Improvement in regularity of meals, body weight changes, and correlation between loss of body weight and regularity of eating meals. (A, B) Times of day of calorie intake occasions of 15 representative participants of the EG (A) and the CG (B) during the two-week exploration phase (left) and the six-week intervention phase (right). Each point represents a calorie intake occasion. (C, D) Change in MTVS of participants in the CG (gray) and EG (cyan) of breakfast, lunch, and dinner (C) and of all meals combined (D), including snacks, if snacks were taken. 2-way repeated-measures ANOVA with Bonferroni post hoc test comparing CG and EG during the exploration or intervention phase and T0-T1 and T1-T2 within groups, * p ≤ 0.05, ** p ≤ 0.01, **** p ≤ 0.0001. CG: n=33; EG: n=64-67, missing n-values in the EG are due to the different number of meals for each participant. Detailed statistics in Tables S3. (E) Within group differences of body weight during the study. Body weight was collected at different time points, at the beginning of the study (T0), after the exploration phase (T1), after the intervention phase (T2), and after the follow-up phase (T3). During the follow-up phase, 34 EG participants voluntarily continued the intervention (continuing; black line and open circle) while 33 participants no longer followed the intervention (discontinuing; gray, dashed line and open circle). Only three control subjects continued their intervention in the follow-up phase, which is why a division into continuing and discontinuing was omitted in this group. Data are normalized so that all baseline data at T0 equals 0 to represent change. Differences of all CG and EG participants between T0, T1, and T2 were calculated with a 1-way ANOVA, as were differences between T2 and T3 of CG participants (Bonferroni post-hoc test, **** p ≤ 0.0001). Differences between T2 and T3 of continuing and discontinuing EG participants were calculated with a paired t-test °° p ≤ 0.01, °°°° p ≤ 0.0001. Detailed statistics in Table S4. (F) Between group differences of BMI from T0-T3. Mixed-effect model with Bonferroni post-hoc test comparing CG and EG at different phases during the study, **** p ≤ 0.0001. Detailed statistics in Table S5. (G) Significant correlation between body weight/BMI and MTVS. The more participants improved their regularity of meals (decreasing MTVS), the more weight/BMI they lost. Linear regression, CG: n=33; EG: n=67, ** p ≤ 0.01. Detailed statistics in Tab. S6. (H) Significant correlation between body weight/BMI and MTVS of lunch and dinner. The more participants improved their regularity of lunch and dinner (decreasing MTVS), the more weight/BMI they lost. Linear regression, CG: n=33; EG: n=67, ** p ≤ 0.01. Detailed statistics in Tab. S6. (I) Significant correlation between change in BMI, baseline BMI, and improvement in MTVS. Individuals with higher BMI benefit more from similar improvements in MTVS (shades of data points) than individuals with lower BMI in EG participants. Multiple regression, n=67, * p ≤ 0.05, ** p ≤ 0.01. Detailed statistics in Tab. S8.