Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Massively parallel reporter assay for mapping gene-specific regulatory regions at single nucleotide resolution

    Alastair J Tulloch, Ryan N Delgado ... Constance L Cepko
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

    Sen-Lin Lai, Chris Q Doe
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Mouse germline cysts contain a fusome that mediates oocyte development

    Madhulika Pathak, Allan C Spradling
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Developmental Biology

    Limb Patterning: The cellular logic of limb regeneration

    Matthew Cherubino, Catherine D McCusker
    Hierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.
    Version of Record
    Insight
    1. Developmental Biology

    Patient-specific iPSC models of neural tube defects identify underlying deficiencies in neuroepithelial cell shape regulation and differentiation

    Ioakeim Ampartzidis, Elliott M Thompson ... Gabriel L Galea
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Human spinal cord organoids reveal cell intercalation as a conserved mechanism for secondary neurulation

    José Blanco-Ameijeiras, Yara El Majzoub ... Elisa Martí
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Computational and Systems Biology
    2. Developmental Biology

    Anti-resonance in developmental signaling regulates cell fate decisions

    Samuel J Rosen, Olivier Witteveen ... Maxwell Z Wilson
    Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is capable of redirecting developmental fate outcomes, including germ-layer specification.
    1. Developmental Biology

    Permissive and instructive Hox codes govern limb positioning

    Yajun Wang, Maik Hintze ... Ruijin Huang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Bruce suppresses autophagy-regulated caspase activity and wing tissue growth in Drosophila

    Natsuki Shinoda, Yutaro Hama ... Masayuki Miura
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Progressive mural cell deficiencies across the lifespan in a foxf2 model of Cerebral Small Vessel Disease

    Merry Faye E Graff, Emma EM Heeg ... Sarah J Childs
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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Highlights

    1. Developmental Biology

    Positional cues and limb regeneration

    Matthew Cherubino, Catherine D McCusker
    1. Developmental Biology

    Special Issue: Reproductive health

    Wei Yan
    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer

Senior editors

  1. Albert Cardona
    University of Cambridge, United Kingdom
  2. Didier Stainier
    Max Planck Institute for Heart and Lung Research, Germany
  3. Richard M White
    Ludwig Institute for Cancer Research, University of Oxford, United Kingdom
  4. See more editors