A Short Report allows authors to publish the results of a small number of experiments, provided the conclusion is clear and justified, and the findings are novel and judged to be of high importance.
Marie-Eve Picard, Miriam Kunz ... Pierre Rainville
Facial expression provides a complementary channel to communicate pain experiences and reflects the activation of brain mechanisms partly distinct from those associated with subjective self-reports of pain.
Two alternative models of PKA activation were tested in neurons, and the results support the classical model in which the catalytic subunit dissociated from the regulatory subunit upon activation.
SLC35G1 is the first highly chloride-sensitive transporter localized on the basolateral membrane of intestinal epithelial cells, responsible for citrate absorption.
Sachin P Gadani, Saumitra Singh ... Pavan Bhargava
Leptomeningeal inflammation in a mouse model of multiple sclerosis triggers deeply penetrating gene changes in underlying brain tissue, described using spatial transcriptomics.
Design and characterization of allosteric mutations that recapitulate TRPML1 gating and structural insights into PI(4,5)P2 and sphingomyelin inhibition of TRPML1.
Novel genetic fate-mapping strategies enabled re-analysis of cortical oligodendrocytes derived from dorsal pallium, LGE/CGE, and MGE/POA, challenging the canonical view of substantial LGE/CGE contributions and the elimination of MGE/POA-derived populations.
There is a systemic bias in research evaluation, i.e., disciplines with a higher proportion of women have lower evaluations and funding success for all researchers, regardless of gender.
