Short Reports

A Short Report allows authors to publish the results of a small number of experiments, provided the conclusion is clear and justified, and the findings are novel and judged to be of high importance.

Latest articles

    1. Microbiology and Infectious Disease

    The intricate relationship of G-Quadruplexes and bacterial pathogenicity islands

    Bo Lyu, Qisheng Song
    Unveiling the intricate web of interactions between G4 structures and pathogenicity islands in 89 bacterial genomes significantly advances our understanding of bacterial virulence mechanisms.
    1. Genetics and Genomics

    Auxin exposure disrupts feeding behavior and fatty acid metabolism in adult Drosophila

    Sophie A Fleck, Puja Biswas ... Lesley N Weaver
    Adult Drosophila exposed to auxin at the recommended concentrations for the AGES transgene expression system display defects in feeding behavior, have altered metabolic transcripts, and have reduced triacylglyceride levels.
    1. Biochemistry and Chemical Biology
    2. Stem Cells and Regenerative Medicine

    BRAIDing receptors for cell-specific targeting

    Hui Chen, Sung-Jin Lee ... Yang Li
    A novel strategy to activate the WNT pathway in a cell type selective manner by linking designer ligands with target cell specific bridging receptors.
    1. Chromosomes and Gene Expression

    Adenine methylation is very scarce in the Drosophila genome and not erased by the ten-eleven translocation dioxygenase

    Manon Boulet, Guerric Gilbert ... Lucas Waltzer
    Biochemical, molecular, and genetic analyses show that in Drosophila the epigenetic enzyme TET does not demethylate 6mA, which is scarce in the genome, but rather acts in a catalytic-independent manner.
    1. Physics of Living Systems

    An in silico testbed for fast and accurate MR labeling of orthopedic implants

    Gregory M Noetscher, Peter J Serano ... Sergey N Makaroff
    Radio frequency heating induced during magnetic resonance procedures within patients that carry embedded passive orthopedic implants may be accurately estimated through modeling and simulation.
    1. Neuroscience

    Flexible coding of time or distance in hippocampal cells

    Shai Abramson, Benjamin J Kraus ... Genela Morris
    The hippocampus demonstrates flexible coding during memory encoding, prioritizing either distance or time information based on the specific requirements of the experiment.
    Short Report Updated
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    1. Cell Biology

    Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes

    Xiang Wang, Vitaliy V Bondar ... Anastasia G Henry
    Rab12 was identified as a key modulator of LRRK2-dependent Rab phosphorylation that mediates the recruitment of LRRK2 to lysosomes in response to damage.
    Short Report Updated
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    1. Cell Biology

    Multiple cullin-associated E3 ligases regulate cyclin D1 protein stability

    Ke Lu, Ming Zhang ... Di Chen
    Cyclin D1 protein stability is regulated by ubiquitin-proteasome mechanism mediated by multiple E3 ligases, including newly identified Keap1, DDB2, and WSB2.
    Short Report Updated
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    1. Neuroscience

    Conscious processing of global and local auditory irregularities causes differentiated heartbeat-evoked responses

    Diego Candia-Rivera, Federico Raimondo ... Jacobo D Sitt
    Brain-heart interactions under the processing of auditory irregularities could help to distinguish whether a patient is in a vegetative state or in a minimally conscious state.
    Short Report Updated
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    1. Cancer Biology
    2. Medicine

    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma

    He Liu, Meisuo Liu ... Yongliang Yang
    Deep reinforcement model and experimental evaluations identified a small-molecule CRM1 inhibitor that can selectively ablate extranodal NK/T cell lymphoma cells.
    Short Report Updated
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