Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Genetic and biochemical analyses demonstrate that cell-surface lectin receptors can potentially function as extracellular NAD+-binding receptors and provide direct evidence for extracellular NAD+ being a bona fide endogenous signaling molecule in plants.
The foundations of genomic complexity in multicellular animals have deep roots in their unicellular prehistory, both in terms of innovations in gene content, as well as the evolutionary dynamics of genome architecture.
Striped expression of Dpp in Drosophila wing precursors leads to graded signalling activity that positions wing veins and, in parallel, promotes growth in a gradient-independent manner by supplying signalling activity above a threshold.
Dpp emanating from the anterior-posterior compartment boundary is continuously required to promote proliferative growth of the whole fly wing appendage.
A novel GABAAR assembly pathway that promotes synaptic inhibition is established and provides a molecular explanation for how GABAARs with distinct subunit compositions display distinct subcellular distributions.
The utility of split GFP for tissue-specific visualization of ribosomes in live Caenorhabditis elegans demonstrates the link between ribosomes and microtubules.
