eLife publishes research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Decisions are made by journal editors who are active researchers in neuroscience.
The cerebellum encodes self-generated head rotations in a head posture-dependent manner, providing in particular a representation of how the head rotates about axes referenced relative to gravity.
Electrically active axons in white matter stimulate their own myelination by releasing glutamate, which signals through AMPA-type glutamate receptors on nearby oligodendrocyte precursors and newly-differentiating oligodendrocytes, enhancing their survival and hence their ability to myelinate.
The WorMotel, a novel microfabricated device for automated longitudinal imaging of aging in large numbers of Caenorhabditis elegans, reveals that long and short lived strains vary in their behavioral decline during aging in a similar way to the long and short lived individuals in a wild type population.
A comparison between hierarchical and flat models of decision-making refutes flat models because they lack flexibility and are not supported by behavioral and neural data.
Computational modeling of behavioral and neural data from monkeys points towards a flat decision-making process in which the brain considers all possible final outcomes simultaneously.
Activating ASIC channels in the amygdala makes a single reminder more effective at rendering consolidated fear memories labile and susceptible to modification.
Loss of MeCP2 function negatively impacts Tet1 and CTCF binding thereby negatively impacting learning-dependent DNA methylation and alternative splicing regulation.
