Blue areas depict independent ROIs used for beta-extraction overlaid on a canonical T1-weighted template (VS, HP) or the mean proton density normalized template from all subjects (SN/VTA). Bar graphs show mean beta coefficients within ROI for each condition of interest (M+ correct first sentence, M+ incorrect first sentence, M- correct first sentence, M- incorrect first sentence, M+ correct second sentence, M+ incorrect second sentence, M- correct second sentence, M- incorrect second sentence; the NR condition is shown as a control) with standard error of the mean (dark grey for M+; light grey for M-; white for NR). Paired t-test comparisons for all correct versus incorrect conditions revealed significant differences in all ROIs only for M+ correct versus incorrect trials during the second sentence presentation, when participants successfully learned the meaning of a new-word. L, Left Hemisphere; M+, congruent meaning extraction possible; M-, congruent meaning extraction impossible; NR, non-readable sentences; VS, Ventral Striatum; HP, Hippocampus; SN/VTA, Substantia Nigra/ Ventral Tegmental Area. ***p<0.001; **p<0.005.