Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
ATP6V0A1 was identified as a key player in nephropathic cystinosis-related renal pathology, with antioxidants like ATX emerging as potential treatments to restore V0A1 expression, mitochondrial function, and balance autophagic processes.
Genetic diversity is strongly associated with ecosystem functions across natural trophic chains, showing that it can be as important as species diversity.
Gülnihal Kavaklioglu, Alexandra Podhornik ... Christian Seiser
DNA hypomethylation in human tumor cells results in the activation of the LINE-1-derived RNA-binding protein L1TD1 and its interactions with LINE-1 transposons.
V2 exhibits interdigitated columnar organizations for color and disparity that involved feedforward and feedback processing, while the texture selectivity is primarily driven by feedback modulations from V4.
Multimodal imaging reveals overlapping gradients of hippocampal connectivity reflecting patterns of cortical function, dopamine receptor distribution, and individual differences in memory, with age-related dedifferentiation of gradient organization marking cognitive decline.
Torsten Günther, Jacob Chisausky ... Cristina Valdiosera
After their introduction to the Iberian peninsula, domestic cattle hybridised with mostly male wild aurochs for millennia until human actions likely ended this process about 4000 years ago.
Pooja Popli, Arin K Oestreich ... Ramakrishna Kommagani
Autophagy sustains oviduct homeostasis, modulates inflammation, and prevents excessive pyroptosis, ensuring efficient embryo transport and a well-balanced reproductive tract environment.
