Developmental Biology

Latest articles

1. 1. Cell Biology
   2. Developmental Biology

   Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages

   Weng Man Chong et al.
2. 1. Developmental Biology
   2. Neuroscience

   Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches

   Branden R Nelson et al.
3. 1. Developmental Biology

   LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility

   Hyang Mi Moon et al.

   Novel insights into LIS1-dependent regulation of cell membrane contractility and cleavage axis specification identify a key molecular network regulating mitoses of neural progenitors and somatic cells during development.
4. 1. Developmental Biology

   Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin

   Taifeng Zhou et al.

   Mechanosensitive channels Piezo1/2 are required for osteoblast differentiation from progenitors by sensing fluid sheer stress and matrix rigidity and regulating NFATc1, YAP1 and ß-catenin activities through Ca²⁺ stimulated phosphatase calcineurin.
5. 1. Developmental Biology
   2. Human Biology and Medicine

   Mutations associated with human neural tube defects display disrupted planar cell polarity in Drosophila

   Ashley C Humphries et al.
6. 1. Developmental Biology
   2. Neuroscience

   Application of optogenetic Amyloid-β distinguishes between metabolic and physical damage in neurodegeneration

   Chu Hsien Lim et al.
7. 1. Cell Biology
   2. Developmental Biology

   Fibronectin is a smart adhesive that both influences and responds to the mechanics of early spinal column development

   Emilie Guillon et al.

   A fibronectin matrix constantly remodels to the area of highest mechanical stress, and the resulting fibronectin-mediated inter-tissue adhesion impedes neural tube convergence.
8. 1. Developmental Biology

   Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling

   Hua Shen et al.

   Neonatal mouse heart regeneration relies on the presence of mononuclear diploid cardiomyocytes, which unites this process with embryonic heart growth and adult heart regeneration.
9. 1. Developmental Biology
   2. Neuroscience

   Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex

   Ayse Güven et al.

   Transcription factor Sox9 has an important role in neocortex expansion, where its expression in basal progenitors increases proliferation, induces premature gliogenesis and promotes the expression of extracellular matrix components.
10. 1. Developmental Biology

    A branched heterochronic pathway directs juvenile-to-adult transition through two LIN-29 isoforms

    Chiara Azzi et al.

    Distinct regulation endows two isoforms of the transcription factor LIN-29 with distinct functions to achieve coordinated execution of separate juvenile-to-adult transition events in Caenorhabditis elegans..