Image showing the inner ear of a Mongolian gerbil hearing a loud sound. Colors indicate the level of vibrations caused by the sound in the region where the ear’s hair cells are located. Image credit: Vavakou et al. (CC BY 4.0)
Our ears give us our sense of hearing. Their job is to collect sounds and pass this information on to the brain. Hair cells, a special group of cells in the ear, are responsible for detecting sound vibrations and turning them into the electrical signals that our brains can understand.
The ear contains two populations of hair cells: inner hair cells that send signals to the brain, and outer hair cells that act as a protective ‘buffer’ by modulating sound vibrations entering the innermost part of the ear. When outer hair cells are damaged, the vibrations picked up by inner hair cells are much smaller than in a healthy ear. This has led to the idea that outer hair cells actively amplify sounds before passing them on. That is, outer hair cells simultaneously act like microphones (by receiving sound from the environment) and loudspeakers (by re-emitting magnified vibrations).
One problem with this amplifier theory is that it cannot explain how some animals are able to hear extremely high-pitched sounds. If the theory is true, outer hair cells should be able to re-emit ultrasonic vibrations. However, some observations suggest that they may not vibrate fast enough to do so.
To test the amplifier theory, Vavakou et al. measured how outer hair cells in the ear of Mongolian gerbils responded to different sounds. This revealed that the motion of these cells could keep up with moderately high sounds (around the upper end of a piano’s range), but were too sluggish to amplify ultrasound despite gerbils having good ultrasonic hearing. Further experiments showed that instead of acting like amplifiers, outer hair cells seem to monitor the loudness of sound and adjust the level accordingly before passing the vibrations on to the inner hair cells.
These results shed new light on how outer hair cells help our ears work. Since damage to these cells can cause hearing loss, understanding how they work could one day guide new methods of protecting or even restoring hearing in vulnerable patients.
