Neuroscience

Neuroscience

eLife publishes research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    A parameter-free statistical test for neuronal responsiveness

    Jorrit S Montijn et al.
    A simple and robust statistical test for neuronal stimulus response, that outperforms PSTH-based approaches such as t-tests and ANOVAs.
    1. Neuroscience

    Whole-brain connectivity atlas of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei

    Zhengchao Xu et al.
    Whole-brain quantitative input-output circuits of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei were mapped using viral tracing and high-resolution optical imaging.
    1. Neuroscience

    A conserved neuropeptide system links head and body motor circuits to enable adaptive behavior

    Shankar Ramachandran et al.
    Investigation of neuromodulatory control of ethologically conserved area-restricted food search behavior shows that NLP-12 stimulation of the head motor circuit promotes food searching through the previously uncharacterized CKR-1 GPCR.
    1. Medicine
    2. Neuroscience

    Science Forum: Consensus-based guidance for conducting and reporting multi-analyst studies

    Balazs Aczel et al.
    Using multiple analysts to independently analyze the same dataset has the potential to explore and strengthen the robustness of results and conclusions in basic and applied research.
    1. Neuroscience

    Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons

    Minh Q Nguyen et al.
    Single-nucleus transcriptomics exposes unique features of human somatosensory neurons and clues that may help resolve repeated problems in translating new experimental approaches for treating pain.
    1. Neuroscience

    Metabolomic profiling reveals a differential role for hippocampal glutathione reductase in infantile memory formation

    Benjamin Bessières et al.
    Hippocampal metabolomic analyses following episodic learning at different ages revealed a critical role for neuronal glutathione reductase activity in long-term infantile memory formation.
    1. Neuroscience

    Attention network modulation via tRNS correlates with attention gain

    Federica Contò et al.
    Parietal noninvasive brain stimulation during perceptual training causes a dramatic increase in learning that correlates with network-wide changes in functional connectivity, demonstrating the stimulation-induced physiological mechanisms leading to cognitive benefits.
    1. Neuroscience

    Circuits for integrating learned and innate valences in the insect brain

    Claire Eschbach et al.
    Electron-microscopy reconstruction and experimental investigation in Drosophila reveal how adaptive action emerges from the multi-level interactions between the output of the olfactory memory center and the innate olfactory pathway.
    1. Neuroscience

    Subpopulations of neurons in lOFC encode previous and current rewards at time of choice

    David L Hocker et al.
    A distinct subpopulation of neurons in the rat orbitofrontal cortex encodes reward history at the time of choice, providing a potential neural substrate by which reward history may influence decisions.
    1. Neuroscience

    Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

    Austin R Graves et al.
    A knockin mouse line was made to label endogenous AMPA receptors, enabling direct observation of synaptic plasticity in behaving animals with single-synapse resolution across the entire brain.

Highlights

    1. Neuroscience

    Decoding the infrastructure of the cerebellum

    Willem S van Hoogstraten, Chris I De Zeeuw

Senior editors

  1. Timothy Behrens
    University of Oxford, United Kingdom
  2. Claude Desplan
    New York University, United States
  3. Gary Westbrook
    Vollum Institute, United States
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