Developmental Biology

Developmental Biology

eLife publishes research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion

    Naokazu Inoue et al.
    Mammalian fertilization is accomplished through integrating various molecular pathways that include evolutionarily conserved factors, DCST1 and DCST2.
    1. Developmental Biology

    Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice

    Georges Raad et al.
    Predisposition to obesity-associated diseases is dependent on the ancestors' diet.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra

    Jack F Cazet et al.
    Injuries activate the oral identity-specifying canonical Wnt signaling pathway in Hydra, which can trigger head regeneration in permissive tissue contexts created by the absence of pre-existing organizers.
    1. Developmental Biology
    2. Genetics and Genomics

    Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose

    Zhejun Ji et al.
    Cell competition is an important mechanism selecting against aneuploid cells.
    1. Developmental Biology

    In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration

    Mira I Pronobis et al.
    Proximity labeling-based proteomic strategies applied in zebrafish identify new insights into protein network changes in heart muscle cells during regeneration and implicate Rho A as a target of ErbB2 signaling during zebrafish heart regeneration.
    1. Cell Biology
    2. Developmental Biology

    The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium

    Patrick Morley Willoughby et al.
    Rab25a and Rab25b mutant embryos exhibit epithelial spreading delays during morphogenesis and are characterized by cytokinesis defects leading to cell fusions, heterogeneous epithelial cell sizes, and reduced cortical actomyosin contractility.

Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Mike Eisen
    Michael B Eisen
    HHMI, University of California, Berkeley, United States
  3. Edward Morrisey
    University of Pennsylvania, United States
  4. See more editors