Developmental Biology

Latest articles

1. 1. Developmental Biology

   Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells

   Yuqing Zhu, Kevin Cho ... James B Skeath
2. 1. Developmental Biology

   Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells

   Hiroki Tsutsumi, Tomoki Chiba ... Hiroshi Asahara
3. 1. Developmental Biology

   Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals

   Yi Wu, Weilin Guo ... Tao Yu

   Pu.1-P53 axis controls the turnover and maintenance of microglia by cell competition.
4. 1. Developmental Biology

   SoxB1 family members inhibit Wnt signaling to promote maturation and deposition of stable neuromasts by the zebrafish Posterior Lateral Line primordium

   Greg Palardy, Kyeong-won Yoo ... Ajay B Chitnis
5. 1. Cell Biology
   2. Developmental Biology

   Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

   Robert N Rainey, Sam D Houman ... Neil Segil
6. 1. Cell Biology
   2. Developmental Biology

   Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

   Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan

   Complementary biochemical and cell-biological approaches reveal that formin FHOD3-mediated actin elongation, rather than nucleation, is critical for maintaining cardiomyocyte sarcomeres.
7. 1. Cell Biology
   2. Developmental Biology

   Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis

   Azali Azlan, Li Zhu, Ryuya Fukunaga

   Sakura is expressed in female germlines, interacts with Otu, and is crucial for germline stem cell renewal and differentiation and oogenesis in Drosophila.
8. 1. Developmental Biology
   2. Computational and Systems Biology

   A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales

   Alice Gros, Jules Vanaret ... Sham Tlili
9. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation

   Li He, Jiayu Wen, Qi Dai

   PRDM16 directs BMP signaling outcomes by guiding SMAD complex genomic binding to repress neural stem cell proliferation and promote choroid plexus epithelial specification.
10. 1. Developmental Biology

    NR2F2 is required in the embryonic testis for fetal Leydig cell development

    Aitana Perea-Gomez, Natividad Bellido Carreras ... Marie-Christine Chaboissier

    NR2F2 regulates fetal Leydig cell differentiation and steroidogenesis in mouse testes, providing mechanistic insight into testis development and the etiology of 46,XY differences in sex development.