systems
- Research focus
- biophysics
- intrinsically disordered proteins
- intracellular phase transition phenomena
- organization of proteins and nucleic acids
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Stephan Pless
University of Copenhagen, Denmark
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- ion channels
- pharmacology
- electrophysiology
- biophysics
- chemical biology
- non-canonical amino acids
- protein engineering
- neurobiology
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Owen Pornillos
University of Virginia, United States
- Expertise
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- higher-order assembly
- cell-free reconstitution
- retrovirus structure
- tripartite motif proteins
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Murali Prakriya
Northwestern University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- cell imaging
- cellular electrophysiology
- calcium signaling
- ion channels
- neurobiology
- cell physiology
- Experimental organism
- mouse
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Arun Radhakrishnan
University of Texas Southwestern Medical Center, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- lipid sensors
- cholesterol
- sphingomyelin
- cholesterol transport
- SREBP
- Scap
- cholesterol homeostasis
- endoplasmic reticulum
- Experimental organism
- E. coli
- human
- mouse
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Marina V Rodnina
Max Planck Institute for Biophysical Chemistry, Germany
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- translation
- ribosomes
- tRNA
- translation fidelity
- cotranslational protein folding
- recoding
- translation factors
- translation regulation
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Rina Rosenzweig
Weizmann Institute of Science, Israel
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- NMR
- protein folding
- chaperones
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Jon T Sack
University of California, Davis, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- ion channels
- voltage gating
- voltage clamp electrophysiology
- ligand binding
- allostery
- rate theory modeling
- thermodynamics
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Ignacio E Sanchez
CONICET / Universidad de Buenos Aires, Argentina
- Expertise
- Computational and Systems Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular biophysics
- bioinformatics
- systems biology
- synthetic biology
- proteomics
- genomics
- metabolomics
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Rajan Sankaranarayanan
CSIR – Centre for Cellular and Molecular Biology, India
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- crystal structure
- mechanism
- translation of genetic code
- proofreading
- editing
- tRNA synthetase
- Experimental organism
- E. coli
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Sjors HW Scheres
Medical Research Council Laboratory of Molecular Biology, United Kingdom
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- cryo-EM
- maximum likelihood
- image processing
- amyloids
- tau
- alpha-synuclein
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Sang-Hee Shim
Korea University, South Korea
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- super-resolution optical microscopy
- in situ structural biology
- multiplexed microscopy
- spatial genome organization and dynamics
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Jungsan Sohn
Johns Hopkins University School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Immunology and Inflammation
- Microbiology and Infectious Disease
- Research focus
- innate immunity
- inflammasomes
- X-ray crystallography
- cryo-EM
- biochemistry
- enzyme kinetics
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Randy B Stockbridge
University of Michigan, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- transporters
- microbial membrane proteins
- crystallography
- electrophysiology
- Experimental organism
- E. coli
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Thomas Surrey
The Francis Crick Institute, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- cytoskeleton
- spindle assembly
- cell division
- motor proteins
- microtubules
- self-organization
- active networks
- Experimental organism
- human
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Alan Talevi
National University of La Plata, Argentina
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Research focus
- bioinformatics
- drug discovery
- cheminformatics
- pharmacy
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Ilaria Testa
KTH Royal Institute of Technology, Sweden
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- super resolution microscopy
- STED
- RESOLFT
- SIM
- Single-molecule
- fluorescence
- photochromic probes
- light microscopy
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Mohamed Trebak
University of Pittsburgh School of Medicine, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Cell Biology
- Biochemistry and Chemical Biology
- Research focus
- calcium channels
- receptor signalling
- ion channel regulation
- vascular remodeling
- smooth muscle
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Julie P I Welburn
University of Edinburgh, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- mitosis
- cytoskeleton
- motors
- phosphorylation
- kinase
- microtubule
- cilia
- kinetochore
- Experimental organism
- human
- in vitro
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Jie Xiao
Johns Hopkins University, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Chromosomes and Gene Expression
- Microbiology and Infectious Disease
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- single molecule biophysics
- microbiology
- cell division
- cell wall
- gene expression
- Experimental organism
- E. coli
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Lejla Zubcevic
University of Kansas Medical Center, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- membrane transport
- structural biology
