Short Reports

A Short Report allows authors to publish the results of a small number of experiments, provided the conclusion is clear and justified, and the findings are novel and judged to be of high importance.

Latest articles

    1. Cell Biology
    2. Immunology and Inflammation

    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death

    Jazlyn P Borges, Ragnhild SR Sætra ... Benjamin Ethan Steinberg
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies

    Mingyao Pan, Bo Li
    Amino acid codon degeneracy indicates antigen-specific selection of the T cell receptors and is predictive of cancer immunotherapy outcomes.
    Short Report Updated
    Formats available:
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    1. Structural Biology and Molecular Biophysics

    Structural and functional insights of the human peroxisomal ABC transporter ALDP

    Yutian Jia, Yanming Zhang ... Guanghui Yang
    The Cryo-EM structural and biochemical analysis provides a framework for understanding the working mechanism of ALDP.
    Short Report Updated
    Formats available:
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    1. Neuroscience

    Visual experience has opposing influences on the quality of stimulus representation in adult primary visual cortex

    Brian B Jeon, Thomas Fuchs ... Sandra J Kuhlman
    Stimulus representation in primary visual cortex rebounds to its original state following therapeutic sensory deprivation in adults.
    1. Neuroscience

    Higher-order unimodal olfactory sensory preconditioning in Drosophila

    Juan Martinez-Cervantes, Prachi Shah ... Isaac Cervantes-Sandoval
    Drosophila flies infer value to olfactory stimuli based on the previously repeatedly presented associative structure between two odorants.
    Short Report Updated
    Formats available:
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    1. Cell Biology
    2. Genetics and Genomics

    Resurrecting essential amino acid biosynthesis in mammalian cells

    Julie Trolle, Ross M McBee ... Harris H Wang
    Mammalian cells were engineered to synthesize valine, a metabolic capacity that had been lost from the lineage of higher eukaryotes for >500 million years.
    Short Report Updated
    Formats available:
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    1. Neuroscience

    Machine learning-assisted fluoroscopy of bladder function in awake mice

    Helene De Bruyn, Nikky Corthout ... Thomas Voets
    A new combined approach using X-ray fluoroscopy and machine learning provides detailed new insights into bladder function in awake, unrestrained mice and unveils important limitations of current approaches to study bladder function.
    Short Report Updated
    Formats available:
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    1. Developmental Biology

    RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification

    Erica J Hutchins, Shashank Gandhi ... Marianne E Bronner
    The RNA-binding protein Elavl1 directly binds to and stabilizes a single gene product—Draxin mRNA—to prevent premature delamination and maintain specification in cranial neural crest.
    1. Neuroscience

    Mixed synapses reconcile violations of the size principle in zebrafish spinal cord

    Evdokia Menelaou, Sandeep Kishore, David L McLean
    In the zebrafish spinal cord, mixed synapses contribute to neuronal connectivity and resting excitability, which helps explain violations of the well-known 'size principle' of recruitment.