Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
The blueprint and narrative of shape formation during early development can be objectively observed by quantifying and analyzing whole-embryo dynamics.
A longitudinal, deep learning approach reveals challenges and opportunities in establishing brain age as an effective metric of aging, with particular consideration given to underrepresented populations in Asia.
Haley N Mendoza-Romero, Jessica E Biddinger ... Richard Simerly
Hypothalamic microglia play an essential role in mediating changes to feeding circuitry caused by exposure to maternal HFD that may contribute to developmental programming of metabolic phenotype.
Jean Marc Tsagmo Ngoune, Parul Sharma ... Brice Rotureau
According to experimental and field observations, stumpy forms appear to be the most adapted forms for African trypanosome transmission from the mammalian host to the tsetse fly in natural conditions.
Advanced electron microscopy techniques have been applied to comprehensively describe the cellular details and ultrastructural characteristics of all sensilla within the external sensory system of Drosophila larvae.
A neurogenetic approach reveals the cellular division of labor between individual Drosophila larval dopaminergic neurons encoding an averive teaching signal, reflecting principles in the adult insect and vertebrate brain.
Individuals with a late circadian rhythm show the same deficits in motivational decision-making as those with neuropsychiatric symptoms, but only when tested in the morning.
Separating alpha oscillations from broadband activity reveals that alpha suppression in the human visual cortex is highly localized, and modulates cortical state in a manner consistent with exogenous spatial attention.
Functional neural circuit dissection identifies sensorimotor responses to noxious cold in Drosophila larvae revealing complex mechanisms by which nervous systems sense and respond to cold.