Decoupled maternal and zygotic genetic effects shape the evolution of development
- New York University, United States
Abstract
Evolutionary transitions from indirect to direct development involve changes in both maternal and zygotic genetic factors, with distinctive population-genetic implications, but empirical data on the genetics of such transitions are lacking. The polychaete Streblospio benedicti provides an opportunity to dissect a major transition in developmental mode using forward genetics. Females in this species produce either small eggs that develop into planktonic larvae or large eggs that develop into benthic juveniles. We identify large-effect loci that act maternally to influence larval size and independent, unlinked large-effect loci that act zygotically to affect discrete aspects of larval morphology. The likely fitness of zygotic alleles depends on their maternal background, creating a positive frequency-dependence that may homogenize local populations. Developmental and population genetics interact to shape larval evolution.
Data availability
All code and data generated and analyzed during this study can be found in the supplemental files.
Article and author information
Author details
Funding
National Science Foundation (IOS-1350926)
- Matthew V Rockman
National Institutes of Health (GM108396)
- Christina Zakas
Zegar Family Foundation
- Matthew V Rockman
New York University (Biology Master's Research Grant)
- Alex D Kay
The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.
Copyright
© 2018, Zakas et al.
This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.
Metrics
-
- 2,471
- views
-
- 274
- downloads
-
- 22
- citations
Views, downloads and citations are aggregated across all versions of this paper published by eLife.
Download links
A two-part list of links to download the article, or parts of the article, in various formats.
Downloads (link to download the article as PDF)
Open citations (links to open the citations from this article in various online reference manager services)
Cite this article (links to download the citations from this article in formats compatible with various reference manager tools)
Decoupled maternal and zygotic genetic effects shape the evolution of development
eLife 7:e37143.
https://doi.org/10.7554/eLife.37143
