Developmental Biology

Latest articles

1. 1. Developmental Biology

   Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation

   Rodrigo M Young et al.

   The inclusion of a new alternatively spliced exon in Tcf7l2 can switch its function to repress transcription of Wnt target genes.
2. 1. Developmental Biology
   2. Human Biology and Medicine

   Prolonged ovarian storage of mature Drosophila oocytes dramatically increases meiotic spindle instability

   Ethan J Greenblatt et al.

   Meiotic chromosome segregation in mature Drosophila oocytes is sensitive to prolonged quiescence, suggesting that human oocyte instability may result from storage of mature rather than primordial oocytes and be modifiable.
3. 1. Cell Biology
   2. Developmental Biology

   Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila

   Jean-André Lapart et al.

   Genetic analyses in Drosophila establish the functional hierarchy of the ciliary transition zone module, Dzip1/Fam92/Cby, and reveal tissue specific variations in basal body anchoring pathways in fly ciliated tissues.
4. 1. Developmental Biology
   2. Neuroscience

   Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis

   Youngsik Woo et al.
5. 1. Developmental Biology
   2. Human Biology and Medicine

   Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease

   Daniyal J Jafree et al.
6. 1. Developmental Biology
   2. Neuroscience

   Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

   Max Koppers et al.

   Multiple axonal guidance receptors control the local and selective translation of mRNAs by binding to ribosomes, specific mRNAs and RNA-binding proteins.
7. 1. Developmental Biology
   2. Neuroscience

   Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans

   Menghao Lu, Kota Mizumoto

   Genetic analyses revealed the critical role of local Wnt in neuronal patterning by instructing neurite pruning.
8. 1. Developmental Biology
   2. Neuroscience

   Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth

   Ryan T Willett et al.

   The first born excitatory cerebellar nuclei neurons influence the survival of their Purkinje cell partners which stimulate the expansion of granule cells and interneurons to produce functional local circuits.
9. 1. Developmental Biology
   2. Plant Biology

   Coordination of tissue cell polarity by auxin transport and signaling

   Carla Verna et al.

   GNOM controls both auxin transport and auxin signaling to coordinate tissue cell polarity during vein patterning in plants.
10. 1. Developmental Biology
    2. Microbiology and Infectious Disease

    High fat diet induces microbiota-dependent silencing of enteroendocrine cells

    Lihua Ye et al.