Figures and data
Experimental design.
(A) Measures taken in the BRIGHT project used in this work. The measuring tape represents anthropometric measures, the brain represents fNIRS FC and the test represents the cognitive flexibility assessment. (B) Schematic representation of the spatial layout of the fNIRS array. Sources are marked with red stars, detectors are marked with blue circles, channels are marked with grey lines and numbered with black circles. The channels/optodes used as a reference for the tragus are highlighted in green.
Linear mixed models results showing FC that displayed a statistically significant change with age.
(A) Significant results of the linear mixed model, blue indicates connections that decreased with age, red indicates connections that increase with age. (B) Mean and standard error of the mean (SE) of the functional connections that changed with age (HbO2). Error bars are 1 SE. (C) Violin plot showing the mean ± standard deviation (SD) (red circles and lines) and the individual variability (coloured dots) of the FC that showed a change with time (HbO2).
FC that significantly changed with age.
Results are displayed in terms of estimated betas, standard errors and p values that survived Bonferroni correction. Regressions that survived Bonferroni correction for multiple comparisons are in bold.
Results of the regression analyses of the effect of ΔWLZ on FC at 24 months.
Significant positive associations are in green, significant negative associations are in orange, and non-significant (NS) associations are in blue; * indicates regressions that are still significant after correcting for HCAZ at 7/14 days and ** indicates regressions that are still significant after correcting for neonatal HCAZ and WLZ. Regressions that survived FDR correction for multiple comparisons are in bold.
Associations between FC, early growth and later cognitive flexibility.
(A) Significant positive associations are in green, significant negative associations are in orange, and non-significant associations are in blue. * indicates regressions that survived FDR correction for multiple comparisons. (B) Schematic representations of the early FC connections shown to predict cognitive flexibility in preschoolers. Significant positive associations are in green, significant negative associations are in orange (these results did not survive corrections for multiple comparisons).
