Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Neuroscience

    Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model

    Sergi Llambrich, Birger Tielemans ... Greetje Vande Velde
    Ts65dn mice exhibit structural, functional, molecular, and genetic alterations that are modulated but unrecovered by prenatal chronic GTE-EGCG, highlighting the importance of holistic studies to understand complex disorders and treatments.
    1. Developmental Biology

    Tmc7 deficiency causes acrosome biogenesis defects and male infertility in mice

    Jing Wang, Yingying Yin ... Zhaojian Liu
    1. Developmental Biology
    2. Neuroscience

    Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival

    Guangqin Wang, Yunpeng Gu, Zhiyong Liu
    Rbm24 is controlled by Pou4f3 but not Gfi1 during cochlear hair cell development.
    1. Developmental Biology
    2. Evolutionary Biology

    A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis

    Jaaved Mohammed, Neha Arora ... Joanna Wysocka
    SNP-editing of human embryonic stem cells reveals cell type specific function of a genetic variant associated with changes in human jaw shape.
    1. Cell Biology
    2. Developmental Biology

    Ciliary length regulation by intraflagellar transport in zebrafish

    Yi Sun, Zhe Chen ... Chengtian Zhao
    1. Developmental Biology

    FBXO24 modulates mRNA alternative splicing and MIWI degradation and is required for normal sperm formation and male fertility

    Zhiming Li, Xingping Liu ... Shuiqiao Yuan
    Animal models and molecular data reveal how FBXO24 regulates mRNA expression and MIWI degradation in the round spermatids.

Highlights

    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer
    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Albert Cardona
    University of Cambridge, United Kingdom
  3. Lois Smith
    Harvard Medical School, Children's Hospital Boston, United States
  4. See more editors