Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Effort Drives Saccade Selection

    Damian Koevoet, Laura Van Zantwijk ... Christoph Strauch
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation

    Tanya Wolff, Mark Eddison ... Gerald M Rubin
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

    Ulrike Pech, Jasper Janssens ... Patrik Verstreken
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Mechanism that regulates the mutual inhibition controls functional switch of UNC-13

    Haowen Liu, Lei Li ... Zhitao Hu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    The Neural Correlates of Novelty and Variability in Human Decision-Making under an Active Inference Framework

    Shuo Zhang, Yan Tian ... Haiyan Wu
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants

    Balázs István Tóth, Bahar Bazeli ... Thomas Voets
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Neurodegeneration: A role for RNA knots in Alzheimer’s disease

    Silvia Galli, Marco Di Antonio
    The buildup of knot-like RNA structures in brain cells may be the key to understanding how uncontrolled protein aggregation drives Alzheimer’s disease.
    Version of Record
    Insight
    1. Neuroscience

    Adaptive chunking improves effective working memory capacity in a prefrontal cortex and basal ganglia circuit

    Aneri Soni, Michael J Frank
    This frontostriatal neural network model links the source of working memory capacity limitations to challenges in learning resource management, and mitigates this challenge by learning a 'chunking' strategy.
    1. Neuroscience

    An image-computable model of speeded decision-making

    Paul I Jaffe, Gustavo X Santiago-Reyes ... Russell A Poldrack
    Combining biologically-plausible neural network models of vision with traditional decision-making models enables a detailed characterization of how the visual system extracts representations that guide decisions from raw sensory inputs.
    1. Neuroscience

    Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

    Hans Martin Kjer, Mariam Andersson ... Tim B Dyrby
    Common principles of white matter microstructure and pathway organisation was revealed using diffusion MRI and x-ray synchrotron imaging across resolutions, and employing diffusion tensor, micro-tensor, multi-fiber, and structure tensor models.

Highlights

    1. Developmental Biology
    2. Neuroscience

    Watching axons on the move

    Maria I Lazaro-Pena, Carlos A Diaz-Balzac

Senior editors

  1. Timothy Behrens
    University of Oxford / University College London, United Kingdom
  2. Merritt Maduke
    Stanford University School of Medicine, United States
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors