Anosognosia for hemiplegia as a tripartite disconnection syndrome
Figures

On the top half, statistical mapping of the lesioned areas in AHP.
(a) right hemisphere (b) striatum (c) insula (d) axial sections. Pal: pallidum; Put: putamen; ALg: anterior long gyrus; PSg: posterior short gyrus; MSg: middle short gyrus; Tp: temporal pole. On the bottom half, statistical mapping of the brain disconnections in AHP. (e) right hemisphere lateral view; (f) right hemisphere medial view; (g) axial sections. TPJ: temporo-parietal junction; VPF: ventral prefrontal cortex; preSMA: pre-supplementary area; H: hippocampus; Cing: cingulum; SLF III: third (ventral) branch of the superior longitudinal fasciculus; PreSMA: pre-supplementary motor area.

Motor awareness network.
(a) right hemisphere medial view (left) right hemisphere lateral view (right); (b-c) Bayes Factors for all models, each one representing the hypothesis that the damage to grey matter structure and/or the tract disconnection is necessary to explain AHP, against the clinical/demographic model. Ins: insula; TP: temporal pole; Put: putamen; FST: fronto-striatal tract; Cing: cingulum; FAT: frontal aslant tract; SLF III: third branch of the superior longitudinal fasciculus.
Tables
For AHP and control groups, mean and (±standard deviation) of demographic and clinical variables, neurological and neuropsychological assessments are reported.
https://doi.org/10.7554/eLife.46075.004Ahp (N = 95) | Hp (N = 79) | |
---|---|---|
Demographic and clinical | ||
Age (years) | 68.48 ± 12.54 | 63,01 ± 13.49 |
Education (years) | 9.46 ± 3.74 | 11 ± 3.77 |
Interval (days) | 35.74 ± 40.58 | 44.42 ± 46.7 |
Lesion Size (voxels) | 134327.74 ± 113196.17 | 113082.73 ± 120844.22 |
Anosognosia | ||
Bisiach score | 2.46 ± 0.6 | 0 ± 0 |
Personal neglect | ||
Comb | −0.3 ± 0.4 | −0.06 ± 0.47 |
Extra-personal neglect | ||
Line cancellation (number of items cancelled) | 19.26 ± 11.9 | 28.35 ± 10.77 |
Memory Span | ||
Digit/verbal span (number of items recalled) | 5.65 ± 2.14 | 6.83 ± 2.46 |
Motor index | ||
MRC (LUL) | 0.15 ± 0.42 | 0.6 ± 0.99 |
Additional files
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Source data 1
- https://doi.org/10.7554/eLife.46075.005
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Transparent reporting form
- https://doi.org/10.7554/eLife.46075.006