Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
A pioneering Bolivian seroepidemiological study employed innovative serological and neutralization assays as highly effective complements to genomic surveillance, delivering critical insights into SARS-CoV-2 variant circulation and informing public health strategies.
Charles-francois V Latchoumane, Joon-Hyuk Lee ... Hee-Sup Shin
The firing mode of mediodorsal thalamic neurons may act as a central switching mechanism for the level of arousal and consciousness in natural sleep and induced ethanol hypnosis in mice.
A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.
In vision-based flight control of hummingbird hawkmoths, the visual field partitions by natural cue prevalence into an optic flow and dorsal directional pathway, which integrate according to their relevance for flight safety.
Reproductive impairments in obese MC4R-deficient individuals are due to the absence of melanocortin signaling on Kiss1 neurons and not to their metabolic condition.
Genetic analyses of rare non-mosaic females define X-inactivation status for 380 genes and uncover widespread X-chromosome skewing in the general population, providing insights into sex-biased traits and X-linked disease expression.
Changes in the pericyte pool after stroke affect the restoration of the blood-brain barrier function and brain self-repair, and offer a new approach to therapy.
The architectures of human PIEZO1 and its slow-inactivating channelopathy mutants with or without its auxiliary subunit MDFIC reveal the inactivation mechanism of PIEZO channels.
