Katrin Franke, Chenchen Cai ... Andreas Savas Tolias
Widespread color-opponency in mouse V1 enhances object decoding in the sky, highlighting the evolutionary importance of color processing in non-primate species.
Signals from primate rod photoreceptors do not exhibit the light-level-dependent routing through parallel retinal circuits observed in rodents and often invoked in interpreting psychophysical experiments.
Heterogeneity in perceptual sensitivity of human cone-mediated vision across wavelength originates in the cone photoreceptors, where S cones exhibit distinct functional properties in comparison to L and M cones.
A combination of physiological and perceptual experiments show that the responses of rod photoreceptors inhibit those of cones more than vice versa, and reveal both the site of the retinal interaction and the underlying mechanism.
Loïs S Miraucourt, Jennifer Tsui ... Edward S Ruthazer
Endocannabinoid activation of the CB1 receptor on retinal ganglion cells in the eye results in enhanced excitability and responsiveness to visual stimulation through a novel mechanism involving intracellular chloride regulation.
Retinal visual response properties in awake mice are similar to those under anesthesia or ex vivo, but not exactly the same, so knowledge of retinal function cannot be simply translated from ex vivo to in vivo.