Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Big data analysis, protein structure prediction, and artificial intelligence are integrated to predict novel and highly transmissible SARS-CoV-2 variants.
Synaptic diversity in the ear's inner hair cells significantly empowers sound encoding to enable our processing of sounds across a broad range of intensities.
Lian Hollander-Cohen, Omer Cohen ... Berta Levavi-Sivan
Genetic loss-of-function approaches and functional calcium imaging reveal cholecystokinin as the primary regulator of follicle-stimulating hormone in zebrafish, redefining our understanding of gonadotropin regulation in vertebrates.
David Oestreicher, Shashank Chepurwar ... Tina Pangrsic
Analysis of Cabp1/2 double knockout phyenotype and rescue by viral delivery of Cabp2 identifies the interplay between two CaBPs to promote sustained synaptic transmission at the inner hair cell synapses.
Gasdermin D-mediated neutrophil pyroptosis plays an important role in driving inflammation in psoriasis, which unravels new pathogenesis of psoriasis and provides new insights into psoriasis treatment by targeting neutrophil pyroptosis.
The structural integrity of the right superior longitudinal fasciculus was identified as a neuroimaging predictor of chronic back pain, with potential for clinical translation.
Masahiro Takigawa, Marta Huelin Gorriz ... Daniel Bendor
A novel tool enables cross-checking the quality of replay events and evaluating the effectiveness of a given replay detection method in the absence of a ground truth.
Bethany M Bartlett, Yatendra Kumar ... Wendy A Bickmore
Evidence is provided suggesting that heterochromatin re-organisation during cell senescence can compromise the structural integrity of the nucleus, leading to activation of an inflammatory process.
