Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Immunology and Inflammation

    HEB collaborates with TCR signaling to upregulate Id3 and enable γδT17 cell maturation in the fetal thymus

    Johanna S Selvaratnam, Juliana Dutra Barbosa da Rocha ... Michele K Anderson
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    Dual Inhibition of MYRF Cleavage by Its JM Region and PAN-1 CCT Gates Developmental Timing in C. elegans

    Zhimin Xu, Xiaoting Feng ... Yingchuan B Qi
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Ripply1 and Gsc collectively suppress anterior endoderm differentiation from prechordal plate progenitors

    Tao Cheng, Xiang Liu ... Peng-Fei Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Developmental Biology

    Mouse germline cysts contain a fusome-like structure that mediates oocyte development

    Madhulika Pathak, Allan C Spradling
    Mammalian oocytes utilize a conserved combination of cell cycle control, cytoskeletal organization, and polarity pathways that are fundamentally shared with other vertebrates and invertebrates.
    1. Developmental Biology
    2. Genetics and Genomics

    A genome-wide MAGIC kit for recombinase-independent mosaic analysis in Drosophila

    Yifan Shen, Ann T Yeung ... Chun Han
    A comprehensive toolkit enables genome-wide, recombinase-independent mosaic analysis in Drosophila, permitting clonal analysis of pericentromeric genes, deficiency chromosomes, and interspecific hybrids previously inaccessible to standard methods.
    1. Developmental Biology
    2. Genetics and Genomics

    Nup107 is a crucial regulator of torso-mediated metamorphic transition in Drosophila melanogaster

    Jyotsna Kawadkar, Pradyumna Ajit Joshi, Ram Kumar Mishra
    Y-complex nucleoporin, Nup107, can regulate ecdysone production by affecting the transcription of Halloween genes and levels of RTK receptor, torso, for the metamorphic transition from larva to pupa.
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression

    Elena Gracheva, Abigail Matt ... Chao Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel

    Yang Zhi, Luo Tingting ... Sun Yuhua
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Developmental Biology

    Progressive mural cell deficiencies across the lifespan in a foxf2 model of cerebral small vessel disease

    Merry Faye E Graff, Emma EM Heeg ... Sarah J Childs
    Loss of foxf2 in zebrafish leads to a reduced pericyte progenitor pool in embryos and progresses to severe cerebrovascular defects over the lifespan, suggesting that cerebral small vessel disease in adults has roots in development.
    1. Developmental Biology

    Primordial cardiomyocytes orchestrate myocardial morphogenesis and vascularization but are dispensable for regeneration

    Jisheng Sun, Lu Chen, Jinhu Wang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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Highlights

    1. Developmental Biology

    Fusome first for mammals

    Michael Buszczak, Anirban Dasgupta
    1. Developmental Biology
    2. Genetics and Genomics

    Written out of history

    Lisa M Thomann, Julie Batut
    1. Developmental Biology

    Special Issue: Reproductive health

    Wei Yan

Senior editors

  1. Albert Cardona
    University of Cambridge, United Kingdom
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Claude Desplan
    New York University, United States
  4. See more editors