Meta-Research: The changing career paths of PhDs and postdocs trained at EMBL

  1. Junyan Lu
  2. Britta Velten
  3. Bernd Klaus
  4. Mauricio Ramm
  5. Wolfgang Huber
  6. Rachel Coulthard-Graf  Is a corresponding author
  1. Genome Biology Unit, European Molecular Biology Laboratory, Germany
  2. EMBL International Centre for Advanced Training, European Molecular Biology Laboratory, Germany
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5 figures, 3 tables and 3 additional files

Figures

Figure 1 with 3 supplements
Career outcomes for EMBL alumni.

(A) Charts showing the percentage of PhD alumni (n=969) and postdoc alumni (n=1315) from EMBL in different careers in 2021 (see Table 1). (B) Charts showing percentage of PhD (left, n=800) and …

Figure 1—figure supplement 1
Sankey diagrams showing movement between different careers.

(A) Sankey diagram showing that of the 539 alumni who have held an Academia: PI (AcPI) position at some time, 75.3% moved into their first AcPI position from an Academia: Postdoc (AcPD) position, …

Figure 1—figure supplement 2
Career outcomes for EMBL alumni at five different time points for three different cohorts.

Charts showing the percentage of PhD and postdoc alumni in different roles at five different time points for three different cohorts. See Table 3 for cohort sizes; alumni who have not yet reached a …

Figure 1—figure supplement 3
Comparing EMBL alumni with alumni from institutions in Canada and the United States.

Charts comparing percentage of PhD alumni in PI or PI-like positions for EMBL and Stanford University, the University of California San Francisco (UCSF), the University of Chicago (Bioscience …

Figure 2 with 1 supplement
Changes in career outcomes for more recent cohorts.

(A) Kaplan–Meier plots showing the estimated probability of an individual being in a PI position (y-axis) as a function of time after EMBL (x-axis) for three cohorts of PhD alumni (left) and three …

Figure 2—figure supplement 1
Length of time taken to become a PI.

(A) Box plot with overlaid dot plot showing the distribution of the length of time between PhD and first PI role for two cohorts of alumni who defended their PhD between 1997 and 2012 and became a …

Figure 3 with 2 supplements
Gender differences in career outcomes.

(A) Charts showing the percentage of female (n=415) and male (n=554) PhD alumni, and female (n=492) and male (n=823) postdoc alumni, in different careers in 2021. (B) Kaplan–Meier plots showing the …

Figure 3—figure supplement 1
Length of time taken to become a PI for female and male alumni.

(A) Box plot with overlaid dot plot showing the distribution of the length of time between PhD and first PI role for female alumni (left) and male alumni (right) who defended their PhD between 1997 …

Figure 3—figure supplement 2
Rate of entry into different types of role by gender.

(A) Kaplan–Meier plots showing the estimated probability of an individual working in Academia: Other (y-axis) as a function of time after EMBL, stratified by gender for PhD alumni (left) and postdoc …

Figure 4 with 2 supplements
Publication factors are highly correlated with becoming a PI.

(A) Histograms showing the number of alumni who have 0, 1, 2, 3,... first-author articles from their time at EMBL and became PIs (bottom; n=662, excluding 23 outliers), and did not become PIs (top; …

Figure 4—figure supplement 1
Cox models for predicting entry into various careers.

Harrell’s C-Index for various Cox models for predicting entry into Academia: Other (A), Industry Research (B), Science-related Non-research (C), and Non-science-related careers (D). As in Figure 4D, …

Figure 4—figure supplement 2
Entry into various careers and number of first-author publications.

Kaplan–Meier plots showing the estimated probability of an individual being in various careers (y-axis) as a function of time after EMBL (x-axis), stratified by number of first-author publications …

Publications are increasingly collaborative.

(A) Mean number of authors (y-axis) as a function of year (x-axis) for research articles that were published between 1995 and 2020, and have at least one of the alumni included in this study as an …

Tables

Table 1
Career outcomes for 2284 EMBL alumni.
CareerPhD alumniPostdocTotal
Academia: PI (AcPI)215 (22.2%)421 (32%)636 (27.8%)
Academia: Other (AcOt)102 (10.5%)281 (21.4%)383 (16.8%)
Academia: Postdoc (AcPD)168 (17.3%)76 (5.8%)244 (10.7%)
Industry research (IndR)153 (15.8%)179 (13.6%)332 (14.5%)
Science-related Non-research (SciR)178 (18.4%)171 (13%)349 (15.3%)
Non-science-related (NonSci)47 (4.9%)44 (3.3%)91 (4%)
Unknown106 (10.9%)143 (10.9%)249 (10.9%)
TOTAL96913152284
  1. See Table 2 for more information on the different jobs covered by Industry Research, Science-related Non-research, and Non-science-related. This classification is based on Stayart et al., 2020.

  2. AcPI: includes those leading an academic research team with financial and scientific independence – evidenced by a job title such as group leader, professor, associate professor or tenure-track assistant professor. Where the status was unclear from the job title, we classified an alumnus as a Principal Investigator (PI) if one of the following criteria was fulfilled: (a) they appear to directly supervise students/postdocs (based on hierarchy shown on website); (b) they have published a last author publication from their current position; (c) their group website or CV indicates that they have a grant (not just a personal merit fellowship) as a principal investigator. AcOt: differs from Stayart et al., 2020 in that it includes academic research, scientific services or teaching staff (e.g., research staff, teaching faculty and staff, technical directors, research infrastructure engineers).

Table 2
Classification of Industry Research, Science-related Non-research and Non-science-related positions.
Job functionPhD alumniPostdocTotal
Industry research
R & D scientist*138 (14.2%)167 (12.7%)305 (13.4%)
Entrepreneurship6 (0.6%)8 (0.6%)14 (0.6%)
Postdoctoral7 (0.7%)1 (0.1%)8 (0.4%)
Business development, consulting & strategic alliances 2 (0.2%)3 (0.2%)5 (0.2%)
Total153 (15.8%)179 (13.6%)332 (14.5%)
Science-related Non-research
Administration and training35 (3.6%)35 (2.7%)70 (3.1%)
Business development, consulting & strategic alliances38 (3.9%)20 (1.5%)58 (2.5%)
Tech support and product development20 (2.1%)24 (1.8%)44 (1.9%)
Science writing and communication16 (1.7%0)21 (1.6%)37 (1.6%)
Data science, analytics, software engineering §15 (1.5%)13 (1%)28 (1.2%)
Intellectual property and law16 (1.7%)10 (0.8%)26 (1.1%)
Science education and outreach10 (1%)11 (0.8%)21 (0.9%)
Clinical research management8 (0.8%)4 (0.3%)12 (0.5%)
Regulatory affairs5 (0.5%)7 (0.5%)12 (0.5%)
Clinical services/public health4 (0.4%)6 (0.5%)10 (0.4%0)
Sales and Marketing4 (0.4%)6 (0.5%)10 (0.4%)
Healthcare provider1 (0.1%)8 (0.6%)9 (0.4%)
Other4 (0.4%)2 (0.2%)6 (0.3%)
Entrepreneurship2 (0.2%)2 (0.2%)4 (0.2%)
Science policy and government affairs0 (0%)2 (0.2%0)2 (0.1%)
Total178 (18.4%)171 (13%)349 (15.3%)
Non-science-related
Data science, analytics, software engineering §18 (1.9%)25 (1.9%)43 (1.9%)
Business development, consulting & strategic alliances16 (1.7%)4 (0.3%)20 (0.9%)
Other (inc retired)7 (0.7%)12 (0.9%)19 (0.8%)
Entrepreneurship5 (0.5%)2 (0.2%)7 (0.3%0)
Administration and training1 (0.1%)1 (0.1%)2 (0.1%)
Total47 (4.9%)44 (3.3%)91 (4%)
  1. *

    This function differs from the schema in Stayart et al., 2020; it includes alumni carrying out or overseeing scientific research in industry as group leaders, research staff, technical directors and non-directorship research leadership roles, including alumni who appear to be working in computational biology roles of a pharma, biotech, contract research or similar company regardless of job title (i.e. including data science roles that appear to be related to analysis of research-related data.)

  2. Founders of companies whose primary focus is R&D (including contract research organizations).

  3. Includes director-level senior management roles overseeing the scientific direction & research of a company with R&D focus, e.g. CSOs in biotech start-ups.

  4. §

    Not including computational biology roles linked to R&D functions.

Table 3
Overview of PhD and postdoc cohorts.
Completion yearsPhD cohortsPostdoc cohortsAll
1997–20042005–20122013–20201997–20042005–20122013–2020All
n =2563413723694225242284
n (%) known current role225 (88%)306 (90%)332 (89%)336 (88%)364 (86%)472 (90%)2035 (89%)
n (%) detailed career path220 (70%)258 (79%)413 (77%)179 (60%)271 (61%)285 (79%)1626 (71%)
n (%) female85 (33%)157 (46%)173 (47%)136 (37%)149 (35%)207 (40%)907 (40%)

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