Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Marina Padilha, Victor Nahuel Keller ... Gilberto Kac
A panel of serum biomarkers, including dietary and microbial-derived metabolites related to the gut-brain axis, were identified as potential for tracking children at risk of early childhood developmental delays.
IL-6 signaling drives fibroblast activation in tendinopathy, emerging as a promising therapeutic target for these increasingly prevalent and costly tendon conditions.
The combination therapy of colistin, artesunate, and EDTA could serve as a promising approach to combat colistin-resistant Salmonella infections by disrupting bacterial membranes, collapsing proton motive force, and increasing reactive oxygen species levels.
FMT alleviated the intestinal barrier damage caused by enterotoxigenic Escherichia coli infection in antibiotic-induced microbiome-disordered model through increasing the relative abundance of A. muciniphila in the intestine.
Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.
Gut microbiota from young mice can alleviate gout and hyperuricemia in aged mice, further revealing that the metabolic product butyrate derived from the gut microbiota exerts similar therapeutic effects.
Cortical tracking of multi-scale temporal structures supports audiovisual integration of human motion via distinct modes, with superadditive integration at higher-order timescale linked to biological motion processing and autistic traits.
A novel method for factorizing complex cellular trajectories into interpretable bifurcation processes enhances the understanding of cell fate determination through the identification of key biological determinants in scRNA-seq data.
