Developmental Biology

Latest articles

1. 1. Developmental Biology

   mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

   Soyeon Lim et al.
2. 1. Developmental Biology
   2. Neuroscience

   Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis

   Tania Moreno-Mármol et al.

   Retinal pigment epithelium flattening is an efficient solution adopted by the fast-developing zebrafish to enable folding of the eye primordia, which contrasts with the proliferation-based mechanism used by amniotes.
3. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction

   Fabio Da Silva et al.

   Lineage tracing and genetic experiments resolve a long-standing controversy by showing that retinoic acid signaling is active in cardiomyocytes, both during development and after myocardial infarction, and protects damaged hearts from apoptosis.
4. 1. Cell Biology
   2. Developmental Biology

   Ciliary Hedgehog signaling regulates cell survival to build the facial midline

   Shaun Abrams, Jeremy F Reiter
5. 1. Cell Biology
   2. Developmental Biology

   Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

   Lianna W Wat et al.
6. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size

   Alessandro Bonfini et al.

   The nutrient composition of food alters both the size of gut epithelial cells and the ability of the stem cell niche to control tissue turnover, resulting in changes in size at the organ level.
7. 1. Cell Biology
   2. Developmental Biology

   Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope

   Robert Becker et al.

   Myogenin promotes centrosome attenuation and establishes the nuclear envelope as the dominant microtubule organization center via the scaffold protein AKAP6, which is required for the recruitment of centrosomal proteins.
8. 1. Cell Biology
   2. Developmental Biology

   Par3 cooperates with Sanpodo for the assembly of Notch clusters following asymmetric division of Drosophila sensory organ precursor cells

   Elise Houssin et al.

   Baz/Par3 and Sanpdo are required for clustering and activation of Notch receptors to allow intra-lineage private communication following asymmetric division of Drosophila epithelial cells.
9. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development

   Benoit Roch et al.

   A viable separation of function XRCC4 knock-in mutant mouse model recapitulates some aspects of XRCC4 deficiency in humans, notably the absence of immune deficiency.
10. 1. Cell Biology
    2. Developmental Biology

    SLC1A5 provides glutamine and asparagine necessary for bone development in mice

    Deepika Sharma et al.