Short Reports

A Short Report allows authors to publish the results of a small number of experiments, provided the conclusion is clear and justified, and the findings are novel and judged to be of high importance.

Latest articles

    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability

    Kanishk Jain, Matthew R Marunde ... Brian D Strahl
    MLL1-mediated H3K4 methylation is directly enhanced by cis-tail H3 acetylation, as shown through both in vitro and in vivo experiments.
    Short Report Updated
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    1. Neuroscience

    Self-organization of songbird neural sequences during social isolation

    Emily L Mackevicius, Shijie Gu ... Michale S Fee
    In juvenile songbirds, neural sequences pre-exist tutor exposure, and the process of learning a new song may make use of existing neural sequences as a stable substrate for new behavioral changes.
    1. Neuroscience

    Theta- and gamma-band oscillatory uncoupling in the macaque hippocampus

    Saman Abbaspoor, Ahmed T Hussin, Kari L Hoffman
    Oscillations that co-occur in hippocampal CA1 during exploration in the rodent are shown to segregate according to exploratory and sleep states in the primate.
    Short Report Updated
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell transcriptomics of a dynamic cell behavior in murine airways

    Sheldon JJ Kwok, Daniel T Montoro ... Vladimir Vinarsky
    Live imaging of cells in an intact murine tissue combined with single-cell sequencing reveals a unique transcriptional signature of an observed cellular behavior.
    Short Report Updated
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    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure of the endothelin-1-ETB-Gi complex

    Fumiya K Sano, Hiroaki Akasaka ... Osamu Nureki
    The cryo-EM structure of ETB-Gi complex, obtained using the Fusion-G system, provides insights into the distinct activation mechanism and G-protein promiscuity of ETB, aiding in the design of ETB agonists for therapeutic applications.
    1. Biochemistry and Chemical Biology

    Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors

    Lisa Goebel, Tonia Kirschner ... Daniel Rauh
    The important oncogene KRasG13C can be targeted by covalently binding nucleotide-analogues, resulting in a locked protein that can no longer induce oncogenic signaling.
    1. Neuroscience

    Genetic dissection of mutual interference between two consecutive learning tasks in Drosophila

    Jianjian Zhao, Xuchen Zhang ... Qian Li
    Proactive interference is regulated by the CSW/Raf/MAPK pathway, while retroactive interference is regulated by the Rac1 pathway.
    Short Report Updated
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    1. Genetics and Genomics

    Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations

    Chiara Auwerx, Marie C Sadler ... Eleonora Porcu
    Integrating multi-omics quantitative trait loci and genome-wide association study data into a multivariable Mendelian randomization framework allows to identify metabolite-mediated transcript-to-phenotype causal relations missed by methods focusing on a single omics layer.
    1. Cancer Biology
    2. Medicine

    Long COVID in cancer patients: preponderance of symptoms in majority of patients over long time period

    Hiba Dagher, Anne-Marie Chaftari ... Issam I Raad
    Long COVID occurred in the majority of cancer patients diagnosed with acute COVID-19 with a preponderance of symptoms (such as fatigue, sleep disturbances, and gastrointestinal symptoms) over a long time period.
    Short Report Updated
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    1. Genetics and Genomics

    Recognition of galactose by a scaffold protein recruits a transcriptional activator for the GAL regulon induction in Candida albicans

    Xun Sun, Jing Yu ... Yang Lu
    The transcriptional network for the GAL regulon induction in the pathogenic fungus Candida albicans represents an important advance in the evolution of the regulatory circuits, and would make a nice addition to the textbook version of eukaryotic gene regulation.
    Short Report Updated
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