Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience
    2. Physiology

    Fitness Level, but not Sex, affects Exercise-Induced Pain Modulation

    Janne I Nold, Tahmine Fadai ... Christian Büchel
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Striatal dopamine and serotonin release operate largely in parallel with limited, asymmetric crosstalk

    Fabrice Chaudun, Yu Liu ... Christian Lüscher
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Convincing
    1. Neuroscience

    Reduced dorsal CA1 activity limits retention of the temporal component of declarative memory in the Cntnap2 knockout mouse model of autism

    Elise Caitlin Rawlinson, Michael Hugh McCullough ... Nathalie Dehorter
    Restoring hippocampal CA1 activation during temporal gaps is sufficient to rescue long-term memory in a mouse model of autism.
    1. Neuroscience

    Designing optimal perturbation inputs for system identification in neuroscience

    Mikito Ogino, Daiki Sekizawa ... Masafumi Oizumi
    Passive recordings miss patterns of brain activity that fade before they can be observed, but perturbations designed to re-excite those patterns make estimates of neural connections far more accurate.
    1. Cell Biology
    2. Neuroscience

    Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly

    Katherine X Dong, Yanbo Zhang ... Colleen N McLaughlin
    Systematic dissection of Rab GTPase function in developing neurons reveals that early and recycling endosome-associated Rabs regulate largely distinct aspects of neuronal morphogenesis and circuit assembly across developmental time.
    1. Neuroscience

    A framework for analyzing global Caenorhabditis elegans neural activity

    Iulia Rusu, Zachary T Cecere ... Sreekanth H Chalasani
    Computational and theoretical analyses reveal that Caenorhabditis elegans whole-brain activity can be represented in an 8-dimensional hyperbolic manifold that hierarchically links sensory ON/OFF inputs to motor states, providing a compact geometric framework for how a nervous system processes sensory information.
    1. Neuroscience
    2. Computational and Systems Biology

    A theory-guided model maps four recurrent modes of fear-goal arbitration across learning and relapse in rats

    Bin Yin, Jiaojiao Rao, XT (XiaoTian) Wang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Spatiotemporal Dissociation of Human Amygdala Response to Negative Affect

    Ke Bo, Martin A Lindquist ... Tor D Wager
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Synaptic vesicle undocking induces low-frequency depression

    Melissa Silva, Federico F Trigo ... Alain Marty
    Low-frequency depression, an understudied form of synaptic plasticity, is proposed to reflect a reorganization of synaptic vesicles inside the readily releasable pool.
    1. Neuroscience

    Robust and replicable effects of ageing on resting-state brain electrophysiology measured with MEG

    Andrew J Quinn, Jemma Pitt ... Mark W Woolrich
    Resting-state MEG reveals a replicable, full-frequency profile of ageing that offers a foundation for comparing and validating brain health biomarkers although detecting specific effects requires careful consideration of statistical power.

Senior editors

  1. Christian Büchel
    University Medical Center Hamburg-Eppendorf, Germany
  2. Lu Chen
    Stanford University, United States
  3. Jonathan Roiser
    University College London, United Kingdom
  4. See more editors