Sensory experience modifies feature map relationships in visual cortex
- Australian College of Optometry, Australia
- University of Melbourne, Australia
- The University of Queensland, Australia
Figures
Figure 1
The elastic net model predicts changes in spatial map relationships under cross-rearing.
(a) Simulated orientation preference map (colours), orientation pinwheels (black dots), and ocular dominance borders (black lines) under normal rearing (relative strength of over-representation of …
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Figure 1—source data 1
This HDF5 file contains the numerical values shown in Figure 1.
- https://doi.org/10.7554/eLife.13911.004
Figure 2
Optical characteristics of the -10 dioptre cylindrical lenses.
(a) Circular square wave test grating (1 cycle/°) viewed normally (no lens). (b) The same grating viewed through the -10 dioptre cylindrical lens, with the lens axis aligned horizontally, …
Figure 3 with 3 supplements
Tuning properties of single units.
(a) The distribution of preferred orientation in control animals exhibited an over representation of cardinal orientations. The dashed line shows the expected distribution if all orientations were …
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Figure 3—source data 1
This HDF5 file contains the numerical values shown in Figure 3.
- https://doi.org/10.7554/eLife.13911.007
Figure 3—figure supplement 1
Inter-ocular difference in preferred orientation of single units is not altered by cross-rearing.
The mean inter-ocular difference in preferred orientation (ΔOP) is significantly greater than 0 in both control (mean ΔOP = 11.8°, p < 0.001, two-tailed t-test) and cross-reared animals (mean ΔOP = …
Figure 3—figure supplement 2
Preferred temporal frequency of single units is not altered by cross-rearing.
The distributions of preferred temporal frequency for single units from control and cross-reared animals are not significantly different (p = 0.2, Kruskal-Wallis test).
Figure 3—figure supplement 3
Contrast sensitivity of single units is not altered by cross-rearing.
The distributions of semi-saturation contrast (σ, see Equation 4) for single units from control and cross-reared animals are not significantly different (p = 0.81, Kruskal-Wallis test).
Figure 4
Extended spatial decorrelation recovers OP and OD maps from green light imaging.
(a) Time course of the relative change in reflectance (∆R/R) during a trial, averaged over all pixels and all trials, measured with red (609 nm) and green (520 nm) light. The shaded region shows the …
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Figure 4—source data 1
This HDF5 file contains the numerical values shown in Figure 4.
- https://doi.org/10.7554/eLife.13911.012
Figure 5 with 2 supplements
Cross-rearing changes the distribution of orientation preferences.
(a) OP map, (c) OD map and (e) overlay of OD and OP contours for a control cat. (b) OP map, (d) OD map and (f) overlay of OD and OP contours for a cross-reared cat. While qualitatively the control …
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Figure 5—source data 1
This HDF5 file contains the numerical values shown in Figure 5.
- https://doi.org/10.7554/eLife.13911.014
Figure 5—figure supplement 1
The distribution of orientation selectivity is slightly altered by cross-rearing.
The mean distributions of normalised orientation selectivity for all control and cross-reared hemispheres. Normalised orientation selectivity was calculated as the absolute value of each pixel in …
Figure 5—figure supplement 2
Distributions of orientation preferences in each hemisphere.
(a) Proportion of cortical area representing different orientations from binocular stimulation for all control hemispheres (colored lines), their mean (thin black line), and the best fitting sine …
Figure 6 with 2 supplements
Spatial relationship between pinwheels and ocular dominance is modified by rearing condition.
(a) Pinwheel density relative to squared map wavelength was not significantly different between control and cross-reared animals, both being consistent with the theoretically predicted value of π …
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Figure 6—source data 1
This HDF5 file contains the numerical values shown in Figure 6.
- https://doi.org/10.7554/eLife.13911.018
Figure 6—figure supplement 1
The distribution of intersection angles of the contours of the OP and OD maps is unchanged by cross-rearing.
(a) The distributions for control and cross-reared hemispheres are not significantly different (p = 0.36, two-sample Kruskal-Wallis test). For the quantification we used (see Materials and methods), …
Figure 6—figure supplement 2
The spatial layout of orientation selectivity is very slightly altered by cross-rearing.
The mean, normalised orientation selectivity in each of the five ocular dominance bins used to quantify pinwheel location relative to ocular dominance borders (see Materials and methods), averaged …
Author response image 1
