Shifting perception

A cube that seems to shift its spatial arrangement as you keep looking; the elegant silhouette of a pirouetting dancer, which starts to spin in the opposite direction the more you stare at it; an illustration that shows two profiles – or is it a vase? These optical illusions are examples of bistable visual perception. Beyond their entertaining aspect, they provide a way for scientists to explore the dynamics of human consciousness, and the neural regions involved in this process.

Some studies show that bistable visual perception is associated with the activation of the prefrontal cortex, a brain area involved in complex cognitive processes. However, it is unclear whether this region is required for the illusions to emerge. Some research has showed that even if sections of the prefrontal cortex are temporally deactivated, participants can still experience the illusions.

Instead, Takamitsu Watanabe proposes that bistable visual perception is a process tied to dynamic brain states – that is, that distinct regions of the prefontal cortex are required for this fluctuating visual awareness, depending on the state of the whole brain. Such causal link cannot be observed if brain activity is not tracked closely.

To investigate this, the brain states of 65 participants were recorded as individuals were experiencing the optical illusions; the activity of their various brain regions could therefore be mapped, and then areas of the prefrontal cortex could precisely be inhibited at the right time using transcranial magnetic stimulation. This revealed that, indeed, prefrontal cortex regions were necessary for bistable visual perception, but not in a simple way. Instead, which ones were required and when depended on activity dynamics taking place in the whole brain. Overall, these results indicate that monitoring brain states is necessary to better understand – and ultimately, control – the neural pathways underlying perception and behaviour.