1. Neuroscience

Regulation of food intake by mechanosensory ion channels in enteric neurons

  1. William H Olds
  2. Tian Xu  Is a corresponding author
  1. Howard Hughes Medical Institute, Boyer Center for Molecular Medicine, Yale University School of Medicine, United States
  2. Fudan-Yale Center for Biomedical Research, Fudan University, China
https://doi.org/10.7554/eLife.04402
Share this article
Cite this article
  1. William H Olds
  2. Tian Xu
(2014)
Regulation of food intake by mechanosensory ion channels in enteric neurons
eLife 3:e04402.
https://doi.org/10.7554/eLife.04402
  2. Download BibTeX
  3. Download .RIS
2 figures

Figures

Figure 1
Download asset Open asset
Modulating activities of Drosophila PENs causes metabolic defects.

(A) Enteric neural projections of Gal4 lines tested (red, phalloidin; green, UAS-mCD8::GFP) and their diagram (B). GMR51F12-Gal4 neurons project to the foregut, anterior midgut and crop. GMR48A05-Gal…

https://doi.org/10.7554/eLife.04402.003
Figure 2
Download asset Open asset
PPK1 functions in Drosophila PENs to regulate feeding.

(A–B) Results of capillary feeding assays by either inactivating (A, Ilp7-Gal4 or HGN1-Gal4; UAS-shiTS1) or activating (B, Ilp7-Gal4 or HGN1-Gal4; UAS-TRPA1) the PENs (n = 4–8 replicates). (C) …

https://doi.org/10.7554/eLife.04402.004

Download links