Developmental Biology

Latest articles

1. 1. Developmental Biology

   Morphogenesis: Regulating closure of the neural tube in humans

   Leon Qarawani, Jacob H Hanna

   An organoid-based screening platform that allows one-gene-at-a-time knockdown across a whole tissue has been used to identify the genes that regulate closure of the neural tube in humans.
2. 1. Developmental Biology
   2. Neuroscience

   Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function

   Caleb CS Calhoun, Mary ES Capps ... Summer B Thyme
3. 1. Developmental Biology

   Extracellular adenosine deamination primes tip organizer development in Dictyostelium

   Pavani Hathi, Baskar Ramamurthy
4. 1. Cell Biology
   2. Developmental Biology

   The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice

   Atsuko Kageyama, Narumi Ogonuki ... Junya Ito
5. 1. Cell Biology
   2. Developmental Biology

   Gene regulatory mechanisms guiding bifurcation of inhibitory and excitatory neuron lineages in the mouse anterior brainstem

   Sami Kilpinen, Lassi Virtanen ... Juha Partanen

   Changes of the chromatin structure suggests how the fate selector transcription factors are activated and how they guide differentiation of GABAergic and glutamatergic neurons in the anterior brainstem.
6. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

   David W Wolfson, Joshua A Hull ... Kenneth D Poss

   Bioluminescence imaging in live mice was used to assess the abilities of systemically introduced adeno-associated viral capsids containing enhancer regulatory sequences to target transgene expression to myocardial injuries.
7. 1. Developmental Biology

   A cell atlas of the developing human outflow tract of the heart and its adult derivatives

   Rotem Leshem, Syed Murtuza Baker ... Nicoletta Bobola
8. 1. Cancer Biology
   2. Developmental Biology

   Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

   Denise Ragusa, Chun Wai Suen ... Cristina Pina

   The hemogenic gastruloid model of embryonic blood development captures multi-wave haematopoiesis and enables interrogation of infant leukaemia cell-of-origin.
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration

   Yue Lu, Tezin Walji ... Elizabeth H Chen
10. 1. Developmental Biology
    2. Genetics and Genomics

    A genome-wide MAGIC kit for recombinase-independent mosaic analysis in Drosophila

    Yifan Shen, Ann T Yeung ... Chun Han