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eLife is making changes to its policies on peer review in response to the impact of COVID-19 on the scientific community.

As he prepares to step down as the Editor-in-Chief of eLife, Randy Schekman reflects on the origins of the journal, the eLife approach to peer review, and current challenges in scientific publishing.

eLife is conducting a trial in which authors will decide how to respond to the issues raised during peer review.

Journals can benefit from listening to graduate students, postdocs and newly-independent group leaders.

Five years after eLife published its first papers, we reflect on our consultative approach to peer review, the challenges of reproducibility, and the need to reform how published research is assessed.

Authors submitting a manuscript to eLife are encouraged to upload it to a recognized preprint server at the same time in order to make their results available as quickly and as widely as possible.

To support the long-term growth of eLife we are going to introduce a publication fee of $2500.

Manuscripts should include all the experimental and statistical details that are needed to replicate the experiments and analyses reported in them.

The best papers provide evidence that can be used to make changes that improve the health and lives of people around the world.