Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration

    Edgar M Pera, Josefine Nilsson-De Moura ... Ivana Milas
    An extracellular proteolytic pathway involving the serine protease HtrA1, its inhibitor SerpinE2, and the transmembrane proteoglycan Syndecan-4 control collective migration of neural crest cells in the developing embryo.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    N-Terminus of Drosophila Melanogaster MSL1 Is Critical for Dosage Compensation

    Valentin Babosha, Natalia Klimenko ... Oksana Maksimenko
    1. Developmental Biology
    2. Genetics and Genomics

    ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse

    Debashish U. Menon, Prabuddha Chakraborty ... Terry Magnuson
    1. Developmental Biology
    2. Neuroscience

    Fetal influence on the human brain through the lifespan

    Kristine B Walhovd, Stine K Krogsrud ... Didac Vidal-Pineiro
    Greater early developmental growth, as indexed by birth weight, relates to greater cortical volume and area in a stable way through the human lifespan.
    1. Developmental Biology
    2. Immunology and Inflammation

    Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis

    Amir Hossein Kayvanjoo, Iva Splichalova ... Elvira Mass
    Identification of distinct yolk sac-derived macrophage subpopulations in the fetal liver reveals their crucial role in shaping the hematopoietic niche, impacting erythropoiesis and granulopoiesis through direct interactions with long-term hematopoietic stem cells.
    1. Developmental Biology
    2. Neuroscience

    Dysregulation of mTOR signaling mediates common neurite and migration defects in both idiopathic and 16p11.2 deletion autism neural precursor cells

    Smrithi Prem, Bharati Dev ... Emanuel DiCicco-Bloom
    Alterations in mTOR signaling drive similar dysregulations in the critical mid-fetal neurodevelopmental processes of neurite outgrowth and cell migration in two distinct subsets of autism, idiopathic and 16p11.2 deletion.

Highlights

    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer
    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Didier Stainier
    Max Planck Institute for Heart and Lung Research, Germany
  4. See more editors