Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Higher biosynthetic capacity of gut microbes in individuals diagnosed with noncommunicable diseases or taking antibiotics suggests that diversity loss and 'dysbiosis' result from microbiome restructuring in response to ecosystem disruption.
Katarzyna Tutak, Izabela Broniarek ... Krzysztof Sobczak
Identification of ribosomal proteins RPS26 and RPS25, along with chaperone TSR2, as new important modifiers in the noncanonical translation process linked to fragile X premutation disorders.
Rare individuals treated for congenital cataracts demonstrated shifts in the visual cortex’s excitatory/inhibitory balance even decades post-surgery, reflected by alterations in the neurotransmitter concentration ratio and aperiodic electroencephalogram activity.
Lili Karashchuk, Jing Shuang Li ... Bingni W Brunton
A model that simulates realistic fly walking uses an anatomically-inspired layered architecture to achieve robust walking, quantifying the tolerance of this circuit to sensorimotor delays.
AARS2 safeguards cardiomyocytes against ischemic injury by modulating PKM2-driven energy metabolism, revealing the AARS2-PKM2 axis as a previously unrecognized cardioprotective pathway in myocardial infarction.
Dendritic cell (DC)-derived IL-27 establishes CD4+ T cell bias against IFN-γ via STAT1 and epigenetics, linking thymic development to autoimmune mechanisms.
Matthew Rosenblatt, Saloni Mehta ... Dustin Scheinost
Self-citation rates differed by geographic region, seniority, gender, and field, which may ultimately affect the perceived influence of authors in these subgroups in neuroscience literature.