Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs

    Çağrı Çevrim, Béryl Laplace-Builhé ... Michalis Averof
    Live imaging allows tracking cellular behaviours and cell fates during the entire course of leg regeneration, spanning approximately one week, in a crustacean model.
    1. Developmental Biology

    Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants

    Rebecca G Jaszczak, Jay W Zussman ... Diana J Laird
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Characterisation of cell-scale signalling by the core planar polarity pathway during Drosophila wing development

    Alexandre Carayon, Helen Strutt, David Strutt
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Developmental Biology

    Molecular and mechanical signatures contributing to mouse epidermal differentiation and barrier formation

    Alexandra Prado-Mantilla, Wenxiu Ning, Terry Lechler
    The roles of intermediate cells and contractility are characterized in the embryonic development of the epidermis.
    1. Developmental Biology
    2. Genetics and Genomics

    Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes

    Stephen A Banse, Christine A Sedore ... Patrick C Phillips
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    Cytoneme-mediated intercellular signaling in keratinocytes is essential for epidermal remodeling in zebrafish

    Yi Wang, Thomas Nguyen ... Dae Seok Eom
    Keratinocyte cytonemes mediate essential Notch signaling for proper skin maintenance, with their disruption leading to abnormal differentiation and hyperproliferation resembling human skin disease phenotypes.
    1. Developmental Biology

    Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features

    Dominic WH Shayler, Kevin Stachelek ... David Cobrinik
    Full-length single-cell RNA-sequencing provide insights into the earliest gene expression programs, the distinct mRNA transcript isoforms, and the retinoblastoma-related cell states associated with human cone and rod photoreceptor development.
    1. Developmental Biology

    ANKRD5: a key component of the axoneme required for sperm motility and male fertility

    Shuntai Yu, Guoliang Yin ... Fengchao Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry

    Fanny Eggeler, Jonathan Boulanger-Weill ... Filippo Del Bene
    Genetic analyses in zebrafish reveal a new role for the Meteorin protein family in the left-right asymmetry patterning during embryonic vertebrate development.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians

    Ryan A McCubbin, Mohammad A Auwal ... Ricardo M Zayas
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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Highlights

    1. Developmental Biology
    2. Neuroscience

    Ribbon synapses in zebrafish

    Satish R Ghimire, Thomas M Coate
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Targeting cardiac repair

    Stanislao Igor Travisano, Ching-Ling Lien
    1. Developmental Biology

    Special Issue: Reproductive health

    Wei Yan

Senior editors

  1. Claude Desplan
    New York University, United States
  2. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors