Developmental Biology

Developmental Biology

eLife publishes research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Notch controls the cell cycle to define leader versus follower identities during collective cell migration

    Zain Alhashem et al.
    Computational modelling and experimental manipulation show that Notch signalling regulates collective cell migration by allocating distinct migratory identities through the control of cell cycle progression.
    1. Cancer Biology
    2. Developmental Biology

    Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects

    Maja Solman et al.
    The transcriptomes of hematopoietic stem and progenitor cells of human juvenile myelomonocytic leukemia patients and a zebrafish model for Noonan syndrome reveal a common inflammatory response, which may have a causal role in associated myeloproliferative neoplasm.
    1. Developmental Biology

    Distinct responses to rare codons in select Drosophila tissues

    Scott R Allen et al.
    A tissue-wide fluoresence-based screen reveals that not all tissues in an organism (Drosophila) reinforce a hierarchy of codon usage to the same extent, a finding which impacts tissue-specific protein expression and function.
    1. Developmental Biology
    2. Medicine

    VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development

    Derek C Sung et al.
    VE-cadherin is required for trophoblast invasion of the maternal decidua and spiral arteries.
    1. Developmental Biology
    2. Immunology and Inflammation

    A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells

    David J Turner et al.
    A genetic screening approach identifies RNA binding proteins that enhance or inhibit the accumulation of CD138+ plasma cells in vitro, and chimeric mouse models demonstrate that YTHDF2 promotes the accumulation of antibody secreting cells in vivo.

Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Claude Desplan
    New York University, United States
  3. Mike Eisen
    Michael B Eisen
    HHMI, University of California, Berkeley, United States
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