Neuroscience

Latest articles

1. 1. Neuroscience

   Untangling stability and gain modulation in cortical circuits with multiple interneuron classes

   Hannah Bos, Christoph Miehl ... Brent Doiron

   In recurrently connected cortical networks with different inhibitory neuron subtypes, circuit modulations can increase neuronal gain without compromising network stability.
2. 1. Neuroscience

   Neural substrates of cold nociception in Drosophila larva

   Atit A Patel, Albert Cardona, Daniel N Cox
3. 1. Neuroscience

   A multiplex of connectome trajectories enables several connectivity patterns in parallel

   Parham Mostame, Jonathan Wirsich ... Sepideh Sadaghiani
4. 1. Immunology and Inflammation
   2. Neuroscience

   Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline

   Jeremy M Shea, Saul A Villeda

   During aging, microglia progress through intermediate cellular states, including stress response and translation upregulation states, that modulate subsequent activation and impact cognitive decline.
5. 1. Neuroscience

   A toolbox for ablating excitatory and inhibitory synapses

   Aida Bareghamyan, Changfeng Deng ... Don B Arnold

   Novel genetically encoded tools PFE3, paGFE3, and chGFE3 can be used to reversibly ablate excitatory synapses constitutively, and inhibitory synapses in a light- or chemically dependent manner.
6. 1. Neuroscience

   Leveraging place field repetition to understand positional versus nonpositional inputs to hippocampal field CA1

   William Hockeimer, Ruo-Yah Lai ... James J Knierim

   Place cells that show repeating place fields in geometrically similar locations of an environment modulate their firing rates differently in each field based on movement direction.
7. 1. Neuroscience

   Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair

   Patricia E Phelps, Sung Min Ha ... Xia Yang

   To better understand how olfactory ensheathing cells modify spinal cord injury sites, single-cell RNA-sequencing was used to identify five OEC subtypes, progenitors, and novel genes associated with axonal outgrowth.
8. 1. Neuroscience

   Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia

   Nguyet Le, Sherine Awad ... Seth Blackshaw
9. 1. Neuroscience

   Rhythmic circuit function is more robust to changes in synaptic than intrinsic conductances

   Zachary Fournier, Leandro M Alonso, Eve Marder

   Modifications of the intrinsic currents in neuronal circuits are more likely to result in loss of function than changes in synaptic strength.
10. 1. Neuroscience

    Cholecystokinin modulates age-dependent Thalamocortical Neuroplasticity

    Xiao Li, Jingyu Feng ... Jufang He