Developmental Biology

Latest articles

1. 1. Developmental Biology

   Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea

   Takefumi Kondo, Shigeo Hayashi

   The Drosophila tracheal fate is stabilized by the combination of transcriptional programs to control tissue architecture and tissue-level input sensitive to tubular geometry, ensuring the robust mechanism of organ determination.
2. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish

   Shuguang Yu, Jie He

   The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.
3. 1. Developmental Biology

   Suppression of transcytosis regulates zebrafish blood-brain barrier function

   Natasha M O'Brown et al.
4. 1. Cell Biology
   2. Developmental Biology

   CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity

   Myo-Hyeon Park et al.
5. 1. Developmental Biology
   2. Structural Biology and Molecular Biophysics

   A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity

   Chen Qiu et al.

   A Caenorhabitis elegans RNA-binding protein, FBF-2, modulates RNA sequence motif recognition through conformational change and partner protein interaction.
6. 1. Developmental Biology
   2. Evolutionary Biology

   The alternative regenerative strategy of bearded dragon unveils the key processes underlying vertebrate tooth renewal

   Lotta Salomies et al.
7. 1. Developmental Biology
   2. Genetics and Genomics

   Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network

   Yamila N Torres Cleuren et al.
8. 1. Developmental Biology
   2. Neuroscience

   Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2

   Verity Johnson et al.

   ROBO isoforms with minute sequence variations have significant and distinct functions in axon guidance.
9. 1. Developmental Biology

   Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

   Weiyi Tang et al.
10. 1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration

    Zhihao Jia et al.

    Inhibition of Polo-like kinase that has been shown to exhibit antitumor effect unexpectedly disrupts muscle stem cell function, leading to developmental and regenerative failures.