Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Trehalose metabolism regulates transcriptional control of muscle development in lepidopteran insects

    Sharada Mohite, Tanaji Devkate ... Rakesh Shamsunder Joshi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD

    Uyen Tran, Andrew J Streets ... Oliver Wessely
    The RNA-binding protein BICC1 can act as a genetic disease modifier for kidney cyst formation, potentially explaining the high variability of disease onset and severity in autosomal-dominant polycystic kidney disease patients.
    1. Developmental Biology
    2. Genetics and Genomics

    Equity, Diversity and Inclusion: Four women whose pioneering contributions to science have been largely overlooked

    Lisa M Thomann, Julie Batut
    Ethel Browne Harvey, Hilde Pröscholdt Mangold, Ida Henrietta Hyde and Marthe Gautier all made important contributions to developmental biology, but their names are largely absent from histories of science.
    1. Developmental Biology
    2. Genetics and Genomics

    PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development

    Julia Raulino Lima, Nicha Ungvijanpunya ... Jian Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology

    map3k1 is required for spatial restriction of progenitor differentiation in planarians

    Bryanna Isela-Inez Canales, Hunter O King, Peter W Reddien
    map3k1 inhibits progenitor differentiation until suitable positional cues are acquired as a mechanism of pattern formation.
    1. Developmental Biology

    Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions

    Sunayana Sarkar, Harsha Sharma ... Manish Jaiswal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology

    Mouse skeletal muscle satellite cells co-opt the tenogenic gene Scleraxis to instruct regeneration

    Yun Bai, Tyler Harvey ... Chen-Ming Fan
    Muscle stem cells repurpose the tenogenic factor Scx to establish a muscle-specific transcriptional program that sustains stem cell expansion, migration, differentiation, fusion, self-renewal, and survival.
    1. Developmental Biology

    Imp1 acts as a dosage- and stage-dependent temporal rheostat orchestrating radial glial fate transitions and cortical morphogenesis

    Romie Angelo G Azur, Daniel Feliciano ... Tzumin Lee
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels

    Kurt Weir, Pin Lyu ... Seth Blackshaw
    Upregulated expression of transcription factors promoting cone identity in late-stage retinal progenitors drives development of the cone-dominant retina of 13-lined ground squirrels.
    1. Developmental Biology

    Dorsoventral-mediated Shh induction is required for axolotl limb regeneration

    Sakiya Yamamoto, Saya Furukawa ... Akira Satoh
    Dorsoventral contact in axolotl limb blastemas induces Shh, showing how positional identities cooperate to drive the regeneration process.

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors