(A) Known dimers of Drosophila C/EBP –class bZip proteins and their potential functions. (B,C) Mitotic recombination in RpL36+/+ wing discs (grey) generates clones of RpL36+/+/+ cells (light grey) …
Measurements of clone and wing pouch sizes corresponding to Figure 1F.
Clone size data corresponding to Figure 1I.
(A) In the TIE-DYE method, independent recombination events generate parallel clones expressing GFP (green), Gal4 (detected through UAS-RFP expression in red), and b-Gal (blue). These parallel …
Source data for the graph shown in Figure 2E.
Source data for the graph shown in Figure 2F.
(A,B) Xrp1 protein (labeled in B) is elevated in RpS18+/- cells (green in A) compared to RpS18+/+ cells (unlabelled in A). (C,D) Irbp18 protein (labeled in D) is elevated in RpS18+/- cells (green in …
(A) Sequential modifications of the Xrp1 locus in the 18925–18926 kb region of chromosome arm 3R by homologous recombination, Cre recombination and PhiC31 integration introduced modified and …
(A) As clones of RpS18+/+ cells (unlabelled) expand to occupy most of a RpS18+/- wing imaginal disc (green, GFP labeling), apoptosis is elevated especially at the boundaries between the cells …
(A) Wing imaginal discs containing clones of control cells lacking b-galactosidase (magenta) and reciprocal clones expressing GFP (green). In panels B-D) Xrp1 is co-expressed with GFP. Xrp1 led to …
Most panels show adult eyes where GMR-Gal4 has been used to express the indicated proteins and dsRNAs posterior to the morphogenetic furrow. Temperature was 25°C except where indicated otherwise. …
(A) GMR-Gal4 drives UAS-GFP expression (green) posterior to the morphogenetic furrow in the eye imaginal disc. An antibody specific for the Xrp1 long isoform detects co-expressed Xrp1 protein …
(A–L) Over-expression of Xrp1 proteins during wing development using nub-Gal4 at 18°C. A,C,E,G,I,K show wings from males misexpressing the indicated proteins. Results were similar from females …
(A) Scanning Electron Micrograph (SEM) of male GMR-Gal4/+ eye, raised at 25°C. Morphology is almost wild type (compare Figure 7M). (B) At 25°C, expression of the Xrp11-546 protein that lacks the …
(A) PAML results for 12 Drosophila species showing the location of sites under strong positive selection in the Xrp1 protein. (B) The conservation (% amino-acid identity to Xrp1 from Drosophila …
Key Resources.