Developmental Biology

Latest articles

1. 1. Cell Biology
   2. Developmental Biology

   Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition

   Yuhkoh Satouh, Takaki Tatebe ... Ken Sato
2. 1. Developmental Biology
   2. Chromosomes and Gene Expression

   Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

   Peng Xie, Xu Jiang ... Chengqi Lin
3. 1. Developmental Biology
   2. Chromosomes and Gene Expression

   The transcriptional landscape underlying larval development and metamorphosis in the Malabar grouper (Epinephelus malabaricus)

   Roger Huerlimann, Natacha Roux ... Timothy Ravasi
4. 1. Developmental Biology
   2. Neuroscience

   A unique multi-synaptic mechanism involving acetylcholine and GABA regulates dopamine release in the nucleus accumbens through early adolescence in male rats

   Melody C Iacino, Taylor A Stowe ... Mark J Ferris

   A circuit within the nucleus accumbens that exists during a specific developmental window through early adolescence male rats may serve as a substrate that underlies heightened reward seeking in this population.
5. 1. Developmental Biology
   2. Medicine

   SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction

   Stephen E Flaherty III, Olivier Bezy ... Zhidan Wu

   Investigation of mouse models from forward mutagenetic screen reveals that the gene Spag7 is essential for embryonic development and energy homeostasis later in life.
6. 1. Developmental Biology
   2. Genetics and Genomics

   The role of heterochronic gene expression and regulatory architecture in early developmental divergence

   Nathan D. Harry, Christina Zakas
7. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Temporally resolved early bone morphogenetic protein-driven transcriptional cascade during human amnion specification

   Nikola Sekulovski, Jenna C Wettstein ... Kenichiro Taniguchi

   Analyses of transcriptomic dynamics in a new model of human amnion formation identify five continuous amniogenic transcriptional phases as well as a critical role of TFAP2A in amnion fate progression.
8. 1. Developmental Biology

   Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation

   Yifan Wu, Kunhua Qin ... Pei Wang

   Loss of YAP1/TAZ expression in the pancreatic endocrine compartment is not a passive consequence of endocrine specification, rather, Hippo pathway-mediated inhibition of YAP1/TAZ in endocrine progenitors is a prerequisite for endocrine specification and differentiation.
9. 1. Developmental Biology
   2. Neuroscience

   Spatiotemporal changes in Netrin/Dscam1 signaling dictate axonal projection direction in Drosophila small ventral lateral clock neurons

   Jingjing Liu, Yuedong Wang ... Yao Tian

   Dynamic local microenvironments in Drosophila facilitate axonal projection direction transitions in the absence of clear landmarks.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz