Neuroscience

Latest articles

1. 1. Neuroscience

   Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit

   Javier Díaz-Alonso et al.

   Despite being the key element of the classic model for excitatory synaptic plasticity, the cytoplasmic AMPA receptor C-tail is not required for hippocampal LTP.
2. 1. Neuroscience

   Recurrent processes support a cascade of hierarchical decisions

   Laura Gwilliams, Jean-Remi King

   The dynamics of neural responses during visual perception are best explained by a joint feedforward and recurrent architecture, which both maintains and broadcasts input features over time.
3. 1. Neuroscience

   Post-tetanic potentiation lowers the energy barrier for synaptic vesicle fusion independently of Synaptotagmin-1

   Vincent Huson et al.

   Modulation of the energy barrier for membrane fusion is a common mechanism by which sensors in the synapse produce supralinear calcium dependence of vesicle release and short-term synaptic potentiation.
4. 1. Neuroscience

   Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances learning of cue-reward contingency

   Richard B Crouse et al.
5. 1. Neuroscience

   External location of touch is constructed post-hoc based on limb choice

   Femke Maij et al.
6. 1. Neuroscience

   Ultra-high-field imaging reveals increased whole brain connectivity underpins cognitive strategies that attenuate pain

   Enrico Schulz et al.

   A single-trial whole-brain analysis of three cognitive strategies to attenuate pain shows that a more effective pain attenuation is associated with increased functional connectivity across the entire brain.
7. 1. Neuroscience
   2. Structural Biology and Molecular Biophysics

   Ca²⁺-dependent release of synaptotagmin-1 from the SNARE complex on phosphatidylinositol 4,5-bisphosphate-containing membranes

   Rashmi Voleti et al.

   Ca²⁺-free synaptotagmin-1 binds to neuronal SNARE complexes anchored on nanodiscs, and Ca²⁺ releases this interaction to induce tight, specific binding to PIP₂-containing membranes.
8. 1. Neuroscience

   A dual role for Ca_v1.4 Ca²⁺ channels in the molecular and structural organization of the rod photoreceptor synapse

   J Wesley Maddox et al.
9. 1. Neuroscience

   A whole-brain connectivity map of mouse insular cortex

   Daniel August Gehrlach et al.
10. 1. Cell Biology
    2. Neuroscience

    Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons

    Feline W Lindhout et al.

    A dynamic qualitative and quantitative map of human iPSC-derived neuronal stem cells transitioning into polarized neurons with the identification and characterization of a previously unrecognized axon developmental stage.