Response to comment on ‘SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung’
- Versiti Blood Research Institute, Department of Cell Biology Neurobiology and Anatomy Medical College of Wisconsin, United States
- Department of Pathology and Laboratory Medicine and UNC Blood Research Center, United States
- Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, United States
- Oak Ridge National Laboratory, Biosciences Division, United States
- University of Tennessee Knoxville, The Bredesen Center for Interdisciplinary Research and Graduate Education, United States
- Biomedical Informatics, Cincinnati Children’s Hospital Research Foundation, University of Cincinnati, United States
Figures
Figure 1
Correlation between log-fold change with rRNA and the adjusted log-fold change without rRNA (R2 ~0.99954).
Figure 2
Read mappings to the transcript NM_001993 for the F3 mRNA taken from one of the controls (top) and a case (bottom) used in Mast et al.
Mapping settings were set to mismatch cost = 2, insertion cost = 3, deletion cost = 3, length fraction = 0.95, similarity fraction = 0.95. The Alu element in the 3’UTR (brick), promoter (green), and coding sequence (dark yellow) of the transcript are annotated. Blue read mappings are paired reads that mapped a single time and light yellow are read mappings that aligned to multiple places in the transcriptome (i.e. other genes besides F3).
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Response to comment on ‘SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung’
eLife 11:e74951.
https://doi.org/10.7554/eLife.74951
