The amygdala (left and centre) and the ventral striatum (right) were activated at different stages during the game. Image credit: Johannes Schultz (CC BY 4.0)
Your relationships with the people around you – friends, family, colleagues – have a strong influence on your overall life happiness. Even so, many people struggle to engage with the people around them. Social interactions can be stressful and many people choose to avoid them, even at a cost.
Being able to measure these tendencies experimentally is a first useful step for assessing social avoidance without relying on people’s, often biased, recollections of their actions and behaviours. But how can a tendency to avoid social situations be quantified? And what can an experiment to measure this tendency reveal about the neural underpinnings of social avoidance?
Schultz et al. asked volunteers to play a social game. If they played, the volunteers had the chance to win three euros, but they could choose not to play and receive a fixed amount of money, which varied across trials between zero and three euros. This approach allowed Schultz et al. to quantify how much the volunteers valued playing the game. The game involved playing with other virtual human partners, who gave either positive or negative social feedback depending on the outcome of the game in the form of videos of facial expressions. In a non-social control experiment, a computer gave abstract feedback in the form of symbols.
Schultz et al. found that the value people placed on playing the social game varied with their level of social anxiety (established using a standard questionnaire). The more anxious people attributed less value to engaging in the game. Neuroimaging experiments revealed that the activity and connectivity between the amygdala and ventral striatum, two parts of the brain involved in processing emotions and reward-related stimuli, varied according to people’s levels of social anxiety.
Social interactions have a major impact on the quality of life of both healthy people and those with mental disorders. Developing new ways to measure and understand the differences in the brain linked to social traits could help to characterise certain conditions and document therapy progress. Methods to quantify social anxiety and avoidance are also in line with efforts to explore the neuroscience behind the full range of human behaviour.
