Effects of 300 mg/kg SS on peripheral and central electrophysiological measures. (A) Mean (+SEM, n = 5) compound action potential (CAP) input/output function (average of 6, 8, 12, 16, 20, 24, 30, and 40 kHz; 10-ms tone burst) recorded from the round window pre- and 2 hr post-SS. Note, 20 dB threshold shift of the function to the right at low intensities (horizontal arrow) and large reduction in CAP amplitude at high intensities (down arrow). (B, C, D) Local field potential input/output functions (50-ms noise bursts) from medial geniculate body, auditory cortex, and lateral amygdala (AMY), respectively, before and 2 hr post-SS. Note, 20 dB threshold shift of the functions to the right at low intensities (horizontal arrows) and large increase in response amplitude (up arrow) at suprathreshold levels (>60 dB SPL).