Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Time-lapse analyses of millions of antibiotic-stressed Escherichia coli characterize the diverse single-cell dynamics of persister cells that depend on antibiotics, culture conditions, and pre-exposure history.
Gabriel O Heckerman, Eileen Tzng ... Adrienne Mueller
Based on a standardized screening process, the simple majority of reviewed cardiovascular research publications lack sufficient information needed for the study to be replicated or reproduced.
International Brain Laboratory, Kush Banga ... Yizi Zhang
An electrophysiology dataset generated by 10 laboratories from mice during perceptual decision-making reveals that reproducibility of systems neuroscience data requires stringent histological and electrophysiological quality-control criteria and careful analytical choices.
Epidermal mechanosensory responses contribute to acute detection of noxious mechanical stimuli and promote a form of prolonged mechanical hypersensitivity.
Rtf1 HMD is related to H2B ubiquitination and its downstream H3K4 methylation in both C. neoformans and C. deneoformans, thereby affecting its yeast-to-hypha transition and virulence.
Paleodemographic analyses in a hypothesis-testing framework show that the major life-history trait of seasonal migration has strong effects on long-term effective population sizes in a clade of songbirds.
A high-resolution atlas of the mouse dopaminergic system was obtained using single-nuclei RNA sequencing and spatial transcriptomics revealing molecular changes in a prodromal model of Parkinson's disease.
