Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Structural and biochemical analysis of human CtIP provides new insights into DNA break recognition, binding and bridging during homologous recombination.
A key transcription-factor for osteogenic differentiation, PLZF, acts as a transcriptional activator by binding to active developmental enhancers and facilitates mediator recruitment, but is not involved in enhancer looping.
Heterogeneity in perceptual sensitivity of human cone-mediated vision across wavelength originates in the cone photoreceptors, where S cones exhibit distinct functional properties in comparison to L and M cones.
Analysis of epigenetic recombinant inbred lines of Arabidopsis identified four hypomethylated DNA loci controlling quantitative disease resistance, which is associated with genome-wide priming of defence genes without affecting plant growth.
Cryo-EM structures of the gating cycle of bestrophin reveal the molecular underpinnings of activation and inactivation gating in this calcium-activated chloride channel and reveal a surprisingly wide pore.
