A flexible framework for simulating and fitting generalized drift-diffusion models
Abstract
The drift-diffusion model (DDM) is an important decision-making model in cognitive neuroscience. However, innovations in model form have been limited by methodological challenges. Here, we introduce the generalized drift-diffusion model (GDDM) framework for building and fitting DDM extensions, and provide a software package which implements the framework. The GDDM framework augments traditional DDM parameters through arbitrary user-defined functions. Models are solved numerically by directly solving the Fokker-Planck equation using efficient numerical methods, yielding a 100-fold or greater speedup over standard methodology. This speed allows GDDMs to be fit to data using maximum likelihood on the full response time (RT) distribution. We demonstrate fitting of GDDMs within our framework to both animal and human datasets from perceptual decision-making tasks, with better accuracy and fewer parameters than several DDMs implemented using the latest methodology, to test hypothesized decision-making mechanisms. Overall, our framework will allow for decision-making model innovation and novel experimental designs.
Data availability
The two analyzed datasets, which have been previously published, are both is publicly available for download:1. Roitman & Shadlen, 2002, J Neurosci: https://shadlenlab.columbia.edu/resources/RoitmanDataCode.html2. Evans & Hawkins, 2019, Cognition: https://osf.io/2vnam/
Article and author information
Author details
Funding
National Institute of Mental Health (R01MH112746)
- John D Murray
The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.
Reviewing Editor
- Thorsten Kahnt, Northwestern University, United States
Version history
- Received: March 16, 2020
- Accepted: August 3, 2020
- Accepted Manuscript published: August 4, 2020 (version 1)
- Version of Record published: September 1, 2020 (version 2)
Copyright
© 2020, Shinn et al.
This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.
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