‘Hexagonal’ panels (panels 1, 4, 6, 8), network of sequentially activated neurons (cell assemblies) during sleep/rest under different experimental conditions: pre-DnRun1 sleep/rest (panel 1), post-DnRun1 sleep/rest (panel 4), pre-ContigRun sleep/rest (panel 6), and post-ContigRun sleep/rest (panel 8). Arrows indicate potential (thin) or actual (bold) temporal order of activation during Run in CA1, not anatomical connectivity. All arrows during sleep/rest indicate the temporal order of cell activation during sleep/rest. Black bold arrows during sleep/rest emphasize temporal replay. Upper case letters: corresponding individual cells/assemblies. Colors: sequential cell assemblies co-active on a given linear track. Cells A, C, and D are active on both the familiar and novel arms. White circles: cells with no place field during the corresponding run session. ‘Linear’ panels (panels 2, 3, 5, 7), sequences of place cells during different sessions of run on linear tracks: DnRun1 (early, panel 2 and late, panel 3, of the run session), DnRun2 (panel 5), and ContigRun (panel 7). Letters, colors, and order of activation correspond to the ones during sleep/rest sessions. Long thin arrows next to the panel represent the direction of the animal’s movement during run.