Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
The H+ influx coupled to nutrient uptake and the plasma membrane H+-ATPase are central actors of the activation of target of rapamycin complex 1 (TORC1) in budding yeast Saccharomyces cerevisiae..
Autosomal dominant IRF4 deficiency is the first genetic etiology of Whipple's disease, a very rare chronic condition following a rather common infection by
Tropheryma whipplei.
Acute intermittent hypoxia is a noninvasive approach that enhances corticospinal function in humans, likely through alterations in corticospinal-motoneuronal synaptic transmission.
Developmental genetic and cell culture studies indicate that the Inhibitor of DNA-binding protein Extra macrochaetae (Emc), previously thought to determine where bHLH proteins can act, is itself regulated by those bHLH dimerization partners at the level of protein stability.
Computational and theoretical analyses offer novel and unexpected insight into how complex, naturally occurring odor mixtures are parsed and normalized at the very first stage of olfaction.
A pain-relaying ion channel on a hypersensitive population of sensory neurons can instead elicit sensations of itch in both fish and mice when directly activated, providing a novel model of itch transduction.
A riboswitch class has been discovered for phosphoribosyl pyrophosphate, the biochemical precursor of nucleotides, and this novel RNA sensor commonly operates in tandem with a guanine aptamer to function like a Boolean logic gate.
