335 results found
    1. Neuroscience

    Sensory experience inversely regulates feedforward and feedback excitation-inhibition ratio in rodent visual cortex

    Nathaniel J Miska, Leonidas MA Richter ... Gina G Turrigiano
    Sensory deprivation suppresses cortical responsiveness through a selective remodeling of excitatory and inhibitory microcircuit motifs, by simultaneously amplifying feedforward and suppressing feedback excitation.
    1. Neuroscience

    Flexible motor sequence generation during stereotyped escape responses

    Yuan Wang, Xiaoqian Zhang ... Quan Wen
    Time-ordered and flexible motor sequences in C.elegans are generated by combining an excitatory feedforward coupling and mutual inhibitions between neurons in different functional modules.
    1. Neuroscience

    Fast and slow feedforward inhibitory circuits for cortical odor processing

    Norimitsu Suzuki, Malinda LS Tantirigama ... John M Bekkers
    In vivo whole-cell recordings in the piriform cortex show that two classes of layer 1 interneurons respond differently to odors, suggesting that these neurons provide kinetically distinctive types of odor-evoked feedforward inhibition.
    1. Neuroscience

    Precise excitation-inhibition balance controls gain and timing in the hippocampus

    Aanchal Bhatia, Sahil Moza, Upinder Singh Bhalla
    Delayed inhibition precisely balances excitation from arbitrary combinations of CA3 neurons and controls the gain of CA1 output by reducing inhibitory delay with increasing excitation.
    1. Neuroscience

    Recruitment of inhibition and excitation across mouse visual cortex depends on the hierarchy of interconnecting areas

    Rinaldo David D'Souza, Andrew Max Meier ... Andreas Burkhalter
    The relative recruitment of excitatory and inhibitory neurons by cortico-cortical interareal pathways depends on the hierarchy of areas and the laminar location of the neurons.
    1. Neuroscience

    Differential inhibition onto developing and mature granule cells generates high-frequency filters with variable gain

    María Belén Pardi, Mora Belén Ogando ... Antonia Marin-Burgin
    Immature and mature granule cells in the hippocampal dentate gyrus show differing responses to physiologically relevant stimuli, with immature cells better at encoding stimulus frequency and mature cells better at encoding stimulus onset.
    1. Neuroscience

    A tonic nicotinic brake controls spike timing in striatal spiny projection neurons

    Lior Matityahu, Jeffrey M Malgady ... Joshua L Plotkin
    A novel mechanism describes how tonic activation of nicotinic acetylcholine receptors can modulate the timing of striatal output by priming feedforward inhibition.
    1. Neuroscience

    Frequency-selective control of cortical and subcortical networks by central thalamus

    Jia Liu, Hyun Joo Lee ... Jin Hyung Lee
    Central thalamus relay neurons dynamically switch the activity of cortical and subcortical networks at distinct frequencies, providing a mechanism for this region's role in arousal regulation.
    1. Neuroscience

    Connectomics of the Octopus vulgaris vertical lobe provides insight into conserved and novel principles of a memory acquisition network

    Flavie Bidel, Yaron Meirovitch ... Binyamin Hochner
    Connectomics of the octopus 'fan-out fan-in’ learning network reveals that the intermediate layer uses approximately 22×106 excitatory interneurons, each can store a single sensory input, while approximately 400×103 integrating inhibitory interneurons adjust the network output level.
    1. Neuroscience

    Inhibition stabilization is a widespread property of cortical networks

    Alessandro Sanzeni, Bradley Akitake ... Mark H Histed
    The strongly coupled theoretical regime describes the function of mouse sensory and motor cortical areas.

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