Replication Studies

Latest articles

1. 1. Cancer Biology

   Replication Study: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

   Hongyan Wang et al.

   Editors' Summary: This Replication Study did not reproduce those experiments in the original paper that it attempted to reproduce.
2. 1. Cancer Biology

   Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

   L Michelle Lewis et al.

   Editors' Summary: This Replication Study has reproduced important parts of the original paper, but it also contains results that are not consistent with some parts of the original paper.
3. 1. Cancer Biology

   Replication Study: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

   John Kerwin et al.

   Editors' Summary: This Replication Study has reproduced some parts of the original paper but it also contains results that are not consistent with other parts of the original paper.
4. 1. Cancer Biology

   Replication Study: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

   Mee Rie Sheen et al.

   Editors' Summary: This Replication Study has reproduced some parts of the original paper but other parts could not be interpreted.
5. 1. Cancer Biology

   Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

   Anthony Essex et al.

   Editors' Summary: This Replication Study has reproduced important parts of the original paper.
6. 1. Cancer Biology

   Replication Study: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

   Xuefei Yan et al.

   Editors' Summary: This Replication Study did not reproduce those experiments in the original paper that it attempted to reproduce.
7. 1. Cancer Biology

   Replication Study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

   Jeewon Kim et al.

   Editors' Summary: This Replication Study has reproduced some parts of the original paper but other parts could not be interpreted.
8. 1. Cancer Biology

   Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota

   Kathryn Eaton et al.

   Editors' Summary: This Replication Study has reproduced some parts of the original paper but it also contains results that are not consistent with other parts of the original paper.
9. 1. Cancer Biology

   Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

   John Repass, Reproducibility Project: Cancer Biology

   Editors' Summary: This Replication Study did not reproduce those experiments in the original paper that it attempted to reproduce.
10. 1. Cancer Biology

    Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells

    John P Vanden Heuvel et al.

    Editors' Summary: This Replication Study has reproduced some parts of the original paper but other parts could not be interpreted.