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Correction: Precise excitation-inhibition balance controls gain and timing in the hippocampus

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Cite this article as: eLife 2021;10:e71338 doi: 10.7554/eLife.71338

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Bhatia A, Moza S, Bhalla US. 2019. Precise excitation-inhibition balance controls gain and timing in the hippocampus. eLife 8:e43415. doi: 10.7554/eLife.43415.

Published 25, April 2019

#1 Figure 2 supplement figures 1 and 2 were swapped.

The error arose due to an oversight when we compiled the manuscript. The legends are consistent with the references in text, but the figure panels had been swapped.

#2 and #3: We inadvertently mentioned the concentrations of 3 chemicals from an older protocol that we had used. High sucrose artificial cerebro-spinal fluid (hsaCSF) did not contain glucose, NaH2PO4 in aCSF was 1.25mM and we used Na4-EGTA in the internal solution (not EGTA). All other chemicals and concentrations remain unchanged. The revised concentrations from the current protocol are underlined in the corrected text below.

#2 Methods (Slice preparation)

Original text:

Slices (350 microns) were cut in ice-cold high sucrose ASCF containing (in mM): 87 NaCl, 2.5 KCl, 1.25 NaH2PO4, 25 NaHCO3, 75 sucrose, 10 glucose, 0.5 CaCl2, 7 MgCl2. Slices were stored in a holding chamber, in artificial cerebro-spinal fluid (aCSF) containing (in mM) - 124 NaCl, 2.7 KCl, 2 CaCl2, 1.3 MgCl2, 0.4 NaH2PO4, 26 NaHCO3, and 10 glucose, saturated with 95% O2/5% CO2.

Corrected text:

Slices (350 microns) were cut in ice-cold high sucrose artificial cerebro-spinal fluid (hsaCSF) containing (in mM): 87 NaCl, 2.5 KCl, 1.25 NaH2PO4, 25 NaHCO3, 75 sucrose, 0.5 CaCl2, 7 MgCl2. Slices were stored in a holding chamber, in artificial cerebro-spinal fluid (aCSF) containing (in mM) - 124 NaCl, 2.7 KCl, 2 CaCl2, 1.3 MgCl2, 1.25 NaH2PO4, 26 NaHCO3, and 10 glucose, saturated with 95% O2/5% CO2.

#3 Methods (Electrophysiology)

Original text:

Pipettes were filled with internal solution containing (in mM): 130 K-gluconate, 5 NaCl, 10 HEPES, 1 EGTA, 2 MgCl2, 2 Mg-ATP, 0.5 Na-GTP and 10 Phosphocreatinine, pH adjusted to 7.3, osmolarity ~285 mOsm.

Corrected text:

Pipettes were filled with internal solution containing (in mM): 130 K-gluconate, 5 NaCl, 10 HEPES, 1 Na4-EGTA, 2 MgCl2, 2 Mg-ATP, 0.5 Na-GTP and 10 Phosphocreatinine, pH adjusted to 7.3, osmolarity ~285 mOsm.

#4

Additionally, owing to a production error the equal contributions for first and second author Aanchal Bhatia and Sahil Moza was erroneously omitted from the published version.

The article has been corrected accordingly.

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  1. Version of Record published: June 24, 2021 (version 1)

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© 2021, Bhatia et al.

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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