AI in Science: The 42 problem in AI-assisted research

  1. Giovanni Spitale  Is a corresponding author
  2. Federico Germani
  1. ITE Lab, Institute of Biomedical Ethics and History of Medicine, University of Zurich, Switzerland
  2. Institute for Data Science and Artificial Intelligence, Boğaziçi University, Turkiye
1 figure

Figures

The value of a synthesis is not monotonic in its compression.

(A) As the length L of a synthesis falls, recovery R(L) declines from saturation, while the reading cost C(L) falls steadily, so that value initially rises. This is the case for automated synthesis, and within this range it is correct. Usability U(L) holds near one until L crosses the threshold L*, below which the text no longer carries the conditions that make its claims valid, and V(L)=R(L)·U(L)/C(L) collapses. (B) The position of L* is set by the question and the reader, not by the text: the same synthesis sits above the cliff for a screening decision and below it for a clinical guideline. Links do not raise the curve; they displace context rather than destroying it, moving L* to the left and extending the range over which compression remains safe.

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  1. Giovanni Spitale
  2. Federico Germani
(2026)
AI in Science: The 42 problem in AI-assisted research
eLife 15:e113137.
https://doi.org/10.7554/eLife.113137