Developmental Biology

Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling

   Kara A Nelson, Kari F Lenhart ... Stephen DiNardo
2. 1. Developmental Biology

   Lung Development: Exploring a complex constellation of signaling pathways

   Nathaniel C Nelson, Matthias C Kugler

   Cells called alveolar myofibroblasts, which have a central role in the development of the lung after birth, receive an orchestrated input from a range of different signaling pathways.
3. 1. Developmental Biology

   Impaired myofibroblast proliferation is a central feature of pathologic post-natal alveolar simplification

   Imran S Khan, Christopher Molina ... Dean Sheppard

   Reduced lung myofibroblast proliferation is a unifying feature in multiple models of developmental emphysema and inhibition of myofibroblast proliferation is sufficient to cause this pathology.
4. 1. Developmental Biology

   Molecular, cellular, and developmental organization of the mouse vomeronasal organ at single cell resolution

   Max Henry Hills, Limei Ma ... C Ron Yu

   A transcriptomic atlas of the mouse vomeronasal organ reveals novel receptor co-expression patterns and provides a framework for understanding sensory neuron lineage and receptor specification.
5. 1. Developmental Biology

   Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene Scleraxis to Instruct Regeneration

   Yun Bai, Tyler Harvey ... Chen-Ming Fan
6. 1. Cell Biology
   2. Developmental Biology

   Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

   Qian Wang, Hongge Li ... Xin Zhang
7. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos

   Marius Regin, Yingnan Lei ... Claudia Spits

   Aneuploid human embryonic cells are eliminated by p53-mediated apoptosis in a gene dosage dependent manner.
8. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   Unified bursting strategies in ectopic and endogenous even-skipped expression patterns

   Augusto Berrocal, Nicholas C Lammers ... Michael B Eisen

   Drosophila melanogastereven-skipped enhancers control transcriptional bursting by modulating frequency and amplitude, regardless of varying transcription factor inputs, even when mutated to express in embryonic regions not under selective pressure.
9. 1. Developmental Biology
   2. Neuroscience

   Dynamic changes in subplate and cortical plate microstructure at the onset of cortical folding in vivo

   Siân Wilson, Daan Christiaens ... Kiho Im
10. 1. Developmental Biology
    2. Genetics and Genomics

    Rescuable sleep and synaptogenesis phenotypes in a Drosophila model of O-GlcNAc transferase intellectual disability

    Ignacy Czajewski, Bijayalaxmi Swain ... Daan MF van Aalten

    Modelling O-GlcNAc transferase intellectual disability reveals the roles of this post-translational modification in regulating normal axonal terminal morphology and maintaining appropriate sleep homeostasis, pharmacological and genetic rescues of O-GlcNAcylation highlight the complexities of addressing this disorder.