2 figures

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Figure 1 with 1 supplement
Shisa7 is a type-I transmembrane protein interacting with AMPA-type receptors.

d) Biochemical fractionation (homogenate (H), crude synaptic membranes (P2; with and without microsomes (M)), synaptosomes (SS), synaptic membranes (SM) and postsynaptic density fraction (PSD; Triton X-100 insoluble fraction) of mature mouse hippocampus reveals an enrichment of Shisa7 in the PSD together with GluA2, GluN2B, PSD-95, and this pattern is distinct from the presynaptic marker Synaptophysin (Syp).

Figure 1—figure supplement 3
Figure 4 with 1 supplement
Figure 4—figure supplement 1

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  1. Leanne J M Schmitz
  2. Remco V Klaassen
  3. Marta Ruiperez-Alonso
  4. Azra Elia Zamri
  5. Jasper Stroeder
  6. Priyanka Rao-Ruiz
  7. Johannes C Lodder
  8. Rolinka J van der Loo
  9. Huib D Mansvelder
  10. August B Smit
  11. Sabine Spijker
(2018)
Correction: The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory
eLife 7:e36711.
https://doi.org/10.7554/eLife.36711