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Görkem Patir-Nebioglu M, Andrés Z, Krebs M, Fink F, Drzewicka K, Stankovic-Valentin N, Segami S, Schuck S, Büttner M, Hell R, Maeshima M, Melchior F, and Schumacher K. 2019. Pyrophosphate modulates plant stress responses via SUMOylation. eLife 8:e44213. doi: 10.7554/eLife.44213.

Published 20, February 2019

The authors are retracting the eLife paper cited above based on irregularities associated with the western blots shown in Figures 3D and E as well as Figures 4C and D performed by Gorkem Patir-Nebioglu (GPN). Initiated by reports on PubPeer, the authors have investigated the matter and have found that in both Figures 3 and 4 the blots were spliced together from different original images without indication and a single lane was copied twice in Figure 3E. In addition, GPN has admitted to having intentionally loaded less protein for fugu5 at 4°C (Figure 3) and 40°C (Figure 4). The authors are currently running independent repetitions of the experiments in question and hope to be able to provide appropriate data in the near future. However, with the currently available data, the conclusion that SUMOylation is reduced in fugu5 mutants is not justified and all authors have agreed to retract the paper.

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Author details

  1. M Görkem Patir Nebioglu

  2. Melanie Krebs

  3. Fabian Fink

  4. Katarzyna Drzewicka

  5. Nicolas Stankovic-Valentin

  6. Shoji Segami

  7. Michael Büttner

  8. Masayoshi Maeshima

Version history

  1. Version of Record published: March 26, 2019 (version 1)


© 2019, Patir Nebioglu et al.

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.


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  1. M Görkem Patir Nebioglu
  2. Zaida Andrés
  3. Melanie Krebs
  4. Fabian Fink
  5. Katarzyna Drzewicka
  6. Nicolas Stankovic-Valentin
  7. Shoji Segami
  8. Sebastian Schuck
  9. Michael Büttner
  10. Rüdiger Hell
  11. Masayoshi Maeshima
  12. Frauke Melchior
  13. Karin Schumacher
Retraction: Pyrophosphate modulates plant stress responses via SUMOylation
eLife 8:e46993.

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