Structural Biology and Molecular Biophysics

Structural Biology and Molecular Biophysics

eLife publishes research that uses techniques including X-ray crystallography, cryo-EM and single-molecule methods. Decisions are made by journal editors who are active researchers in structural biology and molecular biophysics.

Latest articles

    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Lateral interactions between protofilaments of the bacterial tubulin homolog FtsZ are essential for cell division

    Fenghui Guan et al.
    Structural and functional approaches unambiguously revealed physiologically relevant lateral interactions between FtsZ protofilaments.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor

    Kathryn E Livingston et al.
    Opioid drug efficacy and allosteric modulation is measured using an active state sensor of the mu-opioid receptor.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Microtubules soften due to cross-sectional flattening

    Edvin Memet et al.
    A combination of experiments, theory, and simulations shows that the elastic softening of microtubules when they are bent arises due to the flattening of their tubular cross-section.
    1. Structural Biology and Molecular Biophysics

    Valid molecular dynamics simulations of human hemoglobin require a surprisingly large box size

    Krystel El Hage et al.
    Simulations of the unliganded human hemoglobin tetramer, which for the first time yield a thermodynamically stable system, cast doubts on the use of standard solvent box sizes for molecular dynamics studies of biological macromolecules.
    1. Structural Biology and Molecular Biophysics

    An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering

    Daniel A Keedy et al.
    By measuring how multiple conformations shift in response to temperature, a new allosteric binding site is discovered for the phosphatase PTP1B.

Senior editors

  1. Richard Aldrich
    Richard Aldrich
    Senior Editor
  2. John Kuriyan
    John Kuriyan
    Senior Editor
  3. Andrea Musacchio
    Senior Editor
  4. See more editors