Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Developmental Biology

    Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

    Corey D. Holman, Alexander P. Sakers ... Patrick Seale
    1. Developmental Biology
    2. Neuroscience

    Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries

    Sweta Parab, Olivia A Card ... Ryota L Matsuoka
    Novel and common angiogenic mechanisms crucial for fenestrated brain capillary formation have been identified.
    1. Developmental Biology

    Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor

    Arun Devotta, Hugo Juraver-Geslin ... Jean-Pierre Saint-Jeannet
    A combination of morpholino-based knockdowns, pharmacological inhibitors, and rescue assays reveal a novel role for natriuretic peptide signaling in the regulation of cell fates in the embryonic ectoderm.
    1. Developmental Biology
    2. Evolutionary Biology

    Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network

    Joaquín Letelier, Lorena Buono ... Juan R Martínez-Morales
    Depletion of vsx genes in zebrafish confirms a conserved role in bipolar cells specification across vertebrates, but do not interfere with the formation of the neural retina domain, which reveal an unexpected robustness of the genetic network sustaining the retina.
    1. Developmental Biology
    2. Neuroscience

    Back to the future: omnipresence of fetal influence on the human brain through the lifespan

    Kristine B. Walhovd, Stine Kleppe Krogsrud ... Didac Vidal-Piñeiro
    1. Developmental Biology

    Development: The hidden depths of zebrafish skin

    Yue Rong Tan, Megan Liaw, Chen-Hui Chen
    Single-cell transcriptome analysis of zebrafish cells clarifies the signalling pathways controlling skin formation and reveals that some cells produce proteins required for human teeth to acquire their enamel.
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    1. Cell Biology
    2. Developmental Biology

    The fat body cortical actin network regulates Drosophila inter-organ nutrient trafficking, signaling, and adipose cell size

    Rupali Ugrankar-Banerjee, Son Tran ... W Mike Henne
    Fat-body-specific loss of actin isoform Act5C disrupts fat body cell growth and fat storage, lipoprotein secretion, and insulin signaling, revealing a non-canonical role for the cortical actin cytoskeleton in nutrient signaling and inter-organelle trafficking.
    1. Cell Biology
    2. Developmental Biology

    The dark kinase STK32A regulates hair cell planar polarity opposite of EMX2 in the developing mouse inner ear

    Shihai Jia, Evan M Ratzan ... Michael R Deans
    The planar polarized organization of vestibular hair cells in the mouse inner ear is determined by the coordinated activities of the STK32A kinase and the transcription factor EMX2 to regulate the orphan receptor GPR156.
    1. Developmental Biology

    An important role for triglyceride in regulating spermatogenesis

    Charlotte F. Chao, Yanina-Yasmin Pesch ... Elizabeth J. Rideout

Highlights

    1. Developmental Biology

    Hidden depths in zebrafish skin

    Yue Rong Tan, Megan Liaw, Chen-Hui Chen
    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer
    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Mike Eisen
    Michael B Eisen
    HHMI, University of California, Berkeley, United States
  3. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  4. See more editors