Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points

  1. Uri Barenholz  Is a corresponding author
  2. Dan Davidi
  3. Eduard Reznik
  4. Yinon Bar-On
  5. Niv Antonovsky
  6. Elad Noor
  7. Ron Milo  Is a corresponding author
  1. The Weizmann Institute of Science, Israel
  2. The Weizmann Institute for Science, Israel
  3. Memorial Sloan Kettering Cancer Center, United States
  4. ETH Zurich, Switzerland
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  1. Uri Barenholz
  2. Dan Davidi
  3. Eduard Reznik
  4. Yinon Bar-On
  5. Niv Antonovsky
  6. Elad Noor
  7. Ron Milo
(2017)
Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points
eLife 6:e20667.
https://doi.org/10.7554/eLife.20667