Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.
FMT alleviated the intestinal barrier damage caused by enterotoxigenic Escherichia coli infection in antibiotic-induced microbiome-disordered model through increasing the relative abundance of A. muciniphila in the intestine.
Cortical tracking of multi-scale temporal structures supports audiovisual integration of human motion via distinct modes, with superadditive integration at higher-order timescale linked to biological motion processing and autistic traits.
A novel method for factorizing complex cellular trajectories into interpretable bifurcation processes enhances the understanding of cell fate determination through the identification of key biological determinants in scRNA-seq data.
Both genetic and pharmacological studies reveal an essential role for the CRF1 receptor in social behavior deficits induced by a single morphine administration in male, but not in female, mice.
Gut microbiota from young mice can alleviate gout and hyperuricemia in aged mice, further revealing that the metabolic product butyrate derived from the gut microbiota exerts similar therapeutic effects.
Nathan M Shugarts Devanapally, Aishwarya Sathya ... Antony M Jose
Transport of double-stranded RNA from parental circulation to progeny using the transmembrane protein SID-1 can occur through multiple routes during C. elegans development and buffer heritable changes in gene expression.
Jan H Kirchner, Lucas Euler ... Julijana Gjorgjieva
A mechanistic model based on the interaction of activity-independent cues from potential synaptic partners and local activity-dependent synaptic plasticity generates growing dendritic morphologies and non-random synaptic organization during development.