Research Articles

Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.

Latest articles

    1. Cell Biology

    ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals

    Natalya Pashkova et al.
    The family of ANTH domain proteins serve as adaptors to endocytose ubiquitinated proteins from the cell surface.
    1. Plant Biology

    Expression of a CO2-permeable aquaporin enhances mesophyll conductance in the C4 species Setaria viridis

    Maria Ermakova et al.
    The SiPIP2;7 aquaporin is a functional CO2 pore that can be used to improve CO2 diffusion at the interface between the airspace and leaf mesophyll which limits C4 photosynthesis.
    1. Neuroscience

    Control of neurotransmitter release by two distinct membrane-binding faces of the Munc13-1 C1C2B region

    Marcial Camacho et al.
    Two different binding modes of the Munc13-1 C­1C2B region govern synaptic vesicle priming and neurotransmitter release probability.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb

    Fang Huang et al.
    Cyclin T1 phosphorylation determines levels of P-TEFb via stabilizing interactions between cyclin T1 and CDK9.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Neurotoxin-mediated ­­potent activation of the axon degeneration regulator SARM1

    Andrea Loreto et al.
    1. Epidemiology and Global Health
    2. Medicine

    Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study

    Wuqing Huang et al.
    1. Structural Biology and Molecular Biophysics

    Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond

    Márton A Simon, László Csanády
    1. Cell Biology

    Src activates retrograde membrane traffic through phosphorylation of GBF1

    Joanne Chia et al.
    1. Microbiology and Infectious Disease

    The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell

    Jennifer E Dumaine et al.
    1. Developmental Biology

    Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach

    Ali Seleit et al.
Load more