Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Cognitive effort is aversive and people will accept physical pain to avoid it, but this avoidance does not appear to share the same fundamental characteristics of pain avoidance.
Exploiting virus-encoded ion channels as drug targets drove a multi-faceted approach to deriving potent small molecules targeting HCV p7, simultaneously providing new insights into its fundamental biology.
Phosphorylation-mediated inactivation of pro-apoptotic BCL-2 family protein BAD confers the apoptosis resistance on synovial sublining macrophages, thereby contributing to the development of rheumatoid arthritis.
A comparison of different bioimage analysis pipelines reveals how deep learning can be used for automatized and reliable analysis of fluorescent features in biological datasets.
The function and distribution of kinesin motors on exocytotic vesicles is dissected and visualized through a combination of gene knockout experiments, high-resolution microscopy and advanced data analysis.
Developmental regulatory mechanisms for peripheral nervous system formation appear to be conserved in ascidians despite extensive genomic divergence after 390 MY of separate evolution.
Dendritic cell recognition and processing of antigens from dead cells, utilising the Clec9A-damage recognition receptor, is controlled by a novel RNF41-ubiquitin-mediated regulatory pathway.
