Neuroscience

Latest articles

1. 1. Medicine
   2. Neuroscience

   APOE2 is associated with longevity independent of Alzheimer’s disease

   Mitsuru Shinohara et al.

   Translational evidence indicates APOE2 benefits longevity independent of its protective effects on Alzheimer’s disease, which preserved activity and the metabolism of apoE protein and associated-lipids would be key to understanding.
2. 1. Neuroscience

   Divergent projections of the prelimbic cortex bidirectionally regulate active avoidance

   Maria M Diehl et al.

   Projections from the prelimbic prefrontal cortex targeting the ventral striatum or the basolateral amygdala bidirectionally regulate platform-mediated active avoidance in rats.
3. 1. Neuroscience

   Distinct subpopulations of mechanosensory chordotonal organ neurons elicit grooming of the fruit fly antennae

   Stefanie Hampel et al.
4. 1. Neuroscience

   Variation of connectivity across exemplar sensory and associative thalamocortical loops in the mouse

   Arghya Mukherjee et al.
5. 1. Neuroscience

   How many neurons are sufficient for perception of cortical activity?

   Henry William Peter Dalgleish et al.
6. 1. Neuroscience

   Neural encoding of task-dependent errors during adaptive learning

   Chang-Hao Kao et al.

   Posterior parietal cortex encodes errors in a task-dependent manner while a large array of frontal regions predict subsequent behavioral changes in response to ambiguous errors.
7. 1. Neuroscience

   Structural rearrangement of amyloid-β upon inhibitor binding suppresses formation of Alzheimer disease related oligomers

   Tobias Lieblein et al.
8. 1. Neuroscience

   Direct translation of climbing fiber burst-mediated sensory coding into post-synaptic Purkinje cell dendritic calcium

   Seung-Eon Roh et al.

   Purkinje cell dendritic calcium response is finely controlled by the burst activity of climbing fiber during sensory coding.
9. 1. Genetics and Genomics
   2. Neuroscience

   Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

   Marina Kovalenko et al.

   Genetic knockout of Hdac2 modifies molecular and cellular phenotypes in Huntington’s disease mice and has a prominent transcriptional regulatory role in adult medium spiny neurons.
10. 1. Computational and Systems Biology
    2. Neuroscience

    Training deep neural density estimators to identify mechanistic models of neural dynamics

    Pedro J Gonçalves et al.

    Deep neural networks can be trained to automatically find mechanistic models which quantitatively agree with experimental data, providing new opportunities for building and visualizing interpretable models of neural dynamics.