(A) Representative traces of whole-cell voltage clamp recordings, using a BAPTA-containing internal solution, of the outward current in D2S and D2L neurons induced by bath application of quinpirole … see more
(A) Representative traces of whole-cell voltage clamp recordings of the outward current induced by bath application of quinpirole (10 μM) that was reversed by sulpiride (600 nM), using a BAPTA or … see more
(A) The amplitude of the quinpirole (10 μM)-induced current using BAPTA+Ca2+ internal solution was not different from the amplitudes using BAPTA or EGTA internal solutions (n = 7–15, ANOVA followed … see more
(A) Representative trace of whole-cell voltage clamp recordings of the outward current induced by bath application of NS309 (10 μM), which was reversed by apamin (200 nM), using a BAPTA+Ca2+ … see more
(A) Representative traces of whole-cell voltage clamp recordings of the outward current in D2S and D2L neurons induced by bath application of quinpirole (30 μM) which was reversed by sulpiride (600 … see more
(A) In D2S neurons, the decline in quinpirole (30 μM)-induced current was greater using EGTA internal compared to BAPTA (n = 10–16). (B) In D2L neurons, the decline in quinpirole-induced current … see more
(A) Representative confocal microscopy images of Flag-D2S receptors clustered on the soma, dendrites, and spine-like structures of dopamine neurons, labeled by incubation of live slices in Alexa … see more
(A) In wild type neurons, CPA (10 μM, > 20 min) reduced the decline in the quinpirole-induced current using EGTA internal and the effect was prevented with the use of BAPTA internal (n = 11–15, … see more
(A) Submaximal D2 receptor-dependent outward currents (I-DA) were produced once every 50 s by iontophoretic application of dopamine while recording with EGTA internal. Prolonged CPA (10 μM) … see more
(A, B) In wild type neurons, isradipine (300 nM, > 20 min) had no significant effect on the decline in quinpirole-induced (A) and baclofen-induced current (B) recorded with EGTA and BAPTA internal … see more
(A) Submaximal D2 receptor-dependent outward currents (I-DA) were produced once every 50 s by iontophoretic application of dopamine while recording with EGTA internal. Prolonged isradipine (300 nM) … see more
(A) In neurons from cocaine-treated wild type mice using EGTA internal, the quinpirole-induced current declined less compared to naïve/saline-treated mice, to a level comparable to the decline … see more