Neuroscience

Latest articles

1. 1. Neuroscience

   A critical re-evaluation of fMRI signatures of motor sequence learning

   Eva Berlot et al.

   A systematic assessment of previously proposed fMRI metrics of motor sequence learning reveals widespread activity reductions and subtle multivariate pattern changes outside of primary motor cortex.
2. 1. Developmental Biology
   2. Neuroscience

   Transverse sinus injections drive robust whole-brain expression of transgenes

   Ali S Hamodi et al.

   A new viral injection method targets the transverse sinuses to achieve robust whole-brain delivery of single or multiple genes in multiple mammalian species early in development.
3. 1. Neuroscience

   Dopaminergic modulation of the exploration/exploitation trade-off in human decision-making

   Karima Chakroun et al.

   Dopamine attenuates exploration during decision-making via a reduction of neural tracking of uncertainty.
4. 1. Neuroscience

   Hyperalignment: Modeling shared information encoded in idiosyncratic cortical topographies

   James V Haxby et al.

   Hyperalignment provides a conceptual framework for cortical architecture that captures how shared information is encoded in idiosyncratic cortical topographies that preserve vector geometry for population response and connectivity patterns.
5. 1. Neuroscience

   Temperature compensation in a small rhythmic circuit

   Leandro M Alonso, Eve Marder
6. 1. Neuroscience

   A Bayesian and efficient observer model explains concurrent attractive and repulsive history biases in visual perception

   Matthias Fritsche et al.
7. 1. Neuroscience

   MeCP2 in cholinergic interneurons of nucleus accumbens regulates fear learning

   Ying Zhang et al.

   Robust fear learning deficits and decreased tonic activity of NAc cholinergic interneurons caused by depletion of MeCP2 could be attributed to an elevation in α2-containing GABA_A receptors.
8. 1. Neuroscience

   Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury

   Matthew Grove et al.

   YAP and TAZ, potent concoproteins and therapeutic targets in cancer therapy, are essential for Schwann cells to support peripheral nerve regeneration.
9. 1. Neuroscience

   Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults

   Alexandra N Trelle et al.

   The strength of pattern completion during memory retrieval, indexed by hippocampal activity and cortical reinstatement, explains within- and across-individual variability in episodic memory in older adults.
10. 1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Disease-associated mutations in the human TRPM3 render the channel overactive via two distinct mechanisms

    Siyuan Zhao et al.

    Disease-associated mutants of the TRPM3 ion channel are overactive, and they are inhibited by the antiepileptic medication primidone, offering a potential therapeutic intervention to treat this channelopathy.