Developmental Biology

Latest articles

1. 1. Cancer Biology
   2. Developmental Biology

   VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300

   Susu Guo, Xiaodi Hu ... Junhao Mao

   Characterization of recurrent fusion proteins in rhabdomyosarcoma identified a Hippo pathway-independent mechanism involving VGLL2 and TEAD1 driving oncogenic transformation.
2. 1. Developmental Biology

   Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

   Madeline M Keenen, Liheng Yang ... Carolyn B Coyne
3. 1. Cell Biology
   2. Developmental Biology

   Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

   Qian Wang, Hongge Li ... Xin Zhang

   FGF signaling drives lens development by recruiting Grb2 through Shc1, Frs2, and Shp2 to regulate transcription and cytoskeletal arrangements.
4. 1. Developmental Biology
   2. Evolutionary Biology

   Differences in size and number of embryonic type II neuroblast lineages correlate with divergent timing of central complex development between beetle and fly

   Simon Rethemeier, Sonja Fritzsche ... Vera S Hunnekuhl

   Genetic labeling and molecular analyses characterize the dynamics of embryonic central complex-forming type II neuroblast lineages in Tribolium castaneum.
5. 1. Cell Biology
   2. Developmental Biology

   Cell Signaling: Not all dimers are equal

   Jeet H Patel, Mary C Mullins

   Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.
6. 1. Developmental Biology

   Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

   Pengzhen Dong, Yue Li ... Hai Huang
7. 1. Cell Biology
   2. Developmental Biology

   Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes

   Pavan K Nayak, Arul Subramanian, Thomas F Schilling

   Muscle contraction forces shape tenocyte gene expression, with sequencing and spatial analyses revealing unique force-dependent gene regulation patterns, suggesting tenocytes fine-tune tendon matrix in response to varied mechanical cues.
8. 1. Developmental Biology

   An atypical basement membrane forms a midline barrier during left-right asymmetric gut development in the chicken embryo

   Cora Demler, John C Lawlor ... Natasza A Kurpios

   A novel midline barrier is discovered in the developing gut, highlighting its dynamics and function, with broad implications for patterning mechanisms, extracellular matrix significance, and laterality disorders.
9. 1. Developmental Biology

   The epididymis contributes to sperm DNA integrity and early embryo development through Cysteine-Rich Secretory Proteins

   Valeria Sulzyk, Ludmila Curci ... Patricia S Cuasnicu

   The identification of epididymal proteins relevant for sperm DNA integrity and early embryo development will contribute to a better understanding, diagnosis, and treatment of human infertility.
10. 1. Developmental Biology
    2. Neuroscience

    In mice, discrete odors can selectively promote the neurogenesis of sensory neuron subtypes that they stimulate

    Kawsar Hossain, Madeline Smith ... Stephen W Santoro