(A) An example of two ganglion cells responding to a bar flashed on their receptive field centres for 100 ms (−100% contrast). (B) The response of the same cells to a bar of width 160 µm (2.4º) moving at 500 µm s−1 (7.5º s−1). The position of the bar relative to a cell's receptive field is shown above for the different time points indicated by the lettered arrows. (C) A comparison of the delay for the maximal response to a flashed stimulus (62 ± 2.6 ms) and the time of maximal spiking to a moving stimulus relative to the time at which the stimulus reached the centre of the RF (−46 ± 12.6 ms; n = 25 ganglion cells; p < 0.0001). BT = Brisk-transient, BS = Brisk Sustained, OS = Orientation-selective, see ‘Materials and methods’ for cell classification. (D) The degree of motion anticipation was correlated with the RF size (Pearson's r = −0.593, n = 25). (E) Schematic of retinal feedback circuits in the inner plexiform layer (IPL), excitation and inhibition are represented by green and red arrows respectively. (F) Schematic of feed-forward inhibition in the IPL. (G) The dynamics of the EPSC evoked by a −100% contrast bar flashed over the RGCs RF centre for 320 ms. Individual cells were normalised before averaging (n = 12, SEM in grey). (H) Example of the EPSC recorded as a bar moves across the receptive field of an OFF ganglion cell (average of six presentations). The peak EPSC lags behind the receptive field centre by 79 ± 17 μm (1.2 ± 0.3º, n = 7). The purple line indicates the expected linear response obtained from convolution of the receptive field with the EPSC in F. The motion evoked EPSC was not significantly different from the expected linear response, indicating that lateral inhibition is not present (using the Kolmogorov–Smirnov test, n = 7). (I) Orientation selective cells did show a clear indication of lateral inhibition (n = 2).