Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Karen Giménez-Orenga, Eva Martín-Martínez ... Elisa Oltra
Transcriptomic profiling of HERV elements at the loci level differentiates ME/CFS, fibromyalgia, and their overlap, revealing distinct immuno-epigenetic landscapes.
Shahriar Mowla, Linda Farahani ... Channa N Jayasena
There are common seminal microbiome clusters in both healthy men and those with infertility and recurrent pregnancy loss, and some specific microbiota perturbations are associated with impaired semen quality.
Analysis of monoclonal immunoglobulin A (IgA) antibodies after intranasal immunization highlights the crucial role of secretory IgA in mucosal immunity, enhancing our understanding of how intranasal vaccines can protect against SARS-CoV-2 infection.
Visual sequence exposure induces non-feature-specific elevated responses and time-compressed feature-specific backward replay, revealing twofold brain plasticity in the human brain.
J Daniel Obray, Erik T Wilkes ... L Judson Chandler
Adolescent alcohol exposure reduced basolateral amygdala-driven inhibition of pyramidal neurons projecting from the prefrontal cortex to the periaqueductal gray and increased inhibition of prefrontal parvalbumin interneurons.
Characterization of recurrent fusion proteins in rhabdomyosarcoma identified a Hippo pathway-independent mechanism involving VGLL2 and TEAD1 driving oncogenic transformation.
A cross-talk is revealed between two branches of metabolisms, amino acid limitation suppressing fatty acid biosynthesis, via posttranslational modifications of an enzyme involved in fatty acid biosynthesis.
MARK2-mediated phosphorylation of CAMSAP2 dynamically controls Golgi orientation by altering microtubule anchoring and polarity during directional cell migration.