Structural Biology and Molecular Biophysics

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Multiple modes of cholesterol translocation in the human Smoothened receptor

   Prateek Bansal, Maia Kinnebrew ... Diwakar Shukla
2. 1. Structural Biology and Molecular Biophysics
   2. Computational and Systems Biology

   Unraveling the Molecular Mechanisms of ABHD5 Membrane Targeting

   Amit Kumar, Matthew Sanders ... Yu-ming M Huang
3. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

   Takashi Hotta, Morgan L Pimm ... Kristen J Verhey

   Three newly developed biosensors demonstrate that the C-terminal tail of α-tubulin does not freely extend from the microtubule surface as widely thought, but rather is inaccessible along most microtubules in cells.
4. 1. Structural Biology and Molecular Biophysics

   Receptor Proteins: Lipids challenge ligands to control receptors

   Adam JM Wollman

   The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.
5. 1. Medicine
   2. Structural Biology and Molecular Biophysics

   Medical Imaging: MRI sets its sights on collagen

   Fritz Schick

   Reducing the echo time of a whole-body MRI scanner makes it possible to image collagen, an important structural protein found in bones and tendons.
6. 1. Structural Biology and Molecular Biophysics

   Conformational Changes of the ABC Transporter BmrA Depend on Membrane Curvature

   Alicia Damm, Kemil Belhadji ... Patricia Bassereau
7. 1. Structural Biology and Molecular Biophysics

   In silico design and validation of high-affinity RNA aptamers for SARS-CoV-2 comparable to neutralizing antibodies

   Yanqing Yang, Lulu Qiao ... Ruhong Zhou
8. 1. Structural Biology and Molecular Biophysics

   In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles

   Zahra Seraj, Ximena Zottig ... Andrei A Korostelev
9. 1. Structural Biology and Molecular Biophysics

   Allosteric effects of the coupling cation in melibiose transporter MelB

   Parameswaran Hariharan, Yuqi Shi ... Lan Guan

   Intrinsic conformational flexibility of a solute transporter is restrained by substrates, resulting in Na+ allosterically enhancing primary substrate binding through cooperative constraints on the dynamics of the cytoplasmic inner barrier.
10. 1. Structural Biology and Molecular Biophysics

    Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty acyltransferase

    Wenjie W Zeng, Garrison Komaniecki ... Yuxin Mao

    A novel F-actin-binding motif consisting of an α-helix hairpin from a Legionella pneumophila lysine fatty acyltransferase has the potential to be developed as an F-actin probe.