Developmental Biology

Developmental Biology

eLife publishes research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea

    Takefumi Kondo, Shigeo Hayashi
    The Drosophila tracheal fate is stabilized by the combination of transcriptional programs to control tissue architecture and tissue-level input sensitive to tubular geometry, ensuring the robust mechanism of organ determination.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish

    Shuguang Yu, Jie He
    The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity

    Chen Qiu et al.
    A Caenorhabitis elegans RNA-binding protein, FBF-2, modulates RNA sequence motif recognition through conformational change and partner protein interaction.
    1. Developmental Biology
    2. Neuroscience

    Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2

    Verity Johnson et al.
    ROBO isoforms with minute sequence variations have significant and distinct functions in axon guidance.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration

    Zhihao Jia et al.
    Inhibition of Polo-like kinase that has been shown to exhibit antitumor effect unexpectedly disrupts muscle stem cell function, leading to developmental and regenerative failures.

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Marianne E Bronner
    Marianne E Bronner
    California Institute of Technology, United States
  3. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  4. See more editors