Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    NR2F2 is required in the embryonic testis for Fetal Leydig Cell development

    Aitana Perea-Gomez, Natividad Bellido-Carreras ... Marie-Christine Chaboissier
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology

    An increase in reactive oxygen species underlies neonatal cerebellum repair

    Anna Pakula, Salsabiel El Nagar ... Alexandra L Joyner
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen
    Not revised
    Reviewed Preprint v1
    1. Computational and Systems Biology
    2. Developmental Biology

    Diversity in Notch ligand-receptor signaling interactions

    Rachael Kuintzle, Leah A Santat, Michael B Elowitz
    The Notch signaling pathway can use its various ligands, receptors, and Fringe proteins to generate diverse intra- and intercellular signaling behaviors.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling

    Kara A Nelson, Kari F Lenhart ... Stephen DiNardo
    A new example of niche formation, revealing the mode of niche cell migration, implicates extrinsic sources of positional information, and uncovers the pathway required for stereotypical positioning of the niche.
    1. Developmental Biology

    Reconstruction of functional olfactory sensory tissue from embryonic nasal stem cells

    Kazuya Suzuki, Fumi Wagai, Mototsugu Eiraku
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling

    Elise S Bruguera, Jacob P Mahoney, William I Weis
    Biophysical binding and structural prediction studies reveal that Tetraspanin12 directly binds the ligand Norrin, in a manner that is negatively cooperative with Norrin-Fzd4 binding and competitive with Norrin-LRP5/6 binding.
    1. Developmental Biology

    Opposing roles for Bmp signalling during the development of electrosensory lateral line organs

    Alexander S Campbell, Martin Minařík ... Clare VH Baker
    1. Developmental Biology

    Flamingo participates in multiple models of cell competition

    Pablo Sanchez Bosch, Bomsoo Cho, Jeffrey D Axelrod
    In Drosophila, the planar cell polarity protein Flamingo is required by winners to maintain their status during cell competition in multiple models as they compete to occupy excessive territory within wildtype tissues.
    1. Developmental Biology
    2. Genetics and Genomics

    Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

    Stephen A Banse, Christine A Sedore ... Patrick C Phillips
    Not revised
    Reviewed Preprint v1
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Highlights

    1. Developmental Biology

    Patterning the neural plate

    Margaret Hines, Elias Oxman ... Irene Zohn
    1. Developmental Biology

    Signaling pathways in the lung

    Nathaniel C Nelson, Matthias C Kugler
    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Claude Desplan
    New York University, United States
  3. Didier Stainier
    Max Planck Institute for Heart and Lung Research, Germany
  4. See more editors